Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Homo sapiens)

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2, 8, 12121212212, 14212212, 148, 128, 12nucleoplasmcytosolTEST HIST1H2AJ HIST1H2BD O2H2AFX p-T12,MeK-10-HIST1H3A p-T774-PKN1 p-T774-PKN1 H2BFS HIST1H2AD HIST1H2AC H2AFZ HIST1H2BC p-T12,MeK-HIST2H3A HIST1H2AB 2OGHIST1H2BH AR CH2Op-T12, Me2K-10-HIST2H3A HIST1H4 6-Dehydrotestosterone HIST1H2BO HIST1H2BM p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4CAR O2KLK2 Gene 6-Dehydrotestosterone HIST2H2AC AR H2AFZ HIST1H2BL HIST1H2AB TEST TEST CO2HIST3H2BB HIST1H2BM HIST1H2BC HIST1H2AD H2AFB1 AR HIST3H2BB KLK3 TEST p-T774-PKN1 HIST1H2BJ HIST1H2BA NCOA2HIST1H2AC KLK2 Gene p-T12, Me2K-10-HIST1H3A HIST2H2AA3 KDM1A HIST1H2BK p-T774-PKN1 HIST1H2BN HIST1H2BL KDM4CHIST2H2BE H2BFS H2AFZ H2AFX HIST1H2AD H2AFB1 AR p-T774-PKN1 DHTEST HIST1H2BB HIST1H4 DHTEST HIST3H2BB HIST2H2BE HIST1H2BB KLK2 Gene HIST1H2AC p-T12-HIST1H3A H2BFS HIST2H2AC KDM1A p-T774-PKN1:AR:Androgen6-Dehydrotestosterone HIST1H2AC HIST1H2BJ AR H2AFZ HIST1H2AB CO2p-T12, Me3K-10-HIST1H3A HIST1H2BJ H2BFS KLK2 Gene HIST1H2BD HIST1H2BH HIST1H2BD HIST1H2AB KLK3 Gene HIST1H4 2OGHIST1H2BK DHTEST HIST1H4 HIST1H4 HIST1H2BK androst-4-en-3,17-dione KLK2,3 genesHIST1H2BN H2AFX androst-4-en-3,17-dione p-T774-PKN1 KLK2 Gene HIST1H2AB NCOA2 HIST1H4 HIST2H2AA3 HIST1H2BD H2AFX KLK2 Gene HIST1H2BO H2AFX HIST1H2BN HIST1H2BJ HIST2H2AC KLK2 Gene HIST1H2BB HIST1H2BD Me3K-10-HIST2H3A HIST1H2AC HIST3H2BB p-T12,Me3K-10-H3F3A p-T774-PKN1 HIST1H2BH HIST1H2AJ KLK3 Gene HIST1H2BH 6-Dehydrotestosterone H2AFB1 HIST2H2AA3 HIST1H2BA CH2OHIST1H2AB HIST1H2BO HIST2H2AA3 SUCCAHIST1H2BB HIST2H2AA3 HIST1H2BL HIST1H2AJ p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1AH2AFB1 HIST2H2BE H2AFZ HIST2H2AC KLK3 Gene HIST1H2BO DHTEST ADPp-T12-HIST2H3A HIST2H2AA3 HIST1H2AJ H2AFZ HIST1H2BL CH2Op-T12, Me3K-10-HIST1H3A Me3K-10-HIST1H3A p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3HIST1H2BA HIST3H2BB HIST1H2BA androst-4-en-3,17-dione HIST1H2AJ p-T12, Me2K-10-H3F3A HIST1H2BN p-T12, Me3K-10-HIST2H3A androst-4-en-3,17-dione HIST1H2BK p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3androst-4-en-3,17-dione HIST1H2BK TEST HIST1H2BA HIST1H2BN DHTEST DHTEST HIST1H2BO H2AFB1 HIST1H2BM androst-4-en-3,17-dione HIST2H2AA3 HIST3H2BB KLK3 Gene HIST1H2BC p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3Me3K-10-H3F3A p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A6-Dehydrotestosterone KLK3 Gene TEST HIST1H2AB AR CO2TEST HIST1H2BL H2AFX H2AFB1 O2HIST1H2BK HIST1H2BA H2AFX androst-4-en-3,17-dione HIST1H2BB androst-4-en-3,17-dione AR:AndrogenHIST2H2AC HIST1H2BJ HIST1H2BC p-T12, Me2K-10-H3F3A HIST1H2AC HIST1H2BA KDM4C HIST1H2BD HIST1H2BB SUCCAHIST1H2BM H2BFS HIST1H2AD RHO GTPases activatePKNsandrost-4-en-3,17-dione HIST1H2BJ TEST HIST1H2BL SUCCAHIST1H2BN HIST1H2BH HIST1H4 HIST1H2BM HIST1H2BC 2OGDHTEST AR HIST1H2BM H2AFZ HIST2H2BE HIST1H2BK HIST1H2BH Me3K-10-H3F3A TEST HIST1H2BH Me3K-10-HIST2H3A HIST2H2BE HIST3H2BB 6-Dehydrotestosterone TEST ATPp-T12-H3F3A 6-Dehydrotestosterone p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3p-T12, Me2K-10-HIST2H3A KLK3 Gene p-T774-PKN1 HIST1H4 KLK2,3Gene:Nucleosomewith Me3K-10-H3HIST1H2BO HIST1H2AB AR 6-Dehydrotestosterone HIST1H2BD HIST1H2AC p-T12,Me3K-10-H3F3A p-T12, Me2K-10-HIST1H3A HIST1H2BL HIST1H2BJ 6-Dehydrotestosterone p-T774-PKN1 HIST2H2AC HIST2H2BE HIST1H2AJ HIST1H2BN Me3K-10-HIST1H3A H2AFB1 6-Dehydrotestosterone KLK2 Gene AR H2BFS HIST2H2BE HIST1H2BD androst-4-en-3,17-dione HIST1H2BC HIST1H2BO HIST1H2BH p-T774-PKN1 HIST3H2BB TEST HIST1H2BC KLK3 Gene HIST1H2BC H2BFS androst-4-en-3,17-dione H2AFB1 HIST1H2BN DHTEST HIST1H2BO HIST1H2AD p-T774-PKN1:AR:Androgen:NCOA2H2AFX HIST1H2BB KLK3 Gene HIST1H2BA HIST1H2BM HIST1H2AJ HIST1H2BK p-T12,MeK-H3F3A HIST1H2BJ 6-Dehydrotestosterone H2AFZ HIST1H2AD DHTEST HIST1H2AD DHTEST HIST2H2AC KLK3 Gene p-T774-PKN1:AR:AndrogenHIST1H2AJ HIST1H2BM HIST2H2AA3 KLK2 H2BFS p-T774-PKN1AR KDM1Ap-T12, Me3K-10-HIST2H3A DHTEST HIST1H2AD KLK2 Gene HIST1H2AC HIST2H2BE HIST1H2BB HIST2H2AC KLK2,KLK3HIST1H2BL 121, 3-7, 9...121221221212212