GPCRs, Class C Metabotropic glutamate, pheromone (Homo sapiens)

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Orphan GPRC5Metabotropic glutamateMetabotropic glutamate otherGABA-BGRM1GRM4GPRC5DGRM7GABBR1GRM3GPRC5AGPRC5CGRM5CASRGPR51GRM6GRM2GPRC5BGRM8


This pathway was created using the GPCRDB (Horn et al., 1998), The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.

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Ontology Terms



  1. Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, Edvardsen O, Campagne F, Vriend G; ''GPCRDB: an information system for G protein-coupled receptors.''; Nucleic Acids Res, 1998 PubMed Europe PMC Scholia
  2. Karchin R, Karplus K, Haussler D; ''Classifying G-protein coupled receptors with support vector machines.''; Bioinformatics, 2002 PubMed Europe PMC Scholia


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79715view08:38, 6 April 2015EgonwAdded the two references cited in the Description.
79714view08:33, 6 April 2015EgonwModified description
78580view14:50, 7 January 2015MaintBotadded missing graphIds
63205view20:56, 8 May 2013MaintBotUpdating gpml version
45341view20:23, 7 October 2011AlexanderPicoOntology Term : 'G protein mediated signaling pathway' added !
41097view23:21, 1 March 2011MaintBotRemoved redundant pathway information and comments
38914view20:51, 24 September 2010Khanspers
34574view22:05, 21 December 2009KhanspersModified description
34542view19:32, 21 December 2009KhanspersLayout
34541view19:28, 21 December 2009KhanspersModified description
32125view13:53, 14 August 2009MaintBotFixed group labels
21732view11:32, 14 November 2008MaintBot[[Pathway:Homo sapiens:GPCRDB Class C Metabotropic glutamate pheromone]] moved to [[Pathway:WP501]]: Moved to stable identifier
14204view01:05, 22 May 2008AlexanderPicoGrouped by class
13008view11:05, 17 May 2008MaintBotSticky edges patch by Sjoerd
8114view13:46, 7 January 2008MaintBot[[Pathway:Human:GPCRDB Class C Metabotropic glutamate pheromone]] moved to [[Pathway:Homo sapiens:GPCRDB Class C Metabotropic glutamate pheromone]]: Renaming species
7678view16:09, 18 December 2007MaintBotfixed category names
7422view12:42, 4 November 2007MaintBotAdded categories to GPML
19489view22:17, 22 May 2007BruceConklingpml file for [[Human:GPCRDB_Class_C_Metabotropic_glutamate_pheromone]]
6323view22:17, 22 May 2007Nsalomonisgpml file for [[Human:GPCRDB_Class_C_Metabotropic_glutamate_pheromone]]

External references


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NameTypeDatabase referenceComment
CASRGeneProduct846 (Entrez Gene)
GABBR1GeneProduct2550 (Entrez Gene)
GPR51GeneProduct9568 (Entrez Gene)
GPRC5AGeneProduct9052 (Entrez Gene)
GPRC5BGeneProduct51704 (Entrez Gene)
GPRC5CGeneProduct55890 (Entrez Gene)
GPRC5DGeneProduct55507 (Entrez Gene)
GRM1GeneProduct2911 (Entrez Gene)
GRM2GeneProduct2912 (Entrez Gene)
GRM3GeneProduct2913 (Entrez Gene)
GRM4GeneProduct2914 (Entrez Gene)
GRM5GeneProduct2915 (Entrez Gene)
GRM6GeneProduct2916 (Entrez Gene)
GRM7GeneProduct2917 (Entrez Gene)
GRM8GeneProduct2918 (Entrez Gene)

Annotated Interactions

No annotated interactions

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