Fatty Acid Beta Oxidation (Homo sapiens)

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Complete fatty acid beta-oxidation pathway for saturated and unsaturated fatty acids, developed and curated internally by BiGCaT Bioinformatics. This pathway was previously split into three parts plus a meta file for statistics. If you still have these you can replace all four with this single pathway.

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Ontology Terms



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94768view18:29, 5 October 2017EgonwMore mim annotation.
94765view16:01, 5 October 2017EgonwConverted labels to metabolite DataNode and added mim-type annotation to conversions, and converted stimulation to catalysis.
93218view13:52, 4 August 2017DeSlChanged 3-Oxododexanoyl-CoA ID to more stereospecific one.
79783view15:41, 16 April 2015MkutmonFixed unconnected lines
71172view11:13, 11 October 2013Mkutmonfix unconnected lines
70676view19:04, 26 August 2013Mkutmonconnected lines
68951view17:37, 8 July 2013MaintBotUpdated to 2013 gpml schema
59762view15:10, 7 March 2013EgonwConverted Labels into DataNode's.
56441view21:35, 7 January 2013EgonwAdded missing data source info for three data nodes.
45258view18:42, 7 October 2011AlexanderPicoOntology Term : 'fatty acid metabolism' added !
45257view18:42, 7 October 2011AlexanderPicoOntology Term : 'fatty acid metabolic pathway' added !
45256view18:42, 7 October 2011AlexanderPicoOntology Term : 'fatty acid degradation pathway' added !
45255view18:41, 7 October 2011AlexanderPicoOntology Term : 'fatty acid beta degradation pathway' added !
43430view15:34, 21 June 2011AdrienDefayChange all the TCA text label to a Pathway node with the gene ID and the correct database.
41108view23:22, 1 March 2011MaintBotRemoved redundant pathway information and comments
39785view15:47, 18 January 2011FerryJagersPeriodical save, work in progress
39784view15:37, 18 January 2011FerryJagersPeriodical save, work in progress
39783view15:27, 18 January 2011FerryJagersPeriodical save, work in progress
39782view14:55, 18 January 2011FerryJagersPeriodical save, work in progress
32874view22:19, 16 September 2009MaintBotChanged type for metabolites
31971view13:08, 14 August 2009MaintBotFixed group labels
20983view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:Fatty Acid Beta-oxidation BiGCaT]] moved to [[Pathway:WP143]]: Moved to stable identifier
14286view08:56, 22 May 2008Pahlesgrouping and connections ready, metabolites need to be checked
14155view15:38, 21 May 2008PahlesGrouping genes, connecting to reactions
14153view15:35, 21 May 2008PahlesPeriodical save, work in progress
14151view15:25, 21 May 2008PahlesPeriodical save, work in progress
14123view14:20, 21 May 2008Pahlespartly curated
14091view12:03, 21 May 2008SusanSmall adaption
13066view11:12, 17 May 2008MaintBotautomated metabolite conversion
11784view09:24, 29 April 2008MichielResized to make GenMAPP compatible
11777view18:52, 28 April 2008EveloModified description
10773view09:54, 22 February 2008MichielPosition correction
10772view09:48, 22 February 2008MichielModified description
10771view09:47, 22 February 2008MichielSpecify description
10770view09:43, 22 February 2008MichielCorrected unsaturated path
10769view09:38, 22 February 2008MichielAdded unsaturated fatty acid metabolism
10656view12:20, 21 February 2008Michiel
10650view12:07, 21 February 2008Michiel[[Pathway:Homo sapiens:Fatty Acid Beta-Oxidation]] moved to [[Pathway:Homo sapiens:Fatty Acid Beta-oxidation BiGCaT]]
10647view11:52, 21 February 2008MichielModified description
10645view11:48, 21 February 2008MichielCreation

External references


View all...
NameTypeDatabase referenceComment
(S)-3-Hydroxybutanoyl-CoAMetaboliteCHEBI:15453 (ChEBI)
(S)-3-Hydroxydecanoyl-CoAMetaboliteCHEBI:28325 (ChEBI)
(S)-3-Hydroxyhexadecanoyl-CoAMetaboliteCHEBI:27402 (ChEBI)
(S)-3-Hydroxyoctanoyl-CoAMetaboliteCHEBI:28632 (ChEBI)
(S)-3-Hydroxytetradecanoyl-CoAMetaboliteCHEBI:27466 (ChEBI)
2-trans-4-cis-decadienoyl-CoAMetaboliteCHEBI:29119 (ChEBI)
2-trans-dodecenoyl-CoAMetaboliteCHEBI:15471 (ChEBI)
3-Oxo-octanoyl-CoAMetaboliteCHEBI:28264 (ChEBI)
3-Oxododexanoyl-CoAMetabolite440604 (PubChem-compound)
3-Oxohexanoyl-CoAMetaboliteCHEBI:27648 (ChEBI)
3-Oxopalmitoyl-CoAMetaboliteCHEBI:15491 (ChEBI)
3-trans-decenoyl-CoAMetaboliteCHEBI:29126 (ChEBI)
ACADLGeneProduct33 (Entrez Gene)
ACADMGeneProduct34 (Entrez Gene)
ACADSGeneProduct35 (Entrez Gene)
ACADVLGeneProduct37 (Entrez Gene)
ACAS2GeneProduct55902 (Entrez Gene)
ACAT1GeneProduct38 (Entrez Gene)
ACSL1GeneProduct2180 (Entrez Gene)
ACSL3GeneProduct2181 (Entrez Gene)
ACSL4GeneProduct2182 (Entrez Gene)
ACSL5GeneProduct51703 (Entrez Gene)
ACSL6GeneProduct23305 (Entrez Gene)
Acetoacetyl-CoAMetabolite1420-36-6 (CAS)
Acetyl-CoAMetabolite72-89-9 (CAS)
Acyl-CoAMetabolite9029-97-4 (CAS)
Butanoyl-CoAMetaboliteCHEBI:15517 (ChEBI)
CHKBGeneProduct1120 (Entrez Gene)
CPT1AGeneProduct1374 (Entrez Gene)
CPT1BGeneProduct1375 (Entrez Gene)
CPT2GeneProduct1376 (Entrez Gene)
CRATGeneProduct1384 (Entrez Gene)
DCIGeneProduct1632 (Entrez Gene)
DECR1GeneProduct1666 (Entrez Gene)
DLDGeneProduct1738 (Entrez Gene)
Decanoyl-CoAMetaboliteCHEBI:28493 (ChEBI)
Dihydroxyacetone PhosphateMetabolite57-04-5 (CAS)
ECHS1GeneProduct1892 (Entrez Gene)
GCDHGeneProduct2639 (Entrez Gene)
GK2GeneProduct2712 (Entrez Gene)
GKGeneProduct2710 (Entrez Gene)
GPD2GeneProduct2820 (Entrez Gene)
GlutarateMetabolite743 (PubChem-compound)
Glutaryl-CoAMetabolite103192-48-9 (CAS)
Glyceraldehyde-3-PhosphateMetabolite591-57-1 (CAS)
GlycerolMetabolite56-81-5 (CAS)
HADHAGeneProduct3030 (Entrez Gene)
HADHBGeneProduct3032 (Entrez Gene)
HADHSCGeneProduct3033 (Entrez Gene)
Hexanoyl-CoAMetaboliteCHEBI:27540 (ChEBI)
L-Glycerol-3-PhosphateMetaboliteCHEBI:15978 (ChEBI)
LIPCGeneProduct3990 (Entrez Gene)
LIPEGeneProduct3991 (Entrez Gene)
LIPFGeneProduct8513 (Entrez Gene)
LPLGeneProduct4023 (Entrez Gene)
Lauroyl-CoAMetabolite6244-92-4 (CAS)
Linoleoyl-CoAMetabolite40757-80-0 (CAS)
Myristoyl-CoAMetaboliteCHEBI:15532 (ChEBI)
PNPLA2GeneProduct57104 (Entrez Gene)
Palmitoyl-CoAMetaboliteCHEBI:15525 (ChEBI)
SLC25A20GeneProduct788 (Entrez Gene)
TCA cyclePathwayWP78 (WikiPathways)
TPI1GeneProduct7167 (Entrez Gene)
Trans-Dec-2-enoyl-CoAMetaboliteCHEBI:10723 (ChEBI)
Trans-Hex-2-enoyl-CoAMetaboliteCHEBI:28706 (ChEBI)
Trans-Oct-2-enoyl-CoAMetaboliteCHEBI:27537 (ChEBI)
TriacylglycerolMetaboliteCHEBI:17855 (ChEBI)
cis,cis-3,6-Dodecadienoyl-CoAMetaboliteCHEBI:28002 (ChEBI)

Annotated Interactions

No annotated interactions

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