Adipogenesis (Canis familiaris)

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1Adipocyte Secretory ProductsDifferentiated adipocyteInsulin Action GenesFully Differentiated Adipocyte MarkersMiscellaneousInhibitors of Preadipocyte to Adipocyte TransitionPossible Lipodystrophy GenesGrowth Factors/HormonesTranscription Factors/ModulatorsPreadipocyteBMP2CNTFRCISD1GH1E2F4RARAPNPLA3STAT5BADIPOQNR3C1EPAS1GDF10AGTPPARARORADLK1IRS2IL6GTF3ALPIN2DDIT3CEBPDMEF2DCFDLPIN3STAT5ACUGBP1SREBF1DVL1IRS4MIXL1HIF1APPARGNCOA2RBL2RETNRBL1FRZBRB1IL6STLEPSFRP4NAMPTTRIB3LIFRGADD45BGATA2PTGISMEF2AKLF15UCP1LMNAAGPAT2SERPINE1SP1WWTR1INSCREB1STAT2CTNNB1IRS1BMP3LIFADFPNR1H3EGR2SMAD3MBNL1FOXO1RXRANRIP1SOCS3GATA3SCDLPIN1PPARGC1APCK1ID3STAT6BMP4MEF2BASIPLOC486804RXRGGATA4KLF6BMP1BSCL2WNT10BPLINFASPRLRCEBPAIGF1NCOR1STAT3OSMEBF1HNF1ASTAT1MEF2CSLC2A4KLF7PCK2TNFLIPELPLFOXC2WNT1NCOR2LOC483120NDNSPOCK1KLF5E2F1SOCS1CEBPBGADD45AMIFNCOA1TGFB1IRS3LTWIST1ZMPSTE24WNT5BPPARDNR2F1AHRHMGA1CDKN1AFZD1


Description

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP236(r28133) with a 90% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
87031view14:50, 15 July 2016MkutmonOntology Term : 'signaling pathway pertinent to development' added !
68532view22:17, 5 July 2013MaintBotUpdated to 2013 gpml schema
40688view21:50, 1 March 2011MaintBotRemoved redundant pathway information and comments
35349view09:01, 12 February 2010MartijnVanIerselModified description
35345view08:58, 12 February 2010MartijnVanIerseladded lit. ref.
33974view18:29, 9 December 2009MaintBotAutomatic update of empty xrefs
30674view22:41, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADFPGeneProduct474720 (Entrez Gene)
ADIPOQGeneProduct403625 (Entrez Gene)
AGPAT2GeneProduct491249 (Entrez Gene)
AGTGeneProduct403783 (Entrez Gene)
AHRGeneProduct475251 (Entrez Gene)
ASIPGeneProduct492296 (Entrez Gene)
BMP1GeneProduct486127 (Entrez Gene)
BMP2GeneProduct477162 (Entrez Gene)
BMP3GeneProduct487826 (Entrez Gene)
BMP4GeneProduct490695 (Entrez Gene)
BSCL2GeneProduct476054 (Entrez Gene)
CDKN1AGeneProduct474890 (Entrez Gene)
CEBPAGeneProduct
CEBPBGeneProduct
CEBPDGeneProduct606783 (Entrez Gene)
CFDGeneProduct485095 (Entrez Gene)
CISD1GeneProduct479212 (Entrez Gene)
CNTFRGeneProduct442941 (Entrez Gene)
CREB1GeneProduct607922 (Entrez Gene)
CTNNB1GeneProduct477032 (Entrez Gene)
CUGBP1GeneProduct475979 (Entrez Gene)
DDIT3GeneProduct607439 (Entrez Gene)
DLK1GeneProduct490860 (Entrez Gene)
DVL1GeneProduct489593 (Entrez Gene)
E2F1GeneProduct485839 (Entrez Gene)
E2F4GeneProduct611243 (Entrez Gene)
EBF1GeneProduct479312 (Entrez Gene)
EGR2GeneProduct479219 (Entrez Gene)
EPAS1GeneProduct474578 (Entrez Gene)
FASGeneProduct486469 (Entrez Gene)
FOXC2GeneProduct489671 (Entrez Gene)
FOXO1GeneProduct477295 (Entrez Gene)
FRZBGeneProduct
FZD1GeneProduct482294 (Entrez Gene)
GADD45AGeneProduct
GADD45BGeneProduct485069 (Entrez Gene)
GATA2GeneProduct484626 (Entrez Gene)
GATA3GeneProduct487134 (Entrez Gene)
GATA4GeneProduct486079 (Entrez Gene)
GDF10GeneProduct611168 (Entrez Gene)
GH1GeneProduct
GTF3AGeneProduct477329 (Entrez Gene)
HIF1AGeneProduct480348 (Entrez Gene)
HMGA1GeneProduct442946 (Entrez Gene)
HNF1AGeneProduct486303 (Entrez Gene)
ID3GeneProduct403547 (Entrez Gene)
IGF1GeneProduct610255 (Entrez Gene)
IL6GeneProduct403985 (Entrez Gene)
IL6STGeneProduct403545 (Entrez Gene)
INSGeneProduct483665 (Entrez Gene)
IRS1GeneProduct486148 (Entrez Gene)
IRS2GeneProduct485548 (Entrez Gene)
IRS3LGeneProduct
IRS4GeneProduct492059 (Entrez Gene)
KLF15GeneProduct609067 (Entrez Gene)
KLF5GeneProduct612788 (Entrez Gene)
KLF6GeneProduct487151 (Entrez Gene)
KLF7GeneProduct478885 (Entrez Gene)
LEPGeneProduct403616 (Entrez Gene)
LIFGeneProduct403449 (Entrez Gene)
LIFRGeneProduct449478 (Entrez Gene)
LIPEGeneProduct403607 (Entrez Gene)
LMNAGeneProduct480124 (Entrez Gene)
LOC483120GeneProduct483120 (Entrez Gene)
LOC486804GeneProduct486804 (Entrez Gene)
LPIN1GeneProduct475670 (Entrez Gene)
LPIN2GeneProduct607640 (Entrez Gene)
LPIN3GeneProduct485876 (Entrez Gene)
LPLGeneProduct403626 (Entrez Gene)
MBNL1GeneProduct477116 (Entrez Gene)
MEF2AGeneProduct479021 (Entrez Gene)
MEF2BGeneProduct609739 (Entrez Gene)
MEF2CGeneProduct479155 (Entrez Gene)
MEF2DGeneProduct
MIFGeneProduct595146 (Entrez Gene)
MIXL1GeneProduct
NAMPTGeneProduct483267 (Entrez Gene)
NCOA1GeneProduct475684 (Entrez Gene)
NCOA2GeneProduct486989 (Entrez Gene)
NCOR1GeneProduct479515 (Entrez Gene)
NCOR2GeneProduct486242 (Entrez Gene)
NDNGeneProduct488693 (Entrez Gene)
NR1H3GeneProduct483625 (Entrez Gene)
NR2F1GeneProduct488908 (Entrez Gene)
NR3C1GeneProduct478047 (Entrez Gene)
NRIP1GeneProduct478385 (Entrez Gene)
OSMGeneProduct611921 (Entrez Gene)
PCK1GeneProduct403560 (Entrez Gene)
PCK2GeneProduct480255 (Entrez Gene)
PLINGeneProduct488735 (Entrez Gene)
PNPLA3GeneProduct609368 (Entrez Gene)
PPARAGeneProduct403654 (Entrez Gene)
PPARDGeneProduct481756 (Entrez Gene)
PPARGGeneProduct403606 (Entrez Gene)
PPARGC1AGeneProduct479127 (Entrez Gene)
PRLRGeneProduct479363 (Entrez Gene)
PTGISGeneProduct485919 (Entrez Gene)
RARAGeneProduct480526 (Entrez Gene)
RB1GeneProduct476915 (Entrez Gene)
RBL1GeneProduct477221 (Entrez Gene)
RBL2GeneProduct478127 (Entrez Gene)
RETNGeneProduct611540 (Entrez Gene)
RORAGeneProduct478328 (Entrez Gene)
RXRAGeneProduct491278 (Entrez Gene)
RXRGGeneProduct478989 (Entrez Gene)
SCDGeneProduct486839 (Entrez Gene)
SERPINE1GeneProduct403476 (Entrez Gene)
SFRP4GeneProduct483258 (Entrez Gene)
SLC2A4GeneProduct403673 (Entrez Gene)
SMAD3GeneProduct610902 (Entrez Gene)
SOCS1GeneProduct490006 (Entrez Gene)
SOCS3GeneProduct442949 (Entrez Gene)
SP1GeneProduct486507 (Entrez Gene)
SPOCK1GeneProduct474688 (Entrez Gene)
SREBF1GeneProduct403475 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT2GeneProduct481111 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT5BGeneProduct490969 (Entrez Gene)
STAT6GeneProduct100142679 (Entrez Gene)
TGFB1GeneProduct403998 (Entrez Gene)
TNFGeneProduct403922 (Entrez Gene)
TRIB3GeneProduct485819 (Entrez Gene)
TWIST1GeneProduct609156 (Entrez Gene)
UCP1GeneProduct403574 (Entrez Gene)
WNT10BGeneProduct486561 (Entrez Gene)
WNT1GeneProduct486560 (Entrez Gene)
WNT5BGeneProduct486756 (Entrez Gene)
WWTR1GeneProduct609743 (Entrez Gene)
ZMPSTE24GeneProduct482460 (Entrez Gene)

Annotated Interactions

No annotated interactions
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