Gastrin-CREB signalling pathway via PKC and MAPK (Homo sapiens)

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13, 27, 402, 345, 3111, 392830, 413610718, 2033254, 143123732352415, 21, 23, 26, 331NPSNPSR Activated thrombin Vasopressin receptor type 1AVP EndothelinEndothelin receptor Motilin receptorMotilin P2RY5LPA Acyl ghrelinGHSR P2RY6UDP Bradykinin receptorBradykinin Neuropeptide FF receptor P2RY10LPA MetastinKiSS1R LigandGPCR complexes that activate Gq/11 LPA-binding EDG receptors LPA GnRH receptor OxytocinOxytocin receptor P2RY1ADP GnRH receptorGNRH ligands 5-HT2 receptorSerotonin 5-HT2 receptor GnRH receptor CHRM1, 3, 5 G-protein alpha G-protein beta-gamma complex Cholecystokinin receptors Chemokine XC receptor 1 XC1 ligands UTS2RUrotensin 2, 2B TP receptorThromboxane A2 HB-EGFp-6Y-EGFR PAF receptorPAF Neuropeptide FF receptorNeuropeptide FF EndothelinEndothelin receptor Vasopressin receptor type 1 Proteinase-activated receptors pH sensing receptorsH+ XC1 ligands MetastinKiSS1R HB-EGFp-6Y-EGFR dimer PI3K alpha Substance K receptorNeurokinin A peptide FPRL1FPRL1 ligands G-protein alpha EP1 receptorPGE2 Cysteinyl leukotriene receptors LPA-binding EDG receptors Cysteinyl leukotriene receptors HRH1Histamine G-protein beta-gamma complex TP receptorThromboxane A2 GastrinCCKBR CCKCholecystokinin receptors Bombesin-like receptorbombesin-like peptide Neuromedin-UNeuromedin receptors GastrinCCKBR Prokineticin receptors Alpha-1 adrenoceptorCatecholamine Bradykinin receptorBradykinin GPRC6A receptorGPRC6A ligands 5-HT2 receptor PI3K alpha FP receptorPGF2-alpha GPR17UDP G-protein alpha QRFP receptorQRFP NeurotensinNeurotensin receptor Neuromedin-U receptors Group I Metabotropic glutamate receptorsGlu GlucagonGCGR PAF receptorPAF MCHMelanin-concentrating hormone receptors GnRH receptorGNRH ligands Neuropeptide FF receptorNeuropeptide FF Motilin receptorMotilin Alpha-1 adrenoceptorCatecholamine Heterotrimeric G-protein Gq/11 Prokineticin FPRL1FPRL1 ligands M1/M3/M5acetylcholine Bombesin-like receptorbombesin-like peptide G-protein alpha Neurotensin receptor Endothelin GNRH ligands Heterotrimeric G-protein Gq/11 CASRCalcium Cysteinyl leukotrienes pH sensing receptors G-protein alpha G-protein alpha Substance P receptorSubstance P peptide GRB2SOS1 Neuromedin K receptorNeurokinin B peptide P2RY2ATP P2RY9LPA P2RY1ADP Group I Metabotropic glutamate receptorsGlu FFAR1fatty acid LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq Substance P receptorSubstance P peptide TRH FPRL1 ligands Ligands of FFAR1 CCKCholecystokinin receptors Chemokine XC receptor 1 XC1 ligands Proteinase-activated receptors G-protein alpha Prokineticin receptorsprokineticin Orexin 1 receptorOrexin A TRHTRHR Bombesin-like peptide NPSNPSR HB-EGFp-6Y-EGFR dimer G-protein alpha Alpha-1 adrenoceptor Cholecystokinin receptors UTS2RUrotensin 2, 2B MCHMelanin-concentrating hormone receptors LTB4 receptors Ligands of FFAR1 G-protein alpha G-protein beta-gamma complex Acyl Ghrelin LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq Carboxylate ligands of FFAR2 Neuromedin-SNeuromedin-U receptor 2 Type 1 angiotensin II receptorAngiotensin II FFAR3Carboxylate ligands pH sensing receptorsH+ P2RY6UDP cytosolGNRH ligands P2RY11 ATP FFAR3Carboxylate ligands Neuromedin-U receptors p21 RAS P2RY10LPA Carboxylate ligands of FFAR2 Melanin-concentrating hormone receptors FFAR1fatty acid Catecholamine GRB2SOS1 P2RY5LPA GPRC6A ligands G-protein alpha FFAR2Carboxylate ligands G-protein alpha PLC betaG alpha Urotensin 2, 2B p21 RAS Orexin 2 receptorOrexin B LPA-binding EDG receptors Prokineticin receptors Neuropeptide FF receptor G-protein alpha G-protein alpha NeurotensinNeurotensin receptor G-protein alpha Orexin 2 receptorOrexin B Protein Kinase C, alpha type DAG Basic L-amino acids Activated thrombin Cysteinyl leukotrienes P2RY11 ATP G-protein alpha CHRM1, 3, 5 Group I Metabotropic glutamate receptors Urotensin 2, 2B GPRC6A ligands Endothelin receptor LTB4 receptorsLTB4 G-protein alpha Prokineticin receptorsprokineticin G-protein alpha Neuromedin K receptorNeurokinin B peptide p21 RASGTP TRIO family RhoGEFs XC1 ligands Vasopressin receptor type 1 G-protein alpha LTB4 receptors Heterotrimeric G-protein Gq LTB4 receptorsLTB4 Carboxylate ligands of FFAR3 G-protein alpha GPR17UDP PLC-beta Prokineticin Cysteinyl leukotriene receptorsCysteinyl leukotrienes HRH1Histamine Basic L-amino acids EP1 receptorPGE2 LPA-binding EDG receptors LPA pH sensing receptors Bombesin-like peptide GlucagonGCGR FFAR2Carboxylate ligands G-protein alpha QRFP receptorQRFP CASRCalcium G-protein beta-gamma complex TRHTRHR GastrinCCKBR p21 RASGDP Vasopressin receptor type 1AVP Acyl Ghrelin FP receptorPGF2-alpha GRB2SOS1HB-EGFp-6Y-EGFR G-protein alpha 5-HT2 receptorSerotonin ThrombinProteinase-activated receptors Endothelin receptor Orexin 1 receptorOrexin A P2RY9LPA Melanospinphoton Group I Metabotropic glutamate receptors Carboxylate ligands of FFAR3 Neurotensin receptor LigandGPCR complexes that activate Gq/11 Acyl ghrelinGHSR Type 1 angiotensin II receptorAngiotensin II Bradykinin receptor Melanospinphoton Endothelin TRH nucleoplasmG-protein alpha Melanin-concentrating hormone receptors OxytocinOxytocin receptor P2RY2ATP Catecholamine G-protein alpha Cysteinyl leukotriene receptorsCysteinyl leukotrienes GPRC6A receptorGPRC6A ligands Substance K receptorNeurokinin A peptide Bradykinin receptor Alpha-1 adrenoceptor Neuromedin-UNeuromedin receptors HB-EGFp-6Y-EGFR ThrombinProteinase-activated receptors G-protein alpha Neuromedin-SNeuromedin-U receptor 2 FPRL1 ligands M1/M3/M5acetylcholine LXA4 GASTLPA PMCHEDNRA FFAR2 GDPGNA11 HRASG-protein alpha RGS proteins active for G alpha HBEGFPMCHPROK2 GNA11 LPAR1 MLNR QRFPGNAQ LTB4R P2RY2 NPFFR1 GTP UTS2O-octanoyl-L-serine-GHRL-1GNA14 LTD4 GTPFFAR2 ADPGNA14 L-Arg GPRC6A F2RL3NMUR1 NPSR1 BDKRB1 FFAR1 HXA Neurokinin A peptide 5HT EDN3NMBGNRH2NRAS DDCX G-protein alpha DDCX CYSLTR1 Substance P peptide TBXA2RHeterotrimeric G-protein Gq/11 GPR132 GPR17 F2REGFRLTB4R2 AcCho EtCOO- or C2H5COO- CYSLTR2 p-ERK1/2/5FFAR3 GRM5 NMUR2 TACR1 P2RY11 LPAR2 APPCCKBR HCOOH EDN3LigandGPCR complexes that activate Gq/11HRH1 LPAR4 KRASPAF IPTAFR LTB4R PTAFR PGF2a SOS1 G-protein beta-gamma complexPALM ADRBK1GRM1 GPR65 BUT F2ROXTR GDP PTGER1 NAd H+ FPR2 CYSLTR1 GNA15 ARHGEF25 TRHGNA11 GNA15 LTC4 NRAS HCRTR2 GNA11 CREB1PROK1 EtCOO- or C2H5COO- GNA14 G-protein alpha OXTR HCRTR1 DecS-GHRL-1NPSATPLPAR6 PROKR2 LTB4R2 GTP L-Orn P2RY1 GNA14 LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq ADRA1B 5HT NPFFR2 PLC-betaGNRHR AcCho GNAQ Protein Kinase C, alpha type DAGKISS1R AVPR1A FFAR3 UTS2BGNA15 MLNNTSR2 AVPR1B LTB4 LTE4 GRK5 PROKR1 LPAR1 GRPMCHR1 Bradykinin DecS-GHRL-1PRKCA GPR17 P2RY11 HRASCCKBR AVPAVPR1A CCKBR CCKBRGRK5KISS1KRASGNA15 MT-RNR2GRB2-1 XCL1 GRB2-1 NMSNTSR2 LPAR5 thrombin light chain LTC4 Ca2+ NMSRGZ LigandGPCR complexes that activate Gq/11Heterotrimeric G-protein Gq ADR HRH1 PGF2a HTR2CLTD4 GPR68 MT-RNR2GPR4 EDNRB TRHR Pentadecanoic acid Pentadecanoic acid G-protein alpha F2RL2CHRM3 PTGFR UDP GNA11 LPA L-Orn TRIO family RhoGEFsGASTthrombin light chain ATP EDN2PGE2 Substance P peptide NTSR1 DecS-GHRL-1MCHR2 P2RY6 UDP LTE4 CH3COO- ATPAVPGNAQ PIK3CA G-protein alpha GHSR PI3K alphaGNAQ GNA11 CASR GNAQ XCR1 NMUR2 AGTHTR2B TAC3AGTR1 PAF CCKAR ADRA1D PROKR2 Ca2+ G-protein alpha NPSR1 GNRH1GDP RGZ GPCRs that activate Gq/11BUT MCHR1 TBXA2REDN1GNRHR GRM5 Glucagon O-octanoyl-L-serine-GHRL-1LPAR3 GNA15 PLCB3GTPGTP MLNR Bradykinin PRKCAATP OXTOXTGNRH2GPR68 CCK GPR65 TRHLPAR5 ADP L-Lys MMP3Valerate GNA14 SOS1 GNA11 P2RY6 GastrinCCKBRHist LPAR4 HBEGFHCRTGlu F2RL1GNA15 NMUF2RL1NMULPAR2 XCL2 PALM Neurokinin A peptide HCRTR1 GDPthrombin heavy chain DAG NAd GRPGPR4 AGTR1 TRHXCR1 ADRA1A GPR132 HTR2B CHRM1 ANXA1 HTR2A CHRM3 LPAR3 p-6Y-EGFR GNA11 GNRHR2KISS1R UTS2GPRC6A TRHTACR2 PIK3CA OLEA TRHTRHNPFFR2 GNA15 SAA1HBEGFMCHR2 HTR2A F2RL2EDNRB NPFFHXA PICHRM5 GTP TRHO-octanoyl-L-serine-GHRL-1GRM1 GNA14 TRHR GNA15 HBEGFTACR1 Glu EDN2O-octanoyl-L-serine-GHRL-1QRFPR thrombin heavy chain TACR3 GNA14 L-Lys HCRTR2 HCOOH EDNRA NTSR1 Effects of PIP2 hydrolysisMLNTRHp21 RASGTPGNAQ TRHGDP GNA14 Ligands of GPCRs that activate Gq/11GNA15 Hist HCRTCASR P2RY1 GDP HBEGFGNA11 GHSR GTP KISS1HBEGFTXA2 PLCB2 TRIO UTS2BCCL23-2 NMBUTS2R CHRM5 TRHHCRTLXA4 PROK2 GASTANXA1 GTP GTP CH3COO- GNA11 TACR2 Phospho-Ribosomal protein S6 kinaseGNAQ GCGR TRHNPFFFFAR1 CHRM1 NPSADR OPN4 Ribosomal protein S6 kinaseF2RL3GTP AGTGNA14 LTB4 APPGCGR PTGFR PROK1 PLCB1 CCL23-2 XCL2 PLC betaG alpha HCRTGNRH1ADP XCL1 AVPR1B TACR3 HTR2COLEA CYSLTR2 FPR2 G-protein alpha NTSADRA1A PLCB4 GNA15 GRB2SOS1HB-EGFp-6Y-EGFRCCKAR NPFFR1 KALRN OPN4 Glucagon NMUR1 GRB2SOS1P2RY10 P2RY10 UTS2R GASTValerate LPAR6 PTGER1 ADRA1B RAF/MAP kinase cascadeL-Arg PGE2 GNA14 GNAQ HB-EGFp-6Y-EGFR dimerp-S133-CREB1NTSDAGQRFPR BDKRB2 GNRHR2CCK EDN1ADPGNAQ ADRBK1SAA1P2RY2 DecS-GHRL-1H+ TXA2 PROKR1 ADRA1D p-6Y-EGFR QRFPBDKRB2 TRHBDKRB1 p21 RASGDPGNAQ TAC39, 386, 229, 3816, 198, 17, 299, 389, 38