Blood clotting and drug effects (Homo sapiens)

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Causes vasoconstrictionBlood clotCauses vasodilationStimulates platelet aggregationInhibits platelet aggregationCOXNSAIDsThrombinVitamin KThromboxane A2Prostaglandin H2ProstacyclinArachidonic acidCoumadinFibrinogenThromboxane A2FibrinProthrombin


Test pathway

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Ontology Terms



  1. Glen D. Lawrence; ''The Fats of Life: Essential Fatty Acids in Health and Disease''; 978-0-8135-4677-3, 2010


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105276view21:38, 25 July 2019KhanspersModified title
105273view21:25, 25 July 2019Khanspersconverted interactions in legend to graphical lines
105234view13:36, 23 July 2019EgonwFibrinogen is a protein complex.
105094view19:02, 5 July 2019AlexanderPicoModified title
104812view10:40, 19 June 2019ChrisAdded legend
104497view10:47, 29 May 2019Chris-Improved visuals of the pathway

- Added annotations

- Fixed text labels
104447view13:19, 27 May 2019ChrisModified title
104446view12:57, 27 May 2019ChrisModified description
104240view21:31, 10 May 2019KhanspersModified description
104059view07:03, 30 April 2019EgonwReplaced secondary ChEBI IDs with primary IDs.
104056view13:21, 29 April 2019DeSlOntology Term : 'coagulation cascade pathway' added !
104055view13:15, 29 April 2019ChrisNew pathway

External references


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NameTypeDatabase referenceComment
Arachidonic acidMetaboliteCHEBI:2799 (ChEBI)
COXProteinQ410251 (Wikidata)
CoumadinMetaboliteCHEBI:10034 (ChEBI)
FibrinMetaboliteCHEBI:5054 (ChEBI)
FibrinogenMetaboliteQ381899 (Wikidata)
NSAIDsMetaboliteCHEBI:35475 (ChEBI)
ProstacyclinMetaboliteCHEBI:245 (ChEBI)
Prostaglandin H2MetaboliteCHEBI:8520 (ChEBI)
ProthrombinMetaboliteCHEBI:8583 (ChEBI)
ThrombinMetaboliteCHEBI:9574 (ChEBI)
Thromboxane A2Protein
Thromboxane A2MetaboliteCHEBI:26995 (ChEBI)
Vitamin KMetaboliteCHEBI:10009 (ChEBI)

Annotated Interactions

No annotated interactions

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