Homologous recombination (Mus musculus)

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1Pol-deltaStrand invasiongamma radiation / genotoxic drugsMRN complexSister chromatidPol-deltaDamaged chromatidPol-deltaBrca2AtmRpa1Rad51Pold1Pold2Rad50Rad54bRad54bBrca2Rpa1Pold3Rad51Pold4Rad51Brca2Rad51Brca2Rad52Rpa1Mre11aNbnAtmRad52Rad52Rpa1


Homologous recombination, also known as general recombination, is a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical strands of DNA. Source: Wikipedia


This pathway was inferred from Homo sapiens pathway WP186(r29610) with a 100% conversion rate.

Quality Tags

Ontology Terms



  1. Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, James D. Watson; ''Molecular Biology of the Cell, 4th edition''; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mboc4&part=A747#A845, 2002


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69162view18:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67346view10:40, 26 June 2013Christine ChichesterOntology Term : 'homologous recombination pathway of double-strand break repair' added !
59062view21:01, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
41350view00:26, 2 March 2011MaintBotRemoved redundant pathway information and comments
36279view23:08, 17 March 2010KhanspersModified categories
35588view15:30, 12 February 2010ThomasModified description
35575view15:22, 12 February 2010Thomasadded literature
34755view23:19, 13 January 2010KhanspersModified categories
34750view23:09, 13 January 2010KhanspersAdded connectors
31862view12:34, 14 August 2009MaintBotFixed group labels
30870view00:13, 30 July 2009MaintBotNew pathway

External references


View all...
NameTypeDatabase referenceComment
AtmGeneProductENSMUSG00000034218 (Ensembl)
Brca2GeneProductENSMUSG00000041147 (Ensembl)
Mre11aGeneProductENSMUSG00000031928 (Ensembl)
NbnGeneProductENSMUSG00000028224 (Ensembl)
Pold1GeneProductENSMUSG00000038644 (Ensembl)
Pold2GeneProductENSMUSG00000020471 (Ensembl)
Pold3GeneProductENSMUSG00000030726 (Ensembl)
Pold4GeneProductENSMUSG00000024854 (Ensembl)
Rad50GeneProductENSMUSG00000020380 (Ensembl)
Rad51GeneProductENSMUSG00000027323 (Ensembl)
Rad52GeneProductENSMUSG00000030166 (Ensembl)
Rad54bGeneProductENSMUSG00000078773 (Ensembl)
Rpa1GeneProductENSMUSG00000000751 (Ensembl)

Annotated Interactions

No annotated interactions
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