Vitamin B6-dependent and responsive disorders (Homo sapiens)

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piperideine-2-carboxylatealpha aminoadipic acidglutamic semialdehydesPipecolic acidSaccharopinepyridoxamine-pPyridoxal-PpyridoxalL-~'piperideine-6-carboxylatePyridoxineL-prolinePyridoxine-PDehydrogenasedeficiencypyridoxaminealpha aminoadipic semialdehyde2-keto 6-amino caproic acidL-lysineglutamic acidPyridoxal-PPyridoxal-Ppyridoxalpyridoxamine-pPyridoxine-Ppyridoxaminepyridoxamine-pPyridoxinePyridoxine-P


Description

No description

Quality Tags

Ontology Terms

 

Bibliography

  1. Blau, N., Duran, M., Gibson, K.M., Dionisi-Vici, C.; ''Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases, Chapter 11''; SBN 978-3-642-40337-8, 2014

History

View all...
CompareRevisionActionTimeUserComment
102316view13:47, 19 December 2018DeSlChanged wrong ID for glutamic semialdehyde
98922view05:18, 16 October 2018EgonwModified description
98254view09:48, 15 August 2018DeSlModified description
98252view09:45, 15 August 2018DeSlChanged disease nodes to labels, changed layout of background colour slighlty.
97294view20:25, 7 May 2018Khanspersconnected interactions
96743view06:05, 2 April 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
96735view15:03, 1 April 2018EgonwConverted interactions to regular arrows, which were not mim:conversions.
96671view15:26, 25 March 2018EgonwConverted interactions to regular arrows, which were not mim:conversions.
96570view13:23, 20 March 2018Lisaaheldadded more ID's
96569view13:08, 20 March 2018LisaaheldAdded ID's
96568view12:54, 20 March 2018LisaaheldAdded IDs
96534view21:07, 17 March 2018DeSlConnected all unconnected lines
96513view16:16, 16 March 2018DeSlOntology Term : 'neural cell' added !
96512view16:13, 16 March 2018DeSlOntology Term : 'hyperprolinemia type II disease pathway' added !
96511view16:12, 16 March 2018DeSlOntology Term : 'hypophosphatasia disease pathway' added !
96510view16:12, 16 March 2018DeSlOntology Term : 'infantile hypophosphatasia' added !
96509view16:12, 16 March 2018DeSlOntology Term : 'childhood hypophosphatasia' added !
96508view16:11, 16 March 2018DeSlOntology Term : 'hypophosphatasia' added !
96507view16:11, 16 March 2018DeSlOntology Term : 'lysine degradation pathway' added !
96506view16:10, 16 March 2018DeSlOntology Term : 'vitamin B6 metabolic pathway' added !
96505view16:08, 16 March 2018DeSladded last 2 diseases, changed layout a bit more.
96504view15:38, 16 March 2018DeSlModified description
96503view15:37, 16 March 2018DeSlAdded OMIM IDs for diseases, removed BIND IDs for conversions which were not needed.
96502view15:35, 16 March 2018DeSlModified description
96501view15:25, 16 March 2018DeSlMade various layout changes, added more metabolites+enzymes, changed wrong IDs
96486view16:45, 15 March 2018LisaaheldAddes ASA
96475view16:06, 15 March 2018Lisaaheldmade P5C and P6C red and gave name
96292view15:50, 7 March 2018LisaaheldNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2-keto 6-amino caproic acidMetabolite
Dehydrogenase deficiencyP5C
L-lysineMetaboliteCHEBI:18019 (ChEBI)
L-prolineMetaboliteCHEBI:17203 (ChEBI)
L-~'piperideine-6-carboxylateP6C
Pipecolic acidMetaboliteCHEBI:6284 (ChEBI)
Pyridoxal-PMetaboliteCHEBI:18405 (ChEBI)
Pyridoxine-PMetaboliteCHEBI:28803 (ChEBI)
PyridoxineMetaboliteCHEBI:8671 (ChEBI)
SaccharopineMetaboliteCHEBI:7406 (ChEBI)
alpha aminoadipic acidMetabolite
alpha aminoadipic semialdehydeMetabolite
glutamic acidMetaboliteCHEBI:16015 (ChEBI)
glutamic semialdehydesMetaboliteCHEBI:24313 (ChEBI)
piperideine-2-carboxylateMetabolite
pyridoxalMetaboliteCHEBI:17310 (ChEBI)
pyridoxamine-pMetabolite
pyridoxamineMetaboliteCHEBI:57761 (ChEBI)

Annotated Interactions

View all...
SourceTargetTypeDatabase referenceComment
Pyridoxal-Ppyridoxalmim-modificationIntestinal alkaline phosphatases (Ensembl) Intestinal alkaline phosphatases
Pyridoxal-Ppyridoxalmim-modificationTNSAP (BIND) TNSAP
Pyridoxine-PPyridoxal-Pmim-conversionpyridoxamine 5' phosphate oxidase (BIND) pyridoxamine 5' phosphate oxidase
PyridoxinePyridoxine-Pmim-modificationPhosphate kinase (BIND) Phosphate kinase
pyridoxalPyridoxal-Pmim-modificationPhosphate kinase (BIND) Phosphate kinase
pyridoxamine-pPyridoxal-Pmim-conversionpyridoxamine 5' phosphate oxidase (BIND) pyridoxamine 5' phosphate oxidase
pyridoxamine-ppyridoxaminemim-modificationIntestinal alkaline phosphatases (Ensembl) Intestinal alkaline phosphatases
pyridoxaminepyridoxamine-pmim-modificationPhosphate kinase (BIND) Phosphate kinase
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