Tryptophan metabolism (Homo sapiens)

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(Modified description)
(HMDB identifier normalization)
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</Comment>
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   <Comment Source="WikiPathways-category">Metabolic Process</Comment>
   <Comment Source="WikiPathways-category">Metabolic Process</Comment>
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     <Comment Source="GenMAPP remarks">4-(2-Aminophenyl)-2,4-dioxobutanoate</Comment>
     <Comment Source="GenMAPP remarks">4-(2-Aminophenyl)-2,4-dioxobutanoate</Comment>
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   <DataNode TextLabel="Indolelactate" GraphId="a09" Type="Metabolite">
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   <DataNode TextLabel="2-Aminomuconate" GraphId="a0d" Type="Metabolite">
     <Comment Source="GenMAPP remarks">2-Aminomuconate</Comment>
     <Comment Source="GenMAPP remarks">2-Aminomuconate</Comment>
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   <DataNode TextLabel="3-Methylindolepyruvate" GraphId="a5f" Type="Metabolite">
     <Comment Source="GenMAPP remarks">3-Methylindolepyruvate</Comment>
     <Comment Source="GenMAPP remarks">3-Methylindolepyruvate</Comment>
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   <DataNode TextLabel="7,8-Dihydro-7,8-dihydroxykynurenate" GraphId="a76" Type="Metabolite">
     <Comment Source="GenMAPP remarks">7,8-Dihydro-7,8-dihydroxykynurenate</Comment>
     <Comment Source="GenMAPP remarks">7,8-Dihydro-7,8-dihydroxykynurenate</Comment>
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   <DataNode TextLabel="Indole-3-acetate" GraphId="a96" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Indole-3-acetate</Comment>
     <Comment Source="GenMAPP remarks">Indole-3-acetate</Comment>
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   <DataNode TextLabel="Oxaloacetate" GraphId="af2" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Oxaloacetate</Comment>
     <Comment Source="GenMAPP remarks">Oxaloacetate</Comment>
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     <Comment Source="GenMAPP remarks">Anthranilate</Comment>
     <Comment Source="GenMAPP remarks">Anthranilate</Comment>
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   <DataNode TextLabel="Glucobrassicin" GraphId="b73" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Glucobrassicin</Comment>
     <Comment Source="GenMAPP remarks">Glucobrassicin</Comment>
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   <DataNode TextLabel="Indolepyruvate" GraphId="b7ce4" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Indolepyruvate</Comment>
     <Comment Source="GenMAPP remarks">Indolepyruvate</Comment>
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   <DataNode TextLabel="5-hydroxykynurenamine" GraphId="ba924" Type="Metabolite">
     <Comment Source="GenMAPP remarks">5-Hydroxykynurenamine</Comment>
     <Comment Source="GenMAPP remarks">5-Hydroxykynurenamine</Comment>
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   <DataNode TextLabel="3-Hydroxy-&#xA;L-kynurenine" GraphId="bb4" Type="Metabolite">
     <Comment Source="GenMAPP remarks">3-Hydroxy-L-kynurenine</Comment>
     <Comment Source="GenMAPP remarks">3-Hydroxy-L-kynurenine</Comment>
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   <DataNode TextLabel="5-Methoxyindoleacetate" GraphId="bbc" Type="Metabolite">
     <Comment Source="GenMAPP remarks">5-Methoxyindoleacetate</Comment>
     <Comment Source="GenMAPP remarks">5-Methoxyindoleacetate</Comment>
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   <DataNode TextLabel="2-Aminomuconate" GraphId="bfd" Type="Metabolite">
     <Comment Source="GenMAPP remarks">2-Aminomuconate</Comment>
     <Comment Source="GenMAPP remarks">2-Aminomuconate</Comment>
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   <DataNode TextLabel="N-acetylindoxyl" GraphId="bff4e" Type="Metabolite">
     <Comment Source="GenMAPP remarks">N-Acetylindoxyl</Comment>
     <Comment Source="GenMAPP remarks">N-Acetylindoxyl</Comment>
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   <DataNode TextLabel="4-(2-Amino-5-hydroxyphenyl)&#xA;-2,4-dioxobutanoate" GraphId="c2c74" Type="Metabolite">
     <Comment Source="GenMAPP remarks">4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate</Comment>
     <Comment Source="GenMAPP remarks">4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate</Comment>
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   <DataNode TextLabel="C01144" GraphId="c64" Type="Metabolite">
     <Comment Source="GenMAPP remarks">(S)-3-Hydroxybutanoyl-CoA</Comment>
     <Comment Source="GenMAPP remarks">(S)-3-Hydroxybutanoyl-CoA</Comment>
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   <DataNode TextLabel="3-Hydroxyanthranilate" GraphId="c7d" Type="Metabolite">
     <Comment Source="GenMAPP remarks">3-Hydroxyanthranilate</Comment>
     <Comment Source="GenMAPP remarks">3-Hydroxyanthranilate</Comment>
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   <DataNode TextLabel="Indole-3-acetaldoxime" GraphId="c94" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Indole-3-acetaldoxime</Comment>
     <Comment Source="GenMAPP remarks">Indole-3-acetaldoxime</Comment>
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   <DataNode TextLabel="N-formylanthranilate" GraphId="cc1e3" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Formylanthranilate</Comment>
     <Comment Source="GenMAPP remarks">Formylanthranilate</Comment>
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   <DataNode TextLabel="4,8-Dihydroxyquinoline" GraphId="ce96e" Type="Metabolite">
     <Comment Source="GenMAPP remarks">4,8-Dihydroxyquinoline</Comment>
     <Comment Source="GenMAPP remarks">4,8-Dihydroxyquinoline</Comment>
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   <DataNode TextLabel="Isophenoxazine" GraphId="cea" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Isophenoxazine</Comment>
     <Comment Source="GenMAPP remarks">Isophenoxazine</Comment>
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   <DataNode TextLabel="6-Hydroxyindolelactate" GraphId="d72" Type="Metabolite">
   <DataNode TextLabel="6-Hydroxyindolelactate" GraphId="d72" Type="Metabolite">
     <Comment Source="GenMAPP remarks">6-Hydroxyindolelactate</Comment>
     <Comment Source="GenMAPP remarks">6-Hydroxyindolelactate</Comment>
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-
     <Xref Database="ChEBI" ID="CHEBI:27524"/>
+
     <Xref Database="ChEBI" ID="CHEBI:27524" />
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   </DataNode>
   <DataNode TextLabel="3-Hydroxykynurenamine" GraphId="d7ac0" Type="Metabolite">
   <DataNode TextLabel="3-Hydroxykynurenamine" GraphId="d7ac0" Type="Metabolite">
     <Comment Source="GenMAPP remarks">3-Hydroxykynurenamine</Comment>
     <Comment Source="GenMAPP remarks">3-Hydroxykynurenamine</Comment>
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     <Xref Database="HMDB" ID="HMDB60281"/>
+
     <Xref Database="HMDB" ID="HMDB0060281" />
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   </DataNode>
   <DataNode TextLabel="Anthranilate" GraphId="da3" Type="Metabolite">
   <DataNode TextLabel="Anthranilate" GraphId="da3" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Anthranilate</Comment>
     <Comment Source="GenMAPP remarks">Anthranilate</Comment>
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-
     <Xref Database="Chemspider" ID="4573598"/>
+
     <Xref Database="Chemspider" ID="4573598" />
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   </DataNode>
   <DataNode TextLabel="5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin" GraphId="dac" Type="Metabolite">
   <DataNode TextLabel="5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin" GraphId="dac" Type="Metabolite">
     <Comment Source="GenMAPP remarks">5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate</Comment>
     <Comment Source="GenMAPP remarks">5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate</Comment>
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     <Xref Database="" ID="" />
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   </DataNode>
-
   <DataNode TextLabel="2-Formamino&#10;benzoylacetate" GraphId="db9" Type="Metabolite">
+
   <DataNode TextLabel="2-Formamino&#xA;benzoylacetate" GraphId="db9" Type="Metabolite">
     <Comment Source="GenMAPP remarks">2-Formaminobenzoylacetate</Comment>
     <Comment Source="GenMAPP remarks">2-Formaminobenzoylacetate</Comment>
-
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="6-Hydroxykynurenate" GraphId="dc46f" Type="Metabolite">
   <DataNode TextLabel="6-Hydroxykynurenate" GraphId="dc46f" Type="Metabolite">
     <Comment Source="GenMAPP remarks">6-Hydroxykynurenate</Comment>
     <Comment Source="GenMAPP remarks">6-Hydroxykynurenate</Comment>
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="Indole-3-acetaldehyde" GraphId="ddfcb" Type="Metabolite">
   <DataNode TextLabel="Indole-3-acetaldehyde" GraphId="ddfcb" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Indole-3-acetaldehyde</Comment>
     <Comment Source="GenMAPP remarks">Indole-3-acetaldehyde</Comment>
-
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-
     <Xref Database="Chemspider" ID="778"/>
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     <Xref Database="Chemspider" ID="778" />
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   </DataNode>
   <DataNode TextLabel="L-Tryptophanyl-tRNA" GraphId="dec" Type="Metabolite">
   <DataNode TextLabel="L-Tryptophanyl-tRNA" GraphId="dec" Type="Metabolite">
-
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-
     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="Quinolinate" GraphId="e1b" Type="Metabolite">
   <DataNode TextLabel="Quinolinate" GraphId="e1b" Type="Metabolite">
-
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     <Graphics CenterX="1386.0" CenterY="898.6666666666666" Width="69.33333333333333" Height="15.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle" />
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     <Xref Database="Chemspider" ID="2777129"/>
+
     <Xref Database="Chemspider" ID="2777129" />
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   </DataNode>
   <DataNode TextLabel="Cinnavalininate" GraphId="e22" Type="Metabolite">
   <DataNode TextLabel="Cinnavalininate" GraphId="e22" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Cinnavalininate</Comment>
     <Comment Source="GenMAPP remarks">Cinnavalininate</Comment>
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-
     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="Formyl-5-hydroxykynurenamine" GraphId="e425b" Type="Metabolite">
   <DataNode TextLabel="Formyl-5-hydroxykynurenamine" GraphId="e425b" Type="Metabolite">
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-
     <Xref Database="HMDB" ID="HMDB12948"/>
+
     <Xref Database="HMDB" ID="HMDB0012948" />
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   </DataNode>
   <DataNode TextLabel="3-Methoxyanthranilate" GraphId="e79" Type="Metabolite">
   <DataNode TextLabel="3-Methoxyanthranilate" GraphId="e79" Type="Metabolite">
     <Comment Source="GenMAPP remarks">3-Methoxyanthranilate</Comment>
     <Comment Source="GenMAPP remarks">3-Methoxyanthranilate</Comment>
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     <Xref Database="Chemspider" ID="7827589"/>
+
     <Xref Database="Chemspider" ID="7827589" />
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   </DataNode>
   <DataNode TextLabel="2-Oxoglutarate" GraphId="e9f" Type="Metabolite">
   <DataNode TextLabel="2-Oxoglutarate" GraphId="e9f" Type="Metabolite">
     <Comment Source="GenMAPP remarks">2-Oxoglutarate</Comment>
     <Comment Source="GenMAPP remarks">2-Oxoglutarate</Comment>
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-
     <Xref Database="Chemspider" ID="144236"/>
+
     <Xref Database="Chemspider" ID="144236" />
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   </DataNode>
   <DataNode TextLabel="2-Oxoadipate" GraphId="ec1" Type="Metabolite">
   <DataNode TextLabel="2-Oxoadipate" GraphId="ec1" Type="Metabolite">
     <Comment Source="GenMAPP remarks">2-Oxoadipate</Comment>
     <Comment Source="GenMAPP remarks">2-Oxoadipate</Comment>
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     <Xref Database="Chemspider" ID="19951093"/>
+
     <Xref Database="Chemspider" ID="19951093" />
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   </DataNode>
   <DataNode TextLabel="7,8-Dihydroxykynurenate" GraphId="ec4" Type="Metabolite">
   <DataNode TextLabel="7,8-Dihydroxykynurenate" GraphId="ec4" Type="Metabolite">
     <Comment Source="GenMAPP remarks">7,8-Dihydroxykynurenate</Comment>
     <Comment Source="GenMAPP remarks">7,8-Dihydroxykynurenate</Comment>
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     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="5-Hydroxyindoleacetate" GraphId="ed2" Type="Metabolite">
   <DataNode TextLabel="5-Hydroxyindoleacetate" GraphId="ed2" Type="Metabolite">
     <Comment Source="GenMAPP remarks">5-Hydroxyindoleacetate</Comment>
     <Comment Source="GenMAPP remarks">5-Hydroxyindoleacetate</Comment>
-
     <Graphics CenterX="1058.6666666666667" CenterY="89.66666666666667" Width="109.33333333333333" Height="15.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle"/>
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-
     <Xref Database="Chemspider" ID="10637170"/>
+
     <Xref Database="Chemspider" ID="10637170" />
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   </DataNode>
   <DataNode TextLabel="5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate" GraphId="f00" Type="Metabolite">
   <DataNode TextLabel="5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate" GraphId="f00" Type="Metabolite">
     <Comment Source="GenMAPP remarks">5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate</Comment>
     <Comment Source="GenMAPP remarks">5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate</Comment>
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     <Graphics CenterX="160.16666666666666" CenterY="1050.0" Width="231.66666666666666" Height="26.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle"/>
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     <Graphics CenterX="160.16666666666666" CenterY="1050.0" Width="231.66666666666666" Height="26.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle" />
-
     <Xref Database="Chemspider" ID="30791292"/>
+
     <Xref Database="Chemspider" ID="30791292" />
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   </DataNode>
-
   <DataNode TextLabel="3-(2-Aminoethyl)&#10;-1H-indol-5-ol" GraphId="f04b4" Type="Metabolite">
+
   <DataNode TextLabel="3-(2-Aminoethyl)&#xA;-1H-indol-5-ol" GraphId="f04b4" Type="Metabolite">
     <Comment Source="GenMAPP remarks">3-(2-Aminoethyl)-1H-indol-5-ol</Comment>
     <Comment Source="GenMAPP remarks">3-(2-Aminoethyl)-1H-indol-5-ol</Comment>
-
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     <Xref Database="Chemspider" ID="5013"/>
+
     <Xref Database="Chemspider" ID="5013" />
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   </DataNode>
   <DataNode TextLabel="Benzoate degradation via hydroxylation" GraphId="f32" Type="Metabolite">
   <DataNode TextLabel="Benzoate degradation via hydroxylation" GraphId="f32" Type="Metabolite">
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-
     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="(Z)-5-Oxohex-2-enedioate" GraphId="f44" Type="Metabolite">
   <DataNode TextLabel="(Z)-5-Oxohex-2-enedioate" GraphId="f44" Type="Metabolite">
     <Comment Source="GenMAPP remarks">(Z)-5-Oxohex-2-enedioate</Comment>
     <Comment Source="GenMAPP remarks">(Z)-5-Oxohex-2-enedioate</Comment>
-
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     <Graphics CenterX="1549.75" CenterY="1123.3333333333333" Width="114.5" Height="15.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle" />
-
     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   <DataNode TextLabel="5-(2'-Formylethyl)-4,6-dihydroxypicolinate" GraphId="f5a" Type="Metabolite">
   <DataNode TextLabel="5-(2'-Formylethyl)-4,6-dihydroxypicolinate" GraphId="f5a" Type="Metabolite">
     <Comment Source="GenMAPP remarks">5-(2'-Formylethyl)-4,6-dihydroxypicolinate</Comment>
     <Comment Source="GenMAPP remarks">5-(2'-Formylethyl)-4,6-dihydroxypicolinate</Comment>
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     <Graphics CenterX="160.0" CenterY="992.3333333333334" Width="238.33333333333334" Height="15.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle"/>
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     <Graphics CenterX="160.0" CenterY="992.3333333333334" Width="238.33333333333334" Height="15.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle" />
-
     <Xref Database="Chemspider" ID="30791294"/>
+
     <Xref Database="Chemspider" ID="30791294" />
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   </DataNode>
-
   <DataNode TextLabel="Formyl-N-acetyl-5-&#10;methoxykynurenamine" GraphId="f73" Type="Metabolite">
+
   <DataNode TextLabel="Formyl-N-acetyl-5-&#xA;methoxykynurenamine" GraphId="f73" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Formyl-N-acetyl-5-methoxykynurenamine</Comment>
     <Comment Source="GenMAPP remarks">Formyl-N-acetyl-5-methoxykynurenamine</Comment>
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-
     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="8-Methoxykynurenate" GraphId="f7f" Type="Metabolite">
   <DataNode TextLabel="8-Methoxykynurenate" GraphId="f7f" Type="Metabolite">
     <Comment Source="GenMAPP remarks">8-Methoxykynurenate</Comment>
     <Comment Source="GenMAPP remarks">8-Methoxykynurenate</Comment>
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     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   </DataNode>
   <DataNode TextLabel="Kynurenate" GraphId="f9bd7" Type="Metabolite">
   <DataNode TextLabel="Kynurenate" GraphId="f9bd7" Type="Metabolite">
     <Comment Source="GenMAPP remarks">4-Hydroxy-2-quinolinecarboxylic</Comment>
     <Comment Source="GenMAPP remarks">4-Hydroxy-2-quinolinecarboxylic</Comment>
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-
     <Xref Database="ChEBI" ID="CHEBI:18344"/>
+
     <Xref Database="ChEBI" ID="CHEBI:18344" />
   </DataNode>
   </DataNode>
   <DataNode TextLabel="2,3-Dihydroxyindole" GraphId="fa10c" Type="Metabolite">
   <DataNode TextLabel="2,3-Dihydroxyindole" GraphId="fa10c" Type="Metabolite">
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-
     <Xref Database="Chemspider" ID="20546"/>
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     <Xref Database="Chemspider" ID="20546" />
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   </DataNode>
   <DataNode TextLabel="2-Amino-3-carboxymuconate" GraphId="fa7" Type="Metabolite">
   <DataNode TextLabel="2-Amino-3-carboxymuconate" GraphId="fa7" Type="Metabolite">
     <Comment Source="GenMAPP remarks">2-Amino-3-carboxymuconate</Comment>
     <Comment Source="GenMAPP remarks">2-Amino-3-carboxymuconate</Comment>
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     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
   </DataNode>
   </DataNode>
   <DataNode TextLabel="5-Hydroxyindoleacetylglycine" GraphId="ffc" Type="Metabolite">
   <DataNode TextLabel="5-Hydroxyindoleacetylglycine" GraphId="ffc" Type="Metabolite">
-
     <Graphics CenterX="1495.5833333333333" CenterY="138.66666666666666" Width="133.16666666666666" Height="15.0" ZOrder="28672" FontWeight="Bold" FontSize="9" Valign="Middle" Color="0033cc"/>
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-
     <Xref Database="" ID=""/>
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     <Xref Database="" ID="" />
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   <DataNode TextLabel="CYP4F12" GraphId="a04" Type="GeneProduct" GroupRef="fcc2a">
   <DataNode TextLabel="CYP4F12" GraphId="a04" Type="GeneProduct" GroupRef="fcc2a">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CYP4F12 | cytochrome P450 family 4 subfamily ..."/>
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   <DataNode TextLabel="4.2.1.84" GraphId="a20" Type="GeneProduct">
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     <Xref Database="Enzyme Nomenclature" ID="4.2.1.84" />
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   <DataNode TextLabel="INDO" GraphId="a36" Type="GeneProduct">
   <DataNode TextLabel="INDO" GraphId="a36" Type="GeneProduct">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="INDO | indoleamine-pyrrole 23 dioxygenase"/>
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   <DataNode TextLabel="CYP2E1" GraphId="a45" Type="GeneProduct" GroupRef="fcc2a">
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   <DataNode TextLabel="GCDH" GraphId="a4c" Type="GeneProduct" GroupRef="a0df0">
     <Comment Source="GenMAPP remarks">predicted</Comment>
     <Comment Source="GenMAPP remarks">predicted</Comment>
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   <DataNode TextLabel="ALDH9A1" GraphId="a54" Type="GeneProduct" GroupRef="fa587">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ALDH9A1 | aldehyde dehydrogenase 9 family memb..."/>
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   <DataNode TextLabel="HRMT1L2" GraphId="a58" Type="GeneProduct">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="HRMT1L2 | HMT1 hnRNP methyltransferase-like 2 (..."/>
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   <DataNode TextLabel="ALDH2" GraphId="a61" Type="GeneProduct" GroupRef="fa587">
   <DataNode TextLabel="ALDH2" GraphId="a61" Type="GeneProduct" GroupRef="fa587">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ALDH2 | aldehyde dehydrogenase 2 family (mitoch..."/>
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   <DataNode TextLabel="ALDH1A2" GraphId="a63" Type="GeneProduct" GroupRef="fa587">
   <DataNode TextLabel="ALDH1A2" GraphId="a63" Type="GeneProduct" GroupRef="fa587">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ALDH1A2 | aldehyde dehydrogenase 1 family memb..."/>
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   <DataNode TextLabel="Formylkynurenine" GraphId="a65" Type="Metabolite">
   <DataNode TextLabel="Formylkynurenine" GraphId="a65" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Formylkynurenine</Comment>
     <Comment Source="GenMAPP remarks">Formylkynurenine</Comment>
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     <Xref Database="CAS" ID="1022-31-7" />
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   <DataNode TextLabel="2.6.1.27" GraphId="a6b" Type="GeneProduct" GroupRef="ac171">
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   <DataNode TextLabel="4.1.1.-" GraphId="ac3" Type="GeneProduct">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="Cyp2d2"/>
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   <DataNode TextLabel="ASMT" GraphId="ad3" Type="GeneProduct">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ASMT | acetylserotonin O-methyltransferase"/>
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ASMT | acetylserotonin O-methyltransferase" />
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   <DataNode TextLabel="Acetyl-CoA" GraphId="ad5" Type="Metabolite">
   <DataNode TextLabel="Acetyl-CoA" GraphId="ad5" Type="Metabolite">
     <Comment Source="GenMAPP remarks">Acetyl-CoA</Comment>
     <Comment Source="GenMAPP remarks">Acetyl-CoA</Comment>
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   <DataNode TextLabel="Indole" GraphId="aea" Type="Metabolite">
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   <DataNode TextLabel="CYP1A1" GraphId="b2a" Type="GeneProduct" GroupRef="fcc2a">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CYP1A1 | cytochrome P450 family 1 subfamily A..."/>
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   <DataNode TextLabel="OGDH" GraphId="b4d" Type="GeneProduct">
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   <DataNode TextLabel="MAOB" GraphId="b58" Type="GeneProduct">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAOB | monoamine oxidase B"/>
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   <DataNode TextLabel="ALDH3A2" GraphId="b74" Type="GeneProduct" GroupRef="fa587">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ALDH3A2 | aldehyde dehydrogenase 3 family memb..."/>
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   <DataNode TextLabel="MAOB" GraphId="b91" Type="GeneProduct">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAOB | monoamine oxidase B"/>
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   <DataNode TextLabel="DDC" GraphId="b94" Type="GeneProduct">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="DDC | dopa decarboxylase (aromatic L-amino acid..."/>
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   <DataNode TextLabel="HADH2" GraphId="b9e" Type="GeneProduct" GroupRef="c952c">
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="HADH2 | hydroxyacyl-Coenzyme A dehydrogenase t..."/>
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   <DataNode TextLabel="Benzoate degradation via hydroxylation" GraphId="cdc8a" Type="Pathway">
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   <DataNode TextLabel="AOX1" GraphId="cdf" Type="GeneProduct">
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   <DataNode TextLabel="DHCR24" GraphId="ce6" Type="GeneProduct">
   <DataNode TextLabel="DHCR24" GraphId="ce6" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">predicted</Comment>
     <Comment Source="GenMAPP remarks">predicted</Comment>
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   <DataNode TextLabel="5-Hydroxykynurenine" GraphId="d1c" Type="Metabolite">
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   <DataNode TextLabel="AADAT" GraphId="d29" Type="GeneProduct">
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   <DataNode TextLabel="ACMSD" GraphId="d37" Type="GeneProduct">
   <DataNode TextLabel="ACMSD" GraphId="d37" Type="GeneProduct">
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   <DataNode TextLabel="Xanthurenic acid" GraphId="d3967" Type="Metabolite">
   <DataNode TextLabel="Xanthurenic acid" GraphId="d3967" Type="Metabolite">
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   <DataNode TextLabel="N-Methylserotonin" GraphId="d53ba" Type="Metabolite">
   <DataNode TextLabel="N-Methylserotonin" GraphId="d53ba" Type="Metabolite">
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   <DataNode TextLabel="INDO" GraphId="d6b" Type="GeneProduct">
   <DataNode TextLabel="INDO" GraphId="d6b" Type="GeneProduct">
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   <DataNode TextLabel="Tryptamine" GraphId="d86" Type="Metabolite">
   <DataNode TextLabel="Tryptamine" GraphId="d86" Type="Metabolite">
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   <DataNode TextLabel="KYNU" GraphId="d8b" Type="GeneProduct">
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   <DataNode TextLabel="Phenylalanine, Tyrosine and &#xA;Tryptophan metabolism" GraphId="e336c" Type="Pathway">
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     <Xref Database="KEGG Compound" ID="C00877" />
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   <DataNode TextLabel="HAAO" GraphId="e8b" Type="GeneProduct">
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     <Comment Source="GenMAPP remarks">3-Indoleacetonitrile</Comment>
     <Comment Source="GenMAPP remarks">3-Indoleacetonitrile</Comment>
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     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAOB | monoamine oxidase B"/>
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Revision as of 12:09, 16 August 2019

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Pathway history

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CompareRevisionActionTimeUserComment
106518view23:30, 5 September 2019Khanspersadded reference
106203view12:09, 16 August 2019MaintBotHMDB identifier normalization
105847view23:14, 15 August 2019KhanspersModified description
104898view15:43, 23 June 2019EgonwReplaced secondary ChEBI identifiers with a primary identifiers.
104829view14:28, 19 June 2019Fehrhartadded some more metabolite IDs
104828view14:20, 19 June 2019Fehrhartadded metabolite IDs
104821view12:57, 19 June 2019FehrhartModified description
103977view02:10, 20 April 2019AlexanderPicoFixed EC6.3.2.-
102311view21:09, 17 December 2018KhanspersModified description
102310view21:08, 17 December 2018Khanspersremoved GenMAPP comment
94086view12:40, 18 August 2017DeSlModified description
93713view12:41, 11 August 2017DeSlModified description
85055view10:47, 10 April 2016EgonwReplaced a Wikipedia ID with a ChEBI ID.
79226view18:51, 15 March 2015EgonwAdded a number of missing metabolite Chemspider identifiers (based on IUPAC names).
77387view12:04, 4 September 2014EgonwAdded a number of missing metabolite Chemspider identifiers (based on IUPAC names).
77384view13:24, 3 September 2014EgonwReplace a bunch of Labels for metabolites with Metabolite DataNodes.
71269view22:00, 16 October 2013MaintBotAutomated update of data sources
69003view17:45, 8 July 2013MaintBotUpdated to 2013 gpml schema
61696view23:21, 16 April 2013MaintBotspecified data source Enzyme Nomenclature for EC numbers
61691view22:33, 16 April 2013MaintBotremoved data source without identifer
45056view19:46, 6 October 2011KhanspersOntology Term : 'tryptophan metabolic pathway' added !
43616view14:09, 8 July 2011AdrienDefayadd database identifier for Gycolysis
41177view23:42, 1 March 2011MaintBotRemoved redundant pathway information and comments
38843view17:41, 24 September 2010Khanspers
38697view19:07, 23 September 2010KhanspersAdded pathway links and changed arrows
38695view19:00, 23 September 2010KhanspersPeriodical save, work in progress
38694view18:50, 23 September 2010KhanspersPeriodical save, work in progress
34449view18:21, 10 December 2009MaintBotAutomatic update of empty xrefs
33850view00:49, 9 December 2009KhanspersAdded metabolites and connectors
33849view00:47, 9 December 2009KhanspersPeriodical save, work in progress
33848view00:35, 9 December 2009KhanspersPeriodical save, work in progress
33820view00:24, 9 December 2009KhanspersPeriodical save, work in progress
32439view17:17, 15 August 2009MaintBotFixed text labels
32112view13:48, 14 August 2009MaintBotFixed group labels
30270view20:18, 25 July 2009AlexanderPicostill fixing unsupported characters
30269view20:16, 25 July 2009AlexanderPicofixed unsupported characters in TextLabels
30268view20:13, 25 July 2009AlexanderPico
30267view20:11, 25 July 2009AlexanderPicofixed unsupported characters in TextLabels
21658view11:32, 14 November 2008MaintBot[[Pathway:Homo sapiens:Tryptophane Metabolism KEGG]] moved to [[Pathway:WP465]]: Moved to stable identifier
14841view08:35, 24 May 2008AlexanderPicoConnected!
14839view08:27, 24 May 2008AlexanderPicoPeriodical save, work in progress
14835view08:16, 24 May 2008AlexanderPicoPeriodical save, work in progress
14833view08:06, 24 May 2008AlexanderPicoPeriodical save, work in progress
14830view07:56, 24 May 2008AlexanderPicoPeriodical save, work in progress
14828view07:46, 24 May 2008AlexanderPicoPeriodical save, work in progress
13127view11:18, 17 May 2008MaintBotautomated metabolite conversion
8464view13:46, 7 January 2008MaintBot[[Pathway:Human:Tryptophane Metabolism KEGG]] moved to [[Pathway:Homo sapiens:Tryptophane Metabolism KEGG]]: Renaming species
7848view16:22, 18 December 2007MaintBotfixed category names
7407view12:42, 4 November 2007MaintBotAdded categories to GPML
6402view22:18, 22 May 2007L.M.Ferrantegpml file for [[Human:Tryptophane_Metabolism_KEGG]]

Error details

exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/a/a6/WP465_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
	at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
	at org.pathvisio.core.Engine.importPathway(Unknown Source)
	at org.pathvisio.core.util.Converter.main(Unknown Source)

<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/a/a6/WP465_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 106203)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
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