ABC-family proteins mediated transport (Homo sapiens)

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6, 31, 6520, 34, 38, 51, 74...30, 8023, 46322, 35, 6644, 591, 17, 53, 764, 5014, 26, 3310, 11, 41, 56, 6115367, 3242, 6821, 52, 58, 60, 6221, 37, 40, 48, 6713, 815, 25, 27, 644412, 13, 24, 43, 44, 57...2, 8, 7118, 45, 73289, 16, 54, 55, 72...8147, 492910, 11, 41, 56, 611, 17, 53, 7639, 63peroxisomal matrixcytosoltransport vesiclelysosomal lumenendoplasmic reticulum lumenmitochondrial matrixlamellar bodyH2OABCG4 BDG RNF185 ABCD2 PSMB8 PSMA5 ADPH2OABCC6 ABCG1 dimerPC RNF5 ABCB7(23-752) PG PCCHOLPSMA7 ABCC8 UBC(457-532) PSME2 Cl-ABCD1 porphyrinPSMA1 ABCA7-dependentphospholipidsUBC(153-228) UBA52(1-76) ABCC2 ABCC10 CHOL K+BMG EIF2S3 ABCC11 PSMC4 DERL2 H2OLCFAUBC(1-76) SPHM ATPADPatRALABCB6 UBA52(1-76) UBB(153-228) Ub-misfolded nascentCFTRLCFAUBB(153-228) SPHM lipidsRPS27A(1-76) VCP UBC(1-76) DERL1 APOA1(25-266) Heme transportersH2OUBC(533-608) ADPPSMA4 UBB(77-152) UBB(77-152) ERLIN2 UBC(1-76) UBB(77-152) ATP23mer peptideUBC(77-152) PiUBC(305-380) PSMC6 ABCCsPSMD14 PiCFTR G551D UBA52(1-76) UBC(153-228) ABCC5 ERLIN1 UBC(153-228) HCO3-Ub-misfolded nascentCFTR:ERAD complexUBC(381-456) SEL1L ABCC4 heme26S proteasomeBDG UBC(229-304) ABCD3 PiH2OPSMD3 EIF2S1:EIF2S2:EIF2S3UBC(533-608) misfolded CFTRPC H2OABCC9 UBB(1-76) H2OABCA5hemeCl-PSMB6 OS9 H2Oa xenobioticUBC(609-684) ABCG8 PiH2OH2OEIF2S1 PSMB4 PiADPCHOLABCD2 ABCA7 ADPRPS27A(1-76) ERLEC1 H2OUBC(609-684) CHOL ADPATPABCC2ADPH2OSEL1L misfolded CFTR UBC(77-152) PiADPPCPSMB1 PSMC3 ABCG5:ABCG8UBC(381-456) UBC(457-532) PC ABCD1 PiATPADPMTABC3 dimerABCF1:EIF2S1:EIF2S2:EIF2S3PSMA3 PSMA8 UBC(609-684) UBC(229-304) PSME4 ABCD1-3 dimersIvacaftorPSMC2 PiPiATPKCNJ11:ABCC9PiRNF185 CFTR G551DPSMB11 ERLEC1 EIF2S2 UBC(229-304) ATPUBC(609-684) PiADPIvacaftor ADPATPADPUBC(533-608) ABCA7-1:ApoA1complexPSME3 PSMD7 PSMD10 ATPABCA8 CFTRABCF1UBB(1-76) CFTRUBB(153-228) ADPsterolsERLIN2 PC EIF2S3 misfolded CFTR UBC(381-456) UBC(305-380) ABCB4PiUBC(1-76) UBC(229-304) PSMB2 CHOLH2OUBB(1-76) ATPABCB8 OS9 CHOLPEX19 UBC(305-380) UBB(1-76) H2Oorganic anionOS9 phytosterols ABCB9 dimerADPADPPC, PGRPS27A(1-76) ABCA3misfolded CFTR:ERADcomplexATPH2OK+SHFM1 porphyrinATPVCP ABCA10 PSMC1 ABCG4 dimerPiABCA6 UbPSMB7 DERL3 H2OH2OUBA52(1-76) ERLIN1 PSMD13 PG CHOLBMG,BDGATPDERL3 ATPABCC9 ABCG1 BMG HCO3-phytosterols ADPUBB(153-228) RNF185 DERL1 UBB(77-152) organic anionPSMB10 UBC(457-532) UBC(457-532) 23mer peptidePEX3ABCF1 ADPPSME1 ABCG5 ABCA7-dependentphospholipidsPSMD6 PSMC5 VCP ABCA8/B1/B5ERLIN2 ABCA4ERAD complexRPS27A(1-76) ATPERLIN1 lipidsUbPSMD9 RNF5 PSMD11 CHOLPSMD2 PiPiKCNJ11 DERL1 ABCC1 ATPADPUBC(77-152) PSMB9 PC, PGmisfolded CFTR RNF5 PSMD5 H2OSEL1L PSMD4 ABCD3 ERLEC1 EIF2S2 ABCA2 ABCB9 DERL3 ATPPSMB5 PEX19:ABCD1/2/3a xenobioticPSMD8 PSMA2 PiABCA9 PSMD1 Cl-CHOLPiCFTR UBC(153-228) sterolsATPUBC(533-608) PEX19PiBMG,BDGPiPSMD12 PSMF1 ATPUBC(77-152) ABCB10 ABCB5 EIF2S1 UBC(381-456) PSMA6 ABCA12UBC(305-380) ADPIvacaftor:CFTR G551DABCC3 atRALDERL2 DERL2 ABCB1 PSMB3 ABCA cholesteroltransporters19, 6969