Evolocumab Mechanism (Homo sapiens)

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(Ontology Term : 'altered cholesterol biosynthetic pathway' added !)
Current revision (13:06, 8 July 2019) (view source)
(Ontology Term : 'hepatocyte' added !)
 
Line 192: Line 192:
       <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dorey, Emma</bp:AUTHORS>
       <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dorey, Emma</bp:AUTHORS>
     </bp:PublicationXref>
     </bp:PublicationXref>
-
   <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>drug pathway</bp:TERM><bp:ID>PW:0000754</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary><bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>altered cholesterol transport pathway</bp:TERM><bp:ID>PW:0001347</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary><bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>altered cholesterol biosynthetic pathway</bp:TERM><bp:ID>PW:0000752</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary></Biopax>
+
   <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>drug pathway</bp:TERM><bp:ID>PW:0000754</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary><bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>altered cholesterol transport pathway</bp:TERM><bp:ID>PW:0001347</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary><bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>altered cholesterol biosynthetic pathway</bp:TERM><bp:ID>PW:0000752</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary><bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>hepatocyte</bp:TERM><bp:ID>CL:0000182</bp:ID><bp:Ontology>Cell Type</bp:Ontology></bp:openControlledVocabulary></Biopax>
</Pathway>
</Pathway>

Current revision

Error rendering pathway page

This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.

Pathway history

View all...
CompareRevisionActionTimeUserComment
105111view13:06, 8 July 2019DeSlOntology Term : 'hepatocyte' added !
105110view13:05, 8 July 2019DeSlOntology Term : 'altered cholesterol biosynthetic pathway' added !
105109view13:05, 8 July 2019DeSlOntology Term : 'altered cholesterol transport pathway' added !
105108view12:55, 8 July 2019DeSlConverted DataNode type for Evolocumab from protein to metabolite.
88049view13:44, 25 July 2016SusanOntology Term : 'drug pathway' added !
81714view18:08, 25 August 2015MaintBotfixed typo in lit ref
81680view09:59, 23 August 2015EgonwAdded an xref for Evolocumab (which links to at least a CAS registry number).
81671view22:33, 22 August 2015AlexanderPicofixing multiline label
81670view22:32, 22 August 2015AlexanderPicofixing multiline label
81669view22:24, 22 August 2015AlexanderPicoQuick edit to datanode annotation or property
81668view22:22, 22 August 2015AlexanderPicoAdded lit ref
81667view22:13, 22 August 2015AlexanderPicoModified description
81666view22:05, 22 August 2015AlexanderPicoNew pathway

Error details

exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/f/f2/WP3408_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
	at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
	at org.pathvisio.core.Engine.importPathway(Unknown Source)
	at org.pathvisio.core.util.Converter.main(Unknown Source)

<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/f/f2/WP3408_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 105111)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
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