Fatty acid metabolism (Mycobacterium tuberculosis)

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Synthesis and degradation of ketone bodiesCitrate cycle (TCA cycle)Alanine and aspartate metabolismGlycerolipid metabolismFatty acid biosynthesisFatty acid elongation in mitochondriaechA9echA12echA15echA5Long-chain fatty acidechA18echA9echA13echA18fadAfadE2echA18CoAechA13CoAechA10fadD15echA17echA18.1echA1fadBtrans-Tetradec-2-enoyl-CoAfadBfadE13echA1echA13fadE2AlkanefadBcpd:C02990fadE2echA6echA14ec:1.2.1.48ko:K00255fadE4ko:K00248echA13echA15echA12cpd:C05267fadE23echA20echA2fadE23fadE13cpd:C05260echA18.1Acyl-carrier proteinltp1fadBechA18.1acetyl-CoA acetyltransferase (EC:2.3.1.9)ko:K09478echA15Hexadecanoic acidcpd:C05102echA21fadE1echA19echA18Tetradecanoyl-CoAechA4CoAechA18.1alkB(R)-3-Hydroxybutanoyl-CoAfadE13echA4echA15fadE232-trans-Dodecenoyl-CoAechA8echA16echA11CoAfadA6echA10echA7fadE1ko:K00232echA8echA18.1acetyl-CoA acetyltransferase (EC:2.3.1.9)ko:K06445echA3cpd:C05265echA7echA4fadD33echA16fadBfadE13echA12ko:K07515cpd:C05262echA6fadE2ko:K07515ec:4.2.1.74cpd:C05270echA21fadE4ko:K00255trans-Hex-2-enoyl-CoAechA10ko:K00232echA5echA8echA10echA9(S)-Hydroxyhexanoyl-CoAechA17echA12fadE23echA6echA5echA20echA17fadE1echA19echA19acetyl-CoA acetyltransferase (EC:2.3.1.9)ko:K00493trans-Hexadec-2-enoyl-CoAltp1fadE2adhBko:K06445Butanoyl-CoAechA6fadE23cpd:C05280ko:K05297echA16ec:1.18.1.4cpd:C05261aldehyde dehydrogenase (EC:1.2.1.3)echA20echA16ko:K06445echA12echA3fadE7CoAechA9echA53-Oxopalmitoyl-CoAtrans-Oct-2-enoyl-CoAechA4ltp1echA17echA13fadE4echA19echA7fadBechA16echA15fadE2ko:K00255fadBechA20ko:K06445fadA6trans-Dec-2-enoyl-CoAechA20echA21ko:K00255fadA3fadBec:4.2.1.74fadE1ec:4.2.1.74fadBechA17echA21echA3fadE13ko:K00232echA1echA11echA20echA19alkBfadE2echA12AldehydeechA9echA4ko:K08766adhE1fadA3(S)-3-Hydroxybutanoyl-CoAechA11echA2echA5echA14echA11ltp3echA18Lauroyl-CoAcpd:C00162echA8echA15Acyl-[acyl-carrier protein]fadE13fadE23echA6cpd:C00527fadA4fadE1ko:K06445echA19echA3GlutaratefadAadhechA1fadBechA11fadBfadA2cpd:C05279echA2CoAec:1.2.99.3ko:K00232echA1cpd:C00340echA15echA2fadA4echA2echA14echA4fadA5echA13echA7fadBfadBfadA5echA1echA9acetyl-CoA acetyltransferase (EC:2.3.1.9)cpd:C01944echA10ko:K00529echA2HexadecanalechA16cpd:C05274echA14ko:K00232echA8fadE4echA6Primary alcoholfadA2acetyl-CoA acetyltransferase (EC:2.3.1.9)fadBechA14ltp1ko:K00248echA7echA20echA10echA12ko:K07515echA17echA21ec:4.2.1.74ko:K06445echA10fadE1ec:4.2.1.74aldehyde dehydrogenase (EC:1.2.1.-)acetyl-CoA acetyltransferase (EC:2.3.1.9)cpd:C05263(S)-3-Hydroxybutanoyl-CoAec:6.2.1.6ko:K06445Crotonoyl-CoAko:K07515echA21ltp1(S)-Hydroxydecanoyl-CoAec:4.2.1.74fadBechA5ko:K00255echA17echA14echA21(S)-Hydroxyoctanoyl-CoAechA13echA18.1Palmitoyl-CoAec:1.1.99.20Acetoacetyl-CoA1-HexadecanolfadBechA3echA7Acetyl-CoAechA9ltp1echA2ec:1.1.1.192ko:K08765echA8echA3aldAko:K00232echA1echA19echA8echA18echA7echA16echA18.1echA11fadE1echA14cpd:C05258aldCko:K00232echA18cpd:C00435ko:K09479fadE4fadE13echA5ko:K07515echA3echA4ko:K094783-Oxohexanoyl-CoAechA11adhAfadE4echA6ko:K07515cpd:C03547fadE23ltp3fadE4ko:K00255


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CompareRevisionActionTimeUserComment
87483view01:32, 25 July 2016AlexanderPicoOntology Term : 'classic metabolic pathway' added !
87482view01:32, 25 July 2016AlexanderPicoOntology Term : 'fatty acid metabolic pathway' added !
74239view14:07, 9 April 2014EgonwRemoved a data source where no ID was given.
71860view20:38, 18 October 2013MaintBotReplaced KO with gene name
71808view16:07, 18 October 2013EgonwReplaced Kegg enzyme with Enzyme Nomenclature as database for EC numbers.
71594view19:31, 17 October 2013MaintBotAutomated update of data sources
69509view20:12, 8 July 2013MaintBotUpdated to 2013 gpml schema
46523view01:42, 12 February 2012KuocyNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
(R)-3-Hydroxybutanoyl-CoAMetaboliteC03561 (Kegg Compound)
(S)-3-Hydroxybutanoyl-CoAMetaboliteC01144 (Kegg Compound)
(S)-Hydroxydecanoyl-CoAMetaboliteC05264 (Kegg Compound)
(S)-Hydroxyhexanoyl-CoAMetaboliteC05268 (Kegg Compound)
(S)-Hydroxyoctanoyl-CoAMetaboliteC05266 (Kegg Compound)
1-HexadecanolMetaboliteC00823 (Kegg Compound)
2-trans-Dodecenoyl-CoAMetaboliteC03221 (Kegg Compound)
3-Oxohexanoyl-CoAMetaboliteC05269 (Kegg Compound)
3-Oxopalmitoyl-CoAMetaboliteC05259 (Kegg Compound)
Acetoacetyl-CoAMetaboliteC00332 (Kegg Compound)
Acetyl-CoAMetaboliteC00024 (Kegg Compound)
Acyl-[acyl-carrier protein]MetaboliteC00173 (Kegg Compound)
Acyl-carrier proteinMetaboliteC00229 (Kegg Compound)
AldehydeMetaboliteC00071 (Kegg Compound)
AlkaneMetaboliteC01371 (Kegg Compound)
Butanoyl-CoAMetaboliteC00136 (Kegg Compound)
CoAMetaboliteC00010 (Kegg Compound)
Crotonoyl-CoAMetaboliteC00877 (Kegg Compound)
GlutarateMetaboliteC00489 (Kegg Compound)
HexadecanalMetaboliteC00517 (Kegg Compound)
Hexadecanoic acidMetaboliteC00249 (Kegg Compound)
Lauroyl-CoAMetaboliteC01832 (Kegg Compound)
Long-chain fatty acidMetaboliteC00638 (Kegg Compound)
Palmitoyl-CoAMetaboliteC00154 (Kegg Compound)
Primary alcoholMetaboliteC00226 (Kegg Compound)
Tetradecanoyl-CoAMetaboliteC02593 (Kegg Compound)
acetyl-CoA acetyltransferase (EC:2.3.1.9)GeneProductRv0914c (TubercuList) Original kegg element: gene;145;mtu:Rv0243 mtu:Rv0859 mtu:Rv0914c mtu:Rv1074c mtu:Rv1135A mtu:Rv1323 mtu:Rv1867 mtu:Rv3523 mtu:Rv3546 mtu:Rv3556c
acetyl-CoA acetyltransferase (EC:2.3.1.9)GeneProductRv1135A (TubercuList) Original kegg element: gene;145;mtu:Rv0243 mtu:Rv0859 mtu:Rv0914c mtu:Rv1074c mtu:Rv1135A mtu:Rv1323 mtu:Rv1867 mtu:Rv3523 mtu:Rv3546 mtu:Rv3556c
acetyl-CoA acetyltransferase (EC:2.3.1.9)GeneProductRv1867 (TubercuList) Original kegg element: gene;145;mtu:Rv0243 mtu:Rv0859 mtu:Rv0914c mtu:Rv1074c mtu:Rv1135A mtu:Rv1323 mtu:Rv1867 mtu:Rv3523 mtu:Rv3546 mtu:Rv3556c
adhAGeneProductRv1862 (TubercuList) Original kegg element: gene;47;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
adhBGeneProductRv0761c (TubercuList) Original kegg element: gene;47;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
adhE1GeneProductRv0162c (TubercuList) Original kegg element: gene;47;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
adhGeneProductRv1530 (TubercuList) Original kegg element: gene;47;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
aldAGeneProductRv0768 (TubercuList) Original kegg element: gene;61;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldCGeneProductRv2858c (TubercuList) Original kegg element: gene;61;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldehyde dehydrogenase (EC:1.2.1.-)GeneProductRv0147 (TubercuList) Original kegg element: gene;61;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldehyde dehydrogenase (EC:1.2.1.3)GeneProductRv0458 (TubercuList) Original kegg element: gene;61;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
alkBGeneProductRv3252c (TubercuList) Original kegg element: gene;67;mtu:Rv3252c
cpd:C00162MetaboliteC00162 (Kegg Compound)
cpd:C00340MetaboliteC00340 (Kegg Compound) <