Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Homo sapiens)

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2, 8, 1212212212, 1412, 148, 121228, 1212cytosolnucleoplasmAR HIST1H2BD HIST1H2BD 6-Dehydrotestosterone androst-4-en-3,17-dione H2BFS HIST2H2AC androst-4-en-3,17-dione androst-4-en-3,17-dione KLK2 Gene Me3K-10-H3F3A HIST1H2BL CO2p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1AH2AFX HIST3H2BB HIST1H2BH HIST2H2AA3 HIST1H2BO HIST1H2BL HIST1H2BJ KLK3 Gene HIST1H2BN HIST1H2AC HIST1H2BD H2AFZ HIST1H2BD KLK3 Gene DHTEST androst-4-en-3,17-dione p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A6-Dehydrotestosterone 2OGHIST1H2BK CH2Op-T12-HIST2H3A HIST3H2BB TEST HIST1H2BA p-T12-H3F3A p-T12-HIST1H3A HIST1H2AC 6-Dehydrotestosterone SUCCAKDM4CDHTEST HIST1H2BC HIST1H2BK TEST HIST1H2AD HIST1H2BH p-T12,Me3K-10-H3F3A H2AFX O2TEST HIST1H2AC HIST1H2BC p-T12, Me2K-10-H3F3A HIST1H2BM HIST2H2AC SUCCAHIST1H2BC AR p-T12, Me3K-10-HIST1H3A TEST HIST1H2BO androst-4-en-3,17-dione HIST1H2BO H2AFB1 KLK2 Gene HIST2H2BE H2AFB1 HIST1H2BK H2AFB1 HIST3H2BB KLK2 Gene HIST1H2BB HIST1H2BO 6-Dehydrotestosterone HIST1H2BJ HIST1H4 p-T774-PKN1 KLK2,3Gene:Nucleosomewith Me3K-10-H3HIST2H2AA3 HIST1H2BK HIST1H2BL H2BFS 6-Dehydrotestosterone p-T12, Me2K-10-HIST1H3A HIST1H2BK Me3K-10-HIST2H3A KLK2 Gene HIST1H2BJ HIST1H2AB HIST2H2BE HIST2H2AA3 DHTEST HIST1H2AB HIST1H2AJ TEST HIST1H2BB HIST1H2BB TEST HIST1H2AC DHTEST RHO GTPases activatePKNsHIST1H2AD H2BFS HIST1H4 HIST1H2AD 6-Dehydrotestosterone HIST1H2AD HIST2H2BE p-T774-PKN1 HIST1H2BO p-T12, Me2K-10-HIST2H3A 2OGAR 6-Dehydrotestosterone HIST1H2BB HIST1H2BD NCOA2 H2AFB1 KDM1A TEST p-T774-PKN1 O2HIST2H2AC HIST1H2BO androst-4-en-3,17-dione H2BFS KLK2,3 genesKLK2,KLK3H2AFZ SUCCAKDM1AHIST3H2BB HIST1H2AJ ATPH2AFB1 HIST1H2BB p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3H2BFS KLK2 Gene DHTEST H2AFX HIST1H2BB HIST2H2BE HIST1H2AJ HIST1H2BK AR Me3K-10-H3F3A HIST1H2BN HIST2H2AC H2AFX AR p-T12,MeK-10-HIST1H3A HIST1H2BM HIST1H2BH 6-Dehydrotestosterone KLK3 Gene H2BFS HIST1H4 HIST1H2BD H2AFZ CH2Op-T12,Me3K-10-H3F3A HIST1H2BB KLK3 Gene HIST3H2BB p-T774-PKN1 HIST1H2AB AR HIST1H2BC HIST1H2BM AR HIST1H2BA HIST2H2AA3 HIST1H4 TEST KLK3 Gene HIST1H2AD 6-Dehydrotestosterone KLK2 HIST1H2BH HIST1H2BA H2AFB1 HIST1H2BJ DHTEST KLK2 Gene p-T12, Me2K-10-HIST1H3A HIST1H2AB HIST2H2AC H2BFS p-T774-PKN1 AR HIST2H2BE AR H2AFZ HIST1H2BM KLK3 Gene p-T774-PKN1 HIST1H2AC p-T774-PKN1:AR:Androgenp-T12,MeK-HIST2H3A HIST1H2AC CH2OHIST1H2BA O2HIST1H2BJ HIST2H2BE HIST2H2AA3 HIST1H4 HIST1H2BD androst-4-en-3,17-dione KDM4C HIST1H2BD NCOA2DHTEST HIST3H2BB p-T774-PKN1 AR:AndrogenHIST3H2BB HIST1H2BH HIST1H2BH HIST1H2BN CO2H2AFZ androst-4-en-3,17-dione H2AFX KLK3 Gene HIST1H2AB KLK3 Gene HIST1H2BH Me3K-10-HIST2H3A p-T12,MeK-H3F3A 6-Dehydrotestosterone TEST HIST1H2BL HIST1H2BK HIST1H2AJ HIST1H2BC HIST1H2AJ DHTEST 2OGHIST3H2BB H2AFX KLK2 Gene HIST1H2AC p-T774-PKN1 H2AFZ p-T12, Me3K-10-HIST1H3A HIST1H2BC HIST1H2AD DHTEST p-T774-PKN1:AR:Androgen:NCOA2HIST1H2BO HIST1H2BL HIST1H2BO HIST1H2BH H2BFS p-T774-PKN1 p-T12, Me2K-10-HIST2H3A HIST1H2BL TEST AR p-T774-PKN1HIST1H2BM HIST1H2AB HIST1H2BL HIST1H2BN HIST2H2AC p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3HIST1H2BM HIST1H2BJ HIST1H2AJ HIST1H2BA HIST2H2AC HIST1H2BN DHTEST H2AFB1 H2AFX HIST1H2AB HIST1H2BA HIST1H2BN HIST1H2AD HIST1H4 HIST1H2BN HIST2H2AA3 HIST2H2BE HIST1H2BJ p-T774-PKN1 HIST1H2BC p-T12, Me3K-10-HIST2H3A KLK3 HIST2H2AA3 HIST2H2AC HIST1H2BA KLK2 Gene KDM1A H2AFB1 HIST1H2BM DHTEST HIST1H2BL p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3HIST1H2AJ HIST1H2BJ p-T12, Me3K-10-HIST2H3A H2AFZ CO2p-T774-PKN1:AR:AndrogenADPHIST1H2BK HIST1H4 Me3K-10-HIST1H3A HIST1H2BM HIST1H2BB KLK2 Gene 6-Dehydrotestosterone H2AFX p-T12, Me2K-10-H3F3A HIST1H2AB KLK3 Gene p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3TEST androst-4-en-3,17-dione p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4CHIST2H2AA3 HIST1H2AD HIST1H2BN HIST1H4 HIST2H2BE HIST1H2AC HIST1H2AJ HIST1H2BA AR H2AFZ Me3K-10-HIST1H3A androst-4-en-3,17-dione HIST1H2BC androst-4-en-3,17-dione 121222212121, 3-7, 9...121212