Phosphodiesterases in neuronal function (Homo sapiens)
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Description
Phosphodiesterases are enzymes which break phosphodiester bonds and play an importan role in signaling pathways, especially in second messenger pathways which involve cyclic AMP or GMP.
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Bibliography
- Heckman PR, van Duinen MA, Bollen EP, Nishi A, Wennogle LP, Blokland A, Prickaerts J; ''''; , PubMed Europe PMC
- Kitabchi AE, Wilson DB, Sharma RK.; ''Steroidogenesis in isolated adrenal cells of rat. II. Effect of caffeine on ACTH and cyclic nucleotide-induced steroidogenesis and its relation to cyclic nucleotide phosphodiesterase (PDE).''; vBiochem Biophys Res Commun. , 1971 PubMed Europe PMC
- Minami N, Suzuki Y, Yamamoto M, Kihira H, Imai E, Wada H, Kimura Y, Ikeda Y, Shiku H, Nishikawa M.; ''Inhibition of shear stress-induced platelet aggregation by cilostazol, a specific inhibitor of cGMP-inhibited phosphodiesterase, in vitro and ex vivo.''; Life Sci. , 1997 PubMed Europe PMC
- Khairallah M, Khairallah RJ, Young ME, Allen BG, Gillis MA, Danialou G, Deschepper CF, Petrof BJ, Des Rosiers C.; ''Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency.''; Proc Natl Acad Sci U S A., 2008 PubMed Europe PMC
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