One carbon metabolism and related pathways (Homo sapiens)

Name: WikiPathways
License: https://creativecommons.org/publicdomain/zero/1.0/

From WikiPathways

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Description

No description

Comments

HomologyMapper: This pathway was inferred from Mus musculus pathway "One carbon metabolism and related pathways", WP1770 revision 78414, with a 100.0% conversion rate.

Quality Tags

Ontology Terms

Bibliography

''''; https://www.genome.jp/dbget-bin/www_bget?pathway+mmu00270,

History

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Revision	Action	Time	User	Comment
107153	view	14:23, 17 September 2019	MaintBot	ChEBI identifier normalization
106513	view	21:00, 5 September 2019	Khanspers	connected interactions
106512	view	20:55, 5 September 2019	Khanspers	Modified description
106511	view	20:54, 5 September 2019	Khanspers	added reference
106213	view	12:10, 16 August 2019	MaintBot	HMDB identifier normalization
105765	view	19:36, 15 August 2019	Khanspers	Modified description
105764	view	19:34, 15 August 2019	Khanspers	Modified description
102896	view	10:25, 27 January 2019	Egonw	Replaced two PubChem SID with CID identifiers.
96353	view	17:03, 9 March 2018	Egonw	Converted interactions to regular arrows, which were not mim:conversions.
96327	view	09:30, 8 March 2018	Mkutmon	Updated homology conversion
96235	view	13:30, 1 March 2018	DeSl	Modified description
96234	view	13:30, 1 March 2018	DeSl	Removed licence number and last modified part.
94312	view	12:05, 1 September 2017	Marvin M2	Connected unconnected lines
94206	view	21:13, 25 August 2017	DeSl	Added ID for phosphocholine
93078	view	09:01, 28 July 2017	Elisa	Fixed unconnected interactions (added anchors to lines)
93018	view	09:37, 25 July 2017	DeSl	Added small sidebrach from L-Cystationine to Ophthalmate.
91096	view	01:13, 4 January 2017	Khanspers	connected interactions
90808	view	18:21, 14 December 2016	Khanspers	Ontology Term : 'folate mediated one-carbon metabolic pathway' added !
90807	view	18:20, 14 December 2016	Khanspers	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
(S)-2-Aminobutanoate	Metabolite	CHEBI:35619 (ChEBI)
10-formyldihydrofolate	Metabolite	HMDB06485 (HMDB)
2-oxobutanoate	Metabolite	16763 (ChEBI)
3-Sulfinoalanine	Metabolite	C00606 (KEGG Compound)
5,10-Methenyltetrahydrofolic acid	Metabolite	C00445 (KEGG Compound)
5-Methyltetrahydrofolic acid	Metabolite	C00440 (KEGG Compound)
5-oxoproline	Metabolite	C01879 (KEGG Compound)
AGXT2	GeneProduct	ENSG00000113492 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12660
AHCYL1	GeneProduct	ENSG00000168710 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:229709
BAAT	GeneProduct	ENSG00000136881 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12012
BCAT1	GeneProduct	ENSG00000060982 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12651
BHMT2	GeneProduct	ENSG00000132840 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64918
BHMT	GeneProduct	ENSG00000145692 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12116
Betaine	Metabolite	C00719 (KEGG Compound)
CBS	GeneProduct	ENSG00000160200 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12411
CDO1	GeneProduct	ENSG00000129596 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12583
CDP-Ethanolamine	Metabolite	C00570 (KEGG Compound)
CDP-choline	Metabolite	C00307 (KEGG Compound)
CEPT1	GeneProduct	ENSG00000134255 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:99712
CHDH	GeneProduct	ENSG00000016391 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:218865
CHKA	GeneProduct	ENSG00000110721 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12660
CHKB	GeneProduct	ENSG00000100288 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12651
CHPT1	GeneProduct	ENSG00000111666 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:212862
CSAD	GeneProduct	ENSG00000139631 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:246277
CTH	GeneProduct	ENSG00000116761 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:107869
Choline	Metabolite	C00114 (KEGG Compound)
DHFR2	GeneProduct	ENSG00000178700 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13361
DMGDH	GeneProduct	ENSG00000132837 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74129
DNM1	GeneProduct	ENSG00000106976 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13429
DNMT3A	GeneProduct	ENSG00000119772 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13435
Dimethylglycine	Metabolite	C01026 (KEGG Compound)
ETNK1	GeneProduct	ENSG00000139163 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75320
ETNK2	GeneProduct	ENSG00000143845 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:214253
Ethanolamine	Metabolite	C00189 (KEGG Compound)
Folic acid	Metabolite	C00504 (KEGG Compound)
GAD1	GeneProduct	ENSG00000128683 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14415
GAD2	GeneProduct	ENSG00000136750 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14417
GCLC	GeneProduct	ENSG00000001084 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22171
GCLM	GeneProduct	ENSG00000023909 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14630
GNMT	GeneProduct	ENSG00000124713 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14711
GPX1	GeneProduct	ENSG00000233276 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14775
GPX2	GeneProduct	ENSG00000176153 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14776
GPX3	GeneProduct	ENSG00000211445 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14778
GPX4	GeneProduct	ENSG00000167468 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:625249
GPX5	GeneProduct	ENSG00000224586 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14780
GPX6	GeneProduct	ENSG00000198704 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75512
GPX7	GeneProduct	ENSG00000116157 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67305
GSR	GeneProduct	ENSG00000104687 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14782
GSS	GeneProduct	ENSG00000100983 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22171
Glutamate	Metabolite	C00217 (KEGG Compound)
Glutathione (GSH)	Metabolite	C00051 (KEGG Compound)
Glutathione disulfide (GSSG)	Metabolite	C00127 (KEGG Compound)
Glycine	Metabolite	C00037 (KEGG Compound)
Homocysteine	Metabolite	C05330 (KEGG Compound)
Hypotaurine	Metabolite	C00519 (KEGG Compound)
L-Cystathionine	Metabolite	C02291 (KEGG Compound)
L-Cysteine	Metabolite	C00097 (KEGG Compound)
L-Methionine	Metabolite	HMDB00696 (HMDB)
L-Serine	Metabolite	C00065 (KEGG Compound)
MAT1A	GeneProduct	ENSG00000151224 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11720
MAT2A	GeneProduct	ENSG00000168906 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:232087
MTHFR	GeneProduct	ENSG00000177000 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17769
MTR	GeneProduct	ENSG00000116984 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:238505
NADP	Metabolite	C00006 (KEGG Compound)
NADPH	Metabolite	C00005 (KEGG Compound)
O-Phosphoethanolamine	Metabolite	C00346 (KEGG Compound)
Ophthalmate	Metabolite	254741470 (PubChem-substance)
PCYT1A	GeneProduct	ENSG00000161217 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13026
PCYT1B	GeneProduct	ENSG00000102230 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:236899
PCYT2	GeneProduct	ENSG00000185813 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:68671
PEMT	GeneProduct	ENSG00000133027 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18618
PLD1	GeneProduct	ENSG00000075651 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18805
Phosphatidylcholines	Metabolite	8002-43-5 (CAS)
Phosphatidylethanolamine	Metabolite	C00350 (KEGG Compound)
Phosphocholine	Metabolite	CHEBI:18132 (ChEBI)
S-Adenosylhomocysteine	Metabolite	C00021 (KEGG Compound)
S-Adenosylmethionine	Metabolite	C00019 (KEGG Compound)
SARDH	GeneProduct	ENSG00000123453 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:192166
SHMT1	GeneProduct	ENSG00000176974 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20425
SHMT2	GeneProduct	ENSG00000182199 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:108037
SOD1	GeneProduct	ENSG00000142168 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20655
SOD2	GeneProduct	ENSG00000112096 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20656
SOD3	GeneProduct	ENSG00000109610 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20657
Sarcosine	Metabolite	C00213 (KEGG Compound)
TYMS	GeneProduct	ENSG00000176890 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22171
Taurine	Metabolite	C00245 (KEGG Compound)
Taurochenodesoxycholic acid	Metabolite	C05465 (KEGG Compound)
Taurocholic acid	Metabolite	C05122 (KEGG Compound)
Tetrahydrofolic acid	Metabolite	C00101 (KEGG Compound)
Total Phospholipids	Metabolite	16247 (ChEBI)
gamma-Glutamylcysteine	Metabolite	C00669 (KEGG Compound)
gamma-L-Glutamyl-L-2-aminobutyrate	Metabolite	254741469 (PubChem-substance)

Annotated Interactions

No annotated interactions

One carbon metabolism and related pathways (Homo sapiens)

From WikiPathways

Description

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