Cadmium and glutathione (Arabidopsis thaliana)

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CCHATX1CdGSH biosynthesis...transcript levelAPX1glutamateAsAGSH1GSH2GSHgamma-ECGSHPCMDHARglycinecysteineCd chelationCdGSHPCS1CdCdCdCdCdMDHAAPX2DHAGSSGGSHDHARNADPHNADP+H2O22 H2OGR1GR2AsA-GSH cycleMSD1FSD1CCSCSD1CSD2miR398amiR398b/cactivity levelMnSODFeSODCuZnSODSOD regulationCdGSSGGSH


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Ontology Terms



  1. Jozefczak M, Keunen E, Schat H, Bliek M, Hernández LE, Carleer R, Remans T, Bohler S, Vangronsveld J, Cuypers A; ''Differential response of Arabidopsis leavesand roots to cadmium: glutathione-related chelating capacity vs antioxidant capacity.''; Plant Physiol Biochem, 2014 PubMed Europe PMC


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107043view14:11, 17 September 2019MaintBotChEBI identifier normalization
105897view11:36, 16 August 2019MkutmonHMDB identifier normalization
82711view09:46, 23 October 2015EgonwAdded the paper from which the figure was digitized to the reference list.
82710view09:39, 23 October 2015EgonwFixed the identifier for NADP+ (the HMDB id for glutathion was used).
79443view06:51, 22 March 2015EgonwRemoved Entrez Gene xrefs where gene names where used and of which the genes are given by another gene code and identifier too.
77262view01:04, 9 August 2014AlexanderPicoone more shape sent to back
77261view01:03, 9 August 2014AlexanderPicoSet bounding shapes behind datanodes
77260view00:56, 9 August 2014AlexanderPicoModified description
77206view16:14, 5 August 2014Marijke JozefczakModified description
77205view16:11, 5 August 2014Marijke JozefczakModified description
74481view11:29, 25 April 2014Marijke Jozefczakno legend
74132view05:54, 1 April 2014EgonwRemoved a non-existing HMDB ID and cannot figure out based on the name 'DHA' what it should be.
74130view05:22, 1 April 2014EgonwReplaced an unknown HMDB identifier (not on their website) with the ChEBI one.
73612view20:35, 4 February 2014Marijke JozefczakModified title
73611view20:34, 4 February 2014Marijke JozefczakPP
72205view11:49, 27 October 2013EgonwOntology Term : 'cellular detoxification pathway' added !
71886view19:25, 21 October 2013Marijke JozefczakNew pathway

External references


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NameTypeDatabase referenceComment
2 H2OMetaboliteHMDB02111 (HMDB)
APX1GeneProductAT1G07890 (Ensembl)
APX2GeneProductAT3G09640 (Ensembl)
ATX1GeneProductAT1G66240 (Ensembl)
AsAMetaboliteHMDB00044 (HMDB)
CCHGeneProductAT3G56240 (Ensembl)
CCSGeneProductAT1G12520 (Ensembl)
CSD1GeneProductAT1G08830 (Ensembl)
CSD2GeneProductAT2G28190 (Ensembl)
CuZnSODProteinAT1G08830 (Ensembl)
DHAMetaboliteHMDB13004 (HMDB)
DHARProteinGO:0045174 (GeneOntology)
FSD1GeneProductAT4G25100 (Ensembl)
FeSODProteinAT4G25100 (Ensembl)
GR1GeneProductAT3G24170 (Ensembl)
GR2GeneProductAT3G54660 (Ensembl)
GSH1GeneProduct828409 (Entrez Gene)
GSH2GeneProductAT5G27380 (Ensembl)
GSHMetaboliteHMDB00125 (HMDB)
GSSGMetaboliteHMDB03337 (HMDB)
H2O2MetaboliteHMDB03125 (HMDB)
MDHAMetaboliteHMDB13004 (HMDB)
MDHARProteinGO:0016656 (GeneOntology)
MSD1GeneProduct820263 (Entrez Gene)
MnSODGeneProduct820263 (Entrez Gene)
NADP+MetaboliteHMDB00125 (HMDB)
NADPHMetaboliteHMDB00221 (HMDB)
PCMetaboliteGO:0046938 (GeneOntology)
PCS1GeneProductAT5G544070 (Ensembl)
cysteineMetaboliteHMDB00574 (HMDB)
gamma-ECMetaboliteHMDB01049 (HMDB)
glutamateMetaboliteHMDB00148 (HMDB)
glycineMetaboliteHMDB00123 (HMDB)
miR398aGeneProductAT2G03445 (Ensembl)
miR398b/cGeneProductAT5G14545 (Ensembl)

Annotated Interactions

No annotated interactions

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