Gastrin-CREB signalling pathway via PKC and MAPK (Homo sapiens)

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8, 17, 192, 34, 2312203921362418262513, 1411, 22, 29, 36, 41928, 37156, 2733, 3835XC1 ligands OxytocinOxytocin receptor 5-HT2 receptor Cholecystokinin receptors PAF receptorPAF Vasopressin receptor type 1AVP Carboxylate ligands of FFAR3 Vasopressin receptor type 1 LigandGPCR complexes that activate Gq/11 Substance P receptorSubstance P peptide P2RY2ATP Endothelin receptor G-protein alpha FPRL1FPRL1 ligands HRH1Histamine NeurotensinNeurotensin receptor GnRH receptor Catecholamine Alpha-1 adrenoceptorCatecholamine Alpha-1 adrenoceptor HRH1Histamine Bombesin-like peptide G-protein alpha GastrinCCKBR Cysteinyl leukotriene receptorsCysteinyl leukotrienes EP1 receptorPGE2 NPSNPSR P2RY10LPA GRB2SOS1 Proteinase-activated receptors LTB4 receptors Cholecystokinin receptors GnRH receptorGNRH ligands Orexin 2 receptorOrexin B FFAR2Carboxylate ligands nucleoplasmFP receptorPGF2-alpha Endothelin receptor HB-EGFp-6Y-EGFR PLC betaG alpha LPA-binding EDG receptors Basic L-amino acids Neuromedin-U receptors P2RY11 ATP CASRCalcium FPRL1 ligands CASRCalcium CHRM1, 3, 5 Group I Metabotropic glutamate receptors P2RY10LPA FFAR3Carboxylate ligands TP receptorThromboxane A2 G-protein beta-gamma complex Acyl Ghrelin TRHTRHR Bradykinin receptorBradykinin LigandGPCR complexes that activate Gq/11 Cysteinyl leukotrienes Alpha-1 adrenoceptor G-protein alpha ThrombinProteinase-activated receptors Endothelin PI3K alpha Activated thrombin Substance K receptorNeurokinin A peptide MCHMelanin-concentrating hormone receptors Melanin-concentrating hormone receptors P2RY6UDP Proteinase-activated receptors pH sensing receptors Catecholamine LTB4 receptors PAF receptorPAF Bradykinin receptorBradykinin TRH Basic L-amino acids Bombesin-like receptorbombesin-like peptide G-protein beta-gamma complex G-protein alpha Neuromedin K receptorNeurokinin B peptide GPRC6A receptorGPRC6A ligands 5-HT2 receptorSerotonin Neuromedin-UNeuromedin receptors P2RY9LPA GlucagonGCGR Carboxylate ligands of FFAR2 G-protein alpha G-protein alpha LPA-binding EDG receptors LPA G-protein alpha LTB4 receptorsLTB4 GNRH ligands P2RY1ADP GnRH receptor Melanin-concentrating hormone receptors Prokineticin receptors Heterotrimeric G-protein Gq/11 LPA-binding EDG receptors LPA Chemokine XC receptor 1 XC1 ligands EndothelinEndothelin receptor Prokineticin TP receptorThromboxane A2 EP1 receptorPGE2 Orexin 2 receptorOrexin B G-protein alpha Motilin receptorMotilin Neuropeptide FF receptorNeuropeptide FF QRFP receptorQRFP LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq XC1 ligands p21 RAS G-protein alpha Group I Metabotropic glutamate receptorsGlu Bradykinin receptor Cysteinyl leukotriene receptorsCysteinyl leukotrienes NPSNPSR pH sensing receptors MetastinKiSS1R Prokineticin G-protein beta-gamma complex Group I Metabotropic glutamate receptors pH sensing receptorsH+ Heterotrimeric G-protein Gq/11 Urotensin 2, 2B Acyl ghrelinGHSR G-protein alpha FFAR1fatty acid FFAR2Carboxylate ligands Vasopressin receptor type 1 p21 RASGTP 5-HT2 receptorSerotonin p21 RASGDP Neurotensin receptor FFAR1fatty acid MCHMelanin-concentrating hormone receptors HB-EGFp-6Y-EGFR P2RY2ATP Urotensin 2, 2B GastrinCCKBR Prokineticin receptors M1/M3/M5acetylcholine HB-EGFp-6Y-EGFR dimer Vasopressin receptor type 1AVP Cysteinyl leukotriene receptors G-protein alpha UTS2RUrotensin 2, 2B G-protein beta-gamma complex G-protein alpha Prokineticin receptorsprokineticin GRB2SOS1 Neuropeptide FF receptor FPRL1 ligands TRHTRHR Substance P receptorSubstance P peptide G-protein alpha Substance K receptorNeurokinin A peptide G-protein alpha Neuropeptide FF receptor G-protein alpha CCKCholecystokinin receptors OxytocinOxytocin receptor GlucagonGCGR Neurotensin receptor PLC-beta Bombesin-like peptide Neuromedin-SNeuromedin-U receptor 2 Prokineticin receptorsprokineticin Cysteinyl leukotriene receptors GPRC6A ligands GPR17UDP G-protein alpha Motilin receptorMotilin G-protein alpha LTB4 receptorsLTB4 GRB2SOS1HB-EGFp-6Y-EGFR G-protein alpha FP receptorPGF2-alpha GnRH receptorGNRH ligands Group I Metabotropic glutamate receptorsGlu MetastinKiSS1R Neuromedin-UNeuromedin receptors GPR17UDP Ligands of FFAR1 G-protein alpha Endothelin TRIO family RhoGEFs TRH Melanospinphoton CHRM1, 3, 5 CCKCholecystokinin receptors P2RY11 ATP FPRL1FPRL1 ligands Carboxylate ligands of FFAR2 LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq P2RY6UDP UTS2RUrotensin 2, 2B G-protein alpha Activated thrombin P2RY9LPA Heterotrimeric G-protein Gq QRFP receptorQRFP FFAR3Carboxylate ligands HB-EGFp-6Y-EGFR dimer 5-HT2 receptor pH sensing receptorsH+ ThrombinProteinase-activated receptors Protein Kinase C, alpha type DAG Neuromedin-U receptors Alpha-1 adrenoceptorCatecholamine Orexin 1 receptorOrexin A GPRC6A ligands Neuropeptide FF receptorNeuropeptide FF P2RY1ADP P2RY5LPA Neuromedin-SNeuromedin-U receptor 2 Ligands of FFAR1 Neuromedin K receptorNeurokinin B peptide G-protein alpha Carboxylate ligands of FFAR3 G-protein alpha Type 1 angiotensin II receptorAngiotensin II P2RY5LPA GPRC6A receptorGPRC6A ligands Chemokine XC receptor 1 XC1 ligands p21 RAS cytosolGastrinCCKBR NeurotensinNeurotensin receptor GNRH ligands M1/M3/M5acetylcholine G-protein alpha Melanospinphoton Cysteinyl leukotrienes LPA-binding EDG receptors Type 1 angiotensin II receptorAngiotensin II Bradykinin receptor Acyl Ghrelin G-protein alpha Orexin 1 receptorOrexin A PI3K alpha Acyl ghrelinGHSR EndothelinEndothelin receptor Bombesin-like receptorbombesin-like peptide EDN3P2RY1 O-octanoyl-L-serine-GHRL-1L-Orn OLEA GNA14 GRK5KRASGNA14 GNA14 HBEGFO-octanoyl-L-serine-GHRL-1NPSR1 GRM1 SAA1XCL2 PGF2a GDP LPAR1 AVPR1B TACR2 GNAQ PROKR2 GASTPLCB3CASR GNA11 OLEA p-ERK1/2/5GPCRs that activate Gq/11CCK CYSLTR2 OXTR MCHR2 TRHAGTPROK2 CH3COO- LTB4R2 Hist L-Lys LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq ATPp-S133-CREB15HT p-6Y-EGFR UTS2R GNA14 ADPUTS2R TBXA2RLPAR5 GCGR CCKBRFFAR3 CCL23-2 HCRTR2 HBEGFLPAR2 NMBRGZ LTC4 Ribosomal protein S6 kinaseBUT NMSO-octanoyl-L-serine-GHRL-1LTB4R HCRTGPR17 LXA4 CYSLTR1 EtCOO- or C2H5COO- L-Lys GNA11 ADRA1B LPAR6 HBEGFPGE2 GNA14 PTGER1 LPAR1 PTGER1 thrombin heavy chain GRB2-1 GNA14 DDCX GNA11 NMUR2 HXA PALM HCRTR2 HCRTR1 p21 RASGDPF2RL1ADRA1A GPR4 EDN2TBXA2RGlu GNAQ TRHG-protein beta-gamma complexGlu Ca2+ GTP NTSR2 GRM1 ATPNPSRGZ GASTGNAQ HCRTR1 NTSH+ TRHGDP ADP TRHLPAR2 Ligands of GPCRs that activate Gq/11CCKBR AVPGRM5 GNA15 CHRM1 Hist TAC3GNA11 HTR2A NMBGDP G-protein alpha MT-RNR2GNRHR2BUT PROK1 PIK3CA QRFPR NPFFR1 GNRH1LPAR3 TXA2 GNA15 TRHSAA1GDPDecS-GHRL-1AGTR1 GPR132 RGS proteins active for G alpha CCL23-2 HCRTSOS1 CYSLTR1 GNRHR GNRHR2GNA11 APPNRAS Heterotrimeric G-protein Gq/11 FPR2 GRB2SOS1PTAFR HB-EGFp-6Y-EGFR dimerMCHR1 NPFFR1 KISS1F2RL2Ca2+ P2RY10 MCHR1 FFAR1 GNA14 CHRM3 ADRA1B thrombin heavy chain HRH1 CASR HCOOH FPR2 Valerate EDN1XCL1 UTS2BUTS2BGNAQ OXTBDKRB2 thrombin light chain ATP ADRBK1P2RY1 CCKBR GNA11 GPR65 F2RL2AVPR1A L-Arg F2RL3LPAR5 NPFFH+ DecS-GHRL-1P2RY2 ATP TXA2 Pentadecanoic acid Phospho-Ribosomal protein S6 kinaseGNRHR GTP GNA14 GNA11 GPR68 GNA11 GDP CCKBR OPN4 GTP QRFPO-octanoyl-L-serine-GHRL-1GTPNAd Substance P peptide GNA15 PGE2 LTE4 CHRM5 TRHP2RY10 GNA15 TRHHTR2CEffects of PIP2 hydrolysisFFAR1 GNA15 PALM DecS-GHRL-1GCGR GPRC6A HTR2A NMSP2RY6 GHSR KISS1R PLCB4 PLC-betaHRASG-protein alpha XCL2 AGTR1 GNAQ AVPR1A HCRTHCRT5HT HCOOH LTD4 HXA XCR1 KISS1GNRH2CCKAR PRKCAFFAR2 DAGHBEGFIP2RY2 ADRA1D LPAR6 PRKCA NPFFR2 NMUR1 P2RY11 ADRBK1PMCHP2RY11 PMCHGPR17 PAF DDCX LTB4R2 NTSKRASPIF2RRAF/MAP kinase cascadeADRA1A LigandGPCR complexes that activate Gq/11Valerate GNAQ TRHQRFPAcCho FFAR3 NAd Bradykinin EDNRA ADR BDKRB2 KISS1R GRB2SOS1HB-EGFp-6Y-EGFRPIK3CA HTR2B MT-RNR2PROKR2 CYSLTR2 MLNR LTB4 GNAQ UTS2TRHR MLNR TAC3GRK5 ANXA1 SOS1 DecS-GHRL-1ADR OXTEDN1Neurokinin A peptide CH3COO- CREB1BDKRB1 GNAQ TRHGASTNMUR2 G-protein alpha XCL1 KALRN MMP3LTB4R NMUR1 L-Arg GHSR PTGFR F2RTACR1 GRM5 CCKAR NTSR2 EtCOO- or C2H5COO- L-Orn NPFFGNA11 QRFPR TRHR GRB2-1 GTP MLNGastrinCCKBRG-protein alpha GNA11 G-protein alpha ADRA1D NTSR1 OPN4 AVPNMUDAG PLCB2 GPR68 p21 RASGTPAPPProtein Kinase C, alpha type DAGGlucagon GNAQ GNA15 PROK1 EDNRB LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq PROKR1 BDKRB1 MLNNTSR1 EDN3NPSR1 EDNRA PI3K alphaPLCB1 Pentadecanoic acid TRIO LTB4 GTPGTP LPAR4 XCR1 Neurokinin A peptide PROK2 Bradykinin TRHCHRM3 UDP NRAS OXTR NMUGNAQ G-protein alpha LPAR3 LXA4 LPAR4 thrombin light chain NPSGNA15 EDNRB PAF GNA14 NPFFR2 HTR2CGNRH2PTAFR GNRH1TACR1 HRH1 UTS2LTC4 EDN2GNA14 TACR3 AcCho PLC betaG alpha G-protein alpha p-6Y-EGFR LTE4 TACR2 TRIO family RhoGEFsUDP P2RY6 MCHR2 EGFRLPA LPA PROKR1 GPR65 FFAR2 ADP F2RL1CHRM1 GNA15 CCK F2RL3ARHGEF25 GTP HBEGFADPTACR3 GNA15 PTGFR GRPHTR2B LTD4 GPRC6A GDPGASTGTP GNA15 ANXA1 AVPR1B GPR132 GPR4 Glucagon TRHCHRM5 HBEGFPGF2a GRPTRHAGTHRASGTP Substance P peptide 7, 1516, 4010, 3216, 4016, 4030, 31, 3416, 40