p38 MAPK Signaling Pathway (Pan troglodytes)

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?Right click for comments?Stress: Osmotic shockg-radiation, AnisomycinDNA transcriptionApoptosisCytokines Production,Apoptosis, etc.??TranslationFASL, InflammatoryCytokines, UV, etc.Growth Factors, UVTrophic Factors, etc.?CDC42TGFBR1MAPK14PLA2G4AMKNK1MAP3K9MAP3K5MAPKAPK2RIPK1MAXRASGRF1MAPKAPK2MAPK14RAC1HRASMAP3K1MEF2DMAP3K7HSPB1STAT1DDIT3SHC1MYCGRB2TRAF2TGFB2RPS6KA5MAP2K4TRADDELK1MAP2K6HMGN1ATF2DAXXMAPKAPK5CREB1


Description

No description

Comments

GenMAPP remarks 
Converted to human by GenMAPP.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP400(r21524) with a 80% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

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  1. Lewis TS, Hunt JB, Aveline LD, Jonscher KR, Louie DF, Yeh JM, Nahreini TS, Resing KA, Ahn NG; ''Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry.''; Mol Cell, 2000 PubMed Europe PMC
  2. Kyriakis JM; ''Making the connection: coupling of stress-activated ERK/MAPK (extracellular-signal-regulated kinase/mitogen-activated protein kinase) core signalling modules to extracellular stimuli and biological responses.''; Biochem Soc Symp, 1999 PubMed Europe PMC
  3. Li S, Wattenberg EV; ''Cell-type-specific activation of p38 protein kinase cascades by the novel tumor promoter palytoxin.''; Toxicol Appl Pharmacol, 1999 PubMed Europe PMC
  4. Roberson MS, Zhang T, Li HL, Mulvaney JM; ''Activation of the p38 mitogen-activated protein kinase pathway by gonadotropin-releasing hormone.''; Endocrinology, 1999 PubMed Europe PMC
  5. Herlaar E, Brown Z; ''p38 MAPK signalling cascades in inflammatory disease.''; Mol Med Today, 1999 PubMed Europe PMC
  6. Ichijo H; ''From receptors to stress-activated MAP kinases.''; Oncogene, 1999 PubMed Europe PMC
  7. Wysk M, Yang DD, Lu HT, Flavell RA, Davis RJ; ''Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression.''; Proc Natl Acad Sci U S A, 1999 PubMed Europe PMC
  8. Tibbles LA, Woodgett JR; ''The stress-activated protein kinase pathways.''; Cell Mol Life Sci, 1999 PubMed Europe PMC

History

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CompareRevisionActionTimeUserComment
95746view13:50, 19 January 2018MkutmonHomology conversion update
95121view15:04, 16 November 2017Mkutmonadded missing homology converter comment source
71864view21:20, 18 October 2013MaintBotModified title
69264view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
67572view11:27, 26 June 2013DdiglesOntology Term : 'p38 MAPK signaling pathway' added !
41572view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
38248view21:26, 27 August 2010KhanspersRemoved receptor and protein complex graphics
38247view21:25, 27 August 2010Khanspers
35700view23:12, 12 February 2010KhanspersDescription and Bibliography
34300view22:05, 9 December 2009MaintBotAutomatic update of empty xrefs
33574view09:47, 1 December 2009MaintBotRemoved group label
31599view22:08, 13 August 2009MaintBotFixed text labels
30487view21:37, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ATF2GeneProduct
CDC42GeneProduct456609 (Entrez Gene)
CREB1GeneProduct459901 (Entrez Gene)
DAXXGeneProduct462613 (Entrez Gene)
DDIT3GeneProduct452017 (Entrez Gene)
ELK1GeneProduct
GRB2GeneProduct737245 (Entrez Gene)
HMGN1GeneProduct458552 (Entrez Gene)
HRASGeneProduct466302 (Entrez Gene)
HSPB1GeneProduct463488 (Entrez Gene)
MAP2K4GeneProduct455065 (Entrez Gene)
MAP2K6GeneProduct468310 (Entrez Gene)
MAP3K1GeneProduct
MAP3K5GeneProduct463023 (Entrez Gene)
MAP3K7GeneProduct462888 (Entrez Gene)
MAP3K9GeneProduct467498 (Entrez Gene)
MAPK14GeneProduct450161 (Entrez Gene)
MAPKAPK2GeneProduct744091 (Entrez Gene)
MAPKAPK5GeneProduct
MAXGeneProduct452972 (Entrez Gene)
MEF2DGeneProduct457396 (Entrez Gene)
MKNK1GeneProduct469189 (Entrez Gene)
MYCGeneProduct464393 (Entrez Gene)
PLA2G4AGeneProduct469617 (Entrez Gene)
RAC1GeneProduct
RASGRF1GeneProduct453575 (Entrez Gene) PDZ domain containing guanine nucleotide exchange
RIPK1GeneProduct462397 (Entrez Gene) receptor (TNFRSF)-interacting serine-threonine kinase 1
RPS6KA5GeneProduct739162 (Entrez Gene)
SHC1GeneProduct457351 (Entrez Gene)
STAT1GeneProduct
TGFB2GeneProduct457742 (Entrez Gene)
TGFBR1GeneProduct472992 (Entrez Gene)
TRADDGeneProduct454154 (Entrez Gene)
TRAF2GeneProduct

Annotated Interactions

No annotated interactions
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