Semaphorin interactions (Homo sapiens)

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29, 31, 35, 37, 462, 5, 471, 2811, 16, 18, 2530, 3920, 45363, 24322245, 482282, 12, 266, 74, 19, 489, 4021332310, 3416, 2713, 384, 19, 44, 481715, 421, 14, 282, 41, 4319Integrin alpha1beta1 RhoA/B/CGTP VAV1 Rho/Rac effectorsGTP Plexin-A1-4FYN DAP12TRIM2 LARG and PDZ-RhoGEF PlexinA1-4FYNpCdk5p53 pPlexin-B1Met PLXNA1TREM2DAP12 Sema3A dimer NRP1PlexinA1-4FYN Plexin-A1-4 Integrin alpha1beta1 Sema4DPlexin-B1p190RhoGAPRacRnd1 DAP12 dimer CRMP's 1-5 pCdk5p35 SEMA6DPLXNA1TREM2DAP12 Sema3ANRP-1pPlexin-Afyn Sema3A dimer Plexin-A1-4FYN Sema3ANRP-1pPlexin-AFynFes Sema3A dimer Fes phosphorylated CRMP's 1-5 p-Plexin-A1-4 Sema3ANRP-1pPlexin-Afyn Sema3ANrp-1Plexin AFyn RAC1-GTP FARP2PIP5KIgamma SEMA4D dimer SEMA7AIntegrin alpha1beta1 Sema4DPlexin-B1Rac-Rnd1LARG/PDZ-RhoGEF RAC1-GTP Plexin-A1-4 Nrp-1PlexinAFynCdk5pCRMP's Sema3ANRP-1pPlexin-Afyn Activated ROCKRhoA/B/CGTP Sema3ANRP-1pPlexin-Afyn DAP12TRIM2 Plexin-A1-4 PLXNA2,PLXNA4 Sema4DpPlexin-B1ErbB2Rac1Rnd1 Sema3ANRP-1pPlexin-AFynFes Plexin-B1ErbB2 Rnd1-GTP pCRMP's tetramers p-CRMP tetramers SEMA4DpPlexin-B1ErbB2 complex HSP-90 p-Plexin-A1-4 SEMA7APLXNC1 RAC1-GTP RAC1-GTP GSK3beta phosphorylated CRMP's 1-5 PlexinA1-4FYNCDK5p-CRMPs R-Ras-GDP SEMA4DpPlexin-B1ErbB2 complex Sema3A dimer RhoA Plexin-A1-4 RAC1-GTP Rnd1-GTP Sema4DpPlexin-B1MetRnd1 cytosolPlexin-A1-4 Active LIMK1 Smooth muscle/non-muscle myosin 2 heavy chains NRP1p-Plexin-A1-4FYN pPlexin-B1ErbB2 pPlexin-B1ErbB2 Sema4DpPlexin-B1Met RhoA/B/C RhoA,B,CGDP NRP1p-Plexin-A1-4FYN DAP12 dimer Rnd1-GTP Sema3A dimer p-Plexin-A1-4 Sema3A dimer Cdk5p35 pPlexin-B1Met RhoA/B/C Sema4DpPlexin-B1Met Rnd1-GTP RAC1-GTP SEMA6APLXNA2,PLXNA4 Plexin-B1Met Sema3ANrp-1pPlexinAFynFesRac-1-GTP Sema3ANRP-1pPlexin-Afyn Sema3ANrp-1PlexinARac1-GTPpPAK Sema3ANRP-1pPlexin-AFynFes SEMA4DpPlexin-B1ErbB2 complex pCofilin Active LIMK-1 Smooth muscle/non-muscle myosin 2 heavy chains Sema3ANrp-1pPlexinAFynFesRac-1-GTPRnd1 PAK Phospho-activated smooth muscle/non-muscle myosin 2 Smooth muscle/non-muscle myosin II Sema3ANRP-1pPlexin-AFynFes FynpCdk5p53 Sema3ANrp-1PlexinAFynCdk5pCRMP's Sema3A dimer Smooth muscle/non-muscle myosin 2 regulatory light chains Sema3ANrp-1PlexinAFynpCdk5 Sema4DpPlexin-B1MetRnd1 Plexin-A1-4FYNFARP2 ROCK p-Plexin-A1-4 PAK homodimer cytosolSEMA4D dimer NRP1PlexinA1-4FARP2FYN NRP1PlexinA1-4FYN Plexin-A1-4 pPlexin-B1ErbB2 NRP1p-Plexin-A1-4FYN Sema3ANrp-1PlexinAFynCdk5pCRMP's PAK NRP1Plexin-A1-4FYN Rnd1-GTP cytosolSema3A dimer RhoA SEMA4D dimer pLIMK dimerHSP-90 FynpCdk5p53 NRP1p-Plexin-A1-4FYN NRP1PlexinA1-4FYNpCdk5p53 Plexin-A1-4FYN p-Plexin-A1-4 VAV1 Rho/Rac effectorsGTP pCdk5p35 Sema3A dimer Cdk5 phosphorylated CRMP1-5 Sema4DpPlexin-B1Met SEMA4APLXND1 Sema3ANRP-1pPlexin-AFynFes PIP5K1gammaTalin-1 NRP1p-Plexin-A1-4FYN PlexinA1-4FYNCdk5p53p-CRMP tetramers pPlexin-B1Met Plexin-A1-4FYN RhoA/B/CGTP Sema3ANrp-1PlexinAFyn FynpCdk5p53 Sema4DpPlexin-B1Met SEMA3APLXND1 cytosolSema3ANRP-1pPlexin-Afyn CRMP's tetramers SEMA4D dimer R-Ras-GTP SEMA5APLXNB3 SEMA4DPTPRC Sema3ANrp-1pPlexinAFynFesRac-1-GTP SEMA4D dimer SEMA4DCD72 Sema3A dimer RAC1-GTP cytosolpCdk5p35 Plexin-A1-4 Sema4DpPlexin-B1MetRAC1-GTP Sema3ANrp-1pPlexinAFynFesRac-1-GTP Active LIMK1 SEMA4D dimer SEMA4D dimer Phosphorylated smooth muscle/non-muscle myosin 2 regulatory light chains Sema3ANrp-1pPlexinAFynFesRac-1-GTP p-2Y-PAK RhoA/B/C Sema3ANRP-1pPlexin-AFynFes Plexin-A1-4 R-Ras-GTP NRP1p-Plexin-A1-4FYN pCRMP's tertramers Sema3A dimer SEMA4D dimer Sema4DpPlexin-B1ErbB2Rac1Rnd1 R-Ras-GDP Sema3ANP-1Plexin-AFesCRMP NRP1PlexinA1-4FYNCdk5p53p-CRMP tetramers Sema3A dimer SEMA4D dimer p-Plexin-A1-4 RAC1-GDP Sema3A dimer PLXNA1TREM2DAP12 pPlexin-B1Met Sema3ANrp-1PlexinARac1-GTPPAK RHOB NRP1 NRP1 p-Y-PLXNA1 DPYSL4 FES CD72 p-Y-PLXNA4 ITGA1 Sema3ANrp-1PlexinAFynCdk5pCRMP'sARHGAP35NRP1 ROCK2 PLXNA3 Rnd1-GTPp-Y-PLXNA2p-Y-PLXNA4 LIMK1NRP1 RND1 p-S534-DPYSL5 PLXNA2,PLXNA4RRAS Sema3ANRP-1pPlexin-AFynFesMg2+ SEMA3A GDP RhoA,B,CGDPADPPLXNA2R-Ras-GDPSEMA4D GDP RAC1 SEMA3A GTP MET SEMA4D ADPPIP5K1C MYL6 LARG and PDZ-RhoGEFp-Y15-CDK5 RHOB PLXNB1 p-Y-PLXNA3 RAC1-GDPRhoA GTP PLXNA2FYNSEMA3A MYL9 p-S,T508-LIMK1 ATPGTP ARHGEF12 PLXNA1 GDPp-Y-PLXNB1 PLXNA3 TYROBP PLXNA4 MYH14 GTP MET NRP1 RHOA p-Y-PLXNA3 PLXNA4 PLXNA4 ADPADPActive LIMK1SEMA4D Sema3ANrp-1pPlexinAFynFesRac-1-GTPCDK5R1p-Y-PLXNA3 ERBB2 p-S544-DPYSL4 SEMA3EGTP FES ATPGDP p-T508-LIMK1 p-T509,T514,S518,S522-CRMP1 PiATPSEMA7APlexin-B1MetHSP90AA1 p-S522-DPYSL3 Sema3ANrp-1PlexinAFynpCdk5PLXNB1 RRAS MYH9 Sema3ANP-1Plexin-AFesCRMPPAK2ATPp-T509,T514,S518,S522-DPYSL2 SEMA3A p-Y-PLXNA4 ATPPLXND1 FYNIntegrin alpha1beta1ITGA1 RHOC FARP2GTP SEMA6DPLXNA1TREM2DAP12GTP HSP-90MYH11 PIP5K1gammaTalin-1CD72PLXNA1 Sema3ANrp-1PlexinARac1-GTPpPAKp-Y-PLXNA3 ATPPLXNA1 SEMA7A PAK2MET PIP5K1C FES p-Y-DPYSL5 ATPActivated ROCKRhoA/B/CGTPSema4DpPlexin-B1MetRnd1SEMA3A p-T19,S20-MYL9 MYH10 p-Y-PLXNB1 Sema4DPlexin-B1Rac-Rnd1LARG/PDZ-RhoGEFERBB2 PLXNA1 DPYSL2 FES PLXNA1 SEMA4D PLXNA2RAC1 Plexin-A1-4FYNp-Y-PLXNA2MET ARHGAP35 CRMP1 ADPCFL1GDPp-Y-PLXNB1 RAC1 p-Y-CRMP1 ADPRHOB PTPRC FYNp-S,T508-LIMK1 Plexin-B1ErbB2GTPATPFYNp-T19,S20-MYL12BPLXNA2ADPGTP SEMA4DpPlexin-B1ErbB2 complexp-Y-PLXNB1 GTP Sema3ANrp-1pPlexinAFynFesRac-1-GTPRnd1p-Y-PLXNA2SEMA6A ITGB1 p-S522-DPYSL2 PLXNA4 FESGTP SEMA4DPTPRCRND1 Sema3A dimerp-Y-PLXNA2p-S144,T423-PAK1 RAC1 ARHGEF11 SEMA4D dimerPLXNA2R-Ras-GTPPLXNA1TREM2DAP12SEMA3A RAC1 PLXNC1RhoA ATPRHOA FYNR-Ras-GDPSema3ANrp-1PlexinARac1-GTPPAKPLXNA3 GTP NRP1 Smooth muscle/non-muscle myosin IISEMA6APLXNA2,PLXNA4SEMA5APLXNB3PLXND1 SEMA4D FYNITGB1 p-Y-PLXNA3 ATPATPFYNFARP2PIP5KIgammaPLXNA1 FYNp-Y-PLXNA1 p-Y-PLXNA1 RHOA GSK3BSema3ANrp-1PlexinAFynCdk5pCRMP'sPLXNC1 SEMA7APLXNC1SEMA4D RND1 SEMA3A pLIMK dimerHSP-90p-Y15-CDK5 pCofilin Active LIMK-1p-Y-DPYSL4 PLXNA1 SEMA4D PLXNA3 FES GTP DPYSL3 MYL12BLIM Kinasesp-S3-CFL1 NRP1PLXNA3 p-Y-PLXNA1 R-Ras-GTPPLXNA1 PLXNA3 p-Y-PLXNA2RAC1 RHOC p-Y-PLXNA1 SEMA3A TYROBP PAKp-Y15-CDK5 TLN1RAC1 GTP PLXNA1 p-Y-PLXNB1 GTP Cdk5p35MYH11 PTPRCRHOA FARP2 ADPGTP MYH14 SEMA3A SEMA4DCD72ATPPLXNA3 PLXNA2SEMA6DPLXNA4 SEMA4APLXND1SEMA4D NRP1 PLXNA4 FES PLXNA4 NRP1 MET p-S141,T402-PAK2SEMA3A PAK1 LIM Kinases, phosphorylatedPiRhoA/B/CGTPADPTREM2 PLXNA2CDK5 PLXNA1 RAC1-GTPp-Y-DPYSL2 p-S534-DPYSL5 SEMA7A SEMA3A ADPGTP p-Y-PLXNA2FYNSEMA4D dimerSEMA6ANRP1PlexinA1-4FARP2FYNROCK1Sema3A dimerRND1 SEMA5APLXND1CDK5R1ROCKp-Y-PLXNA4 FYNGDP NRP1 HSP90AB1 p-Y-PLXNA4 PLXNA4 FYNTREM2 PLXNB3 DPYSL5 SEMA3E ADPSEMA4A Pip-Y-PLXNB1 ADPNRP1 RRAS GTP Sema4DpPlexin-B1ErbB2Rac1Rnd1Sema4DpPlexin-B1MetCDK5R1SEMA4D p-Y-PLXNA4 GTP p-Y-PLXNB1 PLXNA2PLXNA3 PLXNB3NRP1 Sema3ANrp-1PlexinAFynPLXND1ATPSEMA4D SEMA3A SEMA3A MYH10 p-Y-PLXNA3 CRMP's tetramersTLN1 RHOA SEMA4DMYL6 GTPSEMA5A p-Y-PLXNA1 FARP2 MYH9 SEMA3APLXND1RND1 SEMA4D Sema3ANrp-1Plexin AFynERBB2 Rnd1-GTPSema4DPlexin-B1p190RhoGAPRacRnd1p-S522-CRMP1 Mg2+ FYNNRP1PlexinA1-4FYNRAC1-GTPSEMA7AIntegrin alpha1beta1PAK homodimerSema4DpPlexin-B1MetRAC1-GTPSEMA4APLXNA2p-T508-LIMK1SEMA6D RND1 ADPNRP1 RND1 RHOC p-T509,T514,S518,S522-DPYSL3 FYNPAK1 ERBB2 p-S544-DPYSL4 PLXNA4 RRAS GDP RAC1 FYNCDK5R1NRP1 p-Y-DPYSL3 Phospho-activated smooth muscle/non-muscle myosin 2