Semaphorin interactions (Homo sapiens)

From WikiPathways

Revision as of 11:54, 16 July 2014 by ReactomeTeam (Talk | contribs)
Jump to: navigation, search
8, 12, 19, 37, 411, 3262, 441, 23, 32404631, 3910, 16, 4227174314, 21, 24, 365, 4415, 26472522, 333, 16, 45174, 382920, 485, 13, 469, 307, 11, 1618, 355, 13, 28, 4634, 36RAC1-GTP [cytosol]p-2Y-PAK [cytosol]NRP1:p-Plexin-A1-4:FYN[plasma membrane]Sema4D:pPlexin-B1:Met[plasma membrane]Sema3A dimer[extracellularregion]Sema3A dimer[extracellularregion]Sema3A dimer[extracellularregion]Rnd1-GTP [cytosol]RAC1-GTP [cytosol]Rnd1-GTP [cytosol]Phosphorylatedsmoothmuscle/non-musclemyosin 2 regulatorylight chains[cytosol]Sema3A dimer[extracellularregion]SEMA4D dimer [plasmamembrane]SEMA5A:PLXNB3[plasma membrane]Rnd1-GTP [cytosol]p-Plexin-A1-4[plasma membrane]Sema3A:NRP-1:pPlexin-A:fyn[plasma membrane]SEMA6A:PLXNA2,PLXNA4[plasma membrane]NRP1:p-Plexin-A1-4:FYN[plasma membrane]Plexin-A1-4 [plasmamembrane]R-Ras-GTP [plasmamembrane]Sema3A dimer[extracellularregion]Sema3A:NRP-1:pPlexin-A:Fyn:Fes[plasma membrane]Sema4D:Plexin-B1:Rac-Rnd1:LARG/PDZ-RhoGEF[plasma membrane]Plexin-B1:Met[plasma membrane]RhoA/B/C [plasmamembrane]R-Ras-GTP [plasmamembrane]RAC1-GDP [cytosol]Sema3A:NRP-1:pPlexin-A:fyn[plasma membrane]Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK[plasma membrane]RhoA/B/C [plasmamembrane]DAP12 dimer [plasmamembrane]pPlexin-B1:ErbB2[plasma membrane]Rnd1-GTP [cytosol]PlexinA1-4:FYN:pCdk5:p53[plasma membrane]Sema4D:pPlexin-B1:Met[plasma membrane]NRP1:PlexinA1-4:FARP2:FYN[plasma membrane]Sema3A:NRP-1:pPlexin-A:Fyn:Fes[plasma membrane]Plexin-A1-4 [plasmamembrane]RhoA/B/C:GTP [plasmamembrane]Fes phosphorylatedCRMP's 1-5 [cytosol]Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP:Rnd1[plasma membrane]CRMP's tetramers[cytosol]p-Plexin-A1-4[plasma membrane]Plexin-A1-4 [plasmamembrane]SEMA6D:PLXNA1:TREM2:DAP12[plasma membrane]Fyn:pCdk5:p53[cytosol]Sema3A:Nrp-1:PlexinA:Fyn [plasmamembrane]RhoA (Mgcofactor):GTP[plasma membrane]pCdk5:p35 [cytosol]Smoothmuscle/non-musclemyosin 2 heavychains [cytosol]NRP1:p-Plexin-A1-4:FYN[plasma membrane]p-Plexin-A1-4[plasma membrane]pPlexin-B1:ErbB2[plasma membrane]pLIMK dimer:HSP-90[cytosol]NRP1:Plexin-A1-4:FYN[plasma membrane]Plexin-A1-4:FYN:FARP2[plasma membrane]NRP1:PlexinA1-4:FYN[plasma membrane]Sema4D:pPlexin-B1:ErbB2:Rac1:Rnd1[plasma membrane]Plexin-A1-4 [plasmamembrane]RAC1-GTP [cytosol]NRP1:p-Plexin-A1-4:FYN[plasma membrane]SEMA7A:Integrinalpha1beta1 [plasmamembrane]PAK homodimer[cytosol]pCdk5:p35 [cytosol]Sema4D:pPlexin-B1:Met[plasma membrane]NRP1:PlexinA1-4:FYN:Cdk5:p53:p-CRMPtetramers [plasmamembrane]Smoothmuscle/non-musclemyosin 2 regulatorylight chains[cytosol]PlexinA1-4:FYN:CDK5:p-CRMPs(S522,S518,T509,T514)[plasma membrane]pCdk5:p35 [cytosol]Active LIMK1[cytosol]Sema3A:NRP-1:pPlexin-A:Fyn:Fes[plasma membrane]SEMA4D:pPlexin-B1:ErbB2complex [plasmamembrane]Plexin-A1-4 [plasmamembrane]PlexinA1-4:FYN:Cdk5:p53:p-CRMPtetramers [plasmamembrane]ActivatedROCK:RhoA/B/C:GTP[plasma membrane]Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP[plasma membrane]SEMA4D dimer [plasmamembrane]NRP1:PlexinA1-4:FYN:pCdk5:p53[plasma membrane]RhoA/B/C [plasmamembrane]pPlexin-B1:Met[plasma membrane]p-Plexin-A1-4[plasma membrane]DAP12:TRIM2 [plasmamembrane]p-Plexin-A1-4[plasma membrane]Sema3A dimer[extracellularregion]NRP1:p-Plexin-A1-4:FYN[plasma membrane]LARG and PDZ-RhoGEF[cytosol]Sema3A dimer[extracellularregion]Phospho-activatedsmoothmuscle/non-musclemyosin 2 [cytosol]SEMA4D:pPlexin-B1:ErbB2complex [plasmamembrane]Sema3A:NP-1:Plexin-A:Fes:CRMP[plasma membrane]SEMA4D dimer [plasmamembrane]Plexin-A1-4:FYN[plasma membrane]SEMA4D dimer [plasmamembrane]GSK3betaphosphorylatedCRMP's 1-5 [cytosol]RAC1-GTP [cytosol]Integrin alpha1beta1[plasma membrane]SEMA7A:PLXNC1[plasma membrane]Sema4D:pPlexin-B1:ErbB2:Rac1:Rnd1[plasma membrane]Sema3A:NRP-1:pPlexin-A:Fyn:Fes[plasma membrane]NRP1:p-Plexin-A1-4:FYN[plasma membrane]Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK[plasma membrane]Active LIMK1[cytosol]Sema3A dimer[extracellularregion]Sema4D:pPlexin-B1:Met:RAC1-GTP[plasma membrane]Cdk5 phosphorylatedCRMP1-5 [cytosol]R-Ras-GDP [plasmamembrane]cytosolcytosolVAV1 Rho/Raceffectors:GTP[cytosol]SEMA3A:PLXND1[plasma membrane]PLXNA2,PLXNA4[plasma membrane]Sema3A:NRP-1:pPlexin-A:Fyn:Fes[plasma membrane]PAK [cytosol]p-CRMP tetramers[cytosol]Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's[plasma membrane]Plexin-A1-4 [plasmamembrane]Smoothmuscle/non-musclemyosin II [cytosol]SEMA4D dimer [plasmamembrane]Sema4D:pPlexin-B1:Met:Rnd1[plasma membrane]NRP1:PlexinA1-4:FYN[plasma membrane]CRMP's 1-5 [cytosol]RhoA/B/C:GTP [plasmamembrane]Cdk5:p35 [cytosol]pPlexin-B1:Met[plasma membrane]Sema3A:NRP-1:pPlexin-A:fyn[plasma membrane]RhoA (Mgcofactor):GDP[plasma membrane]Sema3A:NRP-1:pPlexin-A:fyn[plasma membrane]VAV1 Rho/Raceffectors:GTP[cytosol]SEMA4D dimer [plasmamembrane]Sema3A dimer[extracellularregion]Sema3A dimer[extracellularregion]Rnd1-GTP [cytosol]pCRMP's tetramers(S522,S518,T509,T514)[cytosol]DAP12 dimer [plasmamembrane]Sema3A:Nrp-1:PlexinA:Fyn:pCdk5[plasma membrane]SEMA4D:CD72 [plasmamembrane]SEMA4D dimer [plasmamembrane]cytosolPlexin-A1-4 [plasmamembrane]Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP[plasma membrane]Sema3A:NRP-1:pPlexin-A:Fyn:Fes[plasma membrane]Plexin-A1-4:FYN[plasma membrane]pCRMP's tertramers(Y499) [cytosol]PIP5K1gamma:Talin-1[cytosol]RAC1-GTP [cytosol]Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's(S522,S518,T509,T514)[plasma membrane]Sema3A dimer[extracellularregion]Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP[plasma membrane]Fyn:pCdk5:p53[cytosol]pPlexin-B1:ErbB2[plasma membrane]RAC1-GTP [cytosol]RAC1-GTP [cytosol]Sema4D:Plexin-B1:p190RhoGAP:Rac:Rnd1[plasma membrane]FARP2:PIP5KIgamma[cytosol]pPlexin-B1:Met[plasma membrane]SEMA4A:PLXND1[plasma membrane]Plexin-A1-4:FYN[plasma membrane]pCofilin: ActiveLIMK-1 [cytosol]Smoothmuscle/non-musclemyosin 2 heavychains [cytosol]HSP-90 [cytosol]cytosolSema3A dimer[extracellularregion]Integrin alpha1beta1[plasma membrane]RhoA,B,C:GDP [plasmamembrane]ROCK [cytosol]cytosolPAK [cytosol]Sema4D:pPlexin-B1:Met[plasma membrane]Plexin-B1:ErbB2[plasma membrane]DAP12:TRIM2 [plasmamembrane]p-Plexin-A1-4[plasma membrane]Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's[plasma membrane]pPlexin-B1:Met[plasma membrane]SEMA4D:pPlexin-B1:ErbB2complex [plasmamembrane]Plexin-A1-4 [plasmamembrane]Sema4D:pPlexin-B1:Met:Rnd1[plasma membrane]Sema3A:NRP-1:pPlexin-A:fyn[plasma membrane]Plexin-A1-4:FYN[plasma membrane]R-Ras-GDP [plasmamembrane]PLXNA1:TREM2:DAP12[plasma membrane]SEMA4D dimer [plasmamembrane]Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP[plasma membrane]Sema3A:Nrp-1:PlexinA:Fyn[plasma membrane]Sema3A dimer[extracellularregion]SEMA4D:PTPRC [plasmamembrane]PLXNA1:TREM2:DAP12[plasma membrane]Sema3A:NRP-1:pPlexin-A:fyn[plasma membrane]Fyn:pCdk5:p53[cytosol]SEMA4D dimer [plasmamembrane]Sema3A:Nrp-1:PlexinA:FynSema4D:pPlexin-B1:Met:Rnd1GTP [cytosol]HSP90AA1 [cytosol]RRAS [plasmamembrane]PLXNA3 [plasmamembrane]SEMA6A [plasmamembrane]CRMP1 [cytosol]SEMA4DSEMA3E[extracellularregion]SEMA3A[extracellularregion]ADPR-Ras-GTPPAK2(1-524)[cytosol]RHOB [plasmamembrane]p-Y-PLXNA2(50-1909)[plasma membrane]Sema3A dimerGTP [cytosol]DPYSL3 [cytosol]MYH10 [cytosol]PLXNA4 [plasmamembrane]p-T509,T514,S518,S522-CRMP1[cytosol]p-Y-PLXNA1 [plasmamembrane]GDP [plasmamembrane]LIM KinasesPLXNC1 [plasmamembrane]CDK5R1(1-307)[cytosol]TLN1PLXNA3 [plasmamembrane]MYH11 [cytosol]MYH9 [cytosol]MET [plasmamembrane]RAC1 [cytosol]RAC1 [cytosol]Integrin alpha1beta1ITGB1 [plasmamembrane]PLXNA1 [plasmamembrane]SEMA6A:PLXNA2,PLXNA4MYH11 [cytosol]p-S522-CRMP1[cytosol]ITGA1 [plasmamembrane]ATPp-Y-PLXNA3 [plasmamembrane]PLXNB1 [plasmamembrane]p-S,T508-LIMK1[cytosol]ARHGEF11 [cytosol]SEMA3A:PLXND1p-Y-PLXNA3 [plasmamembrane]ARHGAP35 [cytosol]LIM Kinases,phosphorylatedSEMA6D [plasmamembrane]CFL1NRP1 [plasmamembrane]PLXNA1 [plasmamembrane]ADPFARP2:PIP5KIgammap-Y-PLXNA4 [plasmamembrane]ADPSEMA4D dimerPLXNA2,PLXNA4p-Y-PLXNA2(50-1909)[plasma membrane]p-Y-PLXNA3 [plasmamembrane]p-Y-PLXNA3 [plasmamembrane]ATPRHOA [plasmamembrane]GDPSEMA5APLXNA2(50-1909)[plasma membrane]ATPCRMP's tetramersFYN(2-537) [cytosol]pCofilin: ActiveLIMK-1ATPFARP2 [cytosol]TLN1 [cytosol]TREM2 [plasmamembrane]GTPGDP [plasmamembrane]Sema3A dimerATPFES [cytosol]Sema3A:Nrp-1:PlexinA:Fyn:pCdk5p-S544-DPYSL4[cytosol]MYH14 [cytosol]p-Y15-CDK5 [cytosol]RRAS [plasmamembrane]SEMA3A[extracellularregion]PLXNA1 [plasmamembrane]PIP5K1gamma:Talin-1CDK5R1(1-307)[cytosol]SEMA7AMYL12B(2-172)[cytosol]p-T508-LIMK1[cytosol]FYN(2-537) [cytosol]GTP [cytosol]GDP [plasmamembrane]ITGB1 [plasmamembrane]PLXNA3 [plasmamembrane]p-Y-PLXNA3 [plasmamembrane]PLXNA1 [plasmamembrane]MYL9 [cytosol]Plexin-B1:ErbB2FYN(2-537) [cytosol]GDPATPPiPLXNA3 [plasmamembrane]PiSEMA3A[extracellularregion]PLXNA4 [plasmamembrane]p-Y-DPYSL3 [cytosol]CD72 [plasmamembrane]ADPMYH14 [cytosol]SEMA3A[extracellularregion]RHOA [plasmamembrane]RRAS [plasmamembrane]ERBB2 [plasmamembrane]p-Y-PLXNA2(50-1909)[plasma membrane]PLXNA1 [plasmamembrane]FYN(2-537) [cytosol]Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP:Rnd1RND1 [cytosol]NRP1 [plasmamembrane]p-Y-PLXNB1 [plasmamembrane]SEMA4D [plasmamembrane]NRP1 [plasmamembrane]RND1 [cytosol]SEMA6AADPPLXNA3 [plasmamembrane]Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP'sGTP [cytosol]PLXNA1:TREM2:DAP12PLXNB3ActivatedROCK:RhoA/B/C:GTPSEMA4A [plasmamembrane]GTP [cytosol]RND1 [cytosol]SEMA4D [plasmamembrane]RHOB [plasmamembrane]PLXNA2(50-1909)[plasma membrane]HSP-90PiSEMA3A[extracellularregion]MET [plasmamembrane]p-Y-PLXNA3 [plasmamembrane]Sema4D:pPlexin-B1:MetSema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTPRHOC [plasmamembrane]NRP1p-T19,S20-MYL12B(2-172)[cytosol]ADPPLXNA4 [plasmamembrane]PIP5K1C [cytosol]Mg2+ [plasmamembrane]RhoA/B/C:GTPPLXNA1 [plasmamembrane]DPYSL4 [cytosol]CDK5R1(1-307)[cytosol]SEMA4D [plasmamembrane]PAK2(1-524)[cytosol]Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAKFYN(2-537) [cytosol]GTP [cytosol]RAC1 [cytosol]Sema3A:Nrp-1:PlexinA:FynPLXNA2(50-1909)[plasma membrane]ADPPLXNC1PLXNA2(50-1909)[plasma membrane]ADPp-S534-DPYSL5[cytosol]p-Y-DPYSL5 [cytosol]PLXNA1 [plasmamembrane]p-T509,T514,S518,S522-DPYSL3[cytosol]R-Ras-GDPFESp-Y15-CDK5 [cytosol]GTP [plasmamembrane]RND1 [cytosol]Sema4D:Plexin-B1:p190RhoGAP:Rac:Rnd1RND1 [cytosol]GTP [plasmamembrane]NRP1 [plasmamembrane]ATPNRP1 [plasmamembrane]p-Y-PLXNA4 [plasmamembrane]NRP1:PlexinA1-4:FARP2:FYNNRP1 [plasmamembrane]p-T19,S20-MYL9[cytosol]PLXNA3 [plasmamembrane]ATPRND1 [cytosol]FES [cytosol]GTPRAC1-GTPNRP1 [plasmamembrane]FYN(2-537) [cytosol]p-T509,T514,S518,S522-DPYSL2[cytosol]PLXNA4 [plasmamembrane]TYROBP [plasmamembrane]p-S534-DPYSL5[cytosol]GSK3BRHOB [plasmamembrane]SEMA4D [plasmamembrane]SEMA4D:CD72NRP1 [plasmamembrane]PIP5K1C [cytosol]ERBB2 [plasmamembrane]p-S3-CFL1 [cytosol]FYN(2-537) [cytosol]SEMA4D [plasmamembrane]SEMA4D [plasmamembrane]ATPp-Y-PLXNA1 [plasmamembrane]FYN(2-537) [cytosol]SEMA4D:PTPRCSEMA3A[extracellularregion]Active LIMK1p-Y-DPYSL2 [cytosol]PLXND1 [plasmamembrane]p-Y-CRMP1 [cytosol]SEMA7A [plasmamembrane]PLXNA3 [plasmamembrane]SEMA4D [plasmamembrane]R-Ras-GDPCdk5:p35PAK homodimerATPMET [plasmamembrane]GDP [plasmamembrane]PLXNA4 [plasmamembrane]FES [cytosol]ROCKpLIMK dimer:HSP-90SEMA4D:pPlexin-B1:ErbB2complexSema4D:Plexin-B1:Rac-Rnd1:LARG/PDZ-RhoGEFSEMA6DSEMA7A:Integrinalpha1beta1PAK1 [cytosol]PTPRCADPARHGAP35MYH10 [cytosol]GTP [cytosol]p-Y-PLXNB1 [plasmamembrane]PLXNA1 [plasmamembrane]RhoA (Mgcofactor):GTPPlexin-A1-4:FYNSEMA3A[extracellularregion]SEMA5A [plasmamembrane]Sema3A:NP-1:Plexin-A:Fes:CRMPRAC1 [cytosol]p-S141,T402-PAK2(1-524)[cytosol]RAC1-GDPATPGTP [cytosol]ATPITGA1 [plasmamembrane]MYL6 [cytosol]Smoothmuscle/non-musclemyosin IIFES [cytosol]p-Y-PLXNB1 [plasmamembrane]FYN(2-537) [cytosol]SEMA5A:PLXNB3GTP [cytosol]ARHGEF12 [cytosol]Sema4D:pPlexin-B1:ErbB2:Rac1:Rnd1p-S,T508-LIMK1[cytosol]SEMA7A [plasmamembrane]PLXNA2(50-1909)[plasma membrane]p-Y-PLXNA2(50-1909)[plasma membrane]GTP [cytosol]p-Y-PLXNB1 [plasmamembrane]FES [cytosol]PAKADPSEMA3ENRP1 [plasmamembrane]RAC1 [cytosol]RAC1-GTPRnd1-GTPFYN(2-537) [cytosol]RHOA [plasmamembrane]Rnd1-GTPGTP [plasmamembrane]GDP [cytosol]p-Y-PLXNB1 [plasmamembrane]PLXNB1 [plasmamembrane]GTP [plasmamembrane]p-Y-PLXNA2(50-1909)[plasma membrane]PAK1 [cytosol]SEMA3A[extracellularregion]PLXNB3 [plasmamembrane]p-Y-PLXNA1 [plasmamembrane]ROCK2 [cytosol]DPYSL5 [cytosol]PLXNA1 [plasmamembrane]p-Y-DPYSL4 [cytosol]FARP2SEMA4D [plasmamembrane]FARP2 [cytosol]GTP [cytosol]PLXND1CDK5R1(1-307)[cytosol]MET [plasmamembrane]PLXNA2(50-1909)[plasma membrane]PTPRC [plasmamembrane]PLXNA3 [plasmamembrane]p-S522-DPYSL2[cytosol]ADPGTP [cytosol]p-S144,T423-PAK1[cytosol]RHOA [plasmamembrane]Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAKRRAS [plasmamembrane]SEMA3A[extracellularregion]GTP [cytosol]p-Y-PLXNA1 [plasmamembrane]ADPp-Y15-CDK5 [cytosol]HSP90AB1 [cytosol]NRP1 [plasmamembrane]SEMA4D [plasmamembrane]TREM2 [plasmamembrane]Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP'sSEMA3A[extracellularregion]ROCK1(1-1354)[cytosol]RND1 [cytosol]LIMK1MYH9 [cytosol]Mg2+ [plasmamembrane]SEMA6D:PLXNA1:TREM2:DAP12RhoA,B,C:GDPCDK5 [cytosol]PLXNA4 [plasmamembrane]p-Y-PLXNA4 [plasmamembrane]p-Y-PLXNA1 [plasmamembrane]RAC1 [cytosol]PLXNA2(50-1909)[plasma membrane]p-Y-PLXNA2(50-1909)[plasma membrane]NRP1 [plasmamembrane]PLXNA1 [plasmamembrane]LARG and PDZ-RhoGEFRAC1 [cytosol]PLXNA4 [plasmamembrane]ERBB2 [plasmamembrane]PLXNA2(50-1909)[plasma membrane]p-T508-LIMK1p-Y-PLXNA4 [plasmamembrane]SEMA3A[extracellularregion]ERBB2 [plasmamembrane]GTP [plasmamembrane]FYN(2-537) [cytosol]NRP1 [plasmamembrane]PLXND1NRP1 [plasmamembrane]SEMA4D [plasmamembrane]SEMA4D dimerp-S522-DPYSL3[cytosol]FYN(2-537) [cytosol]SEMA4D [plasmamembrane]SEMA4A:PLXND1PLXNA4 [plasmamembrane]Phospho-activatedsmoothmuscle/non-musclemyosin 2NRP1:PlexinA1-4:FYNPlexin-B1:MetSEMA3A[extracellularregion]FES [cytosol]RhoA (Mgcofactor):GDPCD72RAC1 [cytosol]RHOC [plasmamembrane]ATPp-S544-DPYSL4[cytosol]PLXND1 [plasmamembrane]SEMA7A:PLXNC1R-Ras-GTPp-Y-PLXNA4 [plasmamembrane]RHOC [plasmamembrane]p-Y-PLXNB1 [plasmamembrane]FYN(2-537) [cytosol]TYROBP [plasmamembrane]SEMA3A[extracellularregion]DPYSL2 [cytosol]FYN(2-537) [cytosol]PLXNA2(50-1909)[plasma membrane]Sema4D:pPlexin-B1:Met:RAC1-GTPSema3A:NRP-1:pPlexin-A:Fyn:FesMYL6 [cytosol]RHOA [plasmamembrane]SEMA4Ap-Y-PLXNA4 [plasmamembrane]p-Y-PLXNA1 [plasmamembrane]MET [plasmamembrane]PLXNA4 [plasmamembrane]ADPp-Y-PLXNB1 [plasmamembrane]