Portal:CPTAC/Hallmark/Growth

From WikiPathways

(Difference between revisions)
Jump to: navigation, search
(Adding WP615)
Current revision (00:12, 11 October 2019) (view source)
(removed main cancer model)
 
Line 8: Line 8:
*[[Pathway:WP4204]] Tumor suppressor activity of SMARCB1
*[[Pathway:WP4204]] Tumor suppressor activity of SMARCB1
*[[Pathway:WP4284]] Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer
*[[Pathway:WP4284]] Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer
-
*[[Pathway:WP4018]] Pathways in clear cell renal cell carcinoma
 
*[[Pathway:WP615]] Senescence and Autophagy in Cancer
*[[Pathway:WP615]] Senescence and Autophagy in Cancer

Current revision

In addition to inducing and sustaining positively acting growth-stimulatory signals, cancer cells must also circumvent powerful programs that negatively regulate cell proliferation. Often these are tumor suppressor genes, that are often mutated in cancer cells. Two examples of this are RB and TP53. (Adapted from Hallmarks of cancer: the next generation, Hanahan and Weinberg, Cell 2011)

Personal tools