Small Ligand GPCRs (Bos taurus)

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CannabinoidLysophosphatidicAcidProstanoidsMelatoninPlatelet ActivatingTBXA2RLPAR1S1PR2PTGER2CNR1FPS1PR1CNR2PTGER4PTAFRMTNR1BS1PR3Gq/G11 PathwayGPR50PTGIREP1Gi PathwayGq/G11 PathwayMTNR1APTGER3PTGDRS1PR4


Description

G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: Wikipedia These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP247(74422) with a 94.0% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
102207view20:01, 10 December 2018EgonwBetter ID for the ligand.
96079view18:45, 15 February 2018KhanspersModified description
80793view15:26, 30 June 2015Mkutmonhomology conversion
71417view19:02, 17 October 2013MaintBotAutomated update of data sources
63377view23:07, 9 May 2013MaintBotUpdated to 2013 gpml schema
62707view23:18, 1 May 2013MaintBotUpdated UniProt data source
40549view19:31, 1 March 2011MaintBotRemoved redundant pathway information and comments
33789view00:12, 9 December 2009MaintBotAutomatic update of empty xrefs
33619view10:01, 1 December 2009MaintBotRemoved group label
31631view22:22, 13 August 2009MaintBotFixed text labels
30540view21:56, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CNR1GeneProductENSBTAG00000046006 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1268
CNR2GeneProductENSBTAG00000019371 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1269
CannabinoidMetaboliteCHEBI:67194 (ChEBI)
EP1GeneProductENSBTAG00000017041 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5731
FPGeneProductENSBTAG00000015902 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5737
GPR50GeneProductENSBTAG00000005950 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000102195
Gi PathwayPathwayWP35 (WikiPathways)
Gq/G11 PathwayPathwayWP35 (WikiPathways)
LPAR1GeneProductENSBTAG00000009654 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1902
Lysophosphatidic AcidMetaboliteCHEBI:32957 (ChEBI)
MTNR1AGeneProductENSBTAG00000046938 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4543
MTNR1BGeneProduct
MelatoninMetaboliteCHEBI:16796 (ChEBI)
PTAFRGeneProductENSBTAG00000027051 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5724
PTGDRGeneProductENSBTAG00000006703 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5729
PTGER2GeneProductENSBTAG00000002163 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5732
PTGER3GeneProductENSBTAG00000019230 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5733
PTGER4GeneProductENSBTAG00000014972 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5734
PTGIRGeneProductENSBTAG00000014585 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5739
ProstanoidsMetaboliteCHEBI:26347 (ChEBI)
S1PR1GeneProductENSBTAG00000005990 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1901
S1PR2GeneProductENSBTAG00000002738 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9294
S1PR3GeneProductENSBTAG00000011374 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1903
S1PR4GeneProductENSBTAG00000000381 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8698
TBXA2RGeneProductENSBTAG00000014944 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6915

Annotated Interactions

No annotated interactions
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