ABC-family proteins mediated transport (Homo sapiens)

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9, 19, 6612, 17, 24, 375635, 753, 5272, 7714, 185, 29, 36, 40, 70...20, 63, 672, 22, 25, 27, 64...48, 61505526, 28, 41, 58, 6043, 54497, 331, 16, 23, 31, 4547, 51, 808, 10, 1365, 6862, 71, 763, 15, 21, 30, 38...26, 28, 41, 58, 60524612, 17, 24, 376, 11, 34, 4450, 731, 39, 53, 57, 7932lamellar bodytransport vesicleperoxisomal matrixlysosomal lumencytosolmitochondrial matrixendoplasmic reticulum lumenH2OCFTRUBC(1-76) UBC(609-684) UbUBC(305-380) Cl-H2OERLIN2 PiPSMD4 ADPPiERLIN1 ABCA7 UBC(229-304) ADPK+ADPABCB6 EIF2S2 EIF2S3 SEL1L PiABCG4 UBB(77-152) RPS27A(1-76) DERL1 UBC(229-304) UBC(457-532) ATP23mer peptideCHOLATPRNF185 CFTR ADPCHOLPSMB8 misfolded CFTR ERLIN2 ATPABCC9 ATPABCB5 RNF5 ABCA7-dependentphospholipidsUBC(305-380) UBC(381-456) PSMB7 ATPphytosterols UBC(305-380) UBC(229-304) PSMD12 PSMC1 PiCHOL LCFAH2OUBC(153-228) misfolded CFTR PSMA5 ABCB7(23-752) LCFAmisfolded CFTR ABCC10 PEX3lipidsIvacaftor:CFTR G551DPSMC2 PiKCNJ11 H2OPC ABCF1 ABCA5PSMA1 DERL1 HCO3-ABCC4 UBC(457-532) Cl-ABCF1UBC(305-380) Cl-APOA1(25-266) PSMC5 SEL1L UBB(1-76) RPS27A(1-76) ABCD2 PC PiPSMD6 UBB(1-76) BMG,BDGADP23mer peptideRNF5 PiH2OUBA52(1-76) ATPSPHM Ub-misfolded nascentCFTRPiUBC(77-152) CHOL organic anionPiABCC2 ADPPSME1 PSMD9 PSMD10 PC, PGABCA7-1:ApoA1complexCHOLhemeOS9 KCNJ11:ABCC9UBB(153-228) DERL3 PiADPABCG5 H2OhemeH2OABCB1 ABCA2 H2ODERL3 PiBDG PSMD11 UBB(153-228) ATPH2OPSMD8 ABCD1 ABCC5 EIF2S1 ABCA8 UBB(153-228) ATPABCD1 H2OABCC9 PSMA4 ERLEC1 UBC(153-228) RNF185 K+ABCC11 UBA52(1-76) VCP PEX19:ABCD1/2/3CFTRH2OABCA6 ADPPSMB6 PSMC6 OS9 UBC(609-684) UBC(533-608) ABCA4PiPiADPRPS27A(1-76) UBB(77-152) ABCG8 PSMB10 PSMD3 ATPH2OADPDERL1 H2OABCG4 dimerUBC(229-304) PSME2 PSMD14 ABCA7-dependentphospholipidsPSMA6 PC, PGPSMD2 Ub-misfolded nascentCFTR:ERAD complexPCABCD2 EIF2S2 UBA52(1-76) UBC(609-684) PSMA8 ABCC2UBC(77-152) ATPUBC(533-608) PSMD1 atRALH2OABCA cholesteroltransportersPSME4 ADPPSMB11 H2OERLEC1 PiUBC(381-456) BMG ABCG1 dimerERLIN1 DERL2 EIF2S3 ADPABCF1:EIF2S1:EIF2S2:EIF2S3UbADPUBC(153-228) MTABC3 dimerH2OABCC3 Ivacaftor ADPVCP BMG,BDGlipidsPiPEX19 ABCA8/B1/B5ADPatRALPSMF1 ERAD complexCHOLPG SEL1L RNF185 CHOLPSME3 PSMA2 ADPPSMB3 PSMC4 phytosterols CFTR G551DUBC(153-228) PSMB4 SHFM1 ABCG1 DERL3 HCO3-misfolded CFTR:ERADcomplexUBB(153-228) ABCG5:ABCG8ATPERLIN2 UBC(381-456) ABCC1 ATPporphyrinATPUBC(533-608) PiDERL2 ATPABCB9 dimerADPPiHeme transportersUBB(77-152) a xenobioticERLEC1 ABCA12PC DERL2 UBC(609-684) 26S proteasomeABCB4ABCB8 UBA52(1-76) UBC(457-532) PCBDG PSMB1 ABCD1-3 dimersPSMD7 UBB(77-152) OS9 ATPPSMB9 PiABCA3UBC(1-76) organic anionABCA9 ABCD3 H2OH2Omisfolded CFTRPSMA7 PSMB5 sterolsa xenobioticPSMD13 ATPUBC(1-76) PSMC3 ERLIN1 ABCCsABCD3 porphyrinABCB9 PG PSMD5 BMG SPHM CHOLRPS27A(1-76) UBB(1-76) CFTR G551D ABCA10 PEX19sterolsUBC(457-532) ABCC6 ADPUBC(77-152) PC PiPSMB2 IvacaftorEIF2S1 ATPUBC(77-152) UBB(1-76) PSMA3 UBC(533-608) ABCB10 EIF2S1:EIF2S2:EIF2S3CHOLUBC(381-456) VCP ADPATPRNF5 UBC(1-76) 594, 59