Wnt Signaling Pathway (Homo sapiens)

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452, 524502340, 442462, 524280, 443382, 506215, 314, 34052445263, 340649, 13, 26, 183, 191...13, 191, 270, 300, 417262, 52449, 234, 42250, 129FrizzledreleasePIP2WntCaDestruction complex2+MTORDVL1CSNK1DDVL2CSNK1EMAPK2CSNK1G1CCND1RAC1CCND1TSC1CTNNB1PRKCGPRKCBPRKCANFATC2MAP3K7AXIN1CDK6CTBP1PI4K2AAPCGJA1TCF7L2CSNK1A1GCKRGSK3ADVL1RYKCTNNB1RHOAROR1FRAT1LRP5AXIN2MYCSOX1PPARGAKT1LRP6TCF3ARRB2BCL9TEKTCF4LEF1LRP6PIP5K1BDVL3PP364, 524245, 52424574, 237282, 411102, 141, 182, 188, 197...GSK3BROR289MAPK9MAPK8502, 544, 553117, 524307, 309MAP3K7P33691, 505505TSC2356, 524524, 531192, 282, 411, 440, 480565266NLKEnzyme complexInhibitionAuto catalysisTransportPositive regulation of gene expressionLeads to through unknown mechanismNegative regulation of gene expressionTranslocation UbiquitinationDeubiquitinationSumoylationInduced catalysisProtein-protein interactionAcetylationDephosphorylationLEGENDPhosphorylationProteinmRNAProteinReceptorLigandDeacetylationGolgi apparatusEndosomeNucleusMitochondrionDesumoylationMethylationDemethylationPalmitoylationCytoplasmECPlasma membraneMTEndoplasmic reticulumCYPMGONUExtracellularERENProteolytic cleavageWnt Signaling PathwayCYNUCYNU


Description

No description

Quality Tags

Ontology Terms

 

Bibliography

  1. Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, Goel R, Jacob HK, Zhong J, Sekhar R, Nanjappa V, Balakrishnan L, Subbaiah R, Ramachandra YL, Rahiman BA, Prasad TS, Lin JX, Houtman JC, Desiderio S, Renauld JC, Constantinescu SN, Ohara O, Hirano T, Kubo M, Singh S, Khatri P, Draghici S, Bader GD, Sander C, Leonard WJ, Pandey A; ''''; , PubMed

History

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CompareRevisionActionTimeUserComment
97637view13:39, 31 May 2018Lorasimonsconnect line
97562view07:24, 25 May 2018Fehrhartadded citation
97561view07:22, 25 May 2018Fehrhartfixed lines
94887view18:04, 11 October 2017KhanspersModified title
78571view14:50, 7 January 2015MaintBotadded missing graphIds
70630view00:23, 20 August 2013MaintBotUpdated xrefs by Anatoly Urisman
70108view19:00, 12 July 2013MaintBotupdated to 2013 schema
68007view06:28, 29 June 2013EgonwAdded missing "Entrez Gene" data sources to Proteins with an identifier (ID confirmed via Entrez Gene)
67750view11:58, 26 June 2013DdiglesOntology Term : 'canonical Wnt signaling pathway' added !
62949view11:52, 5 May 2013MaintBotModified title
47977view14:34, 23 April 2012NetPathModified description
47854view17:27, 13 April 2012Sham.ukPeriodical save, work in progress
47851view17:17, 13 April 2012Sham.ukPeriodical save, work in progress
47850view17:07, 13 April 2012Sham.ukPeriodical save, work in progress
47849view16:57, 13 April 2012Sham.ukPeriodical save, work in progress
45009view17:40, 6 October 2011KhanspersOntology Term : 'Wnt signaling pathway' added !
44607view21:23, 21 September 2011KhanspersUpdating content to NetSlim
44606view21:22, 21 September 2011KhanspersUpdating content to NetSlim
44605view21:21, 21 September 2011KhanspersUpdating content to NetSlim
44121view20:51, 24 August 2011KhanspersReverted to version '23:40, 1 March 2011' by Khanspers
44016view22:39, 22 August 2011Khanspers
44010view22:11, 22 August 2011KhanspersModified description
44005view21:51, 22 August 2011KhanspersAdded category
44004view21:47, 22 August 2011KhanspersModified description
44003view21:40, 22 August 2011KhanspersModified description
44002view21:38, 22 August 2011Khanspersremoved GenMAPP comment
44001view21:37, 22 August 2011KhanspersModified description
44000view21:30, 22 August 2011KhanspersUpdating pathway from NetSlim
41151view23:40, 1 March 2011MaintBotRemoved redundant pathway information and comments
38067view20:10, 6 August 2010AlexanderPicoadded wnt9b and connected to database
38019view02:40, 30 July 2010ElgavishReverted to version '02:33, 30 July 2010' by Elgavish
38018view02:39, 30 July 2010ElgavishSpecify description
38017view02:33, 30 July 2010ElgavishPCP pathway
38016view02:27, 30 July 2010ElgavishPeriodical save, work in progress
35029view09:17, 11 February 2010Thomasremoved old genmapp comments (moved to description)
35021view09:11, 11 February 2010ThomasModified description
28127view19:35, 27 January 2009KhanspersReverted to version '13:36, 14 November 2008' by Khanspers
28125view19:12, 27 January 2009KhanspersRemoved Netpath suffix from name
22584view13:36, 14 November 2008Thomaschanged title (was duplicate of WP428)
21439view11:31, 14 November 2008MaintBot[[Pathway:Homo sapiens:Wnt NetPath 8]] moved to [[Pathway:WP363]]: Moved to stable identifier
14174view22:56, 21 May 2008AlexanderPicoModified categories
11945view23:29, 12 May 2008KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct207
APCGeneProduct324
ARRB2GeneProduct409
AXIN1GeneProduct8312
AXIN2GeneProduct8313 (Entrez Gene)
BCL9GeneProduct607
CCND1GeneProduct595
CCND1GeneProduct595 (Entrez Gene)
CDK6GeneProduct1021
CSNK1A1GeneProduct1452
CSNK1DGeneProduct1453
CSNK1EGeneProduct1454
CSNK1G1GeneProduct53944
CTBP1GeneProduct1487
CTNNB1GeneProduct1499
DVL1GeneProduct1855
DVL2GeneProduct1856
DVL3GeneProduct1857
FRAT1GeneProduct10023
GCKRGeneProduct2646
GJA1GeneProduct2697 (Entrez Gene)
GSK3AGeneProduct2931
GSK3BGeneProduct2932
LEF1GeneProduct51176
LRP5GeneProduct4041
LRP6GeneProduct4040
LigandGeneProduct7040 (Entrez Gene)
MAP3K7GeneProduct6885 (Entrez Gene)
MAPK2GeneProduct2011 (Entrez Gene)
MAPK8GeneProduct5599
MAPK9GeneProduct5600
MTORGeneProduct207 (Entrez Gene)
MYCGeneProduct4609 (Entrez Gene)
NFATC2GeneProduct4773
NLKGeneProduct51701
PI4K2AGeneProduct55361 (Entrez Gene)
PIP5K1BGeneProduct8395
PPARGGeneProduct5468
PRKCAGeneProduct5578
PRKCBGeneProduct5579
PRKCGGeneProduct5582
ProteinProtein5894 (Entrez Gene)
ProteinProtein
RAC1GeneProduct5879
RHOAGeneProduct387
ROR1GeneProduct4919
ROR2GeneProduct4920
RYKGeneProduct6259
ReceptorGeneProduct7040 (Entrez Gene)
SOX1GeneProduct6656
TCF3GeneProduct6929
TCF4GeneProduct6934
TCF7L2GeneProduct6934
TEKGeneProduct7010 (Entrez Gene)
TSC1GeneProduct7248 (Entrez Gene)
TSC2GeneProduct7249
mRNAProtein

Annotated Interactions

No annotated interactions

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