MAP3K1 role in promoting and blocking gonadal determination (Homo sapiens)

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normalphosphorylationFemale developmenthyper phosphorylationMale developmentMale developmentFemale developmentROCK1SRYWNT4FOXL2RHOAFGFR2SOX9Catenin beta-1MAP3K4FGF9AXIN1GADD45GGSK3BSOX9Catenin beta-1GSK3BRHOAAXIN1FRAT1MAP3K4ROCK1MAPK11MAP3K1AXIN1MAPK11MAPK1MAPK1MAP3K1


Description

No description

Quality Tags

Ontology Terms

 

Bibliography

  1. Ostrer H; ''Disorders of sex development (DSDs): an update.''; J Clin Endocrinol Metab, 2014 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
110081view09:11, 16 April 2020FehrhartModified description
110080view09:10, 16 April 2020FehrhartOntology Term : 'signaling pathway' added !
110079view09:09, 16 April 2020FehrhartAdded reference and connected unconnected line
109745view11:35, 30 March 2020TilmansModified title
109744view11:34, 30 March 2020TilmansOntology Term : '46 XY gonadal dysgenesis' added !
109743view11:33, 30 March 2020TilmansOntology Term : 'gonadal dysgenesis' added !
109742view11:33, 30 March 2020TilmansOntology Term : '46 XX gonadal dysgenesis' added !
109741view11:28, 30 March 2020TilmansNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AXIN1GeneProductENSG00000103126 (Ensembl)
Catenin beta-1ProteinB4DGU4 (Uniprot-TrEMBL)
FGF9GeneProductENSG00000102678 (Ensembl)
FGFR2GeneProductENSG00000066468 (Ensembl)
FOXL2GeneProductENSG00000183770 (Ensembl)
FRAT1GeneProductENSG00000165879 (Ensembl)
GADD45GGeneProductENSG00000130222 (Ensembl)
GSK3BGeneProductENSG00000082701 (Ensembl)
MAP3K1GeneProductENSG00000095015 (Ensembl)
MAP3K4GeneProductENSG00000085511 (Ensembl)
MAPK11GeneProductENSG00000185386 (Ensembl)
MAPK1GeneProductENSG00000100030 (Ensembl)
RHOAGeneProductENSG00000067560 (Ensembl)
ROCK1GeneProductENSG00000067900 (Ensembl)
SOX9GeneProductENSG00000125398 (Ensembl)
SRYGeneProductENSG00000184895 (Ensembl)
WNT4GeneProductENSG00000162552 (Ensembl)

Annotated Interactions

No annotated interactions

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