Nucleotide Excision Repair (Homo sapiens)

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Damage recognitionTranscription-coupled repairStalled polymeraseTranscription factor II HXPC complexCul4-CSA complexERCC6GTF2H4GTF2H5POLD15'5'3'3'5'5'3'3'Pol IIRBX1CUL4ACUL4BERCC8DDB1DNA unwinding5'5'3'3'ERCC5XPARPA1CDK7MNAT1CCNHERCC2ERCC3GTF2H1GTF2H2GTF2H35'5'3'3'ERCC1ERCC4Incision5'5'3'3'Excision and DNA synthesisPOLD2POLD3POLD4POLEPOLE2POLE3POLE4PCNARFC1RFC2RFC3RFC4RFC55'5'3'3'LIG1LigationGlobal genome repairCul4-DDB complexRBX1CUL4ACUL4BDDB2DDB1XPCRAD23ARAD23BCETN25'5'3'3'RPA2RPA3


Description

Nucleotide Excision Repair - first draft

Quality Tags

Ontology Terms

 

Bibliography

  1. ''KEGG''; https://www.genome.jp/dbget-bin/www_bget?pathway+hsa03420,
  2. ''REPAIRtoire''; http://repairtoire.genesilico.pl/Pathway/2/,

History

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CompareRevisionActionTimeUserComment
108596view23:47, 9 January 2020KhanspersModified description
108048view00:38, 27 November 2019Khanspersadded references
108047view00:36, 27 November 2019KhanspersModified description
108046view00:27, 27 November 2019KhanspersModified description
108044view20:22, 26 November 2019KhanspersOntology Term : 'DNA repair pathway' added !
108043view20:21, 26 November 2019KhanspersOntology Term : 'nucleotide excision repair pathway' added !
108041view20:00, 26 November 2019KhanspersNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CCNHGeneProductENSG00000134480 (Ensembl)
CDK7GeneProductENSG00000134058 (Ensembl)
CETN2GeneProductENSG00000147400 (Ensembl)
CUL4AGeneProductENSG00000139842 (Ensembl)
CUL4BGeneProductENSG00000158290 (Ensembl)
DDB1GeneProductENSG00000167986 (Ensembl)
DDB2GeneProductENSG00000134574 (Ensembl)
ERCC1GeneProductENSG00000012061 (Ensembl)
ERCC2GeneProductENSG00000104884 (Ensembl)
ERCC3GeneProductENSG00000163161 (Ensembl)
ERCC4GeneProductENSG00000175595 (Ensembl)
ERCC5GeneProductENSG00000134899 (Ensembl)
ERCC6GeneProductENSG00000225830 (Ensembl)
ERCC8GeneProductENSG00000049167 (Ensembl)
GTF2H1GeneProductENSG00000110768 (Ensembl)
GTF2H2GeneProductENSG00000145736 (Ensembl)
GTF2H3GeneProductENSG00000111358 (Ensembl)
GTF2H4GeneProductENSG00000213780 (Ensembl)
GTF2H5GeneProductENSG00000272047 (Ensembl)
LIG1GeneProductENSG00000105486 (Ensembl)
MNAT1GeneProductENSG00000020426 (Ensembl)
PCNAGeneProductENSG00000132646 (Ensembl)
POLD1GeneProductENSG00000062822 (Ensembl)
POLD2GeneProductENSG00000106628 (Ensembl)
POLD3GeneProductENSG00000077514 (Ensembl)
POLD4GeneProductENSG00000175482 (Ensembl)
POLE2GeneProductENSG00000100479 (Ensembl)
POLE3GeneProductENSG00000148229 (Ensembl)
POLE4GeneProductENSG00000115350 (Ensembl)
POLEGeneProductENSG00000177084 (Ensembl)
RAD23AGeneProductENSG00000179262 (Ensembl)
RAD23BGeneProductENSG00000119318 (Ensembl)
RBX1GeneProductENSG00000100387 (Ensembl)
RFC1GeneProductENSG00000035928 (Ensembl)
RFC2GeneProductENSG00000049541 (Ensembl)
RFC3GeneProductENSG00000133119 (Ensembl)
RFC4GeneProductENSG00000163918 (Ensembl)
RFC5GeneProductENSG00000111445 (Ensembl)
RPA1GeneProductENSG00000132383 (Ensembl)
RPA2GeneProductENSG00000117748 (Ensembl)
RPA3GeneProductENSG00000106399 (Ensembl)
XPAGeneProductENSG00000136936 (Ensembl)
XPCGeneProductENSG00000154767 (Ensembl)

Annotated Interactions

No annotated interactions

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