Serotonin HTR1 Group and FOS Pathway (Homo sapiens)

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2433424038, 74, 76, 80, 106...65, 115, 143, 237, 324125, 188, 34456, 73, 89, 175, 196...2401533473479, 49, 99, 134, 156...119, 221, 32015, 5216, 91, 162, 327, 33924019553149, 276, 284, 34214, 47, 51, 63, 96...20, 83, 85, 114, 171...1834735, 36, 100, 138, 161...26, 43, 60, 92, 202...10, 108, 148, 2113, 5, 67, 69, 113...29, 34, 72, 105, 147...163, 347117, 136, 139, 191, 199...25382, 181, 226, 266, 29214158, 121, 230, 265, 35424022, 48, 90, 109, 210...15132, 70, 79, 183, 223...4, 7, 54, 66, 75...151123, 13062, 86, 118, 120, 154...11, 61, 124, 146, 160...1, 28, 37, 78, 102...116, 34841, 145, 190, 207, 275...347170, 192, 225, 235, 260...347101, 299159, 24923, 107, 112, 155, 24142, 95, 122, 137, 256...55, 246, 311, 3196, 98, 144, 204, 259...31, 19834727, 93, 97, 131, 178...50, 152, 213, 303, 32533, 44, 45, 111, 172...166, 269, 274, 27922718912, 19, 39, 71, 129...31730634721, 81, 128, 21234717, 37, 77, 102, 110...46167, 195, 31531729725, 30, 40, 64, 91...88, 127, 263, 270, 3508, 57, 87, 103, 157...Indirect RegulationDirect RegulationLEGENDProteinBindingFunctional Protein ClassPromoter BindingProtein ModificationSmall MoleculeSynthesis ReceptorRPS6KA5GNAI1RPS6KFOSMAPK1BRAFITPR1MAP2K2HTR1BMAPK3GNAI3ELK4RAP1APLCPtdIns3PMAP2K1PI3KGb/gHTR1EMAPK14GNAO1HTR1DRasPKCRHOARASGRP11,2-DiacetinMAP2K3HTR1ACREB1RASGRF11,4,5-Insp3PDPK1MAPKAPK2ELK1MAP2K6SerotoninMAP3K1SRFCALCIUMGNAI2HTR1FMAPKAPK3


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This pathway is courtesy of Ariadne Genomics Pathway Studio.

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Bibliography

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106177view12:07, 16 August 2019MaintBotHMDB identifier normalization
102357view19:43, 20 December 2018Fehrhartfixed unconnected lines
102125view17:03, 1 December 2018EgonwRemoved whitespace in PubMed identifiers.
74511view05:59, 27 April 2014EgonwLast batch of PubMed ID fixes.
74501view17:12, 26 April 2014EgonwMore PubMed ID fixes.
74499view16:58, 26 April 2014EgonwFixed PubMed IDs.
73767view00:49, 22 February 2014MaintBotupdating schema
49735view09:04, 25 July 2012AndraRDF Tidy
49638view10:31, 23 July 2012AndraRDF Tidy
49633view09:57, 23 July 2012AndraRDF Tidy
49625view09:24, 23 July 2012AndraRDF Tidy
49624view09:22, 23 July 2012AndraRDF Tidy
49621view08:51, 23 July 2012AndraRDF Tidy
49580view07:14, 21 July 2012AndraRDF Tidy
49556view19:33, 20 July 2012AndraRDF tidy
49540view09:59, 20 July 2012AndraCorrected references
49539view09:48, 20 July 2012AndraCorrected a erroneous pubmed reference
49534view09:06, 20 July 2012AndraCorrected a pubmed error
46093view03:28, 15 December 2011AlexanderPicoconverted more hugo to hgnc
45025view18:43, 6 October 2011ThomasOntology Term : 'serotonin signaling pathway' added !
41105view23:22, 1 March 2011MaintBotRemoved redundant pathway information and comments
39767view07:54, 17 January 2011AlexanderPico
34469view18:32, 10 December 2009MaintBotAutomatic update of empty xrefs
33424view14:53, 30 November 2009MaintBotRemoved group label
33185view17:56, 5 November 2009KhanspersModified categories
31150view04:01, 5 August 2009ArukeModified description
30189view21:58, 8 July 2009ArukePeriodical save, work in progress
30183view04:17, 8 July 2009ArukePeriodical save, work in progress
30177view18:15, 7 July 2009ArukeAdded legend
30176view18:05, 7 July 2009ArukePeriodical save, work in progress
30071view18:39, 30 June 2009ArukeSpecify description
30070view18:37, 30 June 2009ArukePeriodical save, work in progress
30069view18:34, 30 June 2009ArukeSpecify description
30068view18:32, 30 June 2009ArukeSpecify description
30067view18:29, 30 June 2009ArukeSpecify description
30066view18:15, 30 June 2009ArukePeriodical save, work in progress
30065view18:11, 30 June 2009ArukeSpecify description
30064view17:58, 30 June 2009ArukePeriodical save, work in progress
30062view17:47, 30 June 2009ArukePeriodical save, work in progress
30061view17:33, 30 June 2009ArukePeriodical save, work in progress
30060view17:23, 30 June 2009ArukePeriodical save, work in progress
30059view17:12, 30 June 2009ArukePeriodical save, work in progress
30045view20:23, 29 June 2009ArukeSpecify description
30044view20:20, 29 June 2009ArukePeriodical save, work in progress
30043view20:17, 29 June 2009Aruke
30042view20:03, 29 June 2009ArukePeriodical save, work in progress
30041view19:42, 29 June 2009ArukePeriodical save, work in progress
30040view19:32, 29 June 2009ArukePeriodical save, work in progress
30038view16:35, 29 June 2009ArukeSpecify description
30037view15:50, 29 June 2009ArukePeriodical save, work in progress

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,2-DiacetinMetabolite102-62-5 (CAS) diacylglycerol
1,4,5-Insp3Metabolite85166-31-0 (CAS)
BRAFGeneProduct673 (Entrez Gene) v-raf murine sarcoma viral oncogene homolog B1
CALCIUMMetabolite7440-70-2 (CAS)
CREB1GeneProduct1385 (Entrez Gene) cAMP response element-binding protein 1
ELK1GeneProduct2002 (Entrez Gene) ELK1, member of ETS oncogene family
ELK4GeneProduct2005 (Entrez Gene) ETS domain-containing protein Elk-4 (SRF accessory protein 1)
FOSGeneProduct2353 (Entrez Gene) proto-oncogene protein c-fos
GNAI1Protein2770 (Entrez Gene)
GNAI2Protein2771 (Entrez Gene)
GNAI3Protein2773 (Entrez Gene)
GNAO1Protein2775 (Entrez Gene)
Gb/gComplex
HTR1AProtein3350 (Entrez Gene)
HTR1BProtein3351 (Entrez Gene)
HTR1DProtein3352 (Entrez Gene)
HTR1EProtein3354 (Entrez Gene)
HTR1FProtein3355 (Entrez Gene)
ITPR1GeneProduct3708 (Entrez Gene) inositol 1,4,5-triphosphate receptor 1
MAP2K1GeneProduct5604 (Entrez Gene) mitogen activated protein kinase kinase 1
MAP2K2GeneProduct5605 (Entrez Gene) mitogen activated protein kinase kinase 2
MAP2K3GeneProduct5606 (Entrez Gene) mitogen activated protein kinase kinase 3
MAP2K6GeneProduct5608 (Entrez Gene) mitogen activated protein kinase kinase 6
MAP3K1GeneProduct4214 (Entrez Gene) mitogen activated protein kinase kinase kinase 1
MAPK14GeneProduct1432 (Entrez Gene) mitogen activated protein kinase 14
MAPK1GeneProductMAPK1 (HGNC) mitogen activated protein kinase 1
MAPK3GeneProduct5595 (Entrez Gene) mitogen activated protein kinase 3
MAPKAPK2GeneProduct9261 (Entrez Gene) mitogen activated protein kinase 3
MAPKAPK3GeneProduct7867 (Entrez Gene) mitogen-activated protein kinase-activated protein kinase 3
PDPK1GeneProduct5170 (Entrez Gene) 3-phosphoinositide dependent protein kinase-1
PI3KGeneProduct5290 (Entrez Gene) phosphatidylinositol 3-kinase
PKCGeneProduct50818 (Entrez Gene) protein kinase C
PLCGeneProductphospholipase C
PtdIns3PGeneProductphosphatidylinositol 3,4,5-triphosphate
RAP1AGeneProduct5906 (Entrez Gene) RAS-related protein-1a
RASGRF1GeneProduct5923 (Entrez Gene) RAS protein-specific guanine nucleotide-releasing factor 1
RASGRP1GeneProduct10125 (Entrez Gene) RAS guanyl releasing protein 1
RHOAGeneProduct387 (Entrez Gene) ras homolog gene family, member A
RPS6KGeneProductFunctional Class RPS6K (ribosomal protein S6 kinase)
RPS6KA5GeneProduct9252 (Entrez Gene) ribosomal protein S6 kinase, polypeptide 5
RasGeneProductRAS oncogene homolog
SRFGeneProduct6722 (Entrez Gene) serum response factor
SerotoninMetaboliteHMDB00259 (HMDB)

Annotated Interactions

No annotated interactions

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