MAP3K1 role in promoting and blocking gonadal determination (Homo sapiens)

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1normalphosphorylationMale developmenthyper phosphorylationFemale developmentFemale developmentMale developmentMAPK1Catenin beta-1GSK3BMAPK11SOX9FRAT1ROCK1FGFR2MAP3K4GADD45GFOXL2SRYAXIN1ROCK1MAP3K1Catenin beta-1FGF9MAPK1MAP3K4RHOAMAPK11SOX9AXIN1WNT4AXIN1RHOAGSK3BMAP3K1


Description

No description

Quality Tags

Ontology Terms

 

Bibliography

  1. Ostrer H; ''Disorders of sex development (DSDs): an update.''; J Clin Endocrinol Metab, 2014 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
110081view09:11, 16 April 2020FehrhartModified description
110080view09:10, 16 April 2020FehrhartOntology Term : 'signaling pathway' added !
110079view09:09, 16 April 2020FehrhartAdded reference and connected unconnected line
109745view11:35, 30 March 2020TilmansModified title
109744view11:34, 30 March 2020TilmansOntology Term : '46 XY gonadal dysgenesis' added !
109743view11:33, 30 March 2020TilmansOntology Term : 'gonadal dysgenesis' added !
109742view11:33, 30 March 2020TilmansOntology Term : '46 XX gonadal dysgenesis' added !
109741view11:28, 30 March 2020TilmansNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AXIN1GeneProductENSG00000103126 (Ensembl)
Catenin beta-1ProteinB4DGU4 (Uniprot-TrEMBL)
FGF9GeneProductENSG00000102678 (Ensembl)
FGFR2GeneProductENSG00000066468 (Ensembl)
FOXL2GeneProductENSG00000183770 (Ensembl)
FRAT1GeneProductENSG00000165879 (Ensembl)
GADD45GGeneProductENSG00000130222 (Ensembl)
GSK3BGeneProductENSG00000082701 (Ensembl)
MAP3K1GeneProductENSG00000095015 (Ensembl)
MAP3K4GeneProductENSG00000085511 (Ensembl)
MAPK11GeneProductENSG00000185386 (Ensembl)
MAPK1GeneProductENSG00000100030 (Ensembl)
RHOAGeneProductENSG00000067560 (Ensembl)
ROCK1GeneProductENSG00000067900 (Ensembl)
SOX9GeneProductENSG00000125398 (Ensembl)
SRYGeneProductENSG00000184895 (Ensembl)
WNT4GeneProductENSG00000162552 (Ensembl)

Annotated Interactions

No annotated interactions

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