Drug Induction of Bile Acid Pathway (Homo sapiens)

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Current revision (12:10, 16 August 2019) (view source)
(HMDB identifier normalization)
 
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<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Drug Induction of Bile Acid Pathway" Version="20120826" Organism="Homo sapiens"><Comment Source="WikiPathways-description">Several drug (e.g. chlozapine) and their inhibitory effects on targets of the bile acid production pathway.</Comment>
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<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Drug Induction of Bile Acid Pathway" Version="20120826" Organism="Homo sapiens">
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  <Comment Source="WikiPathways-description">Several drug (e.g. chlozapine) and their inhibitory effects on targets of the bile acid production pathway.</Comment>
   <Comment Source="WikiPathways-category">Physiological Process</Comment>
   <Comment Source="WikiPathways-category">Physiological Process</Comment>
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     <Graphics CenterX="999.2720437878444" CenterY="332.836929225605" Width="80.0" Height="20.0" ZOrder="32773" FontSize="10" Valign="Middle" />
   </Label>
   </Label>
   <Label TextLabel="Bile Duct" GraphId="ad970">
   <Label TextLabel="Bile Duct" GraphId="ad970">
-
     <Graphics CenterX="964.2718118894417" CenterY="448.2271617738928" Width="80.0" Height="20.0" ZOrder="32774" FillColor="ffffff" FontSize="10" Valign="Middle"/>
+
     <Graphics CenterX="964.2718118894417" CenterY="448.2271617738928" Width="80.0" Height="20.0" ZOrder="32774" FillColor="ffffff" FontSize="10" Valign="Middle" />
   </Label>
   </Label>
   <Label TextLabel="Synthesis" GraphId="b3dcb">
   <Label TextLabel="Synthesis" GraphId="b3dcb">
-
     <Graphics CenterX="493.6184019887451" CenterY="153.16025865881758" Width="80.0" Height="20.0" ZOrder="32803" FillColor="ffffff" FontSize="10" Valign="Middle" ShapeType="Rectangle" LineStyle="Broken"/>
+
     <Graphics CenterX="493.6184019887451" CenterY="153.16025865881758" Width="80.0" Height="20.0" ZOrder="32803" FillColor="ffffff" FontSize="10" Valign="Middle" ShapeType="Rectangle" LineStyle="Broken" />
   </Label>
   </Label>
   <Label TextLabel="Conjugation" GraphId="b36e4">
   <Label TextLabel="Conjugation" GraphId="b36e4">
-
     <Graphics CenterX="616.1410880141533" CenterY="108.71379767878128" Width="80.0" Height="20.0" ZOrder="32804" FillColor="ffffff" FontSize="10" Valign="Middle" ShapeType="Rectangle" LineStyle="Broken"/>
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     <Graphics CenterX="616.1410880141533" CenterY="108.71379767878128" Width="80.0" Height="20.0" ZOrder="32804" FillColor="ffffff" FontSize="10" Valign="Middle" ShapeType="Rectangle" LineStyle="Broken" />
   </Label>
   </Label>
   <Label TextLabel="Secretion" GraphId="df4b5">
   <Label TextLabel="Secretion" GraphId="df4b5">
-
     <Graphics CenterX="796.7399990849337" CenterY="134.14029495645818" Width="80.0" Height="20.0" ZOrder="32805" FillColor="ffffff" FontSize="10" Valign="Middle" ShapeType="Rectangle" LineStyle="Broken"/>
+
     <Graphics CenterX="796.7399990849337" CenterY="134.14029495645818" Width="80.0" Height="20.0" ZOrder="32805" FillColor="ffffff" FontSize="10" Valign="Middle" ShapeType="Rectangle" LineStyle="Broken" />
   </Label>
   </Label>
   <Shape GraphId="c361b">
   <Shape GraphId="c361b">
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     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/>
+
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" />
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
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     <Graphics CenterX="565.4579831932775" CenterY="366.3109243697479" Width="623.0" Height="634.0" ZOrder="-2" FontSize="10" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/>
+
     <Graphics CenterX="565.4579831932775" CenterY="366.3109243697479" Width="623.0" Height="634.0" ZOrder="-2" FontSize="10" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" />
-
  </Shape>
+
-
  <Shape GraphId="efc06">
+
-
    <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Nucleus"/>
+
-
    <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
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    <Graphics CenterX="963.4390756302518" CenterY="308.37915413078804" Width="171.86134453781574" Height="347.85074523636627" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/>
+
   </Shape>
   </Shape>
   <Shape GraphId="b50d6">
   <Shape GraphId="b50d6">
-
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Nucleus"/>
+
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Nucleus" />
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
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     <Graphics CenterX="563.3004201680619" CenterY="574.3298319327747" Width="409.1134453781514" Height="174.8697478991608" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/>
+
     <Graphics CenterX="563.3004201680619" CenterY="574.3298319327747" Width="409.1134453781514" Height="174.8697478991608" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" />
   </Shape>
   </Shape>
-
   <Group GroupId="dbb0c" GraphId="c4b47" Style="Group"/>
+
   <Shape GraphId="efc06">
-
   <Group GroupId="a6e4e" GraphId="f3b0e" Style="Group"/>
+
    <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Nucleus" />
-
   <Group GroupId="acaa0" GraphId="b84be" Style="Group"/>
+
    <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
-
   <Group GroupId="e59a3" GraphId="cdb4c"/>
+
    <Graphics CenterX="963.4390756302518" CenterY="308.37915413078804" Width="171.86134453781574" Height="347.85074523636627" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" />
-
   <Group GroupId="e25fb" GraphId="e18c6" Style="Group"/>
+
  </Shape>
-
   <Group GroupId="fa088" GraphId="e5283" Style="Group"/>
+
   <Group GroupId="ff864" GraphId="ac7e0" Style="Group" />
-
   <Group GroupId="f70e3" GraphId="bc67d"/>
+
   <Group GroupId="acaa0" GraphId="b84be" Style="Group" />
-
   <Group GroupId="c0248" GraphId="cb6b7" Style="Group"/>
+
   <Group GroupId="f70e3" GraphId="bc67d" />
-
   <Group GroupId="ff864" GraphId="ac7e0" Style="Group"/>
+
   <Group GroupId="dbb0c" GraphId="c4b47" Style="Group" />
-
   <Group GroupId="f1199" GraphId="f6935"/>
+
   <Group GroupId="c0248" GraphId="cb6b7" Style="Group" />
-
   <InfoBox CenterX="0.0" CenterY="0.0"/>
+
   <Group GroupId="e59a3" GraphId="cdb4c" />
 +
   <Group GroupId="e25fb" GraphId="e18c6" Style="Group" />
 +
   <Group GroupId="fa088" GraphId="e5283" Style="Group" />
 +
  <Group GroupId="a6e4e" GraphId="f3b0e" Style="Group" />
 +
   <Group GroupId="f1199" GraphId="f6935" />
 +
   <InfoBox CenterX="0.0" CenterY="0.0" />
   <Biopax>
   <Biopax>
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
-
       <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">bile acid signaling pathway</bp:TERM>
+
       <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">drug pathway</bp:TERM>
-
       <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0001093</bp:ID>
+
       <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000754</bp:ID>
       <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
       <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
     </bp:openControlledVocabulary>
     </bp:openControlledVocabulary>
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
-
       <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">drug pathway</bp:TERM>
+
       <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">bile acid signaling pathway</bp:TERM>
-
       <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000754</bp:ID>
+
       <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0001093</bp:ID>
       <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
       <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
     </bp:openControlledVocabulary>
     </bp:openControlledVocabulary>
     <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="e7b">
     <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="e7b">
-
       <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string"/>
+
       <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string"></bp:ID>
       <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
       <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
       <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mechanistic Disease Modeling</bp:TITLE>
       <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mechanistic Disease Modeling</bp:TITLE>

Current revision

Error rendering pathway page

This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.

Pathway history

View all...
CompareRevisionActionTimeUserComment
106211view12:10, 16 August 2019MaintBotHMDB identifier normalization
97831view06:27, 10 June 2018EgonwModified description
97745view13:07, 7 June 2018RoelodModified description
97743view13:05, 7 June 2018RoelodModified description
88593view19:40, 11 August 2016Mkutmonfix unconnected lines
87242view09:57, 20 July 2016SusanOntology Term : 'bile acid signaling pathway' added !
87241view09:56, 20 July 2016SusanOntology Term : 'drug pathway' added !
78511view10:29, 7 January 2015MaintBotadded missing graphIds
70504view11:46, 8 August 2013EgonwAdded a ChEBI id for the phospholipid compound class.
68912view17:31, 8 July 2013MaintBotUpdated to 2013 gpml schema
60232view21:49, 14 March 2013EgonwAdded a reference to ChEBI for 'bile acid'.
57150view12:35, 23 January 2013EgonwUsed "PubChem-compound"
53119view01:34, 30 October 2012MaintBotModified categories
51078view14:40, 28 August 2012RiannefijtenAdded reference on which the pathway is based
51077view14:32, 28 August 2012RiannefijtenNew pathway

Error details

exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/e/ed/WP2289_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
	at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
	at org.pathvisio.core.Engine.importPathway(Unknown Source)
	at org.pathvisio.core.util.Converter.main(Unknown Source)

<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/e/ed/WP2289_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 106211)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
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