Interleukin-4 belongs to the IL-2 family of cytokines, which includes IL-2, IL-7, IL-9, IL-15 and IL-21. It signals through 2 different receptor complexes; Receptor complex 1 comprises of IL-4 receptor alpha (IL4RA) and the common gamma chain (γc), Receptor complex 2 comprises of IL4RA and IL-13 receptor alpha1. IL-4 stimulates the JAK/STAT and MAPK signaling modules.
Source: NetPath http://www.netpath.org/pathways?path_id=NetPath_16
NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
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