Nicotine Activity on Dopaminergic Neurons (Homo sapiens)

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  1. martin, grady; ''mine'';, 1999 PubMed Europe PMC
  2. Klein TE, Chang JT, Cho MK, Easton KL, Fergerson R, Hewett M, Lin Z, Liu Y, Liu S, Oliver DE, Rubin DL, Shafa F, Stuart JM, Altman RB; ''Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base.''; Pharmacogenomics J, 2001 PubMed Europe PMC
  3. Eiden LE, Schäfer MK, Weihe E, Schütz B; ''The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine.''; Pflugers Arch, 2004 PubMed Europe PMC
  4. Cartier EA, Parra LA, Baust TB, Quiroz M, Salazar G, Faundez V, Egaña L, Torres GE; ''A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles.''; J Biol Chem, 2010 PubMed Europe PMC
  5. Kaltenbach M; ''[Conservative therapy of coronary heart disease].''; Verh Dtsch Ges Kreislaufforsch, 1975 PubMed Europe PMC


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106663view21:22, 12 September 2019KhanspersModified description
106180view12:07, 16 August 2019MaintBotHMDB identifier normalization
105664view05:18, 10 August 2019KhanspersModified description
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47511view10:28, 24 March 2012Madhu RohiniPeriodical save, work in progress
45361view20:49, 7 October 2011KhanspersOntology Term : 'nicotine pathway' added !
45360view20:49, 7 October 2011KhanspersOntology Term : 'dopaminergic neuron' added !
42610view21:27, 10 April 2011AlexanderPicoadded biochemical and functional complex for DA synth and accumulation in vesicles, plus ref
42606view21:15, 10 April 2011AlexanderPicoadded ref for SLC18A2 function
42605view21:14, 10 April 2011AlexanderPicofixed localization of dopamine biosyn and vesicle accumulation
41032view23:15, 1 March 2011MaintBotRemoved redundant pathway information and comments
38611view00:02, 22 September 2010KhanspersModified categories
38610view00:02, 22 September 2010KhanspersChanged title
38481view18:22, 17 September 2010AlexanderPicoattribution listed in Sources
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38374view15:20, 5 September 2010BoghogAdded reference
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External references


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NameTypeDatabase referenceComment
ADCY2GeneProduct108 (Entrez Gene)
ATPMetaboliteHMDB00538 (HMDB)
CDK5GeneProduct1020 (Entrez Gene)
CHRNA3GeneProduct1136 (Entrez Gene)
CHRNA4GeneProduct1137 (Entrez Gene)
CHRNA5GeneProduct1138 (Entrez Gene)
CHRNA6GeneProduct8973 (Entrez Gene)
CHRNB2GeneProduct1141 (Entrez Gene)
Ca++MetaboliteHMDB00464 (HMDB)
DDCGeneProduct1644 (Entrez Gene)
DOPAMetaboliteHMDB00181 (HMDB)
DRD2GeneProduct1813 (Entrez Gene)
DRD3GeneProduct1814 (Entrez Gene)
DRD4GeneProduct1815 (Entrez Gene)
DopamineMetaboliteHMDB00073 (HMDB)
GNAI1GeneProduct2770 (Entrez Gene)
GNB1GeneProduct2782 (Entrez Gene)
GNG2GeneProduct54331 (Entrez Gene)
K+MetaboliteHMDB00586 (HMDB)
KCNK3GeneProduct3777 (Entrez Gene)
KCNK9GeneProduct51305 (Entrez Gene)
Na+MetaboliteHMDB00588 (HMDB)
NicotineMetaboliteHMDB01934 (HMDB)
PPP1CAGeneProduct5499 (Entrez Gene)
PPP1R1BGeneProduct84152 (Entrez Gene)
PRKACAGeneProduct5566 (Entrez Gene)
SLC18A2GeneProduct6571 (Entrez Gene)
SNARE ComplexGeneProduct
THGeneProduct7054 (Entrez Gene)
TyrosineMetaboliteHMDB00158 (HMDB)
cAMPMetaboliteHMDB00058 (HMDB)

Annotated Interactions

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