Gluconeogenesis (Homo sapiens)

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Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids.
Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids.
Description adapted from [http://www.wikipedia.org Wikipedia].
Description adapted from [http://www.wikipedia.org Wikipedia].
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Derived from https://www.wikipathways.org/index.php/Pathway:WP534
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP534 CPTAC Assay Portal]</Comment>
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP534 CPTAC Assay Portal]</Comment>
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     <Graphics CenterX="416.9999999999999" CenterY="1056.8139534883708" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2027" />
+
     <Xref Database="Entrez Gene" ID="2027"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ENO1" GraphId="daabb" Type="GeneProduct" GroupRef="e7329">
   <DataNode TextLabel="ENO1" GraphId="daabb" Type="GeneProduct" GroupRef="e7329">
-
     <Graphics CenterX="416.9999999999999" CenterY="1037.8139534883708" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.9999999999999" CenterY="1037.8139534883708" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2023" />
+
     <Xref Database="Entrez Gene" ID="2023"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Glyceraldehyde 3P" GraphId="dd104" Type="Metabolite">
   <DataNode TextLabel="Glyceraldehyde 3P" GraphId="dd104" Type="Metabolite">
-
     <Graphics CenterX="271.0" CenterY="782.7639534883707" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="271.0" CenterY="782.7639534883707" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0001112" />
+
     <Xref Database="HMDB" ID="HMDB0001112"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Pyruvate" GraphId="e1b43" Type="Metabolite">
   <DataNode TextLabel="Pyruvate" GraphId="e1b43" Type="Metabolite">
-
     <Graphics CenterX="773.0" CenterY="1280.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="773.0" CenterY="1280.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000243" />
+
     <Xref Database="HMDB" ID="HMDB0000243"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Fructose 6P" GraphId="e2849" Type="Metabolite">
   <DataNode TextLabel="Fructose 6P" GraphId="e2849" Type="Metabolite">
-
     <Graphics CenterX="271.0" CenterY="584.4806201550373" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="271.0" CenterY="584.4806201550373" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:61527" />
+
     <Xref Database="ChEBI" ID="CHEBI:61527"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Malate" GraphId="e2cf7" Type="Metabolite">
   <DataNode TextLabel="Malate" GraphId="e2cf7" Type="Metabolite">
-
     <Graphics CenterX="851.0" CenterY="1223.8139534883708" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="851.0" CenterY="1223.8139534883708" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000744" />
+
     <Xref Database="HMDB" ID="HMDB0000744"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Glucose" GraphId="e51e3" Type="Metabolite">
   <DataNode TextLabel="Glucose" GraphId="e51e3" Type="Metabolite">
-
     <Graphics CenterX="271.0" CenterY="228.36666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="271.0" CenterY="228.36666666666667" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000122" />
+
     <Xref Database="HMDB" ID="HMDB0000122"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Triglyceride synthesis" GraphId="e62a7" Type="Pathway">
   <DataNode TextLabel="Triglyceride synthesis" GraphId="e62a7" Type="Pathway">
-
     <Graphics CenterX="622.1162464985995" CenterY="788.147286821704" Width="155.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="622.1162464985995" CenterY="788.147286821704" Width="155.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="WikiPathways" ID="WP325" />
+
     <Xref Database="WikiPathways" ID="WP325"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MPC2" GraphId="e62cc" Type="GeneProduct" GroupRef="ee3fe">
   <DataNode TextLabel="MPC2" GraphId="e62cc" Type="GeneProduct" GroupRef="ee3fe">
-
     <Graphics CenterX="633.0" CenterY="1290.147286821704" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="633.0" CenterY="1290.147286821704" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="25874" />
+
     <Xref Database="Entrez Gene" ID="25874"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MPC1" GraphId="e6f94" Type="GeneProduct" GroupRef="ee3fe">
   <DataNode TextLabel="MPC1" GraphId="e6f94" Type="GeneProduct" GroupRef="ee3fe">
-
     <Graphics CenterX="633.0" CenterY="1270.147286821704" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="633.0" CenterY="1270.147286821704" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="51660" />
+
     <Xref Database="Entrez Gene" ID="51660"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ENO2" GraphId="e7055" Type="GeneProduct" GroupRef="e7329">
   <DataNode TextLabel="ENO2" GraphId="e7055" Type="GeneProduct" GroupRef="e7329">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eno2" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Eno2"/>
-
     <Graphics CenterX="416.9999999999999" CenterY="1076.8139534883705" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.9999999999999" CenterY="1076.8139534883705" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2026" />
+
     <Xref Database="Entrez Gene" ID="2026"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Glycogen metabolism" GraphId="ea163" Type="Pathway">
   <DataNode TextLabel="Glycogen metabolism" GraphId="ea163" Type="Pathway">
-
     <Graphics CenterX="622.1162464985994" CenterY="425.08846329229254" Width="163.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="622.1162464985994" CenterY="425.08846329229254" Width="163.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="WikiPathways" ID="WP500" />
+
     <Xref Database="WikiPathways" ID="WP500"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="G6PC" GraphId="eb6d4" Type="GeneProduct">
   <DataNode TextLabel="G6PC" GraphId="eb6d4" Type="GeneProduct">
     <Comment>Not present in brain and muscle, so those organs can not produce their own glucose in the gluconeogenesis pathway</Comment>
     <Comment>Not present in brain and muscle, so those organs can not produce their own glucose in the gluconeogenesis pathway</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="G6pc" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="G6pc"/>
-
     <Graphics CenterX="416.8991596638656" CenterY="283.6274509803923" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.8991596638656" CenterY="283.6274509803923" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2538" />
+
     <Xref Database="Entrez Gene" ID="2538"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PCK1" GraphId="ec8e8" Type="GeneProduct">
   <DataNode TextLabel="PCK1" GraphId="ec8e8" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pck1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pck1"/>
-
     <Graphics CenterX="351.9999999999999" CenterY="1175.8139534883717" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="351.9999999999999" CenterY="1175.8139534883717" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5105" />
+
     <Xref Database="Entrez Gene" ID="5105"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PGK2" GraphId="f09d0" Type="GeneProduct" GroupRef="b58f7">
   <DataNode TextLabel="PGK2" GraphId="f09d0" Type="GeneProduct" GroupRef="b58f7">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgk2" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgk2"/>
-
     <Graphics CenterX="416.9999999999999" CenterY="910.8139534883709" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.9999999999999" CenterY="910.8139534883709" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5232" />
+
     <Xref Database="Entrez Gene" ID="5232"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Aspartate" GraphId="f3733" Type="Metabolite">
   <DataNode TextLabel="Aspartate" GraphId="f3733" Type="Metabolite">
-
     <Graphics CenterX="851.0" CenterY="1038.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="851.0" CenterY="1038.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000191" />
+
     <Xref Database="HMDB" ID="HMDB0000191"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SLC2A4" GraphId="f4bdb" Type="GeneProduct" GroupRef="c8496">
   <DataNode TextLabel="SLC2A4" GraphId="f4bdb" Type="GeneProduct" GroupRef="c8496">
-
     <Graphics CenterX="416.0" CenterY="185.655462184874" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.0" CenterY="185.655462184874" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6517" />
+
     <Xref Database="Entrez Gene" ID="6517"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Dihydroxyacetone-P" GraphId="f4df9" Type="Metabolite">
   <DataNode TextLabel="Dihydroxyacetone-P" GraphId="f4df9" Type="Metabolite">
-
     <Graphics CenterX="436.0" CenterY="788.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="436.0" CenterY="788.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0001473" />
+
     <Xref Database="HMDB" ID="HMDB0001473"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="P-enolpyruvate" GraphId="f56ff" Type="Metabolite">
   <DataNode TextLabel="P-enolpyruvate" GraphId="f56ff" Type="Metabolite">
-
     <Graphics CenterX="271.0" CenterY="1088.5139534883706" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="271.0" CenterY="1088.5139534883706" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000263" />
+
     <Xref Database="HMDB" ID="HMDB0000263"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FBP2" GraphId="f6085" Type="GeneProduct" GroupRef="de60a">
   <DataNode TextLabel="FBP2" GraphId="f6085" Type="GeneProduct" GroupRef="de60a">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fbp2" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Fbp2"/>
-
     <Graphics CenterX="416.99999999999994" CenterY="627.7635333203034" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.99999999999994" CenterY="627.7635333203034" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8789" />
+
     <Xref Database="Entrez Gene" ID="8789"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Aspartate" GraphId="f6f69" Type="Metabolite">
   <DataNode TextLabel="Aspartate" GraphId="f6f69" Type="Metabolite">
-
     <Graphics CenterX="527.6500000000001" CenterY="1038.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="527.6500000000001" CenterY="1038.147286821704" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000191" />
+
     <Xref Database="HMDB" ID="HMDB0000191"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SLC2A3" GraphId="f9637" Type="GeneProduct" GroupRef="c8496">
   <DataNode TextLabel="SLC2A3" GraphId="f9637" Type="GeneProduct" GroupRef="c8496">
-
     <Graphics CenterX="416.0" CenterY="165.655462184874" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.0" CenterY="165.655462184874" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6515" />
+
     <Xref Database="Entrez Gene" ID="6515"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Glucose-6P" GraphId="f9a44" Type="Metabolite">
   <DataNode TextLabel="Glucose-6P" GraphId="f9a44" Type="Metabolite">
     <Comment>Glucose-6-Phosphate (2-)</Comment>
     <Comment>Glucose-6-Phosphate (2-)</Comment>
-
     <Graphics CenterX="271.0" CenterY="321.2745098039219" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="271.0" CenterY="321.2745098039219" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:75052" />
+
     <Xref Database="ChEBI" ID="CHEBI:75052"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PGAM1" GraphId="fb96d" Type="GeneProduct" GroupRef="cbc7d">
   <DataNode TextLabel="PGAM1" GraphId="fb96d" Type="GeneProduct" GroupRef="cbc7d">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgam1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgam1"/>
-
     <Graphics CenterX="143.00000000000006" CenterY="993.4806201550373" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="143.00000000000006" CenterY="993.4806201550373" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5223" />
+
     <Xref Database="Entrez Gene" ID="5223"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="TCA Cycle" GraphId="fdfd0" Type="Pathway">
   <DataNode TextLabel="TCA Cycle" GraphId="fdfd0" Type="Pathway">
-
     <Graphics CenterX="917.5" CenterY="1343.147286821704" Width="95.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="917.5" CenterY="1343.147286821704" Width="95.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="WikiPathways" ID="WP78" />
+
     <Xref Database="WikiPathways" ID="WP78"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ALDOB" GraphId="ffa45" Type="GeneProduct" GroupRef="de5a2">
   <DataNode TextLabel="ALDOB" GraphId="ffa45" Type="GeneProduct" GroupRef="de5a2">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Aldob" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Aldob"/>
-
     <Graphics CenterX="416.99999999999994" CenterY="716.8139534883708" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="416.99999999999994" CenterY="716.8139534883708" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="229" />
+
     <Xref Database="Entrez Gene" ID="229"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Glucose-6P (open)" GraphId="f44c7" Type="Metabolite">
   <DataNode TextLabel="Glucose-6P (open)" GraphId="f44c7" Type="Metabolite">
     <Comment>D-Glucose-6-Phosphate (2-) open form</Comment>
     <Comment>D-Glucose-6-Phosphate (2-) open form</Comment>
-
     <Graphics CenterX="271.0" CenterY="393.2745098039219" Width="100.0" Height="20.0" ZOrder="32770" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="271.0" CenterY="393.2745098039219" Width="100.0" Height="20.0" ZOrder="32770" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:57584" />
+
     <Xref Database="ChEBI" ID="CHEBI:57584"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Fructose 6P (open)" GraphId="ddf6b" Type="Metabolite">
   <DataNode TextLabel="Fructose 6P (open)" GraphId="ddf6b" Type="Metabolite">
     <Comment>fructose-6-phosphate (2-) open form</Comment>
     <Comment>fructose-6-phosphate (2-) open form</Comment>
-
     <Graphics CenterX="271.0" CenterY="481.0" Width="100.0" Height="20.0" ZOrder="32774" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="271.0" CenterY="481.0" Width="100.0" Height="20.0" ZOrder="32774" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:57579" />
+
     <Xref Database="ChEBI" ID="CHEBI:57579"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GPI" GraphId="ae83f" Type="GeneProduct">
   <DataNode TextLabel="GPI" GraphId="ae83f" Type="GeneProduct">
     <Comment>glucose-6-phosphate isomerase</Comment>
     <Comment>glucose-6-phosphate isomerase</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="G6pc" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="G6pc"/>
-
     <Graphics CenterX="425.8991596638656" CenterY="452.6274509803923" Width="60.0" Height="20.0" ZOrder="32779" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="425.8991596638656" CenterY="452.6274509803923" Width="60.0" Height="20.0" ZOrder="32779" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2821" />
+
     <Xref Database="Entrez Gene" ID="2821"/>
   </DataNode>
   </DataNode>
   <Interaction GraphId="a040c">
   <Interaction GraphId="a040c">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="826.0" Y="1149.647286821704" GraphRef="b44e8" RelX="-0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="826.0" Y="1149.647286821704" GraphRef="b44e8" RelX="-0.5" RelY="1.0" ArrowHead="Arrow"/>
-
       <Point X="826.0" Y="1213.8139534883708" GraphRef="e2cf7" RelX="-0.5" RelY="-1.0" ArrowHead="mim-conversion" />
+
       <Point X="826.0" Y="1213.8139534883708" GraphRef="e2cf7" RelX="-0.5" RelY="-1.0" ArrowHead="mim-conversion"/>
-
       <Anchor Position="0.5732368896925858" Shape="None" GraphId="b33fb" />
+
       <Anchor Position="0.5732368896925858" Shape="None" GraphId="b33fb"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="a0c40">
   <Interaction GraphId="a0c40">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="185.00000000000006" Y="983.4806201550373" GraphRef="ebf7e" RelX="1.0" RelY="0.0" />
+
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     <Graphics CenterX="709.5833333333331" CenterY="909.8139534883703" Width="88.83333333333371" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="999999" />
+
     <Graphics CenterX="709.5833333333331" CenterY="909.8139534883703" Width="88.83333333333371" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="999999"/>
   </Label>
   </Label>
   <Shape GraphId="ec254">
   <Shape GraphId="ec254">
-
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" />
+
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/>
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
-
     <Graphics CenterX="811.0" CenterY="1218.647286821704" Width="348.0" Height="563.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" />
+
     <Graphics CenterX="811.0" CenterY="1218.647286821704" Width="348.0" Height="563.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/>
   </Shape>
   </Shape>
-
   <Group GroupId="b58f7" GraphId="a26a8" />
+
   <Group GroupId="b58f7" GraphId="a26a8"/>
-
   <Group GroupId="de60a" GraphId="b5d1f" />
+
   <Group GroupId="de60a" GraphId="b5d1f"/>
-
   <Group GroupId="e7329" GraphId="bebdc" Style="Complex" />
+
   <Group GroupId="e7329" GraphId="bebdc" Style="Complex"/>
-
   <Group GroupId="de5a2" GraphId="ca349" />
+
   <Group GroupId="de5a2" GraphId="ca349"/>
-
   <Group GroupId="c8496" GraphId="d645d" />
+
   <Group GroupId="c8496" GraphId="d645d"/>
-
   <Group GroupId="e1a06" GraphId="e13bc" Style="Complex" />
+
   <Group GroupId="e1a06" GraphId="e13bc" Style="Complex"/>
-
   <Group GroupId="cbc7d" GraphId="ebf7e" Style="Complex" />
+
   <Group GroupId="cbc7d" GraphId="ebf7e" Style="Complex"/>
   <Group GroupId="ee3fe" GraphId="f9a70" Style="Complex">
   <Group GroupId="ee3fe" GraphId="f9a70" Style="Complex">
     <BiopaxRef>efd</BiopaxRef>
     <BiopaxRef>efd</BiopaxRef>
   </Group>
   </Group>
-
   <InfoBox CenterX="673.9666666666667" CenterY="316.3" />
+
   <InfoBox CenterX="673.9666666666667" CenterY="316.3"/>
   <Biopax>
   <Biopax>
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">

Current revision

Error rendering pathway page

This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.

Pathway history

CompareRevisionActionTimeUserComment
107894view13:19, 9 November 2019MaijaUModified description
107893view13:16, 9 November 2019MaijaUNew pathway

Error details

exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/6/6d/WP4740_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
	at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
	at org.pathvisio.core.Engine.importPathway(Unknown Source)
	at org.pathvisio.core.util.Converter.main(Unknown Source)

<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/6/6d/WP4740_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 107894)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
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