Selenium Micronutrient Network (Homo sapiens)

From WikiPathways

Revision as of 09:09, 8 March 2018 by Mkutmon (Talk | contribs)
Jump to: navigation, search
2119, 16, 26, 32, 70...41, 2249118710, 195, 235, 2631027, 109, 211, 24021161, 64, 25625117, 150212107159, 20066, 8311713318, 29, 65, 240130LEGENDCleavageGlycogenesisCa++ metabolismInflammation and immune responseMetabolic stressNegative EffectProcess or metabolism involved in Se PathwayTranscription factorConversionLeukotriene metabolismOther proteinsMetabolitesNecessary stimulationOverarching processMicronutrientsOxidative stressLipid peroxidationStatusProstaglandins metabolismLipoprotein melabolismBindingFrom intracellular part to the plasmaBiomarker forSelenium statusReactionSelenoproteinsProtein tyrosine nitrationis composed ofEnzymesCatalysisCofactorsInhibitionTryptophan metabolismCofactor conversionStimulationIntracellularNAD+ metabolismER protein foldingGlutathione metabolismDNA oxidationFolate metabolismPlasmaCOX2NFkB2COX1Linoleic acidPGE3ALAa-TocopherolPGI2Lipoxin B4Lipoxin B4RELAF2-IsoprostanePGI2NFkB1MDADGLAEPAEPAF2-IsoprostanePGD2PGH2MDADPAPGE2Lipoxin A4Linoleic acidDHAArachidonic acidArachidonic acidPGE2PGE18-Isoprostaglandin F2aLipoxin A4PGD2a-TocopherolPGE1Thromboxane B2PGF2aALAThromboxane B28-Isoprostaglandin F2aDPAPGH3PGF2aThromboxane A2PGG2DHA18235, 244152206804, 2068080, 87, 115, 172, 18235, 24419180182, 191, 196, 20638, 7321992, 146, 197, 199, 23624446, 1418073, 23715973732442193521917246, 14187, 11587, 1157320673, 145351597346, 1411522192067392, 102, 146, 197, 199...16, 80, 114, 141, 146...15, 73, 152Kynurenine150MTR91, 106TRXR1CBS36, 106IodineIodine113113KMO150R-Triiodothyronine (rT3)Thyroxine (T4)5-HETE15-HETE5,6-EpoxytetraeneTriiodothyronine (T3)5-HPETETriiodothyronine (T3)Thyroxine (T4)R-Triiodothyronine (rT3)5-HETE15-HETE32, 162, 172105, 11332, 162, 172105, 113105, 113105, 17017232, 162, 172105, 170219172, 219105, 170NADP+MPOCatalaseMPO27, 67, 88, 2232740, 211Uric acid41, 180CysteinePAI-1tPAThrombinPLGGGT1PAI-1tPAPLGFactor VIIFactor VIIThrombin74747474148, 227188148, 155148, 227148, 1557474GPX 4TRXR2Xantine oxidase49, 180PRDX5H2O2ALOX15BALOX5114, 151, 194, 199, 219158, 172CopperUric acid41, 180Vitamin B1289, 1165,10-Methylene-THFSelR109, 121Tryptophan117, 1505-methyl-THFSOD3PRDX1RFK93H2OGPX 3NiacinamideCTH106PNPO135Heme15, 36, 40, 211, 212NADPHLipoic acid235ManganeseFAD78Methionine sulfoxide109Dehydroascorbic acid17, 195Leukotriene A4144, 186NADPHFAD78THFHydroxykynurenine150Folic acid91NADP+NADPHSeleniumSelenium118118SelKSep1514718, 225, 240GPX 6GSH198Nicotinamidase117Calcium186Methionine109ManganeseNADPHFolic acid91FMN78SelenocysteineSelenideSelenophosphate105, 263105, 263105, 263CysteineLeukotriene C4Leukotriene C4186, 188GPX 326Dehydroascorbic acid195GPX 2SelP209Trx-S210, 195, 235Ascorbic acid17Lipoic acid235PRDX4GPX 1NADP+HomocysteineROSRNS107, 21117, 29, 49, 55, 56, 64...NADPHVitamin B1289, 116MTHFR91Homocysteine227SelTSelMSelPDIO2SelOSelHSelVSelNDIO1DIO3SelSSPS2SelI55, 65, 12020329, 216, 226105, 113105, 113, 26661, 203, 256133, 221105, 11364, 203105, 22090, 111, 201, 209203203SOD1Pyridoxal 5'-phosphate150SerineIron186HypoxanthinePRDX3GSR103CholesterolACTSRB1LDLRoxLDLAPOA1-NO2TyrHDL/SAAABCA1TAGACTTAGHDL/APOA1HDLVLDL-TAGFMNHDL-CoxLDLSAA3VLDL-TAGAPOBLDLHDL-CVLDLAPOA1APOA1SAA2VLDLLDLSAA1HDLSAA4CholesterolVLDL/APOBAPOB838383, 18183, 181, 222101, 2539, 66, 200, 22310148, 85, 2342229, 66, 102, 200, 223101838383, 18183, 22210183, 18110148, 85, 23481014883, 1819, 66, 102, 200, 2239, 66, 200, 223838383101101101, 253837883O2159Pyridoxal 5'-phosphate1508-OHdGFAD8-OHdG13013078PRDX2ADPLeukotriene D4Leukotriene D4188ChlorineCopperChlorineCystathionineFAD78SOD2Dihydrolipoate204, 235SerineNADP+ATPZincNADP+GSSGNADPHZincNiacinLeukotriene B4Leukotriene B4144144, 186Quinolinic Acid117, 150PMPO3HOClNOHNO2NONO267, 8867, 88NADP+GSH133, 144, 198HbA1cFLAPFibrinFibrinIL10HBBIL10IFNgCCL2IL6INSALBTNFaHBA1IFNgIL6FibrinogenINSD-dimerALBINSRCCL2sICAM-1CRPIL1BHbA1cFibrinogenIL1BD-dimersICAM-1TNFa26620174, 15525, 72, 129, 208, 25325, 72, 129, 20826642, 68, 1421043312068, 90, 26656, 20110412442, 68, 14212056, 201335, 33, 26674, 15572, 20858, 7412420158, 7415110456, 68, 120, 14990, 120, 1491045, 42, 102, 200SelW137, 198, 257Riboflavin143SOD3224TRXR110Ascorbate17, 195O2-“XanthineCalcium186Kynureninase150Methionine109ADPTrx-(SH)210, 235ONOO-/ONOOHNitrotyrosineNitrotyrosine107107ATPLeukotriene E4Leukotriene E4188Leukotriene F4FructosamineFructosamineGlucose168, 18825, 104124124Iron186HypoxanthineTRXR3FLAD193, 110Ascorbic acid17, 92, 236