Mitochondrial CIII assembly (Homo sapiens)

From WikiPathways

Revision as of 15:28, 9 May 2020 by Annabaya (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
1Complex IIIFe-S Transfer ComplexDimerisationMT-CYB Translational activityPre-cIII(2)UQCRBUQCC1UQCRC22Fe-2SUQCRC1UQCRFS1CYC1LYRM7BCS1Lheme bUQCRQMT-CYBTTC19UQCRHUQCR11UQCR10UQCC2UQCC3UQCC2MT-CYBUQCC1UQCC3heme bUQCC2UQCC1UQCC3MT-CYBUQCRBUQCRQUQCC3MT-CYBUQCRBUQCRQUQCRHUQCRC2UQCRC1CYC1LYRM7UQCRFS12Fe-2SMT-CYBUQCRBUQCRQUQCRHUQCRC2UQCRC1CYC1UQCR11UQCR10LYRM7UQCRFS1BCS1LMT-CYBUQCRBUQCRQUQCRHUQCRC2UQCRC1CYC1UQCR11UQCR10LYRM7UQCRFS1BCS1LTTC19


Description

Complex III or quinol-cytochrome c reductase performs electron transfer coupled to proton pumping. It occurs as a symmetrical, tightly bound dimer (referred to as cIII2). This dimerisation occurs prior to the pre CIII complex formation, annotated as pre-CIII(2). Each monomer is composed of a catalytic core containing MT-CYB, CYC1 and UQCRFS1. An additional seven subunits are required for stability and/or correct assembly of the enzyme, but are not involved in the catalysis, but .

Quality Tags

Ontology Terms

 

Bibliography

  1. Signes A, Fernandez-Vizarra E; ''Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes.''; Essays Biochem, 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
110420view15:28, 9 May 2020AnnabayaModified description
110419view15:23, 9 May 2020AnnabayaEdit labels
110388view16:08, 8 May 2020AnnabayaModified description
110371view15:23, 8 May 2020AnnabayaOntology Term : 'electron transport chain pathway' added !
110370view15:23, 8 May 2020AnnabayaOntology Term : 'oxidative phosphorylation pathway' added !
110355view13:40, 7 May 2020AnnabayaNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2Fe-2SMetaboliteCHEBI:30408 (ChEBI)
BCS1LGeneProductENSG00000074582 (Ensembl)
CYC1GeneProductENSG00000179091 (Ensembl)
LYRM7GeneProductENSG00000186687 (Ensembl)
MT-CYBGeneProductENSG00000198727 (Ensembl)
TTC19GeneProductENSG00000011295 (Ensembl)
UQCC1GeneProductENSG00000101019 (Ensembl)
UQCC2GeneProductENSG00000137288 (Ensembl)
UQCC3GeneProductENSG00000204922 (Ensembl)
UQCR10GeneProductENSG00000184076 (Ensembl)
UQCR11GeneProductENSG00000127540 (Ensembl)
UQCRBGeneProductENSG00000156467 (Ensembl)
UQCRC1GeneProductENSG00000010256 (Ensembl)
UQCRC2GeneProductENSG00000140740 (Ensembl)
UQCRFS1GeneProductENSG00000169021 (Ensembl)
UQCRHGeneProductENSG00000173660 (Ensembl)
UQCRQGeneProductENSG00000164405 (Ensembl)
heme bMetaboliteCHEBI:60344 (ChEBI)

Annotated Interactions

No annotated interactions

Personal tools