Host-pathogen interaction of human corona viruses - apoptosis (Homo sapiens)

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Apoptosis induction by human corona virus infection.

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Ontology Terms



  1. Fung TS, Liu DX; ''Human Coronavirus: Host-Pathogen Interaction.''; Annu Rev Microbiol, 2019 PubMed Europe PMC Scholia
  2. Li H, Zhu H, Xu CJ, Yuan J; ''Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.''; Cell, 1998 PubMed Europe PMC Scholia


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113801view09:33, 25 November 2020NhungPAnnotated protein 8a and updated protein S and N identifiers
111622view18:17, 30 August 2020Egonw
111365view05:33, 3 August 2020EgonwConverted two interacting Label's to DataNode's.
110821view07:59, 10 June 2020FehrhartModified description
110242view17:35, 29 April 2020EgonwReplaced a secondary ChEBI identifiers with a primary identifier.
110205view10:49, 24 April 2020Fehrhartupdated legend and labels
110200view20:39, 23 April 2020EgonwTyped proteins as Type="Protein"
109973view18:18, 8 April 2020AlexanderPicoupdated sars nodes per #covidpathways guidelines
109950view18:21, 7 April 2020MaintBotAdded two more identifiers.
109876view10:08, 3 April 2020Fehrhartadded information about tBID
109849view11:36, 2 April 2020Fehrhartchanged virus protein visualization
109819view14:57, 1 April 2020Fehrhartadded protein ID for M
109818view14:56, 1 April 2020Fehrhartadded some virus protein IDs
109639view19:00, 27 March 2020FehrhartOntology Term : 'apoptotic cell death pathway' added !
109638view18:59, 27 March 2020FehrhartOntology Term : 'disease pathway' added !
109637view18:59, 27 March 2020FehrhartOntology Term : 'viral infectious disease' added !
109636view18:59, 27 March 2020FehrhartOntology Term : 'severe acute respiratory syndrome' added !
109635view18:56, 27 March 2020FehrhartNew pathway

External references


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NameTypeDatabase referenceComment
3aGeneProductP59632 (Uniprot-TrEMBL)
3bGeneProductP59633 (Uniprot-TrEMBL)
6GeneProductP59634 (Uniprot-TrEMBL)
7aGeneProductP59635 (Uniprot-TrEMBL)
9bGeneProductP59636 (Uniprot-TrEMBL)
AKT1GeneProduct207 (Entrez Gene)
APAF1GeneProductENSG00000120868 (Ensembl)
BADGeneProductENSG00000002330 (Ensembl)
BAXGeneProductENSG00000087088 (Ensembl)
BBC3GeneProductENSG00000105327 (Ensembl) PUMA
BCL2GeneProductENSG00000171791 (Ensembl)
BCL2L11GeneProductENSG00000153094 (Ensembl) BIM
BCL2L1GeneProductENSG00000171552 (Ensembl)
BIDGeneProductENSG00000015475 (Ensembl)
CASP3GeneProductENSG00000164305 (Ensembl)
CASP7GeneProductENSG00000165806 (Ensembl)
CASP8GeneProductENSG00000064012 (Ensembl)
CASP9GeneProductENSG00000132906 (Ensembl)
Cytochrome CMetaboliteCHEBI:4062 (ChEBI)
EGeneProductP59637 (Uniprot-TrEMBL)
FADDGeneProductENSG00000168040 (Ensembl)
FASLGGeneProductENSG00000117560 (Ensembl)
MAPK11GeneProductENSG00000185386 (Ensembl)
MAPK12GeneProductENSG00000188130 (Ensembl)
MAPK13GeneProductENSG00000156711 (Ensembl)
MAPK14GeneProductENSG00000112062 (Ensembl)
MCL1GeneProductENSG00000143384 (Ensembl)
TNFGeneProductENSG00000232810 (Ensembl)
tBIDGeneProductENSG00000015475 (Ensembl) truncated BID

Annotated Interactions

No annotated interactions

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