Integrated Breast Cancer Pathway (Homo sapiens)

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961141828141953715101661220G2BASC ComplexSG1MCell Cycle1, 17, 20Lithium ChlorideFulvestrantPPRB/RBAnastrozoleCCND1DonepezilLetrozoleCDK4UBIMBMPR2CDH1CHK2HydroxyureaSIRT1PTENANXA1HDAC1PMLPIAS1fra-1JKIP1CTNB1RAD50NCOA2Anti-ApoptosisBLMDHTWEE1FlutamideCell proliferationAHRRAC1RASGRP3CorticosteroneE2F1TamoxifenTCF/LEFBRAFGADD45AAngiogenesisNF1SP1ABC3GE2F1SMAD7GRMDM2Q8NBS1SMAD3CASP3HDAC1/HDAC2CASP3CDC25ABRCA2Gene ExpressionBACH1Proliferative genesMTORP53SMEK1RALASMAD6CREBCell SurvivalPLK3CANOXA1ERKBleomycinMPIP2TranscriptionLapatnibFADDFOXO1P53P85AHIPK2CIP1RHOCDK2PRHDAC1FLIP1DNASELKFluoxymesteroneRAFC9JNK1Cell Cycle arrestATMSTAT1SMAD4AmpicillinP38RAD51TestosteroneJUNMRE11DihydrotestosteronePAK1GSK3AUBP16WEE1MMP1BARD1PHBCancer DevelopmentITPKCIKKARAD54LTAK1LODC1NAB1RRASUBP15TAB1Conjugated Estrogenscyc-DC9JNK1STK11MAXGRNTetradecanoylphorbol AcetateESR1CASP9RHEBNocodazoleSMAD2CycloheximideATF1BRCA1UBE2FATMDCAKDAQP73XRCC3ATRCERKSMAD4CDK2EGFRATRPLK1RRASERPPARP65RALGAPA1UBP21B5MEC1ALKB1BADPKCB1MSH6ProteinC9JNK1CSNK1DTGFR1DAG1CYP19A1RASGEF1APenicillin GTFPIBIDFADDP13P85MYT1UBP21SMCA4BCL2ABL1ApoptosisCBPCERK1TGFR2SMEK2TSC1IMPA1P13KMethyl MethanesulfonateCASP8TRADDIPKAJAK1MDM2BRCA1HydrocortisonePLK3MPIP1ZMIZ1MYCNFKB1CDK7RRASBADRPP38TSC2IKKAARBMPR1ABARD1ProteasomeBAXAURKAGCRSMAD7SMEK1MitomycinPaclitaxelAKT1CDC42CHK1MYCJUNMAPKsCTNB1 degradationKRASBAKDexamethasoneANDREstradiolApoptosisPlicamycinCERK1TSC1ERAL1IRS1GDIVEGFAExemstaneMSH2RHONCOA3ATRRaloxifeneB3KP27AKT1EP300SMAD1RAP1ACell survival and Proliferation13