IL-5 Signaling Pathway (Mus musculus)

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PM->NUDMolecule in the pathway(Protein-protein interaction)Molecular associationCytoplasmAutophosphorylationMitochondriaGORecruitmentDeacetylationPlasma membraneEnzyme complexSumoylationDReaction through unknown mechanisms/moleculesENEndoplasmic reticulumDTranslocationNUCY->NUDDesumoylationDDActivationDemethylationDCY->NUNucleusAccession Number: NetPath 17PM->NUCYGolgi apparatusProteins in a complex interactionControlCY->PMDDDDPMDECGlycosylationExtracellularInhibitionPM->NUCY->NUDLigandCY->MTGene SymbolDDeubiquitinationReceptorDMTMethylationProteolytic cleavageEndosomePalmitoylationDUbiquitinationPhosphorylationAcetylationERDDephosphorylationDCcnd3Pik3r2Stat5aHckPik3r1Alox5Stat5aStat5bNfkb1Akt1Gsk3aStat5bStat3Shc2Raf1ItgamMapk14Icam1Elk1Rapgef1Il5raCsf2rbIl5Il5KrasPrkcdMapk1CblPtpn6Nfkb1Il2rbSocs1Cdkn1bAtf2NfkbiaCsf2rbLynSdcbpAlox5Alox5apPik3cgSox4Unc119Pla2g4aICAM3Gsk3bSh2b2Rps6ka1BtkCtnnb1Mapk9Rap1gapCrklMap2k2JunPrkcbYwhazBaxFoxo3Itgb2Vav1Ctnnb1Grb2Stat1Jak1Il5raMapk3BaxHras1Rac1Jak2PrkcdHcls1Dnm2Shc1Ptpn11Ptk2bCSF2RBPim1SykCrkl


Description

No description

Comments

GenMAPP notes 
NetPath 17 - IL-5 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP127(r20949) with a 95% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
69175view18:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
67381view10:45, 26 June 2013Christine ChichesterOntology Term : 'interleukin-5 signaling pathway' added !
59065view21:02, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
41364view00:27, 2 March 2011MaintBotRemoved redundant pathway information and comments
34416view23:12, 9 December 2009MaintBotAutomatic update of empty xrefs
32688view22:49, 31 August 2009Khanspersadded xrefs
32687view22:45, 31 August 2009Khanspersadded xref
31399view20:48, 13 August 2009MaintBotFixed text labels
30812view23:55, 29 July 2009MaintBotConverted from Homo sapiens
20999view11:30, 14 November 2008MaintBot[[Pathway:Mus musculus:IL-5 NetPath 17]] moved to [[Pathway:WP151]]: Moved to stable identifier
8184view13:46, 7 January 2008MaintBot[[Pathway:Mouse:IL-5 NetPath 17]] moved to [[Pathway:Mus musculus:IL-5 NetPath 17]]: Renaming species
7712view16:12, 18 December 2007MaintBotfixed category names
7251view12:41, 4 November 2007MaintBotAdded categories to GPML
6462view22:19, 22 May 2007A.Pandeygpml file for [[Mouse:IL-5_NetPath_17]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Akt1GeneProduct11651 (Entrez Gene)
Alox5GeneProduct11689 (Entrez Gene)
Alox5apGeneProduct11690 (Entrez Gene)
Atf2GeneProduct11909 (Entrez Gene)
BaxGeneProduct12028 (Entrez Gene)
BtkGeneProduct12229 (Entrez Gene)
CSF2RBGeneProduct12983 (Entrez Gene)
CblGeneProduct12402 (Entrez Gene)
Ccnd3GeneProduct12445 (Entrez Gene)
Cdkn1bGeneProduct12576 (Entrez Gene)
CrklGeneProduct12929 (Entrez Gene)
Csf2rbGeneProductENSMUSG00000071713 (Ensembl)
Ctnnb1GeneProduct12387 (Entrez Gene)
Dnm2GeneProduct13430 (Entrez Gene)
Elk1GeneProduct13712 (Entrez Gene)
Foxo3GeneProduct56484 (Entrez Gene)
Grb2GeneProduct14784 (Entrez Gene)
Gsk3aGeneProduct606496 (Entrez Gene)
Gsk3bGeneProduct56637 (Entrez Gene)
HckGeneProduct15162 (Entrez Gene)
Hcls1GeneProduct15163 (Entrez Gene)
Hras1GeneProduct15461 (Entrez Gene)
ICAM3GeneProduct
Icam1GeneProduct15894 (Entrez Gene)
Il2rbGeneProduct16185 (Entrez Gene)
Il5GeneProduct16191 (Entrez Gene)
Il5raGeneProduct16192 (Entrez Gene)
ItgamGeneProduct16409 (Entrez Gene)
Itgb2GeneProduct16414 (Entrez Gene)
Jak1GeneProduct16451 (Entrez Gene)
Jak2GeneProduct16452 (Entrez Gene)
JunGeneProduct16476 (Entrez Gene)
KrasGeneProduct16653 (Entrez Gene)
LynGeneProduct17096 (Entrez Gene)
Map2k2GeneProduct26396 (Entrez Gene)
Mapk1GeneProduct26413 (Entrez Gene)
Mapk14GeneProduct26416 (Entrez Gene)
Mapk3GeneProduct26417 (Entrez Gene)
Mapk9GeneProduct26420 (Entrez Gene)
Nfkb1GeneProduct18033 (Entrez Gene)
NfkbiaGeneProduct18035 (Entrez Gene)
Pik3cgGeneProduct30955 (Entrez Gene)
Pik3r1GeneProduct18708 (Entrez Gene)
Pik3r2GeneProduct18709 (Entrez Gene)
Pim1GeneProduct18712 (Entrez Gene)
Pla2g4aGeneProduct18783 (Entrez Gene)
PrkcbGeneProduct18751 (Entrez Gene)
PrkcdGeneProduct18753 (Entrez Gene)
Ptk2bGeneProduct19229 (Entrez Gene)
Ptpn11GeneProduct19247 (Entrez Gene)
Ptpn6GeneProduct15170 (Entrez Gene)
Rac1GeneProduct19353 (Entrez Gene)
Raf1GeneProduct110157 (Entrez Gene)
Rap1gapGeneProduct110351 (Entrez Gene)
Rapgef1GeneProduct107746 (Entrez Gene)
Rps6ka1GeneProduct20111 (Entrez Gene)
SdcbpGeneProduct53378 (Entrez Gene)
Sh2b2GeneProduct23921 (Entrez Gene)
Shc1GeneProduct20416 (Entrez Gene)
Shc2GeneProduct216148 (Entrez Gene)
Socs1GeneProduct12703 (Entrez Gene)
Sox4GeneProduct20677 (Entrez Gene)
Stat1GeneProduct20846 (Entrez Gene)
Stat3GeneProduct20848 (Entrez Gene)
Stat5aGeneProduct20850 (Entrez Gene)
Stat5bGeneProduct20851 (Entrez Gene)
SykGeneProduct20963 (Entrez Gene)
Unc119GeneProduct22248 (Entrez Gene)
Vav1GeneProduct22324 (Entrez Gene)
YwhazGeneProduct22631 (Entrez Gene)

Annotated Interactions

No annotated interactions
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