Semaphorin interactions (Homo sapiens)

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7, 11, 36, 37, 4035, 42281, 34, 5217, 30135, 18, 33, 533239, 518, 22, 445815, 25, 31, 50, 554, 20, 2327, 29, 52385816, 391433, 4613, 26, 51, 566, 24, 5221, 419, 4520, 2313, 51, 5610, 1943, 48493, 12, 47, 54, 572cytosolcytosolcytosolcytosolcytosolCD72SEMA4D RAC1 SEMA5A ROCK1,ROCK2ARHGAP35 RND1 MYH9 ATPATPSEMA6A p-Y-PLXNA3 PLXNA4 ADPFES RHOA ROCK2 FES p-Y-DPYSL3 FYN p-Y-PLXNB1 SEMA3A FYN RND1 PAK1 PLXNA2 R-Ras-GTPMYH14 GTP p-T509,T514,S518,S522-DPYSL3 FES p-Y-PLXNA1 p-Y-PLXNA2 GTP ARHGEF11 CDC42 PLXNA4 p-Y-PLXNB1 NRP1 ATPSema4D:pPlexin-B1:Metp-S522-DPYSL3 ARHGEF12 HSP90AB1 ADPNRP1 RRAS GSK3BTLN1 DPYSL5 ITGA1 NRP1:PlexinA1-4:FARP2:FYNSEMA4A MYH9 RAC2 TYROBP CDK5R1(1-307) GDP FYN SEMA3A Sema3A:NRP-1:pPlexin-A:Fyn:FesMg2+ R-Ras-GDPITGA1 p-S544-DPYSL4 RAC1 Cdk5:p35GDP FYN PAK1 ERBB2 p-Y-PLXNA2 p-Y-PLXNA4 PIP5K1gamma:Talin-1SEMA6A:PLXNA2,PLXNA4R-Ras-GTPFES FESPLXND1Sema3A dimerSEMA3A LIMK2 p-Y-PLXNA4 FARP2:PIP5KIgammaRHOA PAK2 HSP90AA1 p-Y-PLXNB1 Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAKSmoothmuscle/non-musclemyosin IIRAC1 Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP'sSEMA3A RAC1 p-T509,T514,S518,S522-CRMP1 RHOG PiCDK5R1(1-307) FYN FES PAK1,2,3 dimerPLXNA1 GTP PLXNA4 RAC2 ATPGTP PAK1 MYH11 SEMA4APlexin-B1:MetSema3A:Nrp-1:PlexinA:FynCFL1MET PLXNA2 CDK5R1(1-307) ARHGEF11 LARG and PDZ-RhoGEFPLXNA4 PLXNB1 PLXNA3 GTP ADPSema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP:Rnd1PLXNA1 MYL12B PAK3 GDPNRP1 Pip-S522-DPYSL2 PiMET p-S141,T402-PAK2 Plexin-A1-4:FYNADPSEMA7A PLXNA4 Plexin-B1:ErbB2PLXNA1 ROCK2 p-Y-PLXNA1 RND1 ADPADPGDP RHOA PLXNB3ARHGEF12 RhoA (Mgcofactor):GTPSEMA4D:pPlexin-B1:ErbB2 complexTYROBP p-Y-PLXNA2 SEMA6DSEMA4D RAC1 PAK3 SEMA3A p-T19,S20-MYL12B Rnd1-GTPNRP1 SEMA7A HSP90AA1 RHOC SEMA3A:PLXND1p-Y-PLXNA4 FYN PLXND1PLXNA2 RHOA/B/C:GTPSema3A:Nrp-1:PlexinA:Rac1-GTP:PAKRND1 TREM2 RAC1 SEMA6Ap-T509,T514,S518,S522-DPYSL2 SEMA4D p-Y-PLXNA1 NRP1 PLXNA3 PIP5K1C FYN MYH10 p-Y-PLXNB1 HSP90AA1,HSP90AB1ERBB2 ROCK1 MYL9 PLXNA4 FARP2 PTPRCFES NRP1MET Sema3A:Nrp-1:PlexinA:FynPLXNA2 RAC1 ADPATPPLXNA2,PLXNA4p-Y-PLXNB1 PAK2 RHOG RHOB GTP SEMA4D RHOB GTP PAK2 PLXNC1 PLXNA3 p-S,T508-LIMK1 PLXNA1 p-T508-LIMK1 SEMA7Ap-Y-PLXNA3 ADPp-T19,S20-MRLC-smooth muscle/non-muscle myosin IIp-Y15-CDK5 MET ATPIntegrin alpha1beta1SEMA4D dimerSEMA4A:PLXND1PIP5K1C GDP p-Y-CRMP1 RhoA,B,C:GDPSEMA4Dp-Y-PLXNA1 PLXNA4 Sema4D:pPlexin-B1:Met:RAC1-GTPCRMP's tetramersFYN GTP SEMA3A PLXNA2 Sema3A:Nrp-1:PlexinA:Fyn:pCdk5p-Y-PLXNA1 SEMA7A:PLXNC1SEMA6D:PLXNA1:TREM2:DAP12GTP DPYSL2 PLXNA4 NRP1 p-Y-PLXNA2 SEMA7A:Integrinalpha1beta1RAC1 GTP p-Y-PLXNA3 PLXNA2 ATPPLXNA4 Rnd1-GTPPLXNA2 Sema3A:NP-1:Plexin-A:Fes:CRMPp-Y-PLXNA3 ADPRRAS MYL6 SEMA4D RAC1 RHOA p-T505-LIMK2 MYH11 p-T508-LIMK1 PLXNA3 CDK5R1(1-307) SEMA4D:CD72PLXNA2 FARP2p-Y-PLXNA3 ARHGAP35ERBB2 FYN SEMA3A SEMA3A Sema4D:Plexin-B1:Rac-Rnd1:LARG/PDZ-RhoGEFSema4D:pPlexin-B1:ErbB2:Rac1:Rnd1p-Y-PLXNA3 PLXND1 SEMA4D PTPRC SEMA3EADPp-Y-DPYSL4 p-Y15-CDK5 RHOC CD72 PLXNB3 RRAS p-S534-DPYSL5 LIMK1SEMA5A:PLXNB3NRP1 GTP RHOA PLXNA3 SEMA3A p-S,T508-LIMK1 DPYSL4 PLXNA3 RHOC MET RHOA GTPNRP1 ATPRND1 PLXNC1RND1 PLXNA2 NRP1 Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTPPLXND1 p-Y-PLXNA4 p-S522-CRMP1 FYN p-Y-PLXNB1 GTP PAK1,2,3PLXNA1 p-LIMKSEMA4D ROCK1 DPYSL3 PLXNA1 GTPp-S534-DPYSL5 PLXNA1 CRMP1 p-S3-CFL1 pLIMK dimer:HSP-90p-Y-PLXNA4 ADPp-Y-PLXNA2 MYL6 p-Y-PLXNA2 NRP1 Mg2+ p-Y-PLXNA1 GTP PLXNA1 NRP1:PlexinA1-4:FYNGTP ATPFYN SEMA5AADPSEMA4D SEMA4D Sema3A dimerFYN ERBB2 LIMK1 TREM2 PLXNA3 GTP SEMA3A p-T508-LIMK1PLXNA1 RAC1:GDPITGB1 SEMA3A pCofilin: ActiveLIMK-1RhoA (Mgcofactor):GDPRAC1:GTPADPPLXNA2 GTP p-Y-PLXNB1 ATPGTP R-Ras-GDPp-S154,T436-PAK3 p-T19,S20-MYL9 ATPSEMA3A PLXNA3 RRAS ITGB1 NRP1 HSP90AB1 RND1 ActivatedROCK:RhoA/B/C:GTPSEMA3A Sema4D:pPlexin-B1:Met:Rnd1CDC42 FARP2 RHOA GTP NRP1 ATPp-Y-DPYSL2 FYN Sema4D:Plexin-B1:p190RhoGAP:Rac:Rnd1Active LIMK1PLXNA4 SEMA4D:PTPRCATPp-S544-DPYSL4 PLXNA1 CDK5 SEMA4D MYH14 PLXNB1 p-Y-DPYSL5 SEMA6D p-Y15-CDK5 SEMA4D PAK3 p-Y-PLXNA4 GDP SEMA3E TLN1RHOB RAC1:GTPRAC1 LIM KinasesSema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP'sGDPPLXNA1:TREM2:DAP12SEMA4D dimerFYN MYH10 NRP1 p-S144,T423-PAK1