Folate Metabolism (Homo sapiens)

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24, 31841, 59, 67, 76, 137...1, 349817, 41, 98, 191, 250122, 27187, 1612812049109, 24190, 173, 28030893GlycogenesisStimulationCofactor conversionSelenoproteinsEnzymesis composed ofFrom intracellular part to the plasmaConversionNegative EffectMicronutrientsCofactorsSelenium statusLEGENDReactionProtein with polymorphismNecessary stimulationProtein tyrosine nitrationProstaglandins metabolismOther proteinsLipid peroxidationTranscription factorBindingOverarching processProcess or metabolism involved in Se PathwayMetabolitesBiomarker forLipoprotein melabolismCatalysisCleavageProtein*InhibitionIntracellularApoptosisMethylation reactionsNovo purine biosynthetic pathwayDNA oxidationPlasmaSLC46A1PGE1PGE2FOLR4NFkB2PGE1NFkB1PGF2aMCP1F2-Isoprostane8-Isoprostaglandin F2aRELASLC19A1FOLR3MCP1FOLR28-Isoprostaglandin F2aThromboxane A2PGE2PGF2ap53Thromboxane B2FOLR1Thromboxane B2F2-Isoprostane16213, 90, 93, 137, 146...48, 127114, 127, 193127, 18719, 401143329114316232219127, 18748, 12732932216216233MTHFD1*DHFRMTR*AHCYSHMTMATMTHFD2MSR*22, 7822, 247, 254, 29893121, 236, 296105, 241241, 262241248CBS60, 298NADP+NADP+NADP+NADP+NADP+NADP+NADP+MPOCatalaseMPONOS6, 191, 218, 2464098, 1586, 191, 218, 246CysteineCysteinePAI-1ThrombinPLGtPAThrombinPLGtPAFactor VIIFactor VIIPAI-1167, 196167, 204112167, 204112167, 196112112112112GPX 4H2O2GAR5,10-Methylene-THF10-Formyl-THF(11S)-hydroxymethylene-THF5,10-Methenyl-THF5-Formyl-THFDihydrofolateFGAR(11R)-hydroxymethylene-THF241109, 241241241241241236109, 241236, 2415-methyl-THFFolate5-methyl-THFFolate1, 85, 93, 162, 173...236236, 247SOD3SOD3RFK123H2OGPX 3GPX 3CTH298Heme60, 98, 158THF236NADPHNADPHNADPHNADPHNADPHNADPHNADPHGPX 6ManganeseManganeseFolic acidFolic acid82, 236, 25482, 236, 254GPX 2GPX 1RNS98, 281SHMTMTHFR*GARTMTHFS236, 254241241109, 241HomocysteineHomocysteine41, 134, 152, 196, 215...196SOD1Pyridoxal 5'-phosphatePyridoxal 5'-phosphate202, 26440, 202, 264L-ArginineSerineGlycineGlycine105, 241105, 241105, 24185APOBHDLSAA4LDLVLDLSAA2VLDL-TAGCholesterolACTHDL-CSAA3ACTHDL-CABCA1HDL/APOA1CholesteroloxLDLAPOA1-NO2TyrAPOA1FMNSAA1HDLoxLDLHDL/SAAVLDL-TAGSRB1APOBLDLLDLRVLDL/APOBAPOA1TAGTAGVLDL524226, 152, 195, 218, 271122, 179122525212226, 152, 218, 27145, 521616, 122, 17951122, 179122, 1795, 5152122122, 17945, 521225, 51122122122, 1955212226, 152, 195, 218, 2715226, 152, 218, 271122, 1951455216, 122O287FADCob(I)alaminCob(I)alaminCob(II)alaminFAD8-OHdG8-OHdG308224222, 78, 30522, 7830822, 78, 305ADPADPChlorineMagnesiumMagnesiumChlorineS-nitrosohomocysteineCystathionine134SOD2Serine105, 241ATPZincZincNOO3HOClHNO2NO2NO6, 90, 134, 2466, 246IL6FibrinogenIL4D-dimerTNFaIFNgsICAM-1IL4CSF1IL1BALBINSALBHbA1cINSRFibrinCRPIL2HBBIL10IL2CSF1IFNgIL1BHBA1D-dimerINSIL6IL10HbA1cFibrinogenFibrinTNFa270, 3097613, 265112, 204142, 26041, 31528, 215, 2601, 118631, 11826, 40, 116, 161, 260...41, 76, 260, 30967, 14616216220, 45, 309631462914253, 11213, 41, 118, 265146293155929112, 2042920, 45, 30967, 1465953, 112Riboflavin183O2 S-Adenosylmethionine S-Adenosylhomocysteine S-AdenosylmethionineMethionineMethionine S-Adenosylhomocysteine22, 93, 148, 23622, 148, 236199199, 236, 247236, 268236, 268ADPONOO/ONOOHNitrotyrosineNitrotyrosineTetrahydrobiopterin28128185ATPATPFructosamineGlucoseGlucoseFructosamine20, 296320, 2963IronIron209209FLAD168, 123