Valine, leucine and isoleucine degradation (Caenorhabditis elegans)

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Valine, leucine and isoleucine biosynthesisbcat-1K09H11.1Thiamine pyrophosphateech-1Isobutyryl-CoAacdh-10ech-7acdh-8K09H11.13-Hydroxyisovaleryl-CoATransketolase2-Methylacetoacetyl-CoALipoamide-ER-Methylmalonyl-CoAivd-1TransketolaseL-ValineMethacrylyl-CoAech-3Lipoamide-ET02G5.7ech-1Y71G12B.10Dihydrolipoamide-Etag-173TransketolaseLLC1.3ard-1gta-1F54C8.1ech-5(S)-3-Hydroxyisobutyric acidL-LeucineF53A2.7ZK669.4acdh-7bcat-1S-(3-Methylbutanoyl)-dihydrolipoamide-EAcetyl-CoAZK669.4ZK669.4Acetoacetyl-CoAB0272.3Tiglyl-CoAacdh-7acdh-10K09H11.1ech-2Y44A6D.5ech-5S-Methylmalonic acid semialdehydeKetoleucinea-Ketoisovaleric acidtag-173ech-53-Methylcrotonyl-CoAhacd-1Dihydrolipoamide-EAcetoacetic acidtag-173Propionyl-CoAech-2ech-9ech-63-Hydroxy-3-methylglutaryl-CoALipoamide-EIsovaleryl-CoAT08B2.7acdh-3ech-6Transketolaseech-13-Methylglutaconyl-CoAY44A6D.5(S)-3-Hydroxyisobutyryl-CoAS-(2-Methylbutanoyl)-dihydrolipoamide-EF25B4.6Thiamine pyrophosphateS-Methylmalonyl-CoAF32B6.2L-IsoleucineMethylmalonic acid2-Methyl-1-hydroxybutyl-ThPPBranched-chain fatty acidkat-1T08B2.7ech-3acdh-83-Aminoisobutanoic acidech-7acdh-73-Methyl-1-hydroxybutyl-ThPPpcca-1pccb-1T08B2.7S-2-Methylbutanoyl-CoASuccinyl-CoAThiamine pyrophosphateS-3-Methyl-2-oxopentanoic acid2-Methyl-3-hydroxybutyryl-CoAS-(2-Methylpropionyl)-dihydrolipoamide-Eech-7acdh-8ech-6tag-173Transketolasebcat-1C05C10.3acdh-10ech-2Dihydrolipoamide-ELLC1.3LLC1.3B0303.3T02G5.42-Methyl-1-hydroxypropyl-ThPPech-3acdh-3Transketolasetag-173ech-8Y44A6D.5tag-173


Description

No description

Quality Tags

Ontology Terms

 

Bibliography


History

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CompareRevisionActionTimeUserComment
34744view22:49, 13 January 2010KhanspersDeleted pathway: duplicate
33726view15:41, 8 December 2009Pieter Giesbertzfixed datapoints from KEGG
33725view15:29, 8 December 2009Pieter GiesbertzPeriodical save, work in progress
33724view15:19, 8 December 2009Pieter GiesbertzPeriodical save, work in progress
33723view15:09, 8 December 2009Pieter GiesbertzPeriodical save, work in progress
33722view14:59, 8 December 2009Pieter Giesbertzmanually improving KEGG pathway
33719view13:39, 8 December 2009Pieter Giesbertzmanually improving KEGG pathway
33718view12:48, 8 December 2009Pieter GiesbertzNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
(S)-3-Hydroxyisobutyric acidMetaboliteHMDB00023 (HMDB)
(S)-3-Hydroxyisobutyryl-CoAMetaboliteHMDB01052 (HMDB)
2-Methyl-1-hydroxybutyl-ThPPMetaboliteHMDB12310 (HMDB)
2-Methyl-1-hydroxypropyl-ThPPMetaboliteHMDB06866 (HMDB)
2-Methyl-3-hydroxybutyryl-CoAMetaboliteHMDB01356 (HMDB)
2-Methylacetoacetyl-CoAMetaboliteHMDB01157 (HMDB)
3-Aminoisobutanoic acidMetaboliteHMDB03911 (HMDB)
3-Hydroxy-3-methylglutaryl-CoAMetaboliteHMDB01375 (HMDB)
3-Hydroxyisovaleryl-CoAMetaboliteHMDB06870 (HMDB)
3-Methyl-1-hydroxybutyl-ThPPMetaboliteHMDB06865 (HMDB)
3-Methylcrotonyl-CoAMetaboliteHMDB01493 (HMDB)
3-Methylglutaconyl-CoAMetabolite6102 (PubChem)
Acetoacetic acidMetaboliteAcetoacetic acid (Wikipedia)
Acetoacetyl-CoAMetaboliteHMDB01484 (HMDB)
Acetyl-CoAMetaboliteHMDB01206 (HMDB)
B0272.3GeneProductB0272.3 (Ensembl C. elegans)
B0303.3GeneProductB0303.3 (Ensembl C. elegans)
Branched-chain fatty acidMetabolite8270 (PubChem)
C05C10.3GeneProductC05C10.3 (Ensembl C. elegans)
Dihydrolipoamide-EMetaboliteHMDB06879 (HMDB)
F25B4.6GeneProductF25B4.6 (Ensembl C. elegans)
F32B6.2GeneProductF32B6.2 (Ensembl C. elegans)
F53A2.7GeneProductF53A2.7 (Ensembl C. elegans)
F54C8.1GeneProduct186222 (Entrez Gene)
Isobutyryl-CoAMetaboliteHMDB01243 (HMDB)
Isovaleryl-CoAMetaboliteHMDB01113 (HMDB)
K09H11.1GeneProduct178962 (Entrez Gene)
KetoleucineMetaboliteHMDB00695 (HMDB)
L-IsoleucineMetaboliteHMDB00172 (HMDB)
L-LeucineMetaboliteHMDB00687 (HMDB)
L-ValineMetaboliteHMDB00883 (HMDB)
LLC1.3GeneProductLLC1.3 (Ensembl C. elegans)
Lipoamide-EMetaboliteHMDB06877 (HMDB)
Methacrylyl-CoAMetaboliteHMDB01011 (HMDB)
Methylmalonic acidMetaboliteHMDB00202 (HMDB)
Propionyl-CoAMetaboliteHMDB01275 (HMDB)
R-Methylmalonyl-CoAMetaboliteHMDB02255 (HMDB)
S-(2-Methylbutanoyl)-dihydrolipoamide-EMetaboliteHMDB06869 (HMDB)
S-(2-Methylpropionyl)-dihydrolipoamide-EMetaboliteHMDB06868 (HMDB)
S-(3-Methylbutanoyl)-dihydrolipoamide-EMetaboliteHMDB06867 (HMDB)
S-2-Methylbutanoyl-CoAMetabolite47205293 (PubChem)
S-3-Methyl-2-oxopentanoic acidMetabolite3940 (PubChem)
S-Methylmalonic acid semialdehydeMetaboliteHMDB02217 (HMDB)
S-Methylmalonyl-CoAMetaboliteHMDB02310 (HMDB)
Succinyl-CoAMetaboliteHMDB01022 (HMDB)
T02G5.4GeneProductT02G5.4 (Ensembl C. elegans)
T02G5.7GeneProductT02G5.7 (Ensembl C. elegans)
T08B2.7GeneProductT08B2.7 (Ensembl C. elegans)
Thiamine pyrophosphateMetaboliteHMDB01372 (HMDB)
Tiglyl-CoAMetaboliteHMDB02054 (HMDB)
TransketolaseGeneProductY39E4A.3 (WormBase) Original kegg element: gene;12;cel:F27D4.5 cel:Y39E4A.3
Y44A6D.5GeneProduct180361 (Entrez Gene)
Y71G12B.10GeneProductY71G12B.10 (Ensembl C. elegans)
ZK669.4GeneProduct174279 (Entrez Gene)
a-Ketoisovaleric acidMetaboliteHMDB00019 (HMDB)
acdh-10GeneProductT08G2.3 (WormBase) Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5
acdh-3GeneProductK06A5.6 (WormBase) Original kegg element: gene;41;cel:K06A5.6
acdh-7GeneProductT25G12.5 (WormBase) Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5
acdh-8GeneProductK05F1.3 (WormBase)
ard-1GeneProductF01G4.2 (WormBase)
bcat-1GeneProductK02A4.1 (WormBase) Original kegg element: gene;37;cel:K02A4.1 cel:Y44A6D.5
ech-1GeneProductC29F3.1 (WormBase)
ech-2GeneProductF38H4.8 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-3GeneProductF43H9.1 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-5GeneProductF56B3.5 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-6GeneProductT05G5.6 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-7GeneProductY105E8A.4 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-8GeneProductF01G10.2 (WormBase)
ech-9GeneProductF01G10.3 (WormBase)
gta-1GeneProductK04D7.3 (WormBase)
hacd-1GeneProductR09B5.6 (WormBase)
ivd-1GeneProductC02B10.1 (WormBase) Original kegg element: gene;41;cel:K06A5.6
kat-1GeneProductT02G5.8 (WormBase)
pcca-1GeneProductF27D9.5 (WormBase)
pccb-1GeneProductF52E4.1 (WormBase)
tag-173GeneProductF27D4.5 (WormBase) Original kegg element: gene;43;cel:F27D4.5 cel:Y39E4A.3

Annotated Interactions

No annotated interactions

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