NO/cGMP/PKG mediated Neuroprotection (Homo sapiens)

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NeuronA Subunits B SubunitsCNG Cation ChannelsMitochondrionNR2 SubunitsEndothelial CellMitochondrialPermeabilityTransitionPoreNatriuretric PeptidesNMDAR: Ligand ComplexSmall SolublesNR1 SubunitCalmodulinNF-kBsGCNucleusMicrogliaCAMK IINR1 Interacting ProteinsNMDA ReceptorCell DepolarizationCREB1PDE3NFKB1GUCY1A2AMPNPR1GRIN2CGUCY1B3PDE2eNOSK+cGMPCAMK2DAKAP9GRIN2DGRIN1GRIN2BNADPHApoptosisMg2+NADPBNPPKG2CNGA1CNGA3CNGB3TNF-aCa2+GUCY1B2GTPiNOSBCL2IFN-GammaTBHDLG4CAMK2GL-CitrullineCAMK2ANOCALM1XIAPACTN2O2L-ArginineCNGB1GUCY1A3GRIN2ANFKBIAIL-1BTSPOCASP9Ca2+cAMPL-GlutamateCNGA4Cytochrome CCAMK2BLPSCNGA2Ca2+NFKB3ANPnNOSCyclophilin DNEFLCaspase CascadeO2L-ArginineNADPHTBHNADPL-CitrullineNOACTN2DLG4NR2 Interacting ProteinsCalmodulinCa2+CALM1O2L-ArginineNADPHTBHNADPL-CitrullineNONOSmall SolublesK+Ca2+BADSmall SolublesK+Ca2+Small SolublesK+Ca2+Mitochondrial DepolarizationCytochrome C


Description

NO/cGMP/PKG Neuroprotection

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
107157view14:24, 17 September 2019MaintBotChEBI identifier normalization
106656view21:17, 12 September 2019KhanspersModified description
105657view05:15, 10 August 2019KhanspersModified description
96448view09:26, 15 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
96378view06:46, 11 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
92677view11:02, 28 June 2017SauerThorbenOntology Term : 'signaling pathway involving second messengers' added !
92676view11:01, 28 June 2017SauerThorbenOntology Term : 'signaling pathway' added !
92675view11:01, 28 June 2017SauerThorbenOntology Term : 'neuron' added !
92674view11:01, 28 June 2017SauerThorbenOntology Term : 'neural cell' added !
92673view11:01, 28 June 2017SauerThorbenOntology Term : 'dementia' added !
92672view09:59, 28 June 2017SauerThorbenModified title
92671view09:57, 28 June 2017SauerThorbenNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACTN2GeneProductENSG00000077522 (Ensembl)
AKAP9GeneProductENSG00000127914 (Ensembl)
AMPMetaboliteCHEBI:2356 (ChEBI)
ANPGeneProductENSG00000175206 (Ensembl)
Apoptosis
BADGeneProductENSG00000002330 (Ensembl)
BCL2GeneProductENSG00000171791 (Ensembl)
BNP GeneProductENSG00000120937 (Ensembl)
CALM1GeneProductENSG00000198668 (Ensembl)
CAMK2AGeneProductENSG00000070808 (Ensembl)
CAMK2BGeneProductENSG00000058404 (Ensembl)
CAMK2DGeneProductENSG00000145349 (Ensembl)
CAMK2GGeneProductENSG00000148660 (Ensembl)
CASP9GeneProductENSG00000132906 (Ensembl)
CNGA1GeneProductENSG00000198515 (Ensembl)
CNGA2GeneProductENSG00000183862 (Ensembl)
CNGA3GeneProductENSG00000144191 (Ensembl)
CNGA4GeneProductENSG00000132259 (Ensembl)
CNGB1GeneProductENSG00000070729 (Ensembl)
CNGB3GeneProductENSG00000170289 (Ensembl)
CREB1GeneProductENSG00000118260 (Ensembl)
Ca2+MetaboliteCHEBI:3308 (ChEBI)
Caspase Cascade
Cyclophilin DGeneProductENSG00000171497 (Ensembl)
Cytochrome CGeneProductENSG00000172115 (Ensembl)
DLG4GeneProductENSG00000132535 (Ensembl)
GRIN1GeneProductENSG00000176884 (Ensembl)
GRIN2AGeneProductENSG00000183454 (Ensembl)
GRIN2BGeneProductENSG00000273079 (Ensembl)
GRIN2CGeneProductENSG00000161509 (Ensembl)
GRIN2D GeneProductENSG00000105464 (Ensembl)
GTPMetaboliteCHEBI:37565 (ChEBI)
GUCY1A2GeneProductENSG00000152402 (Ensembl)
GUCY1A3GeneProductENSG00000164116 (Ensembl)
GUCY1B2GeneProductENSG00000123201 (Ensembl)
GUCY1B3GeneProductENSG00000061918 (Ensembl)
IFN-GammaProteinENSG00000111537 (Ensembl)
IL-1BProteinENSG00000125538 (Ensembl)
K+MetaboliteCHEBI:29103 (ChEBI)
L-ArginineMetabolite16467 (ChEBI)
L-CitrullineMetabolite16349 (ChEBI)
L-GlutamateMetaboliteCHEBI:16015 (ChEBI)
LPS89981 (ChEBI)
Mg2+MetaboliteCHEBI:6635 (ChEBI)
NADP Metabolite18009 (ChEBI)
NADPHMetabolite16474 (ChEBI)
NEFLGeneProductENSG00000277586 (Ensembl)
NFKB1GeneProductENSG00000109320 (Ensembl)
NFKB3GeneProductENSG00000173039 (Ensembl)
NFKBIAGeneProductENSG00000100906 (Ensembl)
NOMetabolite16480 (ChEBI)
NPR1GeneProductENSG00000169418 (Ensembl)
O2Metabolite29372 (ChEBI)
PDE2GeneProductENSG00000186642 (Ensembl)
PDE3GeneProductENSG00000172572 (Ensembl)
PKG2GeneProductENSG00000138669 (Ensembl)
TBHMetabolite64090 (ChEBI)
TNF-a ProteinENSG00000232810 (Ensembl)
TSPOGeneProductENSG00000100300 (Ensembl)
XIAPGeneProductENSG00000101966 (Ensembl)
cAMPMetaboliteCHEBI:1325 (ChEBI)
cGMPMetaboliteCHEBI:1327 (ChEBI)
eNOSGeneProductENSG00000164867 (Ensembl)
iNOSGeneProductENSG00000007171 (Ensembl)
nNOSGeneProductENSG00000089250 (Ensembl)

Annotated Interactions

No annotated interactions

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