Folate Metabolism (Homo sapiens)

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329, 33035, 33030, 49, 145, 150, 185...133, 264109, 229, 273, 317, 3283285, 2792247486, 169117260140, 178, 23064126, 304is composed ofCleavageBiomarker forInhibitionProtein tyrosine nitrationStimulationLipid peroxidationSelenium statusMicronutrientsOverarching processOther proteinsReactionTranscription factorBindingProcess or metabolism involved in Se PathwayCatalysisLipoprotein melabolismNegative EffectGlycogenesisCofactorsNecessary stimulationMetabolitesLEGENDProtein*Cofactor conversionProtein with polymorphismProstaglandins metabolismSelenoproteinsEnzymesConversionFrom intracellular part to the plasmaIntracellularNovo purine biosynthetic pathwayMethylation reactionsDNA oxidationApoptosisPlasmaNFkB2FOLR38-Isoprostaglandin F2aThromboxane A2SLC19A1FOLR4PGF2aThromboxane B2FOLR1MCP1MCP1PGE2SLC46A1NFkB1p53F2-IsoprostaneThromboxane B2PGE2F2-IsoprostanePGE1FOLR2RELAPGF2a8-Isoprostaglandin F2aPGE11252316718, 30, 64, 68, 178...2312167, 19246, 23246, 209, 327263212112546, 17626326320946, 23246, 17621209263MTR*MTHFD1*AHCYMSR*SHMTDHFRMATMTHFD2132, 219, 241304, 32464223, 3049772, 10730496, 107, 142, 302CBS151, 302NADP+NADP+NADP+NADP+NADP+NADP+NADP+MPONOSMPOCatalase236, 32826, 115, 160, 31719226, 115, 160, 317CysteineCysteineThrombinFactor VIIPLGThrombintPAPAI-1PLGPAI-1Factor VIItPA11111114, 2751114, 27514, 22514, 2251111GPX 4H2O2(11S)-hydroxymethylene-THF10-Formyl-THF5,10-Methylene-THFDihydrofolate5-Formyl-THFGAR(11R)-hydroxymethylene-THFFGAR5,10-Methenyl-THF304219, 304304219304304304126, 304126, 3045-methyl-THFFolate5-methyl-THFFolate21, 64, 125, 161, 175...96, 219219SOD3SOD3RFK297H2OGPX 3GPX 3CTH302Heme151, 236, 328THF219NADPHNADPHNADPHNADPHNADPHNADPHNADPHGPX 6ManganeseManganeseFolic acidFolic acid142, 219, 278142, 219, 278GPX 2GPX 1RNS74, 328MTHFR*SHMTGARTMTHFS142, 219304126, 304304HomocysteineHomocysteine49, 96, 125, 140, 225...225SOD1Pyridoxal 5'-phosphatePyridoxal 5'-phosphate63, 192, 26663, 266L-ArginineSerineGlycineGlycine223, 304223, 304223, 304253VLDLoxLDLTAGHDL/SAASRB1SAA1TAGSAA4APOA1-NO2TyrCholesterolHDLHDL-CACTACTFMNLDLAPOA1LDLAPOBCholesterolSAA2APOBVLDLHDL-CoxLDLVLDL-TAGHDLABCA1APOA1HDL/APOA1VLDL-TAGVLDL/APOBLDLRSAA326, 86, 138, 175, 28226, 86, 138, 282169, 19544169169, 175169, 195202169169, 19516926, 86, 138, 2821691696666, 2946666, 29466666666169, 202169, 195169, 195, 202169, 17527226, 86, 138, 175, 28219616990, 1961696690, 196O22798-OHdGCob(I)alaminFAD8-OHdGFADCob(I)alaminCob(II)alamin72, 107, 21726072, 107, 21710727226072, 107ADPADPChlorineMagnesiumMagnesiumChlorineCystathionineS-nitrosohomocysteine289SOD2Serine223, 304ATPZincZincNOO3NONO2HNO2HOCl115, 160115, 160, 178, 289IL1BFibrinogenD-dimerFibrinIL1BD-dimerHbA1cCSF1IL10IL2IL10IL4IL6TNFasICAM-1ALBIL6HBA1ALBIL4IFNgCRPINSRFibrinogenHbA1cIFNgHBBCSF1INSTNFaFibrinIL2INS145, 229, 283, 30618, 228222, 28311, 189224, 294, 30611, 275185, 2291823468, 221, 229, 3291858014518, 22815068, 2211505, 138, 161, 192, 206...224, 294, 306222234238, 3062149, 283, 325801821234234329, 33011, 18911, 275Riboflavin243O2Methionine S-Adenosylhomocysteine S-Adenosylmethionine S-AdenosylhomocysteineMethionine S-Adenosylmethionine107, 219, 27164, 107, 219, 271270104, 21996, 219, 270104, 219ADPNitrotyrosineTetrahydrobiopterinNitrotyrosineONOO/ONOOH7425374ATPATPFructosamineGlucoseFructosamineGlucose224, 2348080224, 234IronIron318318FLAD1159, 297FGAFGBFGG