Angiogenesis overview (Homo sapiens)
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Proteosome
GF
lamellopodia and filopodia
transcription of angiogenesis-related genes
survival
eloC
MT-MMP
breakdown of extracellular
tissue like collagen
ROS
migration
survival
proliferation
migration
Integrins
TK
Stem Cell
migration
angiogenesis
permeability
Ca2+ release
Ca2+
TIMP4
MMP14
PLXND1
NRP1
SOS1
KDR
OH
AKT1
FGF1
NOX4
IP2
BMX
IQGAP1
Thrombin
Ras
PRKCA
RAF1
PTPN11
BAD
ROBO4
RAC1
NO
PLC-gamma
ANGPT1
PLCG1
PLD
ELK1
PHD
CDC42
ROBO1
SRC
CDC42
FGFR1
GRB2
DAG1
SEMA3A
DAG1
NADPH oxidase 2
VHL
PIP2
IP3
PIP2
NCK1
NOS3
PLA2G1B
CRK
VEGFA
MAP3K7
FAK
PI3K
hypoxia
MMPs
PDPK1
TIMP2
MTOR
ROBO1
urokinase-plasminogen activator
RAS
MAP2K1
SHB
MAP2K1
HIF2-alpha
Dia1
GRB2
Ras GAP
FRS2
DOK2
MAP2K4
ERK 1/2 MAPK
MAPK14
PAK1
APC
PIP3
FAK
PXN
SHC1
MAPK11
STAT3
PIK3CD
PRKCA
Ras
MAPK8
SLIT2
PTPN11
MAPK1
AKT1
RAF1
TEK
MMP2
MMP12
ATF2
SEMA4A
ROBO4
CRK
STAT5
WASP
GRB14
MMP9
MAP2K6
HIF2-alpha
HIF2-alpha
OH
pUb
eloB
GRB2
SOS1
GRB7
SLIT2
Stem Cell
Stem Cell
lamellopodia and filopodia
SLIT2
Description
Overview of processes involved in the development of angiogenesis in humans.
Comments
GF
Quality Tags
Ontology Terms
Saving...
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
106214
view
12:11, 16 August 2019
MaintBot
HMDB identifier normalization
85555
view
08:32, 29 May 2016
Egonw
Replaced a mim-conversion with Arrow.
71385
view
18:41, 17 October 2013
MaintBot
Automated update of data sources
71268
view
21:58, 16 October 2013
MaintBot
Automated update of data sources
69001
view
17:45, 8 July 2013
MaintBot
Updated to 2013 gpml schema
59192
view
19:07, 22 February 2013
MaintBot
Updated Ensembl and UniProt data source
58505
view
19:00, 14 February 2013
MaintBot
Modified title
44954
view
12:37, 6 October 2011
MartijnVanIersel
Ontology Term : 'growth factor signaling pathway' added !
44820
view
13:30, 5 October 2011
Susan
Modified description
44464
view
18:42, 14 September 2011
MaintBot
Modified categories
44462
view
14:33, 14 September 2011
Helix
angiogenesis overview
44393
view
10:35, 8 September 2011
Helix
angiogenesis overviuew
44392
view
10:26, 8 September 2011
Helix
Periodical save, work in progress
44389
view
10:15, 8 September 2011
Helix
Periodical save, work in progress
43912
view
12:37, 16 August 2011
Helix
angiogensisi overview
43911
view
12:29, 16 August 2011
Helix
Periodical save, work in progress
43909
view
12:19, 16 August 2011
Helix
Periodical save, work in progress
43908
view
11:54, 16 August 2011
Helix
Periodical save, work in progress
43907
view
11:43, 16 August 2011
Helix
Periodical save, work in progress
43906
view
11:31, 16 August 2011
Helix
angiogenesis overview
43905
view
11:11, 16 August 2011
Helix
Periodical save, work in progress
43902
view
11:48, 15 August 2011
Helix
angiogenesis overview
43901
view
11:46, 15 August 2011
Helix
Periodical save, work in progress
43900
view
11:36, 15 August 2011
Helix
Periodical save, work in progress
43899
view
11:26, 15 August 2011
Helix
Periodical save, work in progress
43898
view
11:15, 15 August 2011
Helix
Periodical save, work in progress
43896
view
11:04, 15 August 2011
Helix
angiogenesis overview
43605
view
09:00, 7 July 2011
Helix
angiopgenesis overview
43604
view
08:57, 7 July 2011
Helix
Periodical save, work in progress
43603
view
08:46, 7 July 2011
Helix
Periodical save, work in progress
43602
view
08:36, 7 July 2011
Helix
Periodical save, work in progress
43596
view
09:28, 6 July 2011
Helix
angiogenesis overview
43146
view
13:05, 3 June 2011
Helix
angiogenesis overview
43145
view
12:58, 3 June 2011
Helix
Periodical save, work in progress
43144
view
12:48, 3 June 2011
Helix
Periodical save, work in progress
43143
view
12:37, 3 June 2011
Helix
Periodical save, work in progress
43142
view
12:27, 3 June 2011
Helix
Periodical save, work in progress
43141
view
12:17, 3 June 2011
Helix
Periodical save, work in progress
43140
view
11:38, 3 June 2011
Helix
Periodical save, work in progress
43139
view
11:28, 3 June 2011
Helix
Periodical save, work in progress
43138
view
11:17, 3 June 2011
Helix
Periodical save, work in progress
43137
view
11:07, 3 June 2011
Helix
Periodical save, work in progress
43136
view
10:43, 3 June 2011
Helix
Periodical save, work in progress
43135
view
10:40, 3 June 2011
Helix
angiogenesis overview
43134
view
10:33, 3 June 2011
Helix
Periodical save, work in progress
43133
view
10:23, 3 June 2011
Helix
Periodical save, work in progress
43132
view
10:13, 3 June 2011
Helix
Periodical save, work in progress
43106
view
11:40, 2 June 2011
Helix
angiogenesis overview
43105
view
11:33, 2 June 2011
Helix
Periodical save, work in progress
43104
view
11:23, 2 June 2011
Helix
Periodical save, work in progress
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AKT1
GeneProduct
ENSG00000142208 (Ensembl)
ANGPT1
GeneProduct
ENSG00000154188 (Ensembl)
APC
GeneProduct
ENSG00000134982 (Ensembl)
ATF2
GeneProduct
ENSG00000115966 (Ensembl)
BAD
GeneProduct
ENSG00000002330 (Ensembl)
BMX
GeneProduct
ENSG00000102010 (Ensembl)
CDC42
GeneProduct
ENSG00000070831 (Ensembl)
CRK
GeneProduct
ENSG00000167193 (Ensembl)
DAG1
GeneProduct
ENSG00000173402 (Ensembl)
DOK2
GeneProduct
ENSG00000147443 (Ensembl)
Dia1
Protein
NP_031884.1 (RefSeq)
ELK1
GeneProduct
ENSG00000126767 (Ensembl)
ERK 1/2 MAPK
Protein
FAK
Protein
FAK
Protein
Q14289 (Uniprot-TrEMBL)
FGF1
GeneProduct
ENSG00000113578 (Ensembl)
FGFR1
GeneProduct
ENSG00000077782 (Ensembl)
FRS2
GeneProduct
ENSG00000166225 (Ensembl)
GRB14
GeneProduct
ENSG00000115290 (Ensembl)
GRB2
GeneProduct
ENSG00000177885 (Ensembl)
GRB7
GeneProduct
ENSG00000141738 (Ensembl)
HIF2-alpha
Protein
IP2
Protein
IP3
IQGAP1
GeneProduct
ENSG00000140575 (Ensembl)
KDR
GeneProduct
ENSG00000128052 (Ensembl)
MAP2K1
GeneProduct
ENSG00000169032 (Ensembl)
MAP2K4
GeneProduct
ENSG00000065559 (Ensembl)
MAP2K6
GeneProduct
ENSG00000108984 (Ensembl)
MAP3K7
GeneProduct
ENSG00000135341 (Ensembl)
MAPK11
GeneProduct
ENSG00000185386 (Ensembl)
MAPK14
GeneProduct
ENSG00000112062 (Ensembl)
p38 MAPK
MAPK1
GeneProduct
ENSG00000100030 (Ensembl)
MAPK8
GeneProduct
ENSG00000107643 (Ensembl)
MMP12
Protein
MMP14
GeneProduct
ENSG00000157227 (Ensembl)
MMP2
GeneProduct
ENSG00000087245 (Ensembl)
MMP9
GeneProduct
ENSG00000100985 (Ensembl)
MMPs
GeneProduct
ENSG00000087245 (Ensembl)
MTOR
GeneProduct
ENSG00000198793 (Ensembl)
NADPH oxidase 2
Protein
NCK1
GeneProduct
ENSG00000158092 (Ensembl)
NO
NOS3
GeneProduct
ENSG00000164867 (Ensembl)
NOX4
GeneProduct
ENSG00000086991 (Ensembl)
NRP1
GeneProduct
ENSG00000099250 (Ensembl)
OH
PAK1
GeneProduct
5058 (Entrez Gene)
PDPK1
GeneProduct
ENSG00000140992 (Ensembl)
PHD
Protein
PI3K
Protein
PIK3CD
GeneProduct
ENSG00000171608 (Ensembl)
PIP2
Protein
PIP2
Metabolite
HMDB0010032 (HMDB)
PIP3
Protein
PLA2G1B
GeneProduct
ENSG00000170890 (Ensembl)
PLC-gamma
GeneProduct
ENSG00000124181 (Ensembl)
PLCG1
GeneProduct
ENSG00000124181 (Ensembl)
PLD
Protein
PLXND1
GeneProduct
ENSG00000004399 (Ensembl)
PRKCA
GeneProduct
ENSG00000154229 (Ensembl)
PTPN11
GeneProduct
ENSG00000179295 (Ensembl)
PXN
GeneProduct
ENSG00000089159 (Ensembl)
RAC1
GeneProduct
ENSG00000136238 (Ensembl)
RAF1
GeneProduct
ENSG00000132155 (Ensembl)
RAS
GeneProduct
ENSG00000133703 (Ensembl)
ROBO1
GeneProduct
ENSG00000169855 (Ensembl)
ROBO4
GeneProduct
ENSG00000154133 (Ensembl)
Ras
Protein
Ras
Protein
ENSG00000133703 (Ensembl)
Ras GAP
Protein
SEMA3A
GeneProduct
ENSG00000075213 (Ensembl)
SEMA4A
GeneProduct
ENSG00000196189 (Ensembl)
SHB
GeneProduct
ENSG00000107338 (Ensembl)
SHC1
GeneProduct
ENSG00000160691 (Ensembl)
SLIT2
GeneProduct
ENSG00000145147 (Ensembl)
SOS1
GeneProduct
ENSG00000115904 (Ensembl)
SRC
GeneProduct
ENSG00000197122 (Ensembl)
STAT3
Protein
STAT5
Protein
TEK
GeneProduct
ENSG00000120156 (Ensembl)
TIMP2
GeneProduct
ENSG00000035862 (Ensembl)
TIMP4
GeneProduct
ENSG00000157150 (Ensembl)
Thrombin
Protein
176930 (OMIM)
VEGFA
GeneProduct
ENSG00000112715 (Ensembl)
VHL
GeneProduct
ENSG00000134086 (Ensembl)
WASP
Protein
P42768 (Uniprot-TrEMBL)
hypoxia
pUb
urokinase-plasminogen activator
Protein
Annotated Interactions
No annotated interactions
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