Myometrial Relaxation and Contraction Pathways (Homo sapiens)

From WikiPathways

(Difference between revisions)
Jump to: navigation, search
(HMDB identifier normalization)
(Modified description)
Line 4: Line 4:
   <Comment Source="WikiPathways-description">This pathway illustrates signaling networks implicated in uterine muscle contraction at labor and quiescence throughout gestation (pregnancy). The muscle of the uterus, responsible for contractile activity is the myometrium. Genes in this pathway are either transcribed in myometrial muscle cells or act upon the myometrium to regulate contraction. The left half of this pathway illustrates pathways of myometrial relaxation that are active throughout normal gestation. These signaling events act to suppress coordinated contractions to prevent the early onset of labor at term, largely via activation of the adenylyl-cyclase thrhough G-protein coupled receptors. On the right side of this pathway are signaling componets involved in the activation of uterine contractions at labor, in particular, activation of calcium mobilization via Oxytocin mediated binding to the Oxytocin G-protein coupled receptor. Additional genes implicated in this pathway, based on microarray expression profiling of gestation, term and postpartum of term mice are also included (e.g., Guca2b, Rdc1, Edg2) have also been included. For a detailed description of this pathway see: http://genomebiology.com/2005/6/2/R12.  
   <Comment Source="WikiPathways-description">This pathway illustrates signaling networks implicated in uterine muscle contraction at labor and quiescence throughout gestation (pregnancy). The muscle of the uterus, responsible for contractile activity is the myometrium. Genes in this pathway are either transcribed in myometrial muscle cells or act upon the myometrium to regulate contraction. The left half of this pathway illustrates pathways of myometrial relaxation that are active throughout normal gestation. These signaling events act to suppress coordinated contractions to prevent the early onset of labor at term, largely via activation of the adenylyl-cyclase thrhough G-protein coupled receptors. On the right side of this pathway are signaling componets involved in the activation of uterine contractions at labor, in particular, activation of calcium mobilization via Oxytocin mediated binding to the Oxytocin G-protein coupled receptor. Additional genes implicated in this pathway, based on microarray expression profiling of gestation, term and postpartum of term mice are also included (e.g., Guca2b, Rdc1, Edg2) have also been included. For a detailed description of this pathway see: http://genomebiology.com/2005/6/2/R12.  
-
This pathway is part the [https://assays.cancer.gov/available_assays?wp_id=WP289 CPTAC Assay Portal].</Comment>
+
 
 +
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP289 CPTAC Assay Portal]</Comment>
   <BiopaxRef>d18</BiopaxRef>
   <BiopaxRef>d18</BiopaxRef>
   <BiopaxRef>d04</BiopaxRef>
   <BiopaxRef>d04</BiopaxRef>
   <BiopaxRef>d43</BiopaxRef>
   <BiopaxRef>d43</BiopaxRef>
-
   <Graphics BoardWidth="1357.6666666666663" BoardHeight="1010.3333333333337" />
+
   <Graphics BoardWidth="1357.6666666666663" BoardHeight="1010.3333333333337"/>
   <DataNode TextLabel="RAMP1" GraphId="a0606" Type="GeneProduct" GroupRef="bcf55">
   <DataNode TextLabel="RAMP1" GraphId="a0606" Type="GeneProduct" GroupRef="bcf55">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAMP1 | receptor (calcitonin) activity modifyin..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAMP1 | receptor (calcitonin) activity modifyin..."/>
-
     <Graphics CenterX="250.33333333333331" CenterY="180.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.33333333333331" CenterY="180.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10267" />
+
     <Xref Database="Entrez Gene" ID="10267"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IGFBP6" GraphId="a107e" Type="GeneProduct">
   <DataNode TextLabel="IGFBP6" GraphId="a107e" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP6 | insulin-like growth factor binding pro..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP6 | insulin-like growth factor binding pro..."/>
-
     <Graphics CenterX="160.0" CenterY="792.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="160.0" CenterY="792.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3489" />
+
     <Xref Database="Entrez Gene" ID="3489"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG13" GraphId="a18e0" Type="GeneProduct">
   <DataNode TextLabel="GNG13" GraphId="a18e0" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG13 | guanine nucleotide binding protein (G p..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG13 | guanine nucleotide binding protein (G p..."/>
-
     <Graphics CenterX="532.6666666666666" CenterY="767.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="532.6666666666666" CenterY="767.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="51764" />
+
     <Xref Database="Entrez Gene" ID="51764"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS11" GraphId="a2e1d" Type="GeneProduct">
   <DataNode TextLabel="RGS11" GraphId="a2e1d" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS11 | regulator of G-protein signalling 11" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS11 | regulator of G-protein signalling 11"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="173.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="173.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8786" />
+
     <Xref Database="Entrez Gene" ID="8786"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCZ" GraphId="a3acd" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCZ" GraphId="a3acd" Type="GeneProduct" GroupRef="ff3b9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCZ | protein kinase C zeta" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCZ | protein kinase C zeta"/>
-
     <Graphics CenterX="1251.9999999999998" CenterY="427.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1251.9999999999998" CenterY="427.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5590" />
+
     <Xref Database="Entrez Gene" ID="5590"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY5" GraphId="a423a" Type="GeneProduct">
   <DataNode TextLabel="ADCY5" GraphId="a423a" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">There is no SwissProt entry for a full-length sequence in mouse.  This EST is from the Affymetrix Murine6500 chip.</Comment>
     <Comment Source="GenMAPP remarks">There is no SwissProt entry for a full-length sequence in mouse.  This EST is from the Affymetrix Murine6500 chip.</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY5 | adenylate cyclase 5" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY5 | adenylate cyclase 5"/>
-
     <Graphics CenterX="250.0" CenterY="772.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.0" CenterY="772.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="111" />
+
     <Xref Database="Entrez Gene" ID="111"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RYR1" GraphId="a47f7" Type="GeneProduct" GroupRef="b8909">
   <DataNode TextLabel="RYR1" GraphId="a47f7" Type="GeneProduct" GroupRef="b8909">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RYR1 | ryanodine receptor 1 (skeletal)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RYR1 | ryanodine receptor 1 (skeletal)"/>
-
     <Graphics CenterX="644.3333333333334" CenterY="432.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="644.3333333333334" CenterY="432.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6261" />
+
     <Xref Database="Entrez Gene" ID="6261"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATP2A3" GraphId="a4807" Type="GeneProduct" GroupRef="b8909">
   <DataNode TextLabel="ATP2A3" GraphId="a4807" Type="GeneProduct" GroupRef="b8909">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP2A3 | ATPase Ca++ transporting ubiquitous" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP2A3 | ATPase Ca++ transporting ubiquitous"/>
-
     <Graphics CenterX="644.3333333333334" CenterY="412.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="644.3333333333334" CenterY="412.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="489" />
+
     <Xref Database="Entrez Gene" ID="489"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATF4" GraphId="a4dce" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="ATF4" GraphId="a4dce" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF4 | activating transcription factor 4 (tax-r..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF4 | activating transcription factor 4 (tax-r..."/>
-
     <Graphics CenterX="63.0" CenterY="632.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="63.0" CenterY="632.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="468" />
+
     <Xref Database="Entrez Gene" ID="468"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GUCY2E" GraphId="a6668" Type="GeneProduct">
   <DataNode TextLabel="GUCY2E" GraphId="a6668" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCY2E | guanylate cyclase 2E" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCY2E | guanylate cyclase 2E"/>
-
     <Graphics CenterX="466.6666666666667" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="466.6666666666667" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2985" />
+
     <Xref Database="Entrez Gene" ID="2985"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKAR2B" GraphId="a67e2" Type="GeneProduct" GroupRef="cb90f">
   <DataNode TextLabel="PRKAR2B" GraphId="a67e2" Type="GeneProduct" GroupRef="cb90f">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR2B | protein kinase cAMP-dependent regul..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR2B | protein kinase cAMP-dependent regul..."/>
-
     <Graphics CenterX="231.33333333333331" CenterY="506.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="231.33333333333331" CenterY="506.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5577" />
+
     <Xref Database="Entrez Gene" ID="5577"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCG" GraphId="a687f" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCG" GraphId="a687f" Type="GeneProduct" GroupRef="ff3b9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCG | protein kinase C gamma" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCG | protein kinase C gamma"/>
-
     <Graphics CenterX="1251.9999999999998" CenterY="347.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1251.9999999999998" CenterY="347.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5582" />
+
     <Xref Database="Entrez Gene" ID="5582"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY2" GraphId="a6920" Type="GeneProduct">
   <DataNode TextLabel="ADCY2" GraphId="a6920" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">There is no SwissProt entry for a full-length sequence in mouse.  This EST is from the Affymetrix Murine6500 chip.</Comment>
     <Comment Source="GenMAPP remarks">There is no SwissProt entry for a full-length sequence in mouse.  This EST is from the Affymetrix Murine6500 chip.</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY2 | adenylate cyclase 2 (brain)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY2 | adenylate cyclase 2 (brain)"/>
-
     <Graphics CenterX="250.0" CenterY="712.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.0" CenterY="712.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="108" />
+
     <Xref Database="Entrez Gene" ID="108"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCE" GraphId="a793d" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCE" GraphId="a793d" Type="GeneProduct" GroupRef="ff3b9">
     <Comment Source="GenMAPP remarks">This EST is listed on the Affymetrix Murine6500 chip.  The SwissProt entry name is KPCE MOUSE.</Comment>
     <Comment Source="GenMAPP remarks">This EST is listed on the Affymetrix Murine6500 chip.  The SwissProt entry name is KPCE MOUSE.</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCE | protein kinase C epsilon" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCE | protein kinase C epsilon"/>
-
     <Graphics CenterX="1191.9999999999998" CenterY="406.92517006802734" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1191.9999999999998" CenterY="406.92517006802734" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5581" />
+
     <Xref Database="Entrez Gene" ID="5581"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IGFBP5" GraphId="a801e" Type="GeneProduct">
   <DataNode TextLabel="IGFBP5" GraphId="a801e" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP5 | insulin-like growth factor binding pro..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP5 | insulin-like growth factor binding pro..."/>
-
     <Graphics CenterX="160.0" CenterY="772.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="160.0" CenterY="772.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3488" />
+
     <Xref Database="Entrez Gene" ID="3488"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GRK4" GraphId="a88ca" Type="GeneProduct" GroupRef="e2890">
   <DataNode TextLabel="GRK4" GraphId="a88ca" Type="GeneProduct" GroupRef="e2890">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK4 | G protein-coupled receptor kinase 4" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK4 | G protein-coupled receptor kinase 4"/>
-
     <Graphics CenterX="839.3333333333333" CenterY="178.66666666666669" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="839.3333333333333" CenterY="178.66666666666669" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2868" />
+
     <Xref Database="Entrez Gene" ID="2868"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNB3" GraphId="a8c0b" Type="GeneProduct">
   <DataNode TextLabel="GNB3" GraphId="a8c0b" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB3 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB3 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="406.66666666666663" CenterY="727.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="406.66666666666663" CenterY="727.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2784" />
+
     <Xref Database="Entrez Gene" ID="2784"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG3" GraphId="a90c2" Type="GeneProduct">
   <DataNode TextLabel="GNG3" GraphId="a90c2" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG3 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG3 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="472.33333333333337" CenterY="727.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="472.33333333333337" CenterY="727.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2785" />
+
     <Xref Database="Entrez Gene" ID="2785"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PKIB" GraphId="a9375" Type="GeneProduct" GroupRef="b262c">
   <DataNode TextLabel="PKIB" GraphId="a9375" Type="GeneProduct" GroupRef="b262c">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PKIB | protein kinase (cAMP-dependent catalyti..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PKIB | protein kinase (cAMP-dependent catalyti..."/>
-
     <Graphics CenterX="107.66666666666674" CenterY="495.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="107.66666666666674" CenterY="495.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5570" />
+
     <Xref Database="Entrez Gene" ID="5570"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FOS" GraphId="a9700" Type="GeneProduct" GroupRef="de038">
   <DataNode TextLabel="FOS" GraphId="a9700" Type="GeneProduct" GroupRef="de038">
     <Comment Source="GenMAPP remarks">PMID: 10218980 PMID: 7628395 [</Comment>
     <Comment Source="GenMAPP remarks">PMID: 10218980 PMID: 7628395 [</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="FOS | v-fos FBJ murine osteosarcoma viral oncog..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="FOS | v-fos FBJ murine osteosarcoma viral oncog..."/>
-
     <Graphics CenterX="682.6666666666671" CenterY="796.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="682.6666666666671" CenterY="796.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2353" />
+
     <Xref Database="Entrez Gene" ID="2353"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GRK5" GraphId="aa50b" Type="GeneProduct" GroupRef="b01f5">
   <DataNode TextLabel="GRK5" GraphId="aa50b" Type="GeneProduct" GroupRef="b01f5">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK5 | G protein-coupled receptor kinase 5" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK5 | G protein-coupled receptor kinase 5"/>
-
     <Graphics CenterX="32.33333333333326" CenterY="266.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="32.33333333333326" CenterY="266.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2869" />
+
     <Xref Database="Entrez Gene" ID="2869"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="OXTR" GraphId="aa684" Type="GeneProduct">
   <DataNode TextLabel="OXTR" GraphId="aa684" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="OXTR | oxytocin receptor" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="OXTR | oxytocin receptor"/>
-
     <Graphics CenterX="740.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="740.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5021" />
+
     <Xref Database="Entrez Gene" ID="5021"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MYLK2" GraphId="aaf0e" Type="GeneProduct">
   <DataNode TextLabel="MYLK2" GraphId="aaf0e" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">KML2 MOUSE</Comment>
     <Comment Source="GenMAPP remarks">KML2 MOUSE</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYLK2 | myosin light chain kinase 2 skeletal m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYLK2 | myosin light chain kinase 2 skeletal m..."/>
-
     <Graphics CenterX="797.0" CenterY="580.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="797.0" CenterY="580.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="85366" />
+
     <Xref Database="Entrez Gene" ID="85366"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG12" GraphId="ab67b" Type="GeneProduct">
   <DataNode TextLabel="GNG12" GraphId="ab67b" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG12 | guanine nucleotide binding protein (G p..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG12 | guanine nucleotide binding protein (G p..."/>
-
     <Graphics CenterX="532.6666666666666" CenterY="747.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="532.6666666666666" CenterY="747.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="55970" />
+
     <Xref Database="Entrez Gene" ID="55970"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS2" GraphId="ab727" Type="GeneProduct">
   <DataNode TextLabel="RGS2" GraphId="ab727" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS2 | regulator of G-protein signalling 2 24k..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS2 | regulator of G-protein signalling 2 24k..."/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="173.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="173.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5997" />
+
     <Xref Database="Entrez Gene" ID="5997"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG2" GraphId="ab9bd" Type="GeneProduct">
   <DataNode TextLabel="GNG2" GraphId="ab9bd" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG2 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG2 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="472.33333333333337" CenterY="707.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="472.33333333333337" CenterY="707.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="54331" />
+
     <Xref Database="Entrez Gene" ID="54331"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS6" GraphId="abc52" Type="GeneProduct">
   <DataNode TextLabel="RGS6" GraphId="abc52" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS6 | regulator of G-protein signalling 6" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS6 | regulator of G-protein signalling 6"/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="253.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="253.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="9628" />
+
     <Xref Database="Entrez Gene" ID="9628"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="JUN" GraphId="acae1" Type="GeneProduct" GroupRef="de038">
   <DataNode TextLabel="JUN" GraphId="acae1" Type="GeneProduct" GroupRef="de038">
     <Comment Source="GenMAPP remarks">PMID: 10218980</Comment>
     <Comment Source="GenMAPP remarks">PMID: 10218980</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="JUN | v-jun sarcoma virus 17 oncogene homolog (..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="JUN | v-jun sarcoma virus 17 oncogene homolog (..."/>
-
     <Graphics CenterX="682.6666666666671" CenterY="816.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="682.6666666666671" CenterY="816.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3725" />
+
     <Xref Database="Entrez Gene" ID="3725"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY3" GraphId="ad089" Type="GeneProduct">
   <DataNode TextLabel="ADCY3" GraphId="ad089" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY3 | adenylate cyclase 3" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY3 | adenylate cyclase 3"/>
-
     <Graphics CenterX="250.0" CenterY="732.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.0" CenterY="732.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="109" />
+
     <Xref Database="Entrez Gene" ID="109"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG7" GraphId="ad169" Type="GeneProduct">
   <DataNode TextLabel="GNG7" GraphId="ad169" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG7 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG7 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="532.6666666666666" CenterY="687.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="532.6666666666666" CenterY="687.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2788" />
+
     <Xref Database="Entrez Gene" ID="2788"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKACB" GraphId="ad751" Type="GeneProduct" GroupRef="cb90f">
   <DataNode TextLabel="PRKACB" GraphId="ad751" Type="GeneProduct" GroupRef="cb90f">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKACB | protein kinase cAMP-dependent cataly..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKACB | protein kinase cAMP-dependent cataly..."/>
-
     <Graphics CenterX="231.33333333333331" CenterY="546.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="231.33333333333331" CenterY="546.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5567" />
+
     <Xref Database="Entrez Gene" ID="5567"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CREBL1" GraphId="ae2ef" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="CREBL1" GraphId="ae2ef" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CREBL1 | cAMP responsive element binding protei..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CREBL1 | cAMP responsive element binding protei..."/>
-
     <Graphics CenterX="132.33333333333331" CenterY="612.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="132.33333333333331" CenterY="612.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1388" />
+
     <Xref Database="Entrez Gene" ID="1388"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ACTA2" GraphId="af2af" Type="GeneProduct" GroupRef="b38f8">
   <DataNode TextLabel="ACTA2" GraphId="af2af" Type="GeneProduct" GroupRef="b38f8">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTA2 | actin alpha 2 smooth muscle aorta" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTA2 | actin alpha 2 smooth muscle aorta"/>
-
     <Graphics CenterX="643.3333333333334" CenterY="611.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="643.3333333333334" CenterY="611.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="59" />
+
     <Xref Database="Entrez Gene" ID="59"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAMP2" GraphId="b0d8d" Type="GeneProduct" GroupRef="bcf55">
   <DataNode TextLabel="RAMP2" GraphId="b0d8d" Type="GeneProduct" GroupRef="bcf55">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAMP2 | receptor (calcitonin) activity modifyin..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAMP2 | receptor (calcitonin) activity modifyin..."/>
-
     <Graphics CenterX="250.33333333333331" CenterY="200.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.33333333333331" CenterY="200.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10266" />
+
     <Xref Database="Entrez Gene" ID="10266"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADMR" GraphId="b0eff" Type="GeneProduct" GroupRef="aa636">
   <DataNode TextLabel="ADMR" GraphId="b0eff" Type="GeneProduct" GroupRef="aa636">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADMR | adrenomedullin receptor" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADMR | adrenomedullin receptor"/>
-
     <Graphics CenterX="173.33333333333334" CenterY="150.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="173.33333333333334" CenterY="150.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="11318" />
+
     <Xref Database="Entrez Gene" ID="11318"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CALCA" GraphId="b14d3" Type="GeneProduct">
   <DataNode TextLabel="CALCA" GraphId="b14d3" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">CRF HUMAN  PMID: 11854458</Comment>
     <Comment Source="GenMAPP remarks">CRF HUMAN  PMID: 11854458</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALCA | calcitonin/calcitonin-related polypepti..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALCA | calcitonin/calcitonin-related polypepti..."/>
-
     <Graphics CenterX="250.0" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.0" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="796" />
+
     <Xref Database="Entrez Gene" ID="796"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY8" GraphId="b1983" Type="GeneProduct">
   <DataNode TextLabel="ADCY8" GraphId="b1983" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY8 | adenylate cyclase 8 (brain)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY8 | adenylate cyclase 8 (brain)"/>
-
     <Graphics CenterX="318.66666666666663" CenterY="732.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="318.66666666666663" CenterY="732.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="114" />
+
     <Xref Database="Entrez Gene" ID="114"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY1" GraphId="b209c" Type="GeneProduct">
   <DataNode TextLabel="ADCY1" GraphId="b209c" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">CYA1 HUMAN</Comment>
     <Comment Source="GenMAPP remarks">CYA1 HUMAN</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY1 | adenylate cyclase 1 (brain)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY1 | adenylate cyclase 1 (brain)"/>
-
     <Graphics CenterX="250.0" CenterY="692.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.0" CenterY="692.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="107" />
+
     <Xref Database="Entrez Gene" ID="107"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ARRB2" GraphId="b27a1" Type="GeneProduct" GroupRef="e2890">
   <DataNode TextLabel="ARRB2" GraphId="b27a1" Type="GeneProduct" GroupRef="e2890">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB2 | arrestin beta 2" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB2 | arrestin beta 2"/>
-
     <Graphics CenterX="899.3333333333333" CenterY="218.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="899.3333333333333" CenterY="218.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="409" />
+
     <Xref Database="Entrez Gene" ID="409"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATF1" GraphId="b2e46" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="ATF1" GraphId="b2e46" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF1 | activating transcription factor 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF1 | activating transcription factor 1"/>
-
     <Graphics CenterX="63.0" CenterY="572.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="63.0" CenterY="572.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="466" />
+
     <Xref Database="Entrez Gene" ID="466"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NOS1" GraphId="b343a" Type="GeneProduct" GroupRef="dc048">
   <DataNode TextLabel="NOS1" GraphId="b343a" Type="GeneProduct" GroupRef="dc048">
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="NOS1 | nitric oxide synthase 1 (neuronal)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="NOS1 | nitric oxide synthase 1 (neuronal)"/>
-
     <Graphics CenterX="476.6666666666667" CenterY="466.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="476.6666666666667" CenterY="466.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="4842" />
+
     <Xref Database="Entrez Gene" ID="4842"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GRK5" GraphId="b36cd" Type="GeneProduct" GroupRef="e2890">
   <DataNode TextLabel="GRK5" GraphId="b36cd" Type="GeneProduct" GroupRef="e2890">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK5 | G protein-coupled receptor kinase 5" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK5 | G protein-coupled receptor kinase 5"/>
-
     <Graphics CenterX="839.3333333333333" CenterY="198.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="839.3333333333333" CenterY="198.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2869" />
+
     <Xref Database="Entrez Gene" ID="2869"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS17" GraphId="b43ea" Type="GeneProduct">
   <DataNode TextLabel="RGS17" GraphId="b43ea" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS17 | regulator of G-protein signalling 17" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS17 | regulator of G-protein signalling 17"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="233.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="233.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="26575" />
+
     <Xref Database="Entrez Gene" ID="26575"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCH" GraphId="b5442" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCH" GraphId="b5442" Type="GeneProduct" GroupRef="ff3b9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCH | protein kinase C eta" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCH | protein kinase C eta"/>
-
     <Graphics CenterX="1251.9999999999998" CenterY="367.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1251.9999999999998" CenterY="367.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5583" />
+
     <Xref Database="Entrez Gene" ID="5583"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RYR2" GraphId="b54bb" Type="GeneProduct" GroupRef="b8909">
   <DataNode TextLabel="RYR2" GraphId="b54bb" Type="GeneProduct" GroupRef="b8909">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RYR2 | ryanodine receptor 2 (cardiac)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RYR2 | ryanodine receptor 2 (cardiac)"/>
-
     <Graphics CenterX="644.3333333333334" CenterY="452.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="644.3333333333334" CenterY="452.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6262" />
+
     <Xref Database="Entrez Gene" ID="6262"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS18" GraphId="b5c1f" Type="GeneProduct">
   <DataNode TextLabel="RGS18" GraphId="b5c1f" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS18 | regulator of G-protein signalling 18" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS18 | regulator of G-protein signalling 18"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="253.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="253.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="64407" />
+
     <Xref Database="Entrez Gene" ID="64407"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="YWHAB" GraphId="b5ebe" Type="GeneProduct" GroupRef="a9e43">
   <DataNode TextLabel="YWHAB" GraphId="b5ebe" Type="GeneProduct" GroupRef="a9e43">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAB | tyrosine 3-monooxygenase/tryptophan 5-m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAB | tyrosine 3-monooxygenase/tryptophan 5-m..."/>
-
     <Graphics CenterX="1196.6138735420502" CenterY="486.6666666666665" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1196.6138735420502" CenterY="486.6666666666665" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="7529" />
+
     <Xref Database="Entrez Gene" ID="7529"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IL6" GraphId="b64a3" Type="GeneProduct" GroupRef="c509b">
   <DataNode TextLabel="IL6" GraphId="b64a3" Type="GeneProduct" GroupRef="c509b">
Line 264: Line 265:
22. Dudley, D.Jl, et. Al. (1992) J. Clin. Endocrinol. Metab. 74, 884-889
22. Dudley, D.Jl, et. Al. (1992) J. Clin. Endocrinol. Metab. 74, 884-889
23. Romero, R., et. Al, Am. J. Obstet. Gynecol. 167, 863-872.</Comment>
23. Romero, R., et. Al, Am. J. Obstet. Gynecol. 167, 863-872.</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IL6 | interleukin 6 (interferon beta 2)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IL6 | interleukin 6 (interferon beta 2)"/>
-
     <Graphics CenterX="788.0000000000005" CenterY="920.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="788.0000000000005" CenterY="920.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3569" />
+
     <Xref Database="Entrez Gene" ID="3569"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GRK6" GraphId="b6ea2" Type="GeneProduct" GroupRef="e2890">
   <DataNode TextLabel="GRK6" GraphId="b6ea2" Type="GeneProduct" GroupRef="e2890">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK6 | G protein-coupled receptor kinase 6" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK6 | G protein-coupled receptor kinase 6"/>
-
     <Graphics CenterX="899.3333333333333" CenterY="178.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="899.3333333333333" CenterY="178.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2870" />
+
     <Xref Database="Entrez Gene" ID="2870"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RCP9" GraphId="b7107" Type="GeneProduct" GroupRef="bcf55">
   <DataNode TextLabel="RCP9" GraphId="b7107" Type="GeneProduct" GroupRef="bcf55">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RCP9 | calcitonin gene-related peptide-receptor..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RCP9 | calcitonin gene-related peptide-receptor..."/>
-
     <Graphics CenterX="250.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="27297" />
+
     <Xref Database="Entrez Gene" ID="27297"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="LGR7" GraphId="b79ad" Type="GeneProduct" GroupRef="ca8b3">
   <DataNode TextLabel="LGR7" GraphId="b79ad" Type="GeneProduct" GroupRef="ca8b3">
     <Comment Source="GenMAPP remarks">PMID: 11809971</Comment>
     <Comment Source="GenMAPP remarks">PMID: 11809971</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="LGR7 | leucine-rich repeat-containing G protein..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="LGR7 | leucine-rich repeat-containing G protein..."/>
-
     <Graphics CenterX="96.66666666666667" CenterY="150.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="96.66666666666667" CenterY="150.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="59350" />
+
     <Xref Database="Entrez Gene" ID="59350"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CNN1" GraphId="b7f49" Type="GeneProduct" GroupRef="af3f8">
   <DataNode TextLabel="CNN1" GraphId="b7f49" Type="GeneProduct" GroupRef="af3f8">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CNN1 | calponin 1 basic smooth muscle" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CNN1 | calponin 1 basic smooth muscle"/>
-
     <Graphics CenterX="976.6666666666666" CenterY="470.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="976.6666666666666" CenterY="470.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1264" />
+
     <Xref Database="Entrez Gene" ID="1264"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="YWHAH" GraphId="b91ee" Type="GeneProduct" GroupRef="a9e43">
   <DataNode TextLabel="YWHAH" GraphId="b91ee" Type="GeneProduct" GroupRef="a9e43">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAH | tyrosine 3-monooxygenase/tryptophan 5-m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAH | tyrosine 3-monooxygenase/tryptophan 5-m..."/>
-
     <Graphics CenterX="1196.6138735420502" CenterY="526.0527931246163" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1196.6138735420502" CenterY="526.0527931246163" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="7533" />
+
     <Xref Database="Entrez Gene" ID="7533"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CAMK2G" GraphId="b9259" Type="GeneProduct" GroupRef="da70b">
   <DataNode TextLabel="CAMK2G" GraphId="b9259" Type="GeneProduct" GroupRef="da70b">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2G | calcium/calmodulin-dependent protein k..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2G | calcium/calmodulin-dependent protein k..."/>
-
     <Graphics CenterX="1175.9999999999998" CenterY="670.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1175.9999999999998" CenterY="670.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="818" />
+
     <Xref Database="Entrez Gene" ID="818"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS7" GraphId="b9f6b" Type="GeneProduct">
   <DataNode TextLabel="RGS7" GraphId="b9f6b" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS7 | regulator of G-protein signalling 7" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS7 | regulator of G-protein signalling 7"/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="273.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="273.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6000" />
+
     <Xref Database="Entrez Gene" ID="6000"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MYL4" GraphId="bab36" Type="GeneProduct" GroupRef="e8d60">
   <DataNode TextLabel="MYL4" GraphId="bab36" Type="GeneProduct" GroupRef="e8d60">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYL4 | myosin light polypeptide 4 alkali; atr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYL4 | myosin light polypeptide 4 alkali; atr..."/>
-
     <Graphics CenterX="933.6666666666666" CenterY="614.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="933.6666666666666" CenterY="614.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="4635" />
+
     <Xref Database="Entrez Gene" ID="4635"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS1" GraphId="bb0b7" Type="GeneProduct">
   <DataNode TextLabel="RGS1" GraphId="bb0b7" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS1 | regulator of G-protein signalling 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS1 | regulator of G-protein signalling 1"/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="153.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="153.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5996" />
+
     <Xref Database="Entrez Gene" ID="5996"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCB1" GraphId="bb4cb" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCB1" GraphId="bb4cb" Type="GeneProduct" GroupRef="ff3b9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCB1 | protein kinase C beta 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCB1 | protein kinase C beta 1"/>
-
     <Graphics CenterX="1191.9999999999998" CenterY="367.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1191.9999999999998" CenterY="367.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5579" />
+
     <Xref Database="Entrez Gene" ID="5579"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MYLK2" GraphId="bb691" Type="GeneProduct">
   <DataNode TextLabel="MYLK2" GraphId="bb691" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">KML2 MOUSE</Comment>
     <Comment Source="GenMAPP remarks">KML2 MOUSE</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYLK2 | myosin light chain kinase 2 skeletal m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYLK2 | myosin light chain kinase 2 skeletal m..."/>
-
     <Graphics CenterX="862.0" CenterY="536.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="862.0" CenterY="536.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="85366" />
+
     <Xref Database="Entrez Gene" ID="85366"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="EDG2" GraphId="bb7d5" Type="GeneProduct">
   <DataNode TextLabel="EDG2" GraphId="bb7d5" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="EDG2 | endothelial differentiation lysophospha..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="EDG2 | endothelial differentiation lysophospha..."/>
-
     <Graphics CenterX="640.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="640.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1902" />
+
     <Xref Database="Entrez Gene" ID="1902"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAMP3" GraphId="bc736" Type="GeneProduct" GroupRef="bcf55">
   <DataNode TextLabel="RAMP3" GraphId="bc736" Type="GeneProduct" GroupRef="bcf55">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAMP3 | receptor (calcitonin) activity modifyin..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAMP3 | receptor (calcitonin) activity modifyin..."/>
-
     <Graphics CenterX="250.33333333333331" CenterY="220.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.33333333333331" CenterY="220.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10268" />
+
     <Xref Database="Entrez Gene" ID="10268"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CAMK2D" GraphId="bd5c4" Type="GeneProduct" GroupRef="da70b">
   <DataNode TextLabel="CAMK2D" GraphId="bd5c4" Type="GeneProduct" GroupRef="da70b">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2D | calcium/calmodulin-dependent protein k..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2D | calcium/calmodulin-dependent protein k..."/>
-
     <Graphics CenterX="1175.9999999999998" CenterY="650.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1175.9999999999998" CenterY="650.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="817" />
+
     <Xref Database="Entrez Gene" ID="817"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCQ" GraphId="bdee2" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCQ" GraphId="bdee2" Type="GeneProduct" GroupRef="ff3b9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCQ | protein kinase C theta" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCQ | protein kinase C theta"/>
-
     <Graphics CenterX="1251.9999999999998" CenterY="407.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1251.9999999999998" CenterY="407.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5588" />
+
     <Xref Database="Entrez Gene" ID="5588"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NOS3" GraphId="be628" Type="GeneProduct" GroupRef="dc048">
   <DataNode TextLabel="NOS3" GraphId="be628" Type="GeneProduct" GroupRef="dc048">
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="NOS3 | nitric oxide synthase 3 (endothelial cel..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="NOS3 | nitric oxide synthase 3 (endothelial cel..."/>
-
     <Graphics CenterX="476.6666666666667" CenterY="486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="476.6666666666667" CenterY="486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="4846" />
+
     <Xref Database="Entrez Gene" ID="4846"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CALD1" GraphId="beb0c" Type="GeneProduct">
   <DataNode TextLabel="CALD1" GraphId="beb0c" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALD1 | caldesmon 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALD1 | caldesmon 1"/>
-
     <Graphics CenterX="1053.3333333333333" CenterY="563.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1053.3333333333333" CenterY="563.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="800" />
+
     <Xref Database="Entrez Gene" ID="800"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GSTO1" GraphId="bf28c" Type="GeneProduct" GroupRef="b8909">
   <DataNode TextLabel="GSTO1" GraphId="bf28c" Type="GeneProduct" GroupRef="b8909">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GSTO1 | glutathione S-transferase omega 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GSTO1 | glutathione S-transferase omega 1"/>
-
     <Graphics CenterX="644.3333333333334" CenterY="492.33333333333326" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="644.3333333333334" CenterY="492.33333333333326" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="9446" />
+
     <Xref Database="Entrez Gene" ID="9446"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CRH" GraphId="bf458" Type="GeneProduct">
   <DataNode TextLabel="CRH" GraphId="bf458" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">CRF HUMAN  PMID: 11854458</Comment>
     <Comment Source="GenMAPP remarks">CRF HUMAN  PMID: 11854458</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CRH | corticotropin releasing hormone" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CRH | corticotropin releasing hormone"/>
-
     <Graphics CenterX="330.0" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="330.0" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1392" />
+
     <Xref Database="Entrez Gene" ID="1392"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATP" GraphId="c03e8" Type="Metabolite">
   <DataNode TextLabel="ATP" GraphId="c03e8" Type="Metabolite">
-
     <Graphics CenterX="915.6666666666666" CenterY="538.6666666666666" Width="31.333333333333332" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="915.6666666666666" CenterY="538.6666666666666" Width="31.333333333333332" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="CAS" ID="1927-31-7" />
+
     <Xref Database="CAS" ID="1927-31-7"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCA" GraphId="c17cd" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCA" GraphId="c17cd" Type="GeneProduct" GroupRef="ff3b9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCA | protein kinase C alpha" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCA | protein kinase C alpha"/>
-
     <Graphics CenterX="1191.9999999999998" CenterY="347.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1191.9999999999998" CenterY="347.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5578" />
+
     <Xref Database="Entrez Gene" ID="5578"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="YWHAZ" GraphId="c1939" Type="GeneProduct" GroupRef="a9e43">
   <DataNode TextLabel="YWHAZ" GraphId="c1939" Type="GeneProduct" GroupRef="a9e43">
     <Comment Source="GenMAPP remarks">PMID: 9861170 PMID: 1317796</Comment>
     <Comment Source="GenMAPP remarks">PMID: 9861170 PMID: 1317796</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-m..."/>
-
     <Graphics CenterX="1256.61387354205" CenterY="526.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1256.61387354205" CenterY="526.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="7534" />
+
     <Xref Database="Entrez Gene" ID="7534"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GRK4" GraphId="c1c8f" Type="GeneProduct" GroupRef="b01f5">
   <DataNode TextLabel="GRK4" GraphId="c1c8f" Type="GeneProduct" GroupRef="b01f5">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK4 | G protein-coupled receptor kinase 4" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK4 | G protein-coupled receptor kinase 4"/>
-
     <Graphics CenterX="32.33333333333326" CenterY="246.66666666666669" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="32.33333333333326" CenterY="246.66666666666669" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2868" />
+
     <Xref Database="Entrez Gene" ID="2868"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CNN2" GraphId="c3f03" Type="GeneProduct" GroupRef="af3f8">
   <DataNode TextLabel="CNN2" GraphId="c3f03" Type="GeneProduct" GroupRef="af3f8">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CNN2 | calponin 2" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CNN2 | calponin 2"/>
-
     <Graphics CenterX="976.6666666666666" CenterY="490.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="976.6666666666666" CenterY="490.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1265" />
+
     <Xref Database="Entrez Gene" ID="1265"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKAR2A" GraphId="c415e" Type="GeneProduct" GroupRef="cb90f">
   <DataNode TextLabel="PRKAR2A" GraphId="c415e" Type="GeneProduct" GroupRef="cb90f">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR2A | protein kinase cAMP-dependent regul..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR2A | protein kinase cAMP-dependent regul..."/>
-
     <Graphics CenterX="231.33333333333331" CenterY="486.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="231.33333333333331" CenterY="486.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5576" />
+
     <Xref Database="Entrez Gene" ID="5576"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ARRB2" GraphId="c47dc" Type="GeneProduct" GroupRef="b01f5">
   <DataNode TextLabel="ARRB2" GraphId="c47dc" Type="GeneProduct" GroupRef="b01f5">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB2 | arrestin beta 2" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB2 | arrestin beta 2"/>
-
     <Graphics CenterX="92.33333333333326" CenterY="286.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="92.33333333333326" CenterY="286.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="409" />
+
     <Xref Database="Entrez Gene" ID="409"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNB2" GraphId="c5d97" Type="GeneProduct">
   <DataNode TextLabel="GNB2" GraphId="c5d97" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB2 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB2 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="406.66666666666663" CenterY="707.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="406.66666666666663" CenterY="707.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2783" />
+
     <Xref Database="Entrez Gene" ID="2783"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG11" GraphId="c6e12" Type="GeneProduct">
   <DataNode TextLabel="GNG11" GraphId="c6e12" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG11 | guanine nucleotide binding protein (G p..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG11 | guanine nucleotide binding protein (G p..."/>
-
     <Graphics CenterX="532.6666666666666" CenterY="727.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="532.6666666666666" CenterY="727.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2791" />
+
     <Xref Database="Entrez Gene" ID="2791"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="OXTR" GraphId="c758d" Type="GeneProduct" GroupRef="e60e9">
   <DataNode TextLabel="OXTR" GraphId="c758d" Type="GeneProduct" GroupRef="e60e9">
     <Comment Source="GenMAPP remarks">Sladek SM, Westerhausen-Larson A, Roberts JM.
     <Comment Source="GenMAPP remarks">Sladek SM, Westerhausen-Larson A, Roberts JM.
PMID: 10377025</Comment>
PMID: 10377025</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="OXTR | oxytocin receptor" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="OXTR | oxytocin receptor"/>
-
     <Graphics CenterX="946.0000000000005" CenterY="864.0000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="946.0000000000005" CenterY="864.0000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5021" />
+
     <Xref Database="Entrez Gene" ID="5021"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IGFBP4" GraphId="c85c0" Type="GeneProduct">
   <DataNode TextLabel="IGFBP4" GraphId="c85c0" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP4 | insulin-like growth factor binding pro..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP4 | insulin-like growth factor binding pro..."/>
-
     <Graphics CenterX="160.0" CenterY="752.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="160.0" CenterY="752.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3487" />
+
     <Xref Database="Entrez Gene" ID="3487"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RYR3" GraphId="c881a" Type="GeneProduct" GroupRef="b8909">
   <DataNode TextLabel="RYR3" GraphId="c881a" Type="GeneProduct" GroupRef="b8909">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RYR3 | ryanodine receptor 3" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RYR3 | ryanodine receptor 3"/>
-
     <Graphics CenterX="644.3333333333334" CenterY="472.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="644.3333333333334" CenterY="472.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6263" />
+
     <Xref Database="Entrez Gene" ID="6263"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS10" GraphId="ca15b" Type="GeneProduct">
   <DataNode TextLabel="RGS10" GraphId="ca15b" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS10 | regulator of G-protein signalling 10" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS10 | regulator of G-protein signalling 10"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="153.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="153.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6001" />
+
     <Xref Database="Entrez Gene" ID="6001"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="DGKZ" GraphId="ca546" Type="GeneProduct">
   <DataNode TextLabel="DGKZ" GraphId="ca546" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="DGKZ | diacylglycerol kinase zeta 104kDa" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="DGKZ | diacylglycerol kinase zeta 104kDa"/>
-
     <Graphics CenterX="826.0" CenterY="273.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="826.0" CenterY="273.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8525" />
+
     <Xref Database="Entrez Gene" ID="8525"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS5" GraphId="cadda" Type="GeneProduct">
   <DataNode TextLabel="RGS5" GraphId="cadda" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS5 | regulator of G-protein signalling 5" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS5 | regulator of G-protein signalling 5"/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="233.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="233.00000000000003" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8490" />
+
     <Xref Database="Entrez Gene" ID="8490"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATP2A2" GraphId="cb5f1" Type="GeneProduct" GroupRef="b8909">
   <DataNode TextLabel="ATP2A2" GraphId="cb5f1" Type="GeneProduct" GroupRef="b8909">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP2A2 | ATPase Ca++ transporting cardiac mus..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATP2A2 | ATPase Ca++ transporting cardiac mus..."/>
-
     <Graphics CenterX="644.3333333333334" CenterY="392.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="644.3333333333334" CenterY="392.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="488" />
+
     <Xref Database="Entrez Gene" ID="488"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IGFBP2" GraphId="cb61e" Type="GeneProduct">
   <DataNode TextLabel="IGFBP2" GraphId="cb61e" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP2 | insulin-like growth factor binding pro..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP2 | insulin-like growth factor binding pro..."/>
-
     <Graphics CenterX="160.0" CenterY="712.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="160.0" CenterY="712.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3485" />
+
     <Xref Database="Entrez Gene" ID="3485"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS20" GraphId="cd585" Type="GeneProduct">
   <DataNode TextLabel="RGS20" GraphId="cd585" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS20 | regulator of G-protein signalling 20" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS20 | regulator of G-protein signalling 20"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="293.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="293.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8601" />
+
     <Xref Database="Entrez Gene" ID="8601"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNAQ" GraphId="cd799" Type="GeneProduct">
   <DataNode TextLabel="GNAQ" GraphId="cd799" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAQ | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAQ | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="740.0" CenterY="220.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="740.0" CenterY="220.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2776" />
+
     <Xref Database="Entrez Gene" ID="2776"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Cyclic AMP" GraphId="cded0" Type="Metabolite">
   <DataNode TextLabel="Cyclic AMP" GraphId="cded0" Type="Metabolite">
-
     <Graphics CenterX="625.5" CenterY="205.0" Width="63.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="625.5" CenterY="205.0" Width="63.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000058" />
+
     <Xref Database="HMDB" ID="HMDB0000058"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNB5" GraphId="ce263" Type="GeneProduct">
   <DataNode TextLabel="GNB5" GraphId="ce263" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB5 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB5 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="406.66666666666663" CenterY="767.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="406.66666666666663" CenterY="767.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10681" />
+
     <Xref Database="Entrez Gene" ID="10681"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="YWHAE" GraphId="cf09c" Type="GeneProduct" GroupRef="a9e43">
   <DataNode TextLabel="YWHAE" GraphId="cf09c" Type="GeneProduct" GroupRef="a9e43">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAE | tyrosine 3-monooxygenase/tryptophan 5-m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAE | tyrosine 3-monooxygenase/tryptophan 5-m..."/>
-
     <Graphics CenterX="1196.6138735420502" CenterY="506.6666666666666" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1196.6138735420502" CenterY="506.6666666666666" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="7531" />
+
     <Xref Database="Entrez Gene" ID="7531"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="OXT" GraphId="cf1e9" Type="GeneProduct">
   <DataNode TextLabel="OXT" GraphId="cf1e9" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">MGI:97453</Comment>
     <Comment Source="GenMAPP remarks">MGI:97453</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="OXT | oxytocin prepro- (neurophysin I)" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="OXT | oxytocin prepro- (neurophysin I)"/>
-
     <Graphics CenterX="740.0" CenterY="110.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="740.0" CenterY="110.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5020" />
+
     <Xref Database="Entrez Gene" ID="5020"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKAR1A" GraphId="cf296" Type="GeneProduct" GroupRef="cb90f">
   <DataNode TextLabel="PRKAR1A" GraphId="cf296" Type="GeneProduct" GroupRef="cb90f">
     <Comment Source="GenMAPP remarks">KAP0 HUMAN</Comment>
     <Comment Source="GenMAPP remarks">KAP0 HUMAN</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR1A | protein kinase cAMP-dependent regul..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR1A | protein kinase cAMP-dependent regul..."/>
-
     <Graphics CenterX="231.33333333333331" CenterY="446.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="231.33333333333331" CenterY="446.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5573" />
+
     <Xref Database="Entrez Gene" ID="5573"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS9" GraphId="d01f9" Type="GeneProduct">
   <DataNode TextLabel="RGS9" GraphId="d01f9" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS9 | regulator of G-protein signalling 9" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS9 | regulator of G-protein signalling 9"/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="293.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="293.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8787" />
+
     <Xref Database="Entrez Gene" ID="8787"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SFN" GraphId="d0418" Type="GeneProduct" GroupRef="a9e43">
   <DataNode TextLabel="SFN" GraphId="d0418" Type="GeneProduct" GroupRef="a9e43">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="SFN | stratifin" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="SFN | stratifin"/>
-
     <Graphics CenterX="1256.6138735420502" CenterY="486.66666666666663" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1256.6138735420502" CenterY="486.66666666666663" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2810" />
+
     <Xref Database="Entrez Gene" ID="2810"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY7" GraphId="d0cd8" Type="GeneProduct">
   <DataNode TextLabel="ADCY7" GraphId="d0cd8" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY7 | adenylate cyclase 7" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY7 | adenylate cyclase 7"/>
-
     <Graphics CenterX="318.66666666666663" CenterY="712.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="318.66666666666663" CenterY="712.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="113" />
+
     <Xref Database="Entrez Gene" ID="113"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATF5" GraphId="d0f38" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="ATF5" GraphId="d0f38" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF5 | activating transcription factor 5" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF5 | activating transcription factor 5"/>
-
     <Graphics CenterX="63.0" CenterY="652.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="63.0" CenterY="652.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="22809" />
+
     <Xref Database="Entrez Gene" ID="22809"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLCG2" GraphId="d1223" Type="GeneProduct" GroupRef="f2693">
   <DataNode TextLabel="PLCG2" GraphId="d1223" Type="GeneProduct" GroupRef="f2693">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCG2 | phospholipase C gamma 2 (phosphatidyli..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCG2 | phospholipase C gamma 2 (phosphatidyli..."/>
-
     <Graphics CenterX="1271.9999999999998" CenterY="670.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1271.9999999999998" CenterY="670.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5336" />
+
     <Xref Database="Entrez Gene" ID="5336"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IL1B" GraphId="d152d" Type="GeneProduct" GroupRef="c509b">
   <DataNode TextLabel="IL1B" GraphId="d152d" Type="GeneProduct" GroupRef="c509b">
Line 525: Line 526:
22. Dudley, D.Jl, et. Al. (1992) J. Clin. Endocrinol. Metab. 74, 884-889
22. Dudley, D.Jl, et. Al. (1992) J. Clin. Endocrinol. Metab. 74, 884-889
23. Romero, R., et. Al, Am. J. Obstet. Gynecol. 167, 863-872.</Comment>
23. Romero, R., et. Al, Am. J. Obstet. Gynecol. 167, 863-872.</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IL1B | interleukin 1 beta" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IL1B | interleukin 1 beta"/>
-
     <Graphics CenterX="788.0000000000005" CenterY="900.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="788.0000000000005" CenterY="900.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3553" />
+
     <Xref Database="Entrez Gene" ID="3553"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG5" GraphId="d1649" Type="GeneProduct">
   <DataNode TextLabel="GNG5" GraphId="d1649" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG5 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG5 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="472.33333333333337" CenterY="767.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="472.33333333333337" CenterY="767.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2787" />
+
     <Xref Database="Entrez Gene" ID="2787"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADM" GraphId="d2491" Type="GeneProduct">
   <DataNode TextLabel="ADM" GraphId="d2491" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADM | adrenomedullin" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADM | adrenomedullin"/>
-
     <Graphics CenterX="173.33333333333334" CenterY="101.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="173.33333333333334" CenterY="101.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="133" />
+
     <Xref Database="Entrez Gene" ID="133"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS16" GraphId="d2fab" Type="GeneProduct">
   <DataNode TextLabel="RGS16" GraphId="d2fab" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS16 | regulator of G-protein signalling 16" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS16 | regulator of G-protein signalling 16"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="213.00000000000034" Width="60.0" Height="20.00000000000003" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="213.00000000000034" Width="60.0" Height="20.00000000000003" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6004" />
+
     <Xref Database="Entrez Gene" ID="6004"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ITPR3" GraphId="d3ad5" Type="GeneProduct" GroupRef="a15ef">
   <DataNode TextLabel="ITPR3" GraphId="d3ad5" Type="GeneProduct" GroupRef="a15ef">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITPR3 | inositol 145-triphosphate receptor t..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITPR3 | inositol 145-triphosphate receptor t..."/>
-
     <Graphics CenterX="646.3333333333333" CenterY="344.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="646.3333333333333" CenterY="344.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3710" />
+
     <Xref Database="Entrez Gene" ID="3710"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKD1" GraphId="d902e" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKD1" GraphId="d902e" Type="GeneProduct" GroupRef="ff3b9">
     <Comment Source="GenMAPP remarks">KPCM HUMAN</Comment>
     <Comment Source="GenMAPP remarks">KPCM HUMAN</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKD1 | protein kinase D1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKD1 | protein kinase D1"/>
-
     <Graphics CenterX="1251.9999999999998" CenterY="387.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1251.9999999999998" CenterY="387.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5587" />
+
     <Xref Database="Entrez Gene" ID="5587"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ACTG1" GraphId="d97c8" Type="GeneProduct" GroupRef="b38f8">
   <DataNode TextLabel="ACTG1" GraphId="d97c8" Type="GeneProduct" GroupRef="b38f8">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTG1 | actin gamma 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTG1 | actin gamma 1"/>
-
     <Graphics CenterX="643.3333333333334" CenterY="671.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="643.3333333333334" CenterY="671.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="71" />
+
     <Xref Database="Entrez Gene" ID="71"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG8" GraphId="da7b0" Type="GeneProduct">
   <DataNode TextLabel="GNG8" GraphId="da7b0" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG8 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG8 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="532.6666666666666" CenterY="707.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="532.6666666666666" CenterY="707.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="94235" />
+
     <Xref Database="Entrez Gene" ID="94235"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="LGR8" GraphId="db337" Type="GeneProduct" GroupRef="ca8b3">
   <DataNode TextLabel="LGR8" GraphId="db337" Type="GeneProduct" GroupRef="ca8b3">
     <Comment Source="GenMAPP remarks">PMID: 11809971 LGR8 MOUSE</Comment>
     <Comment Source="GenMAPP remarks">PMID: 11809971 LGR8 MOUSE</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="LGR8 | leucine-rich repeat-containing G protein..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="LGR8 | leucine-rich repeat-containing G protein..."/>
-
     <Graphics CenterX="96.66666666666667" CenterY="170.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="96.66666666666667" CenterY="170.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="122042" />
+
     <Xref Database="Entrez Gene" ID="122042"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNB4" GraphId="dccd3" Type="GeneProduct">
   <DataNode TextLabel="GNB4" GraphId="dccd3" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB4 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB4 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="406.66666666666663" CenterY="747.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="406.66666666666663" CenterY="747.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="59345" />
+
     <Xref Database="Entrez Gene" ID="59345"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKAR1B" GraphId="dd475" Type="GeneProduct" GroupRef="cb90f">
   <DataNode TextLabel="PRKAR1B" GraphId="dd475" Type="GeneProduct" GroupRef="cb90f">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR1B | protein kinase cAMP-dependent regul..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR1B | protein kinase cAMP-dependent regul..."/>
-
     <Graphics CenterX="231.33333333333331" CenterY="466.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="231.33333333333331" CenterY="466.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5575" />
+
     <Xref Database="Entrez Gene" ID="5575"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS19" GraphId="de5c1" Type="GeneProduct">
   <DataNode TextLabel="RGS19" GraphId="de5c1" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS19 | regulator of G-protein signalling 19" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS19 | regulator of G-protein signalling 19"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="273.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="273.0000000000001" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10287" />
+
     <Xref Database="Entrez Gene" ID="10287"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADP" GraphId="def10" Type="Metabolite">
   <DataNode TextLabel="ADP" GraphId="def10" Type="Metabolite">
-
     <Graphics CenterX="938.0" CenterY="564.0" Width="33.333333333333336" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="938.0" CenterY="564.0" Width="33.333333333333336" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="CAS" ID="58-64-0" />
+
     <Xref Database="CAS" ID="58-64-0"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ACTB" GraphId="df201" Type="GeneProduct" GroupRef="b38f8">
   <DataNode TextLabel="ACTB" GraphId="df201" Type="GeneProduct" GroupRef="b38f8">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTB | actin beta" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTB | actin beta"/>
-
     <Graphics CenterX="643.3333333333334" CenterY="631.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="643.3333333333334" CenterY="631.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="60" />
+
     <Xref Database="Entrez Gene" ID="60"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CORIN" GraphId="e04fa" Type="GeneProduct">
   <DataNode TextLabel="CORIN" GraphId="e04fa" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">MGI:97367</Comment>
     <Comment Source="GenMAPP remarks">MGI:97367</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CORIN | corin serine protease" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CORIN | corin serine protease"/>
-
     <Graphics CenterX="420.0" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="420.0" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10699" />
+
     <Xref Database="Entrez Gene" ID="10699"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GABPB2" GraphId="e0c43" Type="GeneProduct" GroupRef="e5925">
   <DataNode TextLabel="GABPB2" GraphId="e0c43" Type="GeneProduct" GroupRef="e5925">
Line 606: Line 607:
Hoare S, Copland JA, Wood TG, Jeng YJ, Izban MG, Soloff MS.
Hoare S, Copland JA, Wood TG, Jeng YJ, Izban MG, Soloff MS.
PMID: 10218980</Comment>
PMID: 10218980</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GABPB2 | GA binding protein transcription facto..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GABPB2 | GA binding protein transcription facto..."/>
-
     <Graphics CenterX="683.6666666666671" CenterY="903.6666666666671" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="683.6666666666671" CenterY="903.6666666666671" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2553" />
+
     <Xref Database="Entrez Gene" ID="2553"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCD" GraphId="e1522" Type="GeneProduct" GroupRef="ff3b9">
   <DataNode TextLabel="PRKCD" GraphId="e1522" Type="GeneProduct" GroupRef="ff3b9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCD | protein kinase C delta" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCD | protein kinase C delta"/>
-
     <Graphics CenterX="1191.9999999999998" CenterY="386.92517006802734" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1191.9999999999998" CenterY="386.92517006802734" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5580" />
+
     <Xref Database="Entrez Gene" ID="5580"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SP1" GraphId="e15f2" Type="GeneProduct" GroupRef="ab773">
   <DataNode TextLabel="SP1" GraphId="e15f2" Type="GeneProduct" GroupRef="ab773">
Line 623: Line 624:
PMID: 11255234</Comment>
PMID: 11255234</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="SP1 | Sp1 transcription factor" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="SP1 | Sp1 transcription factor"/>
-
     <Graphics CenterX="786.0000000000005" CenterY="822.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="786.0000000000005" CenterY="822.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6667" />
+
     <Xref Database="Entrez Gene" ID="6667"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GABPA" GraphId="e2a34" Type="GeneProduct" GroupRef="e5925">
   <DataNode TextLabel="GABPA" GraphId="e2a34" Type="GeneProduct" GroupRef="e5925">
Line 632: Line 633:
Hoare S, Copland JA, Wood TG, Jeng YJ, Izban MG, Soloff MS.
Hoare S, Copland JA, Wood TG, Jeng YJ, Izban MG, Soloff MS.
PMID: 10218980</Comment>
PMID: 10218980</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GABPA | GA binding protein transcription factor..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GABPA | GA binding protein transcription factor..."/>
-
     <Graphics CenterX="683.6666666666671" CenterY="883.6666666666671" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="683.6666666666671" CenterY="883.6666666666671" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2551" />
+
     <Xref Database="Entrez Gene" ID="2551"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY6" GraphId="e2cd8" Type="GeneProduct">
   <DataNode TextLabel="ADCY6" GraphId="e2cd8" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY6 | adenylate cyclase 6" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY6 | adenylate cyclase 6"/>
-
     <Graphics CenterX="318.66666666666663" CenterY="692.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="318.66666666666663" CenterY="692.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="112" />
+
     <Xref Database="Entrez Gene" ID="112"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GUCA2A" GraphId="e38cf" Type="GeneProduct" GroupRef="f0a9f">
   <DataNode TextLabel="GUCA2A" GraphId="e38cf" Type="GeneProduct" GroupRef="f0a9f">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCA2A | guanylate cyclase activator 2A (guanyl..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCA2A | guanylate cyclase activator 2A (guanyl..."/>
-
     <Graphics CenterX="523.3333333333334" CenterY="100.0" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="523.3333333333334" CenterY="100.0" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2980" />
+
     <Xref Database="Entrez Gene" ID="2980"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ITPR1" GraphId="e3f4b" Type="GeneProduct" GroupRef="a15ef">
   <DataNode TextLabel="ITPR1" GraphId="e3f4b" Type="GeneProduct" GroupRef="a15ef">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITPR1 | inositol 145-triphosphate receptor t..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITPR1 | inositol 145-triphosphate receptor t..."/>
-
     <Graphics CenterX="646.3333333333333" CenterY="304.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="646.3333333333333" CenterY="304.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3708" />
+
     <Xref Database="Entrez Gene" ID="3708"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CAMK2B" GraphId="e501a" Type="GeneProduct" GroupRef="da70b">
   <DataNode TextLabel="CAMK2B" GraphId="e501a" Type="GeneProduct" GroupRef="da70b">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2B | calcium/calmodulin-dependent protein k..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2B | calcium/calmodulin-dependent protein k..."/>
-
     <Graphics CenterX="1175.9999999999998" CenterY="630.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1175.9999999999998" CenterY="630.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="816" />
+
     <Xref Database="Entrez Gene" ID="816"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CRHR1" GraphId="e52b6" Type="GeneProduct">
   <DataNode TextLabel="CRHR1" GraphId="e52b6" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CRHR1 | corticotropin releasing hormone recepto..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CRHR1 | corticotropin releasing hormone recepto..."/>
-
     <Graphics CenterX="330.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="330.0" CenterY="160.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1394" />
+
     <Xref Database="Entrez Gene" ID="1394"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RLN1" GraphId="e56e3" Type="GeneProduct">
   <DataNode TextLabel="RLN1" GraphId="e56e3" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RLN1 | relaxin 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RLN1 | relaxin 1"/>
-
     <Graphics CenterX="96.66666666666667" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="96.66666666666667" CenterY="102.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6013" />
+
     <Xref Database="Entrez Gene" ID="6013"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PDE4D" GraphId="e5714" Type="GeneProduct" GroupRef="edaa9">
   <DataNode TextLabel="PDE4D" GraphId="e5714" Type="GeneProduct" GroupRef="edaa9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE4D | phosphodiesterase 4D cAMP-specific (ph..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE4D | phosphodiesterase 4D cAMP-specific (ph..."/>
-
     <Graphics CenterX="72.33333333333334" CenterY="380.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="72.33333333333334" CenterY="380.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5144" />
+
     <Xref Database="Entrez Gene" ID="5144"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GRK6" GraphId="e67cb" Type="GeneProduct" GroupRef="b01f5">
   <DataNode TextLabel="GRK6" GraphId="e67cb" Type="GeneProduct" GroupRef="b01f5">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK6 | G protein-coupled receptor kinase 6" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRK6 | G protein-coupled receptor kinase 6"/>
-
     <Graphics CenterX="92.33333333333326" CenterY="246.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="92.33333333333326" CenterY="246.66666666666663" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2870" />
+
     <Xref Database="Entrez Gene" ID="2870"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ETS2" GraphId="e7514" Type="GeneProduct" GroupRef="ab773">
   <DataNode TextLabel="ETS2" GraphId="e7514" Type="GeneProduct" GroupRef="ab773">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ETS2 | v-ets erythroblastosis virus E26 oncogen..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ETS2 | v-ets erythroblastosis virus E26 oncogen..."/>
-
     <Graphics CenterX="786.0000000000005" CenterY="782.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="786.0000000000005" CenterY="782.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2114" />
+
     <Xref Database="Entrez Gene" ID="2114"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATF3" GraphId="e780b" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="ATF3" GraphId="e780b" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF3 | activating transcription factor 3" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF3 | activating transcription factor 3"/>
-
     <Graphics CenterX="63.0" CenterY="612.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="63.0" CenterY="612.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="467" />
+
     <Xref Database="Entrez Gene" ID="467"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY4" GraphId="e7e21" Type="GeneProduct">
   <DataNode TextLabel="ADCY4" GraphId="e7e21" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">There is no SwissProt entry for a full-length sequence in mouse.  This EST is from the Affymetrix Murine6500 chip.</Comment>
     <Comment Source="GenMAPP remarks">There is no SwissProt entry for a full-length sequence in mouse.  This EST is from the Affymetrix Murine6500 chip.</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY4 | adenylate cyclase 4" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY4 | adenylate cyclase 4"/>
-
     <Graphics CenterX="250.0" CenterY="752.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="250.0" CenterY="752.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="196883" />
+
     <Xref Database="Entrez Gene" ID="196883"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLCD1" GraphId="e84a9" Type="GeneProduct" GroupRef="f2693">
   <DataNode TextLabel="PLCD1" GraphId="e84a9" Type="GeneProduct" GroupRef="f2693">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCD1 | phospholipase C delta 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCD1 | phospholipase C delta 1"/>
-
     <Graphics CenterX="1271.9999999999998" CenterY="630.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1271.9999999999998" CenterY="630.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5333" />
+
     <Xref Database="Entrez Gene" ID="5333"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS4" GraphId="e86c9" Type="GeneProduct">
   <DataNode TextLabel="RGS4" GraphId="e86c9" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS4 | regulator of G-protein signalling 4" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS4 | regulator of G-protein signalling 4"/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="213.00000000000034" Width="60.0" Height="20.00000000000003" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="213.00000000000034" Width="60.0" Height="20.00000000000003" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5999" />
+
     <Xref Database="Entrez Gene" ID="5999"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS14" GraphId="e962f" Type="GeneProduct">
   <DataNode TextLabel="RGS14" GraphId="e962f" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS14 | regulator of G-protein signalling 14" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS14 | regulator of G-protein signalling 14"/>
-
     <Graphics CenterX="1258.6666666666663" CenterY="193.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1258.6666666666663" CenterY="193.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10636" />
+
     <Xref Database="Entrez Gene" ID="10636"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SLC8A1" GraphId="e9971" Type="GeneProduct">
   <DataNode TextLabel="SLC8A1" GraphId="e9971" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="SLC8A1 | solute carrier family 8 (sodium/calciu..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="SLC8A1 | solute carrier family 8 (sodium/calciu..."/>
-
     <Graphics CenterX="1058.0" CenterY="158.99999999999997" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1058.0" CenterY="158.99999999999997" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6546" />
+
     <Xref Database="Entrez Gene" ID="6546"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GUCA2B" GraphId="ea7ba" Type="GeneProduct" GroupRef="f0a9f">
   <DataNode TextLabel="GUCA2B" GraphId="ea7ba" Type="GeneProduct" GroupRef="f0a9f">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCA2B | guanylate cyclase activator 2B (urogua..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCA2B | guanylate cyclase activator 2B (urogua..."/>
-
     <Graphics CenterX="523.3333333333334" CenterY="120.0" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="523.3333333333334" CenterY="120.0" Width="60.85014666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2981" />
+
     <Xref Database="Entrez Gene" ID="2981"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ARRB1" GraphId="eb47a" Type="GeneProduct" GroupRef="b01f5">
   <DataNode TextLabel="ARRB1" GraphId="eb47a" Type="GeneProduct" GroupRef="b01f5">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB1 | arrestin beta 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB1 | arrestin beta 1"/>
-
     <Graphics CenterX="92.33333333333326" CenterY="266.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="92.33333333333326" CenterY="266.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="408" />
+
     <Xref Database="Entrez Gene" ID="408"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GJA1" GraphId="ebcb9" Type="GeneProduct" GroupRef="e60e9">
   <DataNode TextLabel="GJA1" GraphId="ebcb9" Type="GeneProduct" GroupRef="e60e9">
Line 727: Line 728:
Sladek SM, Westerhausen-Larson A, Roberts JM.
Sladek SM, Westerhausen-Larson A, Roberts JM.
PMID: 10377025</Comment>
PMID: 10377025</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GJA1 | gap junction protein alpha 1 43kDa (co..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GJA1 | gap junction protein alpha 1 43kDa (co..."/>
-
     <Graphics CenterX="946.0000000000005" CenterY="837.3333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="946.0000000000005" CenterY="837.3333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2697" />
+
     <Xref Database="Entrez Gene" ID="2697"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ARRB1" GraphId="ec135" Type="GeneProduct" GroupRef="e2890">
   <DataNode TextLabel="ARRB1" GraphId="ec135" Type="GeneProduct" GroupRef="e2890">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB1 | arrestin beta 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARRB1 | arrestin beta 1"/>
-
     <Graphics CenterX="899.3333333333333" CenterY="198.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="899.3333333333333" CenterY="198.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="408" />
+
     <Xref Database="Entrez Gene" ID="408"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="YWHAG" GraphId="eca01" Type="GeneProduct" GroupRef="a9e43">
   <DataNode TextLabel="YWHAG" GraphId="eca01" Type="GeneProduct" GroupRef="a9e43">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAG | tyrosine 3-monooxygenase/tryptophan 5-m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAG | tyrosine 3-monooxygenase/tryptophan 5-m..."/>
-
     <Graphics CenterX="1196.6138735420502" CenterY="546.0527931246163" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1196.6138735420502" CenterY="546.0527931246163" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="7532" />
+
     <Xref Database="Entrez Gene" ID="7532"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CACNB3" GraphId="ed286" Type="GeneProduct">
   <DataNode TextLabel="CACNB3" GraphId="ed286" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CACNB3 | calcium channel voltage-dependent be..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CACNB3 | calcium channel voltage-dependent be..."/>
-
     <Graphics CenterX="980.7360343769183" CenterY="158.99999999999957" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="980.7360343769183" CenterY="158.99999999999957" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="784" />
+
     <Xref Database="Entrez Gene" ID="784"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CMKOR1" GraphId="ed3c1" Type="GeneProduct" GroupRef="aa636">
   <DataNode TextLabel="CMKOR1" GraphId="ed3c1" Type="GeneProduct" GroupRef="aa636">
     <Comment Source="GenMAPP remarks">PMID: 10614663</Comment>
     <Comment Source="GenMAPP remarks">PMID: 10614663</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CMKOR1 | chemokine orphan receptor 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CMKOR1 | chemokine orphan receptor 1"/>
-
     <Graphics CenterX="173.33333333333334" CenterY="170.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="173.33333333333334" CenterY="170.0" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="57007" />
+
     <Xref Database="Entrez Gene" ID="57007"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IGFBP1" GraphId="ee38a" Type="GeneProduct">
   <DataNode TextLabel="IGFBP1" GraphId="ee38a" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP1 | insulin-like growth factor binding pro..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP1 | insulin-like growth factor binding pro..."/>
-
     <Graphics CenterX="160.0" CenterY="692.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="160.0" CenterY="692.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3484" />
+
     <Xref Database="Entrez Gene" ID="3484"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PKIG" GraphId="eeee6" Type="GeneProduct" GroupRef="b262c">
   <DataNode TextLabel="PKIG" GraphId="eeee6" Type="GeneProduct" GroupRef="b262c">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PKIG | protein kinase (cAMP-dependent catalyti..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PKIG | protein kinase (cAMP-dependent catalyti..."/>
-
     <Graphics CenterX="107.66666666666674" CenterY="515.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="107.66666666666674" CenterY="515.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="11142" />
+
     <Xref Database="Entrez Gene" ID="11142"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PDE4B" GraphId="eefb4" Type="GeneProduct" GroupRef="edaa9">
   <DataNode TextLabel="PDE4B" GraphId="eefb4" Type="GeneProduct" GroupRef="edaa9">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE4B | phosphodiesterase 4B cAMP-specific (ph..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE4B | phosphodiesterase 4B cAMP-specific (ph..."/>
-
     <Graphics CenterX="72.33333333333334" CenterY="360.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="72.33333333333334" CenterY="360.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5142" />
+
     <Xref Database="Entrez Gene" ID="5142"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNGT1" GraphId="ef0ed" Type="GeneProduct">
   <DataNode TextLabel="GNGT1" GraphId="ef0ed" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNGT1 | guanine nucleotide binding protein (G p..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNGT1 | guanine nucleotide binding protein (G p..."/>
-
     <Graphics CenterX="472.33333333333337" CenterY="687.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="472.33333333333337" CenterY="687.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2792" />
+
     <Xref Database="Entrez Gene" ID="2792"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PKIA" GraphId="f11bd" Type="GeneProduct" GroupRef="b262c">
   <DataNode TextLabel="PKIA" GraphId="f11bd" Type="GeneProduct" GroupRef="b262c">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PKIA | protein kinase (cAMP-dependent catalyti..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PKIA | protein kinase (cAMP-dependent catalyti..."/>
-
     <Graphics CenterX="107.66666666666674" CenterY="475.66666666666674" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="107.66666666666674" CenterY="475.66666666666674" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5569" />
+
     <Xref Database="Entrez Gene" ID="5569"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="YWHAQ" GraphId="f12df" Type="GeneProduct" GroupRef="a9e43">
   <DataNode TextLabel="YWHAQ" GraphId="f12df" Type="GeneProduct" GroupRef="a9e43">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-m..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-m..."/>
-
     <Graphics CenterX="1256.61387354205" CenterY="506.66666666666663" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1256.61387354205" CenterY="506.66666666666663" Width="60.00000000000001" Height="20.000000000000025" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10971" />
+
     <Xref Database="Entrez Gene" ID="10971"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Cyclic GMP" GraphId="f43ae" Type="Metabolite">
   <DataNode TextLabel="Cyclic GMP" GraphId="f43ae" Type="Metabolite">
-
     <Graphics CenterX="532.5" CenterY="333.0" Width="63.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="532.5" CenterY="333.0" Width="63.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0001314" />
+
     <Xref Database="HMDB" ID="HMDB0001314"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CREB3" GraphId="f4dd8" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="CREB3" GraphId="f4dd8" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CREB3 | cAMP responsive element binding protein..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CREB3 | cAMP responsive element binding protein..."/>
-
     <Graphics CenterX="132.33333333333331" CenterY="592.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="132.33333333333331" CenterY="592.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="10488" />
+
     <Xref Database="Entrez Gene" ID="10488"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ACTC" GraphId="f4f84" Type="GeneProduct" GroupRef="b38f8">
   <DataNode TextLabel="ACTC" GraphId="f4f84" Type="GeneProduct" GroupRef="b38f8">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTC | actin alpha cardiac muscle" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTC | actin alpha cardiac muscle"/>
-
     <Graphics CenterX="643.3333333333334" CenterY="651.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="643.3333333333334" CenterY="651.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="70" />
+
     <Xref Database="Entrez Gene" ID="70"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADP" GraphId="f545b" Type="Metabolite">
   <DataNode TextLabel="ADP" GraphId="f545b" Type="Metabolite">
-
     <Graphics CenterX="947.0" CenterY="676.6666666666665" Width="33.333333333333336" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="947.0" CenterY="676.6666666666665" Width="33.333333333333336" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="CAS" ID="58-64-0" />
+
     <Xref Database="CAS" ID="58-64-0"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="IGFBP3" GraphId="f6872" Type="GeneProduct">
   <DataNode TextLabel="IGFBP3" GraphId="f6872" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">Relaxin is a member of the Insulin Growth Factor family of proteins.  IGFBP-3 binds IGFII preferentially. (SwissProt).</Comment>
     <Comment Source="GenMAPP remarks">Relaxin is a member of the Insulin Growth Factor family of proteins.  IGFBP-3 binds IGFII preferentially. (SwissProt).</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP3 | insulin-like growth factor binding pro..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="IGFBP3 | insulin-like growth factor binding pro..."/>
-
     <Graphics CenterX="160.0" CenterY="732.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="160.0" CenterY="732.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3486" />
+
     <Xref Database="Entrez Gene" ID="3486"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLCG1" GraphId="f6ab9" Type="GeneProduct" GroupRef="f2693">
   <DataNode TextLabel="PLCG1" GraphId="f6ab9" Type="GeneProduct" GroupRef="f2693">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCG1 | phospholipase C gamma 1" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCG1 | phospholipase C gamma 1"/>
-
     <Graphics CenterX="1271.9999999999998" CenterY="650.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1271.9999999999998" CenterY="650.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5335" />
+
     <Xref Database="Entrez Gene" ID="5335"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNAS" GraphId="f6b05" Type="GeneProduct">
   <DataNode TextLabel="GNAS" GraphId="f6b05" Type="GeneProduct">
-
     <Comment Source="GenMAPP remarks"></Comment>
+
     <Comment Source="GenMAPP remarks"/>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAS | GNAS complex locus" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAS | GNAS complex locus"/>
-
     <Graphics CenterX="203.33333333333334" CenterY="286.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="203.33333333333334" CenterY="286.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2778" />
+
     <Xref Database="Entrez Gene" ID="2778"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MAFF" GraphId="f6b0e" Type="GeneProduct" GroupRef="c509b">
   <DataNode TextLabel="MAFF" GraphId="f6b0e" Type="GeneProduct" GroupRef="c509b">
     <Comment Source="GenMAPP remarks">OMIM: Inoue et al. (1994) demonstrated that the US-2 element in the promoter of the human oxytocin receptor gene (OXTR; 167055) binds specifically nuclear proteins from human myometrium at parturition. Using the US-2 element in a yeast 1-hybrid system to screen a human myometrium cDNA library, Kimura et al. (1999) isolated a full-length cDNA encoding the homolog of chicken MafF. Human MAFF encodes a deduced 164-amino acid protein with a predicted molecular mass of 17.8 kD. Like other small MAF proteins (e.g., MAFG, 602020), it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. Northern blot analysis showed a strong 2.6-kb signal in mRNA from term myometrium and from kidney, but not from nonpregnant myometrium. The MAFF protein is also preferentially expressed in term myometrium. The authors concluded that MAFF plays a role in OXTR gene upregulation at term.</Comment>
     <Comment Source="GenMAPP remarks">OMIM: Inoue et al. (1994) demonstrated that the US-2 element in the promoter of the human oxytocin receptor gene (OXTR; 167055) binds specifically nuclear proteins from human myometrium at parturition. Using the US-2 element in a yeast 1-hybrid system to screen a human myometrium cDNA library, Kimura et al. (1999) isolated a full-length cDNA encoding the homolog of chicken MafF. Human MAFF encodes a deduced 164-amino acid protein with a predicted molecular mass of 17.8 kD. Like other small MAF proteins (e.g., MAFG, 602020), it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. Northern blot analysis showed a strong 2.6-kb signal in mRNA from term myometrium and from kidney, but not from nonpregnant myometrium. The MAFF protein is also preferentially expressed in term myometrium. The authors concluded that MAFF plays a role in OXTR gene upregulation at term.</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAFF | v-maf musculoaponeurotic fibrosarcoma on..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAFF | v-maf musculoaponeurotic fibrosarcoma on..."/>
-
     <Graphics CenterX="788.0000000000005" CenterY="880.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="788.0000000000005" CenterY="880.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="23764" />
+
     <Xref Database="Entrez Gene" ID="23764"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKACA" GraphId="f71ef" Type="GeneProduct" GroupRef="cb90f">
   <DataNode TextLabel="PRKACA" GraphId="f71ef" Type="GeneProduct" GroupRef="cb90f">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKACA | protein kinase cAMP-dependent cataly..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKACA | protein kinase cAMP-dependent cataly..."/>
-
     <Graphics CenterX="231.33333333333331" CenterY="526.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="231.33333333333331" CenterY="526.0" Width="71.16953333333332" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5566" />
+
     <Xref Database="Entrez Gene" ID="5566"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CALM3" GraphId="f76a2" Type="GeneProduct" GroupRef="ac6cc">
   <DataNode TextLabel="CALM3" GraphId="f76a2" Type="GeneProduct" GroupRef="ac6cc">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALM3 | calmodulin 3 (phosphorylase kinase del..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALM3 | calmodulin 3 (phosphorylase kinase del..."/>
-
     <Graphics CenterX="813.3333333333333" CenterY="475.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="813.3333333333333" CenterY="475.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="808" />
+
     <Xref Database="Entrez Gene" ID="808"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATF2" GraphId="f86c8" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="ATF2" GraphId="f86c8" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF2 | activating transcription factor 2" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ATF2 | activating transcription factor 2"/>
-
     <Graphics CenterX="63.0" CenterY="592.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="63.0" CenterY="592.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1386" />
+
     <Xref Database="Entrez Gene" ID="1386"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNG4" GraphId="f9223" Type="GeneProduct">
   <DataNode TextLabel="GNG4" GraphId="f9223" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG4 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG4 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="472.33333333333337" CenterY="747.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="472.33333333333337" CenterY="747.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2786" />
+
     <Xref Database="Entrez Gene" ID="2786"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CALM2" GraphId="f9e16" Type="GeneProduct" GroupRef="ac6cc">
   <DataNode TextLabel="CALM2" GraphId="f9e16" Type="GeneProduct" GroupRef="ac6cc">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALM2 | calmodulin 2 (phosphorylase kinase del..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALM2 | calmodulin 2 (phosphorylase kinase del..."/>
-
     <Graphics CenterX="813.3333333333333" CenterY="455.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="813.3333333333333" CenterY="455.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="805" />
+
     <Xref Database="Entrez Gene" ID="805"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ADCY9" GraphId="f9e74" Type="GeneProduct">
   <DataNode TextLabel="ADCY9" GraphId="f9e74" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY9 | adenylate cyclase 9" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY9 | adenylate cyclase 9"/>
-
     <Graphics CenterX="318.66666666666663" CenterY="752.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="318.66666666666663" CenterY="752.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="115" />
+
     <Xref Database="Entrez Gene" ID="115"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CALM1" GraphId="f9fd8" Type="GeneProduct" GroupRef="ac6cc">
   <DataNode TextLabel="CALM1" GraphId="f9fd8" Type="GeneProduct" GroupRef="ac6cc">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALM1 | calmodulin 1 (phosphorylase kinase del..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALM1 | calmodulin 1 (phosphorylase kinase del..."/>
-
     <Graphics CenterX="813.3333333333333" CenterY="435.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="813.3333333333333" CenterY="435.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="801" />
+
     <Xref Database="Entrez Gene" ID="801"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ACTA1" GraphId="fa3cd" Type="GeneProduct" GroupRef="b38f8">
   <DataNode TextLabel="ACTA1" GraphId="fa3cd" Type="GeneProduct" GroupRef="b38f8">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTA1 | actin alpha 1 skeletal muscle" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ACTA1 | actin alpha 1 skeletal muscle"/>
-
     <Graphics CenterX="643.3333333333334" CenterY="591.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="643.3333333333334" CenterY="591.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="58" />
+
     <Xref Database="Entrez Gene" ID="58"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNB1" GraphId="fa742" Type="GeneProduct">
   <DataNode TextLabel="GNB1" GraphId="fa742" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB1 | guanine nucleotide binding protein (G pr..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB1 | guanine nucleotide binding protein (G pr..."/>
-
     <Graphics CenterX="406.66666666666663" CenterY="687.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="406.66666666666663" CenterY="687.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2782" />
+
     <Xref Database="Entrez Gene" ID="2782"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MYL2" GraphId="faa5d" Type="GeneProduct" GroupRef="e8d60">
   <DataNode TextLabel="MYL2" GraphId="faa5d" Type="GeneProduct" GroupRef="e8d60">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYL2 | myosin light polypeptide 2 regulatory..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYL2 | myosin light polypeptide 2 regulatory..."/>
-
     <Graphics CenterX="933.6666666666666" CenterY="594.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="933.6666666666666" CenterY="594.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="4633" />
+
     <Xref Database="Entrez Gene" ID="4633"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS3" GraphId="fae78" Type="GeneProduct">
   <DataNode TextLabel="RGS3" GraphId="fae78" Type="GeneProduct">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS3 | regulator of G-protein signalling 3" />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="RGS3 | regulator of G-protein signalling 3"/>
-
     <Graphics CenterX="1183.9999999999998" CenterY="193.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1183.9999999999998" CenterY="193.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5998" />
+
     <Xref Database="Entrez Gene" ID="5998"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ITPR2" GraphId="fb14e" Type="GeneProduct" GroupRef="a15ef">
   <DataNode TextLabel="ITPR2" GraphId="fb14e" Type="GeneProduct" GroupRef="a15ef">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITPR2 | inositol 145-triphosphate receptor t..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITPR2 | inositol 145-triphosphate receptor t..."/>
-
     <Graphics CenterX="646.3333333333333" CenterY="324.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="646.3333333333333" CenterY="324.33333333333337" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="3709" />
+
     <Xref Database="Entrez Gene" ID="3709"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLCB3" GraphId="fb3ea" Type="GeneProduct" GroupRef="f2693">
   <DataNode TextLabel="PLCB3" GraphId="fb3ea" Type="GeneProduct" GroupRef="f2693">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCB3 | phospholipase C beta 3 (phosphatidylin..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCB3 | phospholipase C beta 3 (phosphatidylin..."/>
-
     <Graphics CenterX="1271.9999999999998" CenterY="609.9999999999999" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1271.9999999999998" CenterY="609.9999999999999" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5331" />
+
     <Xref Database="Entrez Gene" ID="5331"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ATP" GraphId="fc33b" Type="Metabolite">
   <DataNode TextLabel="ATP" GraphId="fc33b" Type="Metabolite">
-
     <Graphics CenterX="927.6666666666666" CenterY="646.3333333333334" Width="31.333333333333332" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="927.6666666666666" CenterY="646.3333333333334" Width="31.333333333333332" Height="16.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="CAS" ID="1927-31-7" />
+
     <Xref Database="CAS" ID="1927-31-7"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CAMK2A" GraphId="fcddf" Type="GeneProduct" GroupRef="da70b">
   <DataNode TextLabel="CAMK2A" GraphId="fcddf" Type="GeneProduct" GroupRef="da70b">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2A | calcium/calmodulin-dependent protein k..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAMK2A | calcium/calmodulin-dependent protein k..."/>
-
     <Graphics CenterX="1175.9999999999998" CenterY="609.9999999999999" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="1175.9999999999998" CenterY="609.9999999999999" Width="65.23876666666666" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="815" />
+
     <Xref Database="Entrez Gene" ID="815"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NFKB1" GraphId="fd09c" Type="GeneProduct" GroupRef="ab773">
   <DataNode TextLabel="NFKB1" GraphId="fd09c" Type="GeneProduct" GroupRef="ab773">
Line 901: Line 902:
Echetebu CO, Ali M, Izban MG, MacKay L, Garfield RE. PMID: 10421804</Comment>
Echetebu CO, Ali M, Izban MG, MacKay L, Garfield RE. PMID: 10421804</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="NFKB1 | nuclear factor of kappa light polypepti..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="NFKB1 | nuclear factor of kappa light polypepti..."/>
-
     <Graphics CenterX="786.0000000000005" CenterY="802.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="786.0000000000005" CenterY="802.6666666666671" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="4790" />
+
     <Xref Database="Entrez Gene" ID="4790"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Cyclic AMP" GraphId="fd566" Type="Metabolite">
   <DataNode TextLabel="Cyclic AMP" GraphId="fd566" Type="Metabolite">
-
     <Graphics CenterX="204.5" CenterY="370.0" Width="63.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="204.5" CenterY="370.0" Width="63.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="HMDB" ID="HMDB0000058" />
+
     <Xref Database="HMDB" ID="HMDB0000058"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CREB1" GraphId="fe4d9" Type="GeneProduct" GroupRef="d37aa">
   <DataNode TextLabel="CREB1" GraphId="fe4d9" Type="GeneProduct" GroupRef="d37aa">
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CREB1 | cAMP responsive element binding protein..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="CREB1 | cAMP responsive element binding protein..."/>
-
     <Graphics CenterX="132.33333333333331" CenterY="572.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="132.33333333333331" CenterY="572.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1385" />
+
     <Xref Database="Entrez Gene" ID="1385"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GUCY1A3" GraphId="ff2d6" Type="GeneProduct">
   <DataNode TextLabel="GUCY1A3" GraphId="ff2d6" Type="GeneProduct">
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
     <Comment Source="GenMAPP remarks">PMID: 11854458</Comment>
-
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCY1A3 | guanylate cyclase 1 soluble alpha 3..." />
+
     <Attribute Key="org.pathvisio.model.BackpageHead" Value="GUCY1A3 | guanylate cyclase 1 soluble alpha 3..."/>
-
     <Graphics CenterX="379.9999999999999" CenterY="345.3333333333332" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="379.9999999999999" CenterY="345.3333333333332" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="2982" />
+
     <Xref Database="Entrez Gene" ID="2982"/>
   </DataNode>
   </DataNode>
   <Interaction GraphId="a4805">
   <Interaction GraphId="a4805">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="740.0" Y="170.0" GraphRef="aa684" RelX="0.0" RelY="1.0" />
+
       <Point X="740.0" Y="170.0" GraphRef="aa684" RelX="0.0" RelY="1.0"/>
-
       <Point X="740.0" Y="210.0" GraphRef="cd799" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="740.0" Y="210.0" GraphRef="cd799" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.675" Shape="None" GraphId="b7b89" />
+
       <Anchor Position="0.675" Shape="None" GraphId="b7b89"/>
-
       <Anchor Position="0.5" Shape="None" GraphId="fdd58" />
+
       <Anchor Position="0.5" Shape="None" GraphId="fdd58"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="a4ede">
   <Interaction GraphId="a4ede">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="1053.3333333333333" Y="573.3333333333334" GraphRef="beb0c" RelX="0.0" RelY="1.0" />
+
       <Point X="1053.3333333333333" Y="573.3333333333334" GraphRef="beb0c" RelX="0.0" RelY="1.0"/>
-
       <Point X="986.945980658507" Y="673.4849057132226" GraphRef="af380" RelX="0.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="986.945980658507" Y="673.4849057132226" GraphRef="af380" RelX="0.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="a827d">
   <Interaction GraphId="a827d">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="826.5930215022071" Y="849.061869599506" GraphRef="ac9ef" RelX="0.0" RelY="0.0" />
+
       <Point X="826.5930215022071" Y="849.061869599506" GraphRef="ac9ef" RelX="0.0" RelY="0.0"/>
-
       <Point X="788.0000000000005" Y="858.6666666666671" GraphRef="e239d" RelX="0.0" RelY="-1.0" />
+
       <Point X="788.0000000000005" Y="858.6666666666671" GraphRef="e239d" RelX="0.0" RelY="-1.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="a8331">
   <Interaction GraphId="a8331">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="1043.25" Y="135.66666666666669" GraphRef="cff6d" RelX="0.0" RelY="1.0" />
+
       <Point X="1043.25" Y="135.66666666666669" GraphRef="cff6d" RelX="0.0" RelY="1.0"/>
-
       <Point X="1018.3333333333334" Y="239.66666666666666" GraphRef="d08b2" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="1018.3333333333334" Y="239.66666666666666" GraphRef="d08b2" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.23440763951059396" Shape="None" GraphId="d13bb" />
+
       <Anchor Position="0.23440763951059396" Shape="None" GraphId="d13bb"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="a8572">
   <Interaction GraphId="a8572">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="420.0" Y="112.0" GraphRef="e04fa" RelX="0.0" RelY="1.0" />
+
       <Point X="420.0" Y="112.0" GraphRef="e04fa" RelX="0.0" RelY="1.0"/>
-
       <Point X="451.6666666666667" Y="150.0" GraphRef="a6668" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="451.6666666666667" Y="150.0" GraphRef="a6668" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="a8e79">
   <Interaction GraphId="a8e79">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="35.66666666666667" Y="125.33333333333331" GraphRef="fbff2" RelX="0.0" RelY="-1.0" />
+
       <Point X="35.66666666666667" Y="125.33333333333331" GraphRef="fbff2" RelX="0.0" RelY="-1.0"/>
-
       <Point X="36.333333333333336" Y="84.33333333333333" GraphRef="db7e8" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="36.333333333333336" Y="84.33333333333333" GraphRef="db7e8" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="abf8f">
   <Interaction GraphId="abf8f">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="278.9181" Y="532.0" GraphRef="a99ad" RelX="1.0" RelY="0.5" />
+
       <Point X="278.9181" Y="532.0" GraphRef="a99ad" RelX="1.0" RelY="0.5"/>
-
       <Point X="832.0" Y="536.3333333333334" GraphRef="bb691" RelX="-1.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="832.0" Y="536.3333333333334" GraphRef="bb691" RelX="-1.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="aca88">
   <Interaction GraphId="aca88">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="173.33333333333334" Y="111.0" GraphRef="d2491" RelX="0.0" RelY="1.0" />
+
       <Point X="173.33333333333334" Y="111.0" GraphRef="d2491" RelX="0.0" RelY="1.0"/>
-
       <Point X="173.33333333333334" Y="132.0" GraphRef="ef2b7" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="173.33333333333334" Y="132.0" GraphRef="ef2b7" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="acb7e">
   <Interaction GraphId="acb7e">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="1058.0" Y="148.99999999999997" GraphRef="e9971" RelX="0.0" RelY="-1.0" />
+
       <Point X="1058.0" Y="148.99999999999997" GraphRef="e9971" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1037.4093429821944" Y="160.04506117576844" GraphRef="d13bb" RelX="0.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1037.4093429821944" Y="160.04506117576844" GraphRef="d13bb" RelX="0.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="acde8">
   <Interaction GraphId="acde8">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="1053.6666666666665" Y="515.1666666666667" GraphRef="cd392" RelX="0.0" RelY="1.0" />
+
       <Point X="1053.6666666666665" Y="515.1666666666667" GraphRef="cd392" RelX="0.0" RelY="1.0"/>
-
       <Point X="1053.3333333333333" Y="553.3333333333334" GraphRef="beb0c" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="1053.3333333333333" Y="553.3333333333334" GraphRef="beb0c" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ad42e">
   <Interaction GraphId="ad42e">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0099">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0099">
-
       <Point X="149.66666666666674" Y="495.6666666666667" GraphRef="a753e" RelX="1.0" RelY="0.0" />
+
       <Point X="149.66666666666674" Y="495.6666666666667" GraphRef="a753e" RelX="1.0" RelY="0.0"/>
-
       <Point X="183.74856666666665" Y="496.0" GraphRef="a99ad" RelX="-1.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="183.74856666666665" Y="496.0" GraphRef="a99ad" RelX="-1.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ade7e">
   <Interaction GraphId="ade7e">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="832.3333333333333" Y="493.33333333333337" GraphRef="e3f7e" RelX="0.5" RelY="1.0" />
+
       <Point X="832.3333333333333" Y="493.33333333333337" GraphRef="e3f7e" RelX="0.5" RelY="1.0"/>
-
       <Point X="847.0" Y="526.3333333333334" GraphRef="bb691" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="847.0" Y="526.3333333333334" GraphRef="bb691" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.6214285714285713" Shape="None" GraphId="b49da" />
+
       <Anchor Position="0.6214285714285713" Shape="None" GraphId="b49da"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b292c">
   <Interaction GraphId="b292c">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="994.0" Y="255.66666666666666" GraphRef="d08b2" RelX="0.0" RelY="1.0" />
+
       <Point X="994.0" Y="255.66666666666666" GraphRef="d08b2" RelX="0.0" RelY="1.0"/>
-
       <Point X="891.0" Y="396.33333333333337" GraphRef="a9089" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="891.0" Y="396.33333333333337" GraphRef="a9089" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b6e62">
   <Interaction GraphId="b6e62">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="740.3333333333335" Y="269.0" GraphRef="a9f40" RelX="0.0" RelY="1.0" />
+
       <Point X="740.3333333333335" Y="269.0" GraphRef="a9f40" RelX="0.0" RelY="1.0"/>
-
       <Point X="740.0" Y="313.8333333333333" GraphRef="f5571" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="740.0" Y="313.8333333333333" GraphRef="f5571" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.3570786982657362" Shape="None" GraphId="befed" />
+
       <Anchor Position="0.3570786982657362" Shape="None" GraphId="befed"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b75ab">
   <Interaction GraphId="b75ab">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="111.66666666666667" Y="180.0" GraphRef="db337" RelX="0.5" RelY="1.0" />
+
       <Point X="111.66666666666667" Y="180.0" GraphRef="db337" RelX="0.5" RelY="1.0"/>
-
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b837f">
   <Interaction GraphId="b837f">
     <Graphics ConnectorType="Elbow" ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ConnectorType="Elbow" ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="907.1666666666667" Y="403.16666666666674" GraphRef="a9089" RelX="1.0" RelY="0.0" />
+
       <Point X="907.1666666666667" Y="403.16666666666674" GraphRef="a9089" RelX="1.0" RelY="0.0"/>
-
       <Point X="1053.6666666666665" Y="496.16666666666674" GraphRef="cd392" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="1053.6666666666665" Y="496.16666666666674" GraphRef="cd392" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b83b3">
   <Interaction GraphId="b83b3">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
-
       <Point X="972.6397576911843" Y="655.2399441441369" GraphRef="e8430" RelX="0.0" RelY="0.0" />
+
       <Point X="972.6397576911843" Y="655.2399441441369" GraphRef="e8430" RelX="0.0" RelY="0.0"/>
-
       <Point X="947.0" Y="668.6666666666665" GraphRef="f545b" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="947.0" Y="668.6666666666665" GraphRef="f545b" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b8c11">
   <Interaction GraphId="b8c11">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="504.1207966666667" Y="138.0" GraphRef="ccf62" RelX="-0.5" RelY="1.0" />
+
       <Point X="504.1207966666667" Y="138.0" GraphRef="ccf62" RelX="-0.5" RelY="1.0"/>
-
       <Point X="481.6666666666667" Y="150.0" GraphRef="a6668" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="481.6666666666667" Y="150.0" GraphRef="a6668" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b933a">
   <Interaction GraphId="b933a">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="532.5" Y="343.0" GraphRef="f43ae" RelX="0.0" RelY="1.0" />
+
       <Point X="532.5" Y="343.0" GraphRef="f43ae" RelX="0.0" RelY="1.0"/>
-
       <Point X="404.3333333333333" Y="420.5" GraphRef="e771d" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="404.3333333333333" Y="420.5" GraphRef="e771d" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b9a19">
   <Interaction GraphId="b9a19">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="438.6666666666667" Y="476.6666666666667" GraphRef="ea44e" RelX="-1.0" RelY="0.0" />
+
       <Point X="438.6666666666667" Y="476.6666666666667" GraphRef="ea44e" RelX="-1.0" RelY="0.0"/>
-
       <Point X="374.9999999999999" Y="476.6666666666667" GraphRef="e57e1" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="374.9999999999999" Y="476.6666666666667" GraphRef="e57e1" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="b9be3">
   <Interaction GraphId="b9be3">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="96.66666666666667" Y="112.0" GraphRef="e56e3" RelX="0.0" RelY="1.0" />
+
       <Point X="96.66666666666667" Y="112.0" GraphRef="e56e3" RelX="0.0" RelY="1.0"/>
-
       <Point X="96.66666666666667" Y="132.0" GraphRef="c8ce4" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="96.66666666666667" Y="132.0" GraphRef="c8ce4" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="bbe03">
   <Interaction GraphId="bbe03">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="772.0" Y="293.1666666666667" GraphRef="b3b7b" RelX="0.0" RelY="1.0" />
+
       <Point X="772.0" Y="293.1666666666667" GraphRef="b3b7b" RelX="0.0" RelY="1.0"/>
-
       <Point X="773.1666666666667" Y="316.3333333333333" GraphRef="c4b6e" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="773.1666666666667" Y="316.3333333333333" GraphRef="c4b6e" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="bd0d1">
   <Interaction GraphId="bd0d1">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
-
       <Point X="625.0" Y="170.0" GraphRef="bb7d5" RelX="-0.5" RelY="1.0" />
+
       <Point X="625.0" Y="170.0" GraphRef="bb7d5" RelX="-0.5" RelY="1.0"/>
-
       <Point X="625.5" Y="195.0" GraphRef="cded0" RelX="0.0" RelY="-1.0" ArrowHead="TBar" />
+
       <Point X="625.5" Y="195.0" GraphRef="cded0" RelX="0.0" RelY="-1.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="be348">
   <Interaction GraphId="be348">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="767.8333333333335" Y="513.0" GraphRef="bc693" RelX="1.0" RelY="0.0" />
+
       <Point X="767.8333333333335" Y="513.0" GraphRef="bc693" RelX="1.0" RelY="0.0"/>
-
       <Point X="841.447619047619" Y="513.8404761904762" GraphRef="b49da" RelX="0.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="841.447619047619" Y="513.8404761904762" GraphRef="b49da" RelX="0.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="bee91">
   <Interaction GraphId="bee91">
     <Graphics ConnectorType="Curved" ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ConnectorType="Curved" ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="315.0" Y="170.0" GraphRef="e52b6" RelX="-0.5" RelY="1.0" />
+
       <Point X="315.0" Y="170.0" GraphRef="e52b6" RelX="-0.5" RelY="1.0"/>
-
       <Point X="259.1666666666667" Y="241.0" />
+
       <Point X="259.1666666666667" Y="241.0"/>
-
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c0bbf">
   <Interaction GraphId="c0bbf">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="793.3333333333335" Y="325.8333333333333" GraphRef="c4b6e" RelX="0.0" RelY="1.0" />
+
       <Point X="793.3333333333335" Y="325.8333333333333" GraphRef="c4b6e" RelX="0.0" RelY="1.0"/>
-
       <Point X="882.9166666666666" Y="396.33333333333337" GraphRef="a9089" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="882.9166666666666" Y="396.33333333333337" GraphRef="a9089" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c18dc">
   <Interaction GraphId="c18dc">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="740.0" Y="230.0" GraphRef="cd799" RelX="0.0" RelY="1.0" />
+
       <Point X="740.0" Y="230.0" GraphRef="cd799" RelX="0.0" RelY="1.0"/>
-
       <Point X="740.3333333333335" Y="253.0" GraphRef="a9f40" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="740.3333333333335" Y="253.0" GraphRef="a9f40" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c3524">
   <Interaction GraphId="c3524">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="110.33333333333334" Y="370.0" GraphRef="cc0c0" RelX="1.0" RelY="0.0" />
+
       <Point X="110.33333333333334" Y="370.0" GraphRef="cc0c0" RelX="1.0" RelY="0.0"/>
-
       <Point X="173.0" Y="370.0" GraphRef="fd566" RelX="-1.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="173.0" Y="370.0" GraphRef="fd566" RelX="-1.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c413f">
   <Interaction GraphId="c413f">
     <Graphics ConnectorType="Curved" ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ConnectorType="Curved" ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="96.66666666666667" Y="188.0" GraphRef="c8ce4" RelX="0.0" RelY="1.0" />
+
       <Point X="96.66666666666667" Y="188.0" GraphRef="c8ce4" RelX="0.0" RelY="1.0"/>
-
       <Point X="35.66666666666667" Y="141.33333333333331" GraphRef="fbff2" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="35.66666666666667" Y="141.33333333333331" GraphRef="fbff2" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c64a0">
   <Interaction GraphId="c64a0">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="413.33333333333326" Y="345.3333333333332" GraphRef="ff2d6" RelX="1.0" RelY="0.0" />
+
       <Point X="413.33333333333326" Y="345.3333333333332" GraphRef="ff2d6" RelX="1.0" RelY="0.0"/>
-
       <Point X="501.0" Y="333.0" GraphRef="f43ae" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="501.0" Y="333.0" GraphRef="f43ae" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c6fe1">
   <Interaction GraphId="c6fe1">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
-
       <Point X="682.3333333333334" Y="442.33333333333326" GraphRef="fa4f4" RelX="1.0" RelY="0.0" />
+
       <Point X="682.3333333333334" Y="442.33333333333326" GraphRef="fa4f4" RelX="1.0" RelY="0.0"/>
-
       <Point X="737.1666666666665" Y="411.3333333333333" GraphRef="e3c03" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="737.1666666666665" Y="411.3333333333333" GraphRef="e3c03" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c81c0">
   <Interaction GraphId="c81c0">
     <Graphics ConnectorType="Segmented" ZOrder="12288" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="12288" LineThickness="1.0">
-
       <Point X="703.6666666666671" Y="838.6666666666671" GraphRef="bf5a0" RelX="0.5" RelY="1.0" />
+
       <Point X="703.6666666666671" Y="838.6666666666671" GraphRef="bf5a0" RelX="0.5" RelY="1.0"/>
-
       <Point X="722.0" Y="847.0" />
+
       <Point X="722.0" Y="847.0"/>
-
       <Point X="908.0000000000005" Y="850.666666666667" GraphRef="f4acf" RelX="-1.0" RelY="0.0" ArrowHead="mim-transcription-translation" />
+
       <Point X="908.0000000000005" Y="850.666666666667" GraphRef="f4acf" RelX="-1.0" RelY="0.0" ArrowHead="mim-transcription-translation"/>
-
       <Anchor Position="0.6050783383767009" Shape="None" GraphId="ac9ef" />
+
       <Anchor Position="0.6050783383767009" Shape="None" GraphId="ac9ef"/>
-
       <Anchor Position="0.12482326540671458" Shape="None" GraphId="fff87" />
+
       <Anchor Position="0.12482326540671458" Shape="None" GraphId="fff87"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c8259">
   <Interaction GraphId="c8259">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="948.6666666666666" Y="624.6666666666666" GraphRef="bab36" RelX="0.5" RelY="1.0" />
+
       <Point X="948.6666666666666" Y="624.6666666666666" GraphRef="bab36" RelX="0.5" RelY="1.0"/>
-
       <Point X="1001.3333333333334" Y="691.8333333333334" GraphRef="d5517" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="1001.3333333333334" Y="691.8333333333334" GraphRef="d5517" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.45518527261742314" Shape="None" GraphId="e8430" />
+
       <Anchor Position="0.45518527261742314" Shape="None" GraphId="e8430"/>
-
       <Anchor Position="0.7268224175665883" Shape="None" GraphId="af380" />
+
       <Anchor Position="0.7268224175665883" Shape="None" GraphId="af380"/>
-
       <Anchor Position="0.08207130825154421" Shape="None" GraphId="f730f" />
+
       <Anchor Position="0.08207130825154421" Shape="None" GraphId="f730f"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c8355">
   <Interaction GraphId="c8355">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="740.0" Y="120.0" GraphRef="cf1e9" RelX="0.0" RelY="1.0" />
+
       <Point X="740.0" Y="120.0" GraphRef="cf1e9" RelX="0.0" RelY="1.0"/>
-
       <Point X="740.0" Y="150.0" GraphRef="aa684" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="740.0" Y="150.0" GraphRef="aa684" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="c964f">
   <Interaction GraphId="c964f">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="231.08333333333331" Y="238.66666666666663" GraphRef="faf9e" RelX="-0.5" RelY="1.0" />
+
       <Point X="231.08333333333331" Y="238.66666666666663" GraphRef="faf9e" RelX="-0.5" RelY="1.0"/>
-
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ca5d2">
   <Interaction GraphId="ca5d2">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="236.0" Y="370.0" GraphRef="fd566" RelX="1.0" RelY="0.0" />
+
       <Point X="236.0" Y="370.0" GraphRef="fd566" RelX="1.0" RelY="0.0"/>
-
       <Point X="346.6666666666665" Y="345.3333333333332" GraphRef="ff2d6" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="346.6666666666665" Y="345.3333333333332" GraphRef="ff2d6" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="cb345">
   <Interaction GraphId="cb345">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="775.3333333333333" Y="474.33333333333337" GraphRef="e3f7e" RelX="-1.0" RelY="0.5" />
+
       <Point X="775.3333333333333" Y="474.33333333333337" GraphRef="e3f7e" RelX="-1.0" RelY="0.5"/>
-
       <Point X="743.6666666666667" Y="505.0" GraphRef="bc693" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="743.6666666666667" Y="505.0" GraphRef="bc693" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="cbf95">
   <Interaction GraphId="cbf95">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="203.33333333333334" Y="296.0" GraphRef="f6b05" RelX="0.0" RelY="1.0" />
+
       <Point X="203.33333333333334" Y="296.0" GraphRef="f6b05" RelX="0.0" RelY="1.0"/>
-
       <Point X="203.33333333333334" Y="322.0" GraphRef="dddb9" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="203.33333333333334" Y="322.0" GraphRef="dddb9" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="cce01">
   <Interaction GraphId="cce01">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
-
       <Point X="946.0000000000005" Y="819.3333333333337" GraphRef="f4acf" RelX="0.0" RelY="-1.0" />
+
       <Point X="946.0000000000005" Y="819.3333333333337" GraphRef="f4acf" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1001.3333333333334" Y="710.8333333333334" GraphRef="d5517" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="1001.3333333333334" Y="710.8333333333334" GraphRef="d5517" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="cce21">
   <Interaction GraphId="cce21">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="808080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="808080">
-
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" />
+
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0"/>
-
       <Point X="278.33333333333337" Y="262.0" GraphRef="e73d9" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="278.33333333333337" Y="262.0" GraphRef="e73d9" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="cd354">
   <Interaction GraphId="cd354">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
-
       <Point X="684.3333333333333" Y="343.33333333333337" GraphRef="e7262" RelX="1.0" RelY="0.5" />
+
       <Point X="684.3333333333333" Y="343.33333333333337" GraphRef="e7262" RelX="1.0" RelY="0.5"/>
-
       <Point X="737.1666666666665" Y="395.3333333333333" GraphRef="e3c03" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="737.1666666666665" Y="395.3333333333333" GraphRef="e3c03" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ce7cf">
   <Interaction GraphId="ce7cf">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="790.9999999999998" Y="403.3333333333333" GraphRef="e3c03" RelX="1.0" RelY="0.0" />
+
       <Point X="790.9999999999998" Y="403.3333333333333" GraphRef="e3c03" RelX="1.0" RelY="0.0"/>
-
       <Point X="874.8333333333333" Y="403.16666666666674" GraphRef="a9089" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="874.8333333333333" Y="403.16666666666674" GraphRef="a9089" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ceee0">
   <Interaction GraphId="ceee0">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="360.33333333333326" Y="467.1666666666667" GraphRef="e57e1" RelX="0.0" RelY="-1.0" />
+
       <Point X="360.33333333333326" Y="467.1666666666667" GraphRef="e57e1" RelX="0.0" RelY="-1.0"/>
-
       <Point X="361.0" Y="439.5" GraphRef="e771d" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="361.0" Y="439.5" GraphRef="e771d" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d0a94">
   <Interaction GraphId="d0a94">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
-
       <Point X="895.5746151429469" Y="559.5161797046811" GraphRef="f4a87" RelX="0.0" RelY="0.0" />
+
       <Point X="895.5746151429469" Y="559.5161797046811" GraphRef="f4a87" RelX="0.0" RelY="0.0"/>
-
       <Point X="921.3333333333333" Y="564.0" GraphRef="def10" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="921.3333333333333" Y="564.0" GraphRef="def10" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d0eb7">
   <Interaction GraphId="d0eb7">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="203.33333333333334" Y="338.0" GraphRef="dddb9" RelX="0.0" RelY="1.0" />
+
       <Point X="203.33333333333334" Y="338.0" GraphRef="dddb9" RelX="0.0" RelY="1.0"/>
-
       <Point X="204.5" Y="360.0" GraphRef="fd566" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="204.5" Y="360.0" GraphRef="fd566" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d0f3a">
   <Interaction GraphId="d0f3a">
     <Graphics ConnectorType="Elbow" ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ConnectorType="Elbow" ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="345.0" Y="170.0" GraphRef="e52b6" RelX="0.5" RelY="1.0" />
+
       <Point X="345.0" Y="170.0" GraphRef="e52b6" RelX="0.5" RelY="1.0"/>
-
       <Point X="398.8657512297998" Y="218.96530025057206" GraphRef="d329c" RelX="0.0" RelY="0.0" />
+
       <Point X="398.8657512297998" Y="218.96530025057206" GraphRef="d329c" RelX="0.0" RelY="0.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d104b">
   <Interaction GraphId="d104b">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="955.0" Y="377.3333333333333" GraphRef="ac8bd" RelX="-1.0" RelY="0.0" />
+
       <Point X="955.0" Y="377.3333333333333" GraphRef="ac8bd" RelX="-1.0" RelY="0.0"/>
-
       <Point X="907.1666666666667" Y="403.16666666666674" GraphRef="a9089" RelX="1.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="907.1666666666667" Y="403.16666666666674" GraphRef="a9089" RelX="1.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d1b65">
   <Interaction GraphId="d1b65">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="976.6666666666666" Y="508.0" GraphRef="ed17a" RelX="0.0" RelY="1.0" />
+
       <Point X="976.6666666666666" Y="508.0" GraphRef="ed17a" RelX="0.0" RelY="1.0"/>
-
       <Point X="972.6397576911843" Y="655.2399441441369" GraphRef="e8430" RelX="0.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="972.6397576911843" Y="655.2399441441369" GraphRef="e8430" RelX="0.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d2d7b">
   <Interaction GraphId="d2d7b">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="764.0833333333331" Y="411.3333333333333" GraphRef="e3c03" RelX="0.5" RelY="1.0" />
+
       <Point X="764.0833333333331" Y="411.3333333333333" GraphRef="e3c03" RelX="0.5" RelY="1.0"/>
-
       <Point X="775.3333333333333" Y="436.33333333333337" GraphRef="e3f7e" RelX="-1.0" RelY="-0.5" ArrowHead="Arrow" />
+
       <Point X="775.3333333333333" Y="436.33333333333337" GraphRef="e3f7e" RelX="-1.0" RelY="-0.5" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d2f11">
   <Interaction GraphId="d2f11">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="740.0" Y="197.0" GraphRef="b7b89" RelX="0.0" RelY="0.0" />
+
       <Point X="740.0" Y="197.0" GraphRef="b7b89" RelX="0.0" RelY="0.0"/>
-
       <Point X="640.0" Y="170.0" GraphRef="bb7d5" RelX="0.0" RelY="1.0" />
+
       <Point X="640.0" Y="170.0" GraphRef="bb7d5" RelX="0.0" RelY="1.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d4b9c">
   <Interaction GraphId="d4b9c">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
-
       <Point X="972.6397576911843" Y="655.2399441441369" GraphRef="e8430" RelX="0.0" RelY="0.0" />
+
       <Point X="972.6397576911843" Y="655.2399441441369" GraphRef="e8430" RelX="0.0" RelY="0.0"/>
-
       <Point X="943.3333333333335" Y="646.3333333333334" GraphRef="fc33b" RelX="1.0" RelY="0.0" />
+
       <Point X="943.3333333333335" Y="646.3333333333334" GraphRef="fc33b" RelX="1.0" RelY="0.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d4c60">
   <Interaction GraphId="d4c60">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="ff0080">
-
       <Point X="72.66666666666667" Y="427.8333333333333" GraphRef="d7ae8" RelX="0.0" RelY="-1.0" />
+
       <Point X="72.66666666666667" Y="427.8333333333333" GraphRef="d7ae8" RelX="0.0" RelY="-1.0"/>
-
       <Point X="72.33333333333334" Y="398.0" GraphRef="cc0c0" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="72.33333333333334" Y="398.0" GraphRef="cc0c0" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d4ea9">
   <Interaction GraphId="d4ea9">
     <Graphics ConnectorType="Curved" ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ConnectorType="Curved" ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="847.0" Y="546.3333333333334" GraphRef="bb691" RelX="-0.5" RelY="1.0" />
+
       <Point X="847.0" Y="546.3333333333334" GraphRef="bb691" RelX="-0.5" RelY="1.0"/>
-
       <Point X="827.0" Y="580.3333333333334" GraphRef="aaf0e" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="827.0" Y="580.3333333333334" GraphRef="aaf0e" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d4f16">
   <Interaction GraphId="d4f16">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="330.0" Y="112.0" GraphRef="bf458" RelX="0.0" RelY="1.0" />
+
       <Point X="330.0" Y="112.0" GraphRef="bf458" RelX="0.0" RelY="1.0"/>
-
       <Point X="330.0" Y="150.0" GraphRef="e52b6" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="330.0" Y="150.0" GraphRef="e52b6" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="d63c6">
   <Interaction GraphId="d63c6">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
-
       <Point X="1077.0833333333335" Y="185.33333333333334" GraphRef="d3dec" RelX="0.0" RelY="-1.0" />
+
       <Point X="1077.0833333333335" Y="185.33333333333334" GraphRef="d3dec" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1077.0833333333335" Y="130.33333333333334" GraphRef="f00ae" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="1077.0833333333335" Y="130.33333333333334" GraphRef="f00ae" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.4" Shape="None" GraphId="babf6" />
+
       <Anchor Position="0.4" Shape="None" GraphId="babf6"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="da662">
   <Interaction GraphId="da662">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="236.0" Y="370.0" GraphRef="fd566" RelX="1.0" RelY="0.0" />
+
       <Point X="236.0" Y="370.0" GraphRef="fd566" RelX="1.0" RelY="0.0"/>
-
       <Point X="451.6666666666667" Y="170.0" GraphRef="a6668" RelX="-0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="451.6666666666667" Y="170.0" GraphRef="a6668" RelX="-0.5" RelY="1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.7551734987471397" Shape="None" GraphId="d329c" />
+
       <Anchor Position="0.7551734987471397" Shape="None" GraphId="d329c"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="dc390">
   <Interaction GraphId="dc390">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="740.2143071005781" Y="285.0090283055805" GraphRef="befed" RelX="0.0" RelY="0.0" />
+
       <Point X="740.2143071005781" Y="285.0090283055805" GraphRef="befed" RelX="0.0" RelY="0.0"/>
-
       <Point X="752.3333333333333" Y="283.6666666666667" GraphRef="b3b7b" RelX="-1.0" RelY="0.0" />
+
       <Point X="752.3333333333333" Y="283.6666666666667" GraphRef="b3b7b" RelX="-1.0" RelY="0.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="df910">
   <Interaction GraphId="df910">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="640.0" Y="122.83333333333333" GraphRef="faea6" RelX="0.0" RelY="1.0" />
+
       <Point X="640.0" Y="122.83333333333333" GraphRef="faea6" RelX="0.0" RelY="1.0"/>
-
       <Point X="640.0" Y="150.0" GraphRef="bb7d5" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="640.0" Y="150.0" GraphRef="bb7d5" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="e2b87">
   <Interaction GraphId="e2b87">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="971.5833333333333" Y="132.99999999999997" GraphRef="f4c24" RelX="0.0" RelY="1.0" />
+
       <Point X="971.5833333333333" Y="132.99999999999997" GraphRef="f4c24" RelX="0.0" RelY="1.0"/>
-
       <Point X="994.0" Y="239.66666666666666" GraphRef="d08b2" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="994.0" Y="239.66666666666666" GraphRef="d08b2" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.24838709677419354" Shape="None" GraphId="ac5e5" />
+
       <Anchor Position="0.24838709677419354" Shape="None" GraphId="ac5e5"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="e384c">
   <Interaction GraphId="e384c">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="980.7360343769183" Y="148.99999999999957" GraphRef="ed286" RelX="0.0" RelY="-1.0" />
+
       <Point X="980.7360343769183" Y="148.99999999999957" GraphRef="ed286" RelX="0.0" RelY="-1.0"/>
-
       <Point X="977.1513440860215" Y="159.49462365591395" GraphRef="ac5e5" RelX="0.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="977.1513440860215" Y="159.49462365591395" GraphRef="ac5e5" RelX="0.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="e415c">
   <Interaction GraphId="e415c">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="466.6666666666667" Y="170.0" GraphRef="a6668" RelX="0.0" RelY="1.0" />
+
       <Point X="466.6666666666667" Y="170.0" GraphRef="a6668" RelX="0.0" RelY="1.0"/>
-
       <Point X="532.5" Y="323.0" GraphRef="f43ae" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="532.5" Y="323.0" GraphRef="f43ae" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="e71b9">
   <Interaction GraphId="e71b9">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="786.0000000000005" Y="844.6666666666671" GraphRef="f68be" RelX="0.0" RelY="1.0" />
+
       <Point X="786.0000000000005" Y="844.6666666666671" GraphRef="f68be" RelX="0.0" RelY="1.0"/>
-
       <Point X="826.5930215022071" Y="849.061869599506" GraphRef="ac9ef" RelX="0.0" RelY="0.0" />
+
       <Point X="826.5930215022071" Y="849.061869599506" GraphRef="ac9ef" RelX="0.0" RelY="0.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="e88f5">
   <Interaction GraphId="e88f5">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="183.74856666666665" Y="532.0" GraphRef="a99ad" RelX="-1.0" RelY="0.5" />
+
       <Point X="183.74856666666665" Y="532.0" GraphRef="a99ad" RelX="-1.0" RelY="0.5"/>
-
       <Point X="134.0" Y="554.0" GraphRef="d0a70" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="134.0" Y="554.0" GraphRef="d0a70" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="eba47">
   <Interaction GraphId="eba47">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8f8f8f">
-
       <Point X="907.8333333333334" Y="546.6666666666666" GraphRef="c03e8" RelX="-0.5" RelY="1.0" />
+
       <Point X="907.8333333333334" Y="546.6666666666666" GraphRef="c03e8" RelX="-0.5" RelY="1.0"/>
-
       <Point X="895.5746151429469" Y="559.5161797046811" GraphRef="f4a87" RelX="0.0" RelY="0.0" />
+
       <Point X="895.5746151429469" Y="559.5161797046811" GraphRef="f4a87" RelX="0.0" RelY="0.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ebfde">
   <Interaction GraphId="ebfde">
     <Comment Source="GenMAPP remarks">http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=8525</Comment>
     <Comment Source="GenMAPP remarks">http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=8525</Comment>
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="826.0" Y="283.0" GraphRef="ca546" RelX="0.0" RelY="1.0" />
+
       <Point X="826.0" Y="283.0" GraphRef="ca546" RelX="0.0" RelY="1.0"/>
-
       <Point X="793.3333333333335" Y="306.8333333333333" GraphRef="c4b6e" RelX="0.0" RelY="-1.0" ArrowHead="TBar" />
+
       <Point X="793.3333333333335" Y="306.8333333333333" GraphRef="c4b6e" RelX="0.0" RelY="-1.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ede32">
   <Interaction GraphId="ede32">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="725.3333333333333" Y="323.3333333333333" GraphRef="f5571" RelX="-1.0" RelY="0.0" />
+
       <Point X="725.3333333333333" Y="323.3333333333333" GraphRef="f5571" RelX="-1.0" RelY="0.0"/>
-
       <Point X="684.3333333333333" Y="324.33333333333337" GraphRef="e7262" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="684.3333333333333" Y="324.33333333333337" GraphRef="e7262" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f0cf4">
   <Interaction GraphId="f0cf4">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="250.0" Y="112.0" GraphRef="b14d3" RelX="0.0" RelY="1.0" />
+
       <Point X="250.0" Y="112.0" GraphRef="b14d3" RelX="0.0" RelY="1.0"/>
-
       <Point X="250.0" Y="150.0" GraphRef="b7107" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="250.0" Y="150.0" GraphRef="b7107" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f230f">
   <Interaction GraphId="f230f">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="1058.0" Y="148.99999999999997" GraphRef="e9971" RelX="0.0" RelY="-1.0" />
+
       <Point X="1058.0" Y="148.99999999999997" GraphRef="e9971" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1077.0833333333335" Y="163.33333333333334" GraphRef="babf6" RelX="0.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1077.0833333333335" Y="163.33333333333334" GraphRef="babf6" RelX="0.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f2ab1">
   <Interaction GraphId="f2ab1">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="808080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="808080">
-
       <Point X="740.0" Y="190.0" GraphRef="fdd58" RelX="0.0" RelY="0.0" />
+
       <Point X="740.0" Y="190.0" GraphRef="fdd58" RelX="0.0" RelY="0.0"/>
-
       <Point X="683.3333333333331" Y="210.5" GraphRef="ad014" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="683.3333333333331" Y="210.5" GraphRef="ad014" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f3979">
   <Interaction GraphId="f3979">
     <Graphics ZOrder="12288" LineThickness="1.0">
     <Graphics ZOrder="12288" LineThickness="1.0">
-
       <Point X="704.8792033333337" Y="861.6666666666671" GraphRef="fe4bd" RelX="0.5" RelY="-1.0" />
+
       <Point X="704.8792033333337" Y="861.6666666666671" GraphRef="fe4bd" RelX="0.5" RelY="-1.0"/>
-
       <Point X="727.5958830874089" Y="847.1103131074578" GraphRef="fff87" RelX="0.0" RelY="0.0" />
+
       <Point X="727.5958830874089" Y="847.1103131074578" GraphRef="fff87" RelX="0.0" RelY="0.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f51ee">
   <Interaction GraphId="f51ee">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="8000ff">
-
       <Point X="236.0" Y="370.0" GraphRef="fd566" RelX="1.0" RelY="0.0" />
+
       <Point X="236.0" Y="370.0" GraphRef="fd566" RelX="1.0" RelY="0.0"/>
-
       <Point X="317.6666666666667" Y="420.5" GraphRef="e771d" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="317.6666666666667" Y="420.5" GraphRef="e771d" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f6b28">
   <Interaction GraphId="f6b28">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0099">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0099">
-
       <Point X="130.33333333333326" Y="285.16666666666663" GraphRef="a1528" RelX="1.0" RelY="0.5" />
+
       <Point X="130.33333333333326" Y="285.16666666666663" GraphRef="a1528" RelX="1.0" RelY="0.5"/>
-
       <Point X="173.33333333333334" Y="286.0" GraphRef="f6b05" RelX="-1.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="173.33333333333334" Y="286.0" GraphRef="f6b05" RelX="-1.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f7931">
   <Interaction GraphId="f7931">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="801.3333333333333" Y="198.33333333333331" GraphRef="ebd8b" RelX="-1.0" RelY="0.0" />
+
       <Point X="801.3333333333333" Y="198.33333333333331" GraphRef="ebd8b" RelX="-1.0" RelY="0.0"/>
-
       <Point X="740.0" Y="190.0" GraphRef="fdd58" RelX="0.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="740.0" Y="190.0" GraphRef="fdd58" RelX="0.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="f9d6b">
   <Interaction GraphId="f9d6b">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="681.3333333333334" Y="631.3333333333334" GraphRef="b28d7" RelX="1.0" RelY="0.0" />
+
       <Point X="681.3333333333334" Y="631.3333333333334" GraphRef="b28d7" RelX="1.0" RelY="0.0"/>
-
       <Point X="952.989088901248" Y="630.1791228708953" GraphRef="f730f" RelX="0.0" RelY="0.0" />
+
       <Point X="952.989088901248" Y="630.1791228708953" GraphRef="f730f" RelX="0.0" RelY="0.0"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="faba9">
   <Interaction GraphId="faba9">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="823.6666666666666" Y="228.66666666666669" GraphRef="da00f" RelX="-0.5" RelY="-1.0" />
+
       <Point X="823.6666666666666" Y="228.66666666666669" GraphRef="da00f" RelX="-0.5" RelY="-1.0"/>
-
       <Point X="770.0" Y="220.0" GraphRef="cd799" RelX="1.0" RelY="0.0" ArrowHead="TBar" />
+
       <Point X="770.0" Y="220.0" GraphRef="cd799" RelX="1.0" RelY="0.0" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="fc40d">
   <Interaction GraphId="fc40d">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="855.6666666666666" Y="523.6666666666666" />
+
       <Point X="855.6666666666666" Y="523.6666666666666"/>
-
       <Point X="914.6666666666666" Y="576.6666666666666" GraphRef="b4f20" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="914.6666666666666" Y="576.6666666666666" GraphRef="b4f20" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.6764059063776316" Shape="None" GraphId="f4a87" />
+
       <Anchor Position="0.6764059063776316" Shape="None" GraphId="f4a87"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="fcbaf">
   <Interaction GraphId="fcbaf">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="204.5" Y="380.0" GraphRef="fd566" RelX="0.0" RelY="1.0" />
+
       <Point X="204.5" Y="380.0" GraphRef="fd566" RelX="0.0" RelY="1.0"/>
-
       <Point X="231.33333333333331" Y="424.0" GraphRef="a99ad" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="231.33333333333331" Y="424.0" GraphRef="a99ad" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="fe249">
   <Interaction GraphId="fe249">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="891.0" Y="410.0000000000001" GraphRef="a9089" RelX="0.0" RelY="1.0" />
+
       <Point X="891.0" Y="410.0000000000001" GraphRef="a9089" RelX="0.0" RelY="1.0"/>
-
       <Point X="938.6666666666666" Y="466.0" GraphRef="ed17a" RelX="-1.0" RelY="-0.5" ArrowHead="TBar" />
+
       <Point X="938.6666666666666" Y="466.0" GraphRef="ed17a" RelX="-1.0" RelY="-0.5" ArrowHead="TBar"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="ff587">
   <Interaction GraphId="ff587">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="189.64302500000002" Y="180.0" GraphRef="ed3c1" RelX="0.5" RelY="1.0" />
+
       <Point X="189.64302500000002" Y="180.0" GraphRef="ed3c1" RelX="0.5" RelY="1.0"/>
-
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="203.33333333333334" Y="276.0" GraphRef="f6b05" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <GraphicalLine GraphId="aca4c">
   <GraphicalLine GraphId="aca4c">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="8000ff">
-
       <Point X="150.99999999999991" Y="893.3333333333338" />
+
       <Point X="150.99999999999991" Y="893.3333333333338"/>
-
       <Point X="204.33333333333326" Y="893.3333333333338" ArrowHead="Arrow" />
+
       <Point X="204.33333333333326" Y="893.3333333333338" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
   </GraphicalLine>
   </GraphicalLine>
   <GraphicalLine GraphId="b1ac5">
   <GraphicalLine GraphId="b1ac5">
     <Graphics ZOrder="12288" LineThickness="3.0" Color="999999">
     <Graphics ZOrder="12288" LineThickness="3.0" Color="999999">
-
       <Point X="32.66666666666667" Y="157.66666666666666" />
+
       <Point X="32.66666666666667" Y="157.66666666666666"/>
-
       <Point X="1046.0" Y="157.66666666666666" />
+
       <Point X="1046.0" Y="157.66666666666666"/>
     </Graphics>
     </Graphics>
   </GraphicalLine>
   </GraphicalLine>
   <GraphicalLine GraphId="bafcd">
   <GraphicalLine GraphId="bafcd">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
     <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0080">
-
       <Point X="150.99999999999991" Y="912.6666666666671" />
+
       <Point X="150.99999999999991" Y="912.6666666666671"/>
-
       <Point X="204.33333333333326" Y="912.6666666666671" ArrowHead="Arrow" />
+
       <Point X="204.33333333333326" Y="912.6666666666671" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
   </GraphicalLine>
   </GraphicalLine>
   <GraphicalLine GraphId="ca36a">
   <GraphicalLine GraphId="ca36a">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="0f0f0f">
     <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0" Color="0f0f0f">
-
       <Point X="590.0" Y="70.0" />
+
       <Point X="590.0" Y="70.0"/>
-
       <Point X="590.0" Y="975.0" />
+
       <Point X="590.0" Y="975.0"/>
     </Graphics>
     </Graphics>
   </GraphicalLine>
   </GraphicalLine>
   <GraphicalLine GraphId="e0ccf">
   <GraphicalLine GraphId="e0ccf">
     <Graphics ZOrder="12288" LineThickness="3.0" Color="999999">
     <Graphics ZOrder="12288" LineThickness="3.0" Color="999999">
-
       <Point X="32.66666666666667" Y="164.33333333333334" />
+
       <Point X="32.66666666666667" Y="164.33333333333334"/>
-
       <Point X="1046.0" Y="164.33333333333334" />
+
       <Point X="1046.0" Y="164.33333333333334"/>
     </Graphics>
     </Graphics>
   </GraphicalLine>
   </GraphicalLine>
   <Label TextLabel="PKC" GraphId="a9089">
   <Label TextLabel="PKC" GraphId="a9089">
-
     <Graphics CenterX="891.0" CenterY="403.1666666666667" Width="32.333333333333336" Height="13.666666666666666" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="891.0" CenterY="403.1666666666667" Width="32.333333333333336" Height="13.666666666666666" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="SR" GraphId="a9ad9">
   <Label TextLabel="SR" GraphId="a9ad9">
-
     <Graphics CenterX="643.6666666666666" CenterY="371.0" Width="28.333333333333332" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="999999" />
+
     <Graphics CenterX="643.6666666666666" CenterY="371.0" Width="28.333333333333332" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="999999"/>
   </Label>
   </Label>
   <Label TextLabel="Phospholipase-C" GraphId="a9f40">
   <Label TextLabel="Phospholipase-C" GraphId="a9f40">
-
     <Graphics CenterX="740.3333333333334" CenterY="261.0" Width="111.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="740.3333333333334" CenterY="261.0" Width="111.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="P" GraphId="aaacd" GroupRef="bae60">
   <Label TextLabel="P" GraphId="aaacd" GroupRef="bae60">
-
     <Graphics CenterX="762.3333333333334" CenterY="565.0" Width="12.333333333333334" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="8" Valign="Middle" />
+
     <Graphics CenterX="762.3333333333334" CenterY="565.0" Width="12.333333333333334" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="8" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="PKC inhibitor 1" GraphId="ac8bd">
   <Label TextLabel="PKC inhibitor 1" GraphId="ac8bd">
     <Comment Source="GenMAPP remarks">PMID: 9861170 PMID: 1317796</Comment>
     <Comment Source="GenMAPP remarks">PMID: 9861170 PMID: 1317796</Comment>
-
     <Graphics CenterX="997.0833333333334" CenterY="377.3333333333333" Width="84.16666666666667" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="997.0833333333334" CenterY="377.3333333333333" Width="84.16666666666667" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Gbg" GraphId="ad014">
   <Label TextLabel="Gbg" GraphId="ad014">
-
     <Graphics CenterX="675.6666666666666" CenterY="220.0" Width="30.666666666666668" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="675.6666666666666" CenterY="220.0" Width="30.666666666666668" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Pip2" GraphId="b3b7b">
   <Label TextLabel="Pip2" GraphId="b3b7b">
-
     <Graphics CenterX="772.0" CenterY="283.6666666666667" Width="39.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="772.0" CenterY="283.6666666666667" Width="39.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="Gbg" GraphId="b58c7">
   <Label TextLabel="Gbg" GraphId="b58c7">
-
     <Graphics CenterX="468.5" CenterY="667.5833333333334" Width="25.0" Height="25.166666666666668" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="0033ff" />
+
     <Graphics CenterX="468.5" CenterY="667.5833333333334" Width="25.0" Height="25.166666666666668" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="0033ff"/>
   </Label>
   </Label>
   <Label TextLabel="Camk2" GraphId="bc693">
   <Label TextLabel="Camk2" GraphId="bc693">
-
     <Graphics CenterX="743.6666666666666" CenterY="513.0" Width="48.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="743.6666666666666" CenterY="513.0" Width="48.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="TR" GraphId="c04a5">
   <Label TextLabel="TR" GraphId="c04a5">
-
     <Graphics CenterX="60.0" CenterY="418.0" Width="20.333333333333332" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" Color="ff0000" />
+
     <Graphics CenterX="60.0" CenterY="418.0" Width="20.333333333333332" Height="15.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" Color="ff0000"/>
   </Label>
   </Label>
   <Label TextLabel="DAG" GraphId="c4b6e">
   <Label TextLabel="DAG" GraphId="c4b6e">
-
     <Graphics CenterX="793.3333333333334" CenterY="316.3333333333333" Width="40.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="793.3333333333334" CenterY="316.3333333333333" Width="40.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="IGFBP" GraphId="cb5f0">
   <Label TextLabel="IGFBP" GraphId="cb5f0">
-
     <Graphics CenterX="160.99999999999997" CenterY="670.6666666666666" Width="45.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="160.99999999999997" CenterY="670.6666666666666" Width="45.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Activation via CRH and cAMP" GraphId="cb9b0">
   <Label TextLabel="Activation via CRH and cAMP" GraphId="cb9b0">
-
     <Graphics CenterX="388.1666666666666" CenterY="318.99999999999994" Width="162.33333333333337" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="388.1666666666666" CenterY="318.99999999999994" Width="162.33333333333337" Height="12.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Ets complex" GraphId="cc1be">
   <Label TextLabel="Ets complex" GraphId="cc1be">
-
     <Graphics CenterX="684.6666666666671" CenterY="927.6666666666671" Width="82.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="684.6666666666671" CenterY="927.6666666666671" Width="82.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="TR " GraphId="cc3d4">
   <Label TextLabel="TR " GraphId="cc3d4">
-
     <Graphics CenterX="182.24999999999906" CenterY="872.0000000000003" Width="52.83333333333528" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="ff0000" />
+
     <Graphics CenterX="182.24999999999906" CenterY="872.0000000000003" Width="52.83333333333528" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="ff0000"/>
   </Label>
   </Label>
   <Label TextLabel="MAPK" GraphId="cd392">
   <Label TextLabel="MAPK" GraphId="cd392">
-
     <Graphics CenterX="1053.6666666666667" CenterY="505.6666666666667" Width="52.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="808080" />
+
     <Graphics CenterX="1053.6666666666667" CenterY="505.6666666666667" Width="52.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="808080"/>
   </Label>
   </Label>
   <Label TextLabel="Ca2+" GraphId="cff6d">
   <Label TextLabel="Ca2+" GraphId="cff6d">
-
     <Graphics CenterX="1043.25" CenterY="127.66666666666669" Width="30.5" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="1043.25" CenterY="127.66666666666669" Width="30.5" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="Calcium Influx" GraphId="d08b2">
   <Label TextLabel="Calcium Influx" GraphId="d08b2">
-
     <Graphics CenterX="994.0" CenterY="247.66666666666666" Width="97.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="994.0" CenterY="247.66666666666666" Width="97.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
-
   <Label TextLabel="Regulators of G-protein&#xA;signaling (RGS)" GraphId="d1733">
+
   <Label TextLabel="Regulators of G-protein&#10;signaling (RGS)" GraphId="d1733">
-
     <Graphics CenterX="1215.9999999999998" CenterY="128.5" Width="152.33333333333334" Height="22.33333333333337" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1215.9999999999998" CenterY="128.5" Width="152.33333333333334" Height="22.33333333333337" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="TR" GraphId="d3dd0">
   <Label TextLabel="TR" GraphId="d3dd0">
-
     <Graphics CenterX="857.5000000000005" CenterY="845.3333333333337" Width="31.0" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" Color="ff0000" />
+
     <Graphics CenterX="857.5000000000005" CenterY="845.3333333333337" Width="31.0" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="9" Valign="Middle" Color="ff0000"/>
   </Label>
   </Label>
-
   <Label TextLabel="Na+&#xA;" GraphId="d3dec">
+
   <Label TextLabel="Na+&#10;" GraphId="d3dec">
-
     <Graphics CenterX="1077.0833333333333" CenterY="193.33333333333334" Width="28.166666666666668" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="1077.0833333333333" CenterY="193.33333333333334" Width="28.166666666666668" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="Pathways of Myometrial Contraction" GraphId="d4fcf">
   <Label TextLabel="Pathways of Myometrial Contraction" GraphId="d4fcf">
-
     <Graphics CenterX="336.24999999999966" CenterY="912.6666666666671" Width="251.50000000000063" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" />
+
     <Graphics CenterX="336.24999999999966" CenterY="912.6666666666671" Width="251.50000000000063" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Myometrial Contraction" GraphId="d5517">
   <Label TextLabel="Myometrial Contraction" GraphId="d5517">
-
     <Graphics CenterX="1001.3333333333334" CenterY="701.3333333333334" Width="182.33333333333334" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="ff0000" />
+
     <Graphics CenterX="1001.3333333333334" CenterY="701.3333333333334" Width="182.33333333333334" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="ff0000"/>
   </Label>
   </Label>
   <Label TextLabel="Transcriptional Regulation" GraphId="d5a20">
   <Label TextLabel="Transcriptional Regulation" GraphId="d5a20">
-
     <Graphics CenterX="303.9999999999999" CenterY="872.6666666666666" Width="204.00000000000028" Height="20.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" />
+
     <Graphics CenterX="303.9999999999999" CenterY="872.6666666666666" Width="204.00000000000028" Height="20.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Transcription Factors" GraphId="d5f67">
   <Label TextLabel="Transcription Factors" GraphId="d5f67">
-
     <Graphics CenterX="80.5" CenterY="555.0" Width="109.0" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="80.5" CenterY="555.0" Width="109.0" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Pge2" GraphId="d7ae8">
   <Label TextLabel="Pge2" GraphId="d7ae8">
-
     <Graphics CenterX="72.66666666666667" CenterY="437.3333333333333" Width="44.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="72.66666666666667" CenterY="437.3333333333333" Width="44.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="RGS" GraphId="da00f">
   <Label TextLabel="RGS" GraphId="da00f">
-
     <Graphics CenterX="832.0" CenterY="236.66666666666669" Width="33.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="832.0" CenterY="236.66666666666669" Width="33.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Predicted OT-R" GraphId="db73f">
   <Label TextLabel="Predicted OT-R" GraphId="db73f">
-
     <Graphics CenterX="790.3333333333338" CenterY="945.6666666666671" Width="101.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="790.3333333333338" CenterY="945.6666666666671" Width="101.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Cell Growth" GraphId="db7e8">
   <Label TextLabel="Cell Growth" GraphId="db7e8">
-
     <Graphics CenterX="36.333333333333336" CenterY="76.33333333333333" Width="87.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="11" Valign="Middle" />
+
     <Graphics CenterX="36.333333333333336" CenterY="76.33333333333333" Width="87.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="11" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Adenylyl Cyclases" GraphId="dddb9">
   <Label TextLabel="Adenylyl Cyclases" GraphId="dddb9">
-
     <Graphics CenterX="203.33333333333334" CenterY="330.0" Width="119.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="203.33333333333334" CenterY="330.0" Width="119.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Phospholipase-C" GraphId="de99f">
   <Label TextLabel="Phospholipase-C" GraphId="de99f">
-
     <Graphics CenterX="1271.9999999999998" CenterY="584.0" Width="111.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1271.9999999999998" CenterY="584.0" Width="111.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Camk2" GraphId="e2a30">
   <Label TextLabel="Camk2" GraphId="e2a30">
-
     <Graphics CenterX="1178.333333333333" CenterY="584.6666666666665" Width="58.0" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1178.333333333333" CenterY="584.6666666666665" Width="58.0" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Calcium Mobilization" GraphId="e3c03">
   <Label TextLabel="Calcium Mobilization" GraphId="e3c03">
-
     <Graphics CenterX="737.1666666666666" CenterY="403.3333333333333" Width="107.66666666666667" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="737.1666666666666" CenterY="403.3333333333333" Width="107.66666666666667" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="NO" GraphId="e57e1">
   <Label TextLabel="NO" GraphId="e57e1">
-
     <Graphics CenterX="360.3333333333333" CenterY="476.6666666666667" Width="29.333333333333332" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="360.3333333333333" CenterY="476.6666666666667" Width="29.333333333333332" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Mg2+" GraphId="e6dd1">
   <Label TextLabel="Mg2+" GraphId="e6dd1">
-
     <Graphics CenterX="948.25" CenterY="535.6666666666666" Width="29.5" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="948.25" CenterY="535.6666666666666" Width="29.5" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="Gbg" GraphId="e73d9">
   <Label TextLabel="Gbg" GraphId="e73d9">
-
     <Graphics CenterX="295.1666666666667" CenterY="262.0" Width="33.666666666666664" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="295.1666666666667" CenterY="262.0" Width="33.666666666666664" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="Myometrial Relaxation" GraphId="e771d">
   <Label TextLabel="Myometrial Relaxation" GraphId="e771d">
-
     <Graphics CenterX="361.0" CenterY="430.0" Width="173.33333333333334" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="800080" />
+
     <Graphics CenterX="361.0" CenterY="430.0" Width="173.33333333333334" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="800080"/>
   </Label>
   </Label>
   <Label TextLabel="Pathways of Myometrial Relaxation" GraphId="e884f">
   <Label TextLabel="Pathways of Myometrial Relaxation" GraphId="e884f">
-
     <Graphics CenterX="332.91666666666634" CenterY="893.3333333333338" Width="247.50000000000063" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" />
+
     <Graphics CenterX="332.91666666666634" CenterY="893.3333333333338" Width="247.50000000000063" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Nucleus" GraphId="ec85e">
   <Label TextLabel="Nucleus" GraphId="ec85e">
-
     <Graphics CenterX="903.4166666666671" CenterY="760.3333333333337" Width="66.83333333333326" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="999999" />
+
     <Graphics CenterX="903.4166666666671" CenterY="760.3333333333337" Width="66.83333333333326" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="999999"/>
   </Label>
   </Label>
   <Label TextLabel="Pi + " GraphId="ed798">
   <Label TextLabel="Pi + " GraphId="ed798">
-
     <Graphics CenterX="919.6666666666667" CenterY="677.9999999999999" Width="62.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="11" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="919.6666666666667" CenterY="677.9999999999999" Width="62.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="11" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="Predicted Cxn43" GraphId="ee57c">
   <Label TextLabel="Predicted Cxn43" GraphId="ee57c">
-
     <Graphics CenterX="784.6666666666671" CenterY="758.6666666666671" Width="109.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="784.6666666666671" CenterY="758.6666666666671" Width="109.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="AP-1 complex" GraphId="ef32e">
   <Label TextLabel="AP-1 complex" GraphId="ef32e">
-
     <Graphics CenterX="682.6666666666671" CenterY="772.6666666666671" Width="93.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" />
+
     <Graphics CenterX="682.6666666666671" CenterY="772.6666666666671" Width="93.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle"/>
   </Label>
   </Label>
-
   <Label TextLabel="Na+&#xA;" GraphId="f00ae">
+
   <Label TextLabel="Na+&#10;" GraphId="f00ae">
-
     <Graphics CenterX="1077.0833333333333" CenterY="122.33333333333334" Width="28.166666666666668" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="1077.0833333333333" CenterY="122.33333333333334" Width="28.166666666666668" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="Ca2+" GraphId="f4c24">
   <Label TextLabel="Ca2+" GraphId="f4c24">
-
     <Graphics CenterX="971.5833333333334" CenterY="124.83333333333331" Width="31.166666666666668" Height="16.333333333333332" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="971.5833333333334" CenterY="124.83333333333331" Width="31.166666666666668" Height="16.333333333333332" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="IP3" GraphId="f5571">
   <Label TextLabel="IP3" GraphId="f5571">
-
     <Graphics CenterX="740.0" CenterY="323.3333333333333" Width="29.333333333333332" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="740.0" CenterY="323.3333333333333" Width="29.333333333333332" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="Adenylyl  Cyclases" GraphId="f6d46">
   <Label TextLabel="Adenylyl  Cyclases" GraphId="f6d46">
-
     <Graphics CenterX="282.0" CenterY="670.6666666666666" Width="123.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="282.0" CenterY="670.6666666666666" Width="123.33333333333333" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="PKC inhibitor 1" GraphId="f7310">
   <Label TextLabel="PKC inhibitor 1" GraphId="f7310">
-
     <Graphics CenterX="1223.333333333333" CenterY="461.33333333333337" Width="150.33333333333334" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1223.333333333333" CenterY="461.33333333333337" Width="150.33333333333334" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="LPA" GraphId="faea6">
   <Label TextLabel="LPA" GraphId="faea6">
-
     <Graphics CenterX="640.0" CenterY="113.33333333333333" Width="37.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080" />
+
     <Graphics CenterX="640.0" CenterY="113.33333333333333" Width="37.333333333333336" Height="19.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" Color="008080"/>
   </Label>
   </Label>
   <Label TextLabel="IGFBP" GraphId="fbff2">
   <Label TextLabel="IGFBP" GraphId="fbff2">
-
     <Graphics CenterX="35.66666666666667" CenterY="133.33333333333331" Width="45.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="35.66666666666667" CenterY="133.33333333333331" Width="45.333333333333336" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Label TextLabel="PKC" GraphId="fc28e">
   <Label TextLabel="PKC" GraphId="fc28e">
-
     <Graphics CenterX="1221.9166666666663" CenterY="321.0" Width="52.833333333333485" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1221.9166666666663" CenterY="321.0" Width="52.833333333333485" Height="16.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="10" Valign="Middle" Color="0000ff"/>
   </Label>
   </Label>
   <Shape GraphId="b3fa6">
   <Shape GraphId="b3fa6">
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
-
     <Graphics CenterX="644.0" CenterY="397.5" Width="50.0" Height="229.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" />
+
     <Graphics CenterX="644.0" CenterY="397.5" Width="50.0" Height="229.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/>
   </Shape>
   </Shape>
   <Shape GraphId="b453e">
   <Shape GraphId="b453e">
-
     <Graphics CenterX="310.58333333333326" CenterY="892.4166666666665" Width="356.8333333333335" Height="83.16666666666674" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0" />
+
     <Graphics CenterX="310.58333333333326" CenterY="892.4166666666665" Width="356.8333333333335" Height="83.16666666666674" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0"/>
   </Shape>
   </Shape>
   <Shape GraphId="ceece" GroupRef="bae60">
   <Shape GraphId="ceece" GroupRef="bae60">
-
     <Graphics CenterX="762.3962033333333" CenterY="564.5" Width="11.207593333333307" Height="11.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" Rotation="0.0" />
+
     <Graphics CenterX="762.3962033333333" CenterY="564.5" Width="11.207593333333307" Height="11.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" Rotation="0.0"/>
   </Shape>
   </Shape>
   <Shape GraphId="d4312">
   <Shape GraphId="d4312">
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
-
     <Graphics CenterX="813.0000000000005" CenterY="853.3333333333337" Width="416.0" Height="254.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" />
+
     <Graphics CenterX="813.0000000000005" CenterY="853.3333333333337" Width="416.0" Height="254.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/>
   </Shape>
   </Shape>
   <Shape GraphId="d4650">
   <Shape GraphId="d4650">
-
     <Graphics CenterX="348.34338333333335" CenterY="731.8333333333334" Width="458.6867666666667" Height="170.33333333333326" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0" />
+
     <Graphics CenterX="348.34338333333335" CenterY="731.8333333333334" Width="458.6867666666667" Height="170.33333333333326" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0"/>
   </Shape>
   </Shape>
   <Shape GraphId="eac9b">
   <Shape GraphId="eac9b">
-
     <Graphics CenterX="1219.637283333333" CenterY="406.82699999999994" Width="207.39210000000003" Height="593.6793333333333" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0" />
+
     <Graphics CenterX="1219.637283333333" CenterY="406.82699999999994" Width="207.39210000000003" Height="593.6793333333333" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0"/>
   </Shape>
   </Shape>
-
   <Group GroupId="b01f5" GraphId="a1528" Style="Group" />
+
   <Group GroupId="b01f5" GraphId="a1528" Style="Group"/>
-
   <Group GroupId="da70b" GraphId="a521c" Style="Complex" />
+
   <Group GroupId="da70b" GraphId="a521c" Style="Complex"/>
-
   <Group GroupId="b262c" GraphId="a753e" Style="Complex" />
+
   <Group GroupId="b262c" GraphId="a753e" Style="Complex"/>
-
   <Group GroupId="cb90f" GraphId="a99ad" Style="Complex" />
+
   <Group GroupId="cb90f" GraphId="a99ad" Style="Complex"/>
-
   <Group GroupId="bae60" GraphId="abe45" Style="Group" />
+
   <Group GroupId="bae60" GraphId="abe45" Style="Group"/>
-
   <Group GroupId="b38f8" GraphId="b28d7" />
+
   <Group GroupId="b38f8" GraphId="b28d7"/>
-
   <Group GroupId="ff3b9" GraphId="b3e9c" Style="Complex" />
+
   <Group GroupId="ff3b9" GraphId="b3e9c" Style="Complex"/>
-
   <Group GroupId="e8d60" GraphId="b4f20" Style="Group" />
+
   <Group GroupId="e8d60" GraphId="b4f20" Style="Group"/>
-
   <Group GroupId="a9e43" GraphId="bbf90" Style="Complex" />
+
   <Group GroupId="a9e43" GraphId="bbf90" Style="Complex"/>
-
   <Group GroupId="de038" GraphId="bf5a0" Style="Complex" />
+
   <Group GroupId="de038" GraphId="bf5a0" Style="Complex"/>
-
   <Group GroupId="ca8b3" GraphId="c8ce4" />
+
   <Group GroupId="ca8b3" GraphId="c8ce4"/>
-
   <Group GroupId="edaa9" GraphId="cc0c0" />
+
   <Group GroupId="edaa9" GraphId="cc0c0"/>
-
   <Group GroupId="f0a9f" GraphId="ccf62" />
+
   <Group GroupId="f0a9f" GraphId="ccf62"/>
-
   <Group GroupId="d37aa" GraphId="d0a70" Style="Group" />
+
   <Group GroupId="d37aa" GraphId="d0a70" Style="Group"/>
-
   <Group GroupId="f2693" GraphId="da290" Style="Complex" />
+
   <Group GroupId="f2693" GraphId="da290" Style="Complex"/>
-
   <Group GroupId="c509b" GraphId="e239d" Style="Complex" />
+
   <Group GroupId="c509b" GraphId="e239d" Style="Complex"/>
-
   <Group GroupId="ac6cc" GraphId="e3f7e" Style="Group" />
+
   <Group GroupId="ac6cc" GraphId="e3f7e" Style="Group"/>
-
   <Group GroupId="a15ef" GraphId="e7262" Style="Group" />
+
   <Group GroupId="a15ef" GraphId="e7262" Style="Group"/>
-
   <Group GroupId="dc048" GraphId="ea44e" />
+
   <Group GroupId="dc048" GraphId="ea44e"/>
-
   <Group GroupId="e2890" GraphId="ebd8b" Style="Group" />
+
   <Group GroupId="e2890" GraphId="ebd8b" Style="Group"/>
-
   <Group GroupId="af3f8" GraphId="ed17a" Style="Group" />
+
   <Group GroupId="af3f8" GraphId="ed17a" Style="Group"/>
-
   <Group GroupId="aa636" GraphId="ef2b7" />
+
   <Group GroupId="aa636" GraphId="ef2b7"/>
-
   <Group GroupId="e60e9" GraphId="f4acf" Style="Group" />
+
   <Group GroupId="e60e9" GraphId="f4acf" Style="Group"/>
-
   <Group GroupId="ab773" GraphId="f68be" Style="Complex" />
+
   <Group GroupId="ab773" GraphId="f68be" Style="Complex"/>
-
   <Group GroupId="b8909" GraphId="fa4f4" Style="Group" />
+
   <Group GroupId="b8909" GraphId="fa4f4" Style="Group"/>
-
   <Group GroupId="bcf55" GraphId="faf9e" Style="Group" />
+
   <Group GroupId="bcf55" GraphId="faf9e" Style="Group"/>
-
   <Group GroupId="e5925" GraphId="fe4bd" Style="Complex" />
+
   <Group GroupId="e5925" GraphId="fe4bd" Style="Complex"/>
-
   <InfoBox CenterX="0.0" CenterY="0.0" />
+
   <InfoBox CenterX="0.0" CenterY="0.0"/>
   <Biopax>
   <Biopax>
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">

Revision as of 21:14, 12 September 2019

Error rendering pathway page

This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.

Pathway history

View all...
CompareRevisionActionTimeUserComment
107347view19:37, 26 September 2019Khanspersfixed unconnected
106652view21:14, 12 September 2019KhanspersModified description
106149view12:04, 16 August 2019MaintBotHMDB identifier normalization
105653view05:13, 10 August 2019KhanspersModified description
102527view01:21, 4 January 2019Khanspersconverted interaction to graphical line
96894view13:53, 18 April 2018FehrhartConnected lines
89548view11:34, 16 September 2016Mkutmonremove invalid ontology tag
89543view11:30, 16 September 2016MkutmonOntology Term : 'DOID:9219' removed !
81078view04:54, 21 July 2015EgonwFixed weird characters in autors names.
80212view21:02, 22 May 2015KhanspersReverted to version '10:30, 7 January 2015' by Khanspers
80169view22:33, 14 May 2015KhanspersAdded mir219 targeting of CAMK2G
78540view10:30, 7 January 2015MaintBotadded missing graphIds
72107view22:09, 24 October 2013AlexanderPicoRemoved PRKCC; it is an alias of PRKCG
71563view19:29, 17 October 2013MaintBotremoved data source from nodes without identifier
69917view19:40, 11 July 2013MaintBotupdated to 2013 schema
45373view21:19, 7 October 2011KhanspersOntology Term : 'smooth muscle cell' added !
44933view10:58, 6 October 2011MartijnVanIerselOntology Term : 'signaling pathway' added !
44932view10:57, 6 October 2011MartijnVanIerselOntology Term : 'pregnancy complication' added !
41146view23:40, 1 March 2011MaintBotRemoved redundant pathway information and comments
38942view22:28, 24 September 2010NsalomonisSpecify description
38941view22:27, 24 September 2010NsalomonisSpecify description
38940view22:24, 24 September 2010NsalomonisModified description
38939view22:22, 24 September 2010NsalomonisModified description
38911view20:47, 24 September 2010AlexanderPico
38909view20:45, 24 September 2010AlexanderPicoSpecify description
38896view19:59, 24 September 2010AlexanderPicominor tweaks
38895view19:57, 24 September 2010AlexanderPicomajor curation: updating complexes, groups and aliases
38871view18:28, 24 September 2010KhanspersChanged line tyeps
38870view18:26, 24 September 2010Khanspers
35257view20:13, 11 February 2010Thomasmoved references from comment to bibliography
34434view18:14, 10 December 2009MaintBotAutomatic update of empty xrefs
32386view16:57, 15 August 2009MaintBotFixed text labels
32029view13:25, 14 August 2009MaintBotFixed group labels
21289view11:31, 14 November 2008MaintBot[[Pathway:Homo sapiens:Smooth muscle contraction]] moved to [[Pathway:WP289]]: Moved to stable identifier
20135view12:23, 21 October 2008Thomaslinked some unconnected lines
16754view23:28, 26 June 2008KhanspersAdded metabolits
13994view15:04, 20 May 2008Thomas
13909view19:06, 19 May 2008AlexanderPicofix attempt 3
13907view19:00, 19 May 2008AlexanderPicomoved label
13905view18:59, 19 May 2008AlexanderPicofix attempt 2
13903view18:57, 19 May 2008AlexanderPicofix attempt 1
13868view07:21, 19 May 2008AlexanderPicominor tweak
13865view07:12, 19 May 2008AlexanderPicoconnectors test2
13863view07:04, 19 May 2008AlexanderPicoReverted to version '04:17, 17 May 2008' by AlexanderPico
13861view07:02, 19 May 2008AlexanderPicoconnector test
13117view11:17, 17 May 2008MaintBotautomated metabolite conversion
12936view10:42, 17 May 2008MaintBotSticky edges patch by Sjoerd
8396view13:46, 7 January 2008MaintBot[[Pathway:Human:Smooth muscle contraction]] moved to [[Pathway:Homo sapiens:Smooth muscle contraction]]: Renaming species
7815view16:19, 18 December 2007MaintBotfixed category names
7488view12:42, 4 November 2007MaintBotAdded categories to GPML

Error details

exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/2/28/WP289_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
	at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
	at org.pathvisio.core.Engine.importPathway(Unknown Source)
	at org.pathvisio.core.util.Converter.main(Unknown Source)

<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/2/28/WP289_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 106652)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
Personal tools