Portal:COVID-19
From WikiPathways
Welcome to the COVID-19 Pathways Portal on WikiPathways
This special subset of disease pathways is being highlighted during the current COVID-19 crisis. This content is released under a CC0 waiver to be freely used, re-used and distributed. Let us know if you add a new pathway or want to recommend one for this collection.
Covered Pathways
Pathway Collection
All pathways tagged with "Curation: COVID-19" will be linked to this overview table, to help keep track of the relevant pathways.
Download all human COVID19 pathways
Contact us
Send questions about WikiPathways to the wikipathways-discuss mailing list.
How to add a pathway to the portal
The list of Featured Pathways is not static and can be updated at any time. If you know of a pathway that should be added, please contact the administrator.
- See our Help section for New Contributor QuickStart, Editor's Palette Guide and Guidelines for Contributors.
Contribute
We are helping to coordinate an international effort to build and curate pathway models relevant to the COVID-19 pandemic. Review the resources below to see how you can get involved.
- growing collection of COVID-19 pathways. If you find or add a pathway at WikiPathways that should be included in this collection, please let us know.
- Published pathway figures related to COVID-19. Useful resource of previously published (but not modeled) pathways for direct translation as new pathways or to inform related pathway curation.
- Protein sequence alignments of SARS-CoV-2. Useful resource mapping SARS-CoV-2 proteins to those previously studied, including many solved structures.
- COVID-19 disease map initiative. An even broader community of pathway curators working with WikiPathways, Pathway Commons, Reactome, Cell Designer and more. Great community and set of resources, including repos, file shares, mailing list and Slack channel.
- Human Coronavirus protein identifiers and SARS-CoV-2 protein identifiers
- PubChem list of the COVID-19 Portal pathways
- KG COVID-19, a knowledge graph aggregating many sources as RDF
IMPORTANT: WikiPathways is dedicated to FAIR standards. All content at WikiPathways is freely available for use and reuse by a CC0 waiver.
Curation
There are curation tests being done, that check a number of drawing patterns, e.g. as agreed with the COVID-19 Disease Maps project. The reports can be found in this repository.
Featured Pathway
Endoplasmic reticulum stress response in Coronavirus infection (Homo sapiens)
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View all Featured Pathways for this Portal |
News
- 28 Oct. 2020 A longer paper from the whole COVID Disease Pathways community is available on bioRxiv
- 09 Sept. 2020 This portal was created with content from the Disease portal created in March
- 02 Sept. 2020 COVID19 tag created and added to relevant pathways
- 05 May 2020 The COVID-19 Disease Maps project paper was published
- 23 March 2020 As part of the Disease portal, a collection of COVID-19 disease pathways was started
This special subset of disease pathways is being highlighted during the current COVID-19 crisis. This content is released under a CC0 waiver to be freely used, reused and distributed. Let us know if you add a new pathway or want to recommend one for this collection. The current list of authors and contributors of content of this portal: Friederike Ehrhart, Alex Pico, Kristina Hanspers, Amber Koning, Rex D A B, Penny Nymark, Denise Slenter, Caroline Thorn, the Reactome project, Chris Evelo, Lauren Dupuis, Matthew Conroy, Martina Kutmon, Marvin Martens, and many more. We also thank the authors of all the cited articles (recursively). Call to Action: COVID-19We are helping to coordinate an international effort to build and curate pathway models relevant to the COVID-19 pandemic. Review the resources below to see how you can get involved.
IMPORTANT: WikiPathways is dedicated to FAIR standards. All content at WikiPathways is freely available for use and reuse by a CC0 waiver. |
![]() Part of the COVID-19 Disease Map project A paper about this project was published in Scientific Data. |
SARS-CoV-2 Pathways
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Collaborative project for curation of biological processes involved in the COVID-19 disease after SARS-Cov-2 infection. | invalid pathway title: exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/3/3c/WP4860_111831.svg:
SARS-CoV-2 includes a novel Orf10 that interacts with muliple members of the Cullin 2 ubiquitin ligase complex. | invalid pathway title: exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/f/f5/WP4868_111831.svg:
The induction and signaling of type I interferon with specific SARS-CoV-2 protein and relevant drug. | invalid pathway title: exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/4/4b/WP4927_111831.svg:
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Orf3a from SARS-CoV has been shown to bind TRAF3 and activate the NLRP3 inflammasome. | invalid pathway title: exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/d/db/WP4883_111831.svg:
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Experimental pathway to investigate overlap of virus-host interaction and adverse outcome pathways | invalid pathway title: exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/0/0b/WP4884_111831.svg:
Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis |
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Other coronaviruses: MERS, SARS-CoV, etc
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Lipid metabolism alternations that are related to infection by the corona virus. | invalid pathway title: exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/2/24/WP4863_111831.svg:
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More about ACE2
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