Nanomaterial induced apoptosis (Homo sapiens)

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(Modified description)
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   <Comment Source="WikiPathways-description">Apotosis caused by nanomaterials, such as single-walled carbon nanohorns, titanium oxide, and polystyrene nanoparticles, may be induced through lysosomal impairment. For example, PAMAMs have been found to cause mitochondrial membrane destabilization, and silver and gold nanoparticles are reported to induce ER stress, which may lead to cytochrome c release from mitochondria.
   <Comment Source="WikiPathways-description">Apotosis caused by nanomaterials, such as single-walled carbon nanohorns, titanium oxide, and polystyrene nanoparticles, may be induced through lysosomal impairment. For example, PAMAMs have been found to cause mitochondrial membrane destabilization, and silver and gold nanoparticles are reported to induce ER stress, which may lead to cytochrome c release from mitochondria.
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This pathway is part the [https://assays.cancer.gov/available_assays?wp_id=WP2507 CPTAC Assay Portal].</Comment>
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Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP2507 CPTAC Assay Portal]</Comment>
   <Comment Source="WikiPathways-category">Cellular Process</Comment>
   <Comment Source="WikiPathways-category">Cellular Process</Comment>
   <BiopaxRef>ac6</BiopaxRef>
   <BiopaxRef>ac6</BiopaxRef>

Revision as of 21:19, 12 September 2019

Error rendering pathway page

This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.

Pathway history

View all...
CompareRevisionActionTimeUserComment
107131view14:21, 17 September 2019MaintBotChEBI identifier normalization
106659view21:19, 12 September 2019KhanspersModified description
105660view05:16, 10 August 2019KhanspersModified description
105112view13:33, 8 July 2019DeSlConverted UPR to Pathway node, and added WP1939 as ID.
102133view09:18, 2 December 2018EgonwReplaced Wikipedia with Wikidata identifiers.
98247view09:06, 15 August 2018Mkutmonchanged GO identifier for gene to Ensembl identifier
97098view05:35, 28 April 2018EgonwUndo revision 97097 by [[Special:Contributions/Mechebek|Mechebek]] ([[User talk:Mechebek|Talk]])
97097view20:19, 27 April 2018WpblockedModified title
92314view08:49, 20 May 2017EgonwOntology Term : 'nanomaterial response pathway' added !
89231view11:41, 24 August 2016Torresandonfix author name
88584view19:24, 11 August 2016Mkutmonfix unconnected lines
86008view08:38, 24 June 2016FehrhartAdded some missing annotatins
85993view09:45, 23 June 2016FehrhartConnected lines
78557view10:31, 7 January 2015MaintBotadded missing graphIds
74150view11:38, 1 April 2014Bart SmeetsFixed some names
74141view10:01, 1 April 2014Bart SmeetsExpanded description for nanomaterials, added some literature references
74140view09:57, 1 April 2014Bart Smeets
74139view09:07, 1 April 2014Bart SmeetsSpecify description
73824view14:59, 25 February 2014Bart Smeetsfixed some gene names to original name
73822view14:45, 25 February 2014Bart Smeetsremoved underscores UPR
73821view14:44, 25 February 2014Bart SmeetsAdded wikipedia database for UPR
73820view14:40, 25 February 2014Bart SmeetsFew GeneIDs were added
70982view20:29, 19 September 2013EgonwFound another gene ID.
70981view20:18, 19 September 2013EgonwOne more gene identifier.
70980view20:11, 19 September 2013EgonwModified description
70978view19:58, 19 September 2013EgonwAdded a number of gene identifiers.
70960view14:11, 18 September 2013Egonw
70486view11:56, 7 August 2013EgonwAdded Wikpedia's DNA entry as identifier for "DNA".
65707view12:30, 11 June 2013EgonwAdded a few caspase identifiers.
65021view20:58, 4 June 2013MaintBotModified categories
64719view08:36, 2 June 2013EgonwOntology Term : 'apoptotic cell death pathway' added !
64641view09:35, 31 May 2013AnweshaChanged the node for apoptosis (made it a pathway node)
64613view19:03, 30 May 2013EgonwAdding the last corner.
64576view05:45, 30 May 2013EgonwAdded a bit I missed yesterday.
64575view05:44, 30 May 2013EgonwAdded another section of the full pathway.
64545view16:16, 29 May 2013EgonwFixed the data source. Should be PubChem-compound.
64544view15:55, 29 May 2013EgonwAdded the ChEBI ID for the fullerenes.
64537view12:39, 29 May 2013EgonwAdded the paper from which this is a figure.
64536view12:36, 29 May 2013EgonwNew pathway

Error details

exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/0/00/WP2507_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
	at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
	at org.pathvisio.core.Engine.importPathway(Unknown Source)
	at org.pathvisio.core.util.Converter.main(Unknown Source)

<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/0/00/WP2507_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 106659)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
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