Kit Receptor Signaling Pathway (Danio rerio)

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MTCytoplasmMolecule in the pathwayMitochondrionERRecruitmentPhosphorylationDeacetylationExtracellularReceptorEndoplasmic reticulumDp85 complexSumoylationAutophosphorlationCYNUENInhibitionPMCY->PMEnzyme complexEndosomeProteins in a complex interactionAccession Number: NetPath 6; cellmap:6Proteolytic cleavageMethylationUbiquitinationMolecular associationPalmitoylationDControlGene SymbolActivationNucleusPlasma MembraneDemethylationReaction through unknown mechanisms/moleculesDephosphorylationAcetylationGOTranslocationECLigandDeubiquitinationDesumoylationGlycosylation(Protein-protein interaction)Golgi apparatuscblbplcg1raf1rps6ka3asrcBADbtkTRAILR1zgc:77033zgc:175287jak2bplce1crkHRASLOC558703dok1bLOC792354stat1acishcrklep300amap2k1SOS1LOC563639ptpn11CH211-63J24.2yes1STAT5Azgc:92124KITLOC569951GRB7stat3STAP1mapk1LOC559103VAV1ptprugrb2GRAPcblKITLGspred2STAT5Bspred1socs1LOC562032pik3r2CSF2RBKITKITLGLOC100000720LOC560525dok1brasa1LOC792089CLTCSH3KBP1LOC100149498LOC557176prkcb1VAV2epormitfbSOCS5ptpn6FESfynbMPDZSOCS4


Description

No description

Comments

GenMAPP notes 
NetPath 6; cellmap:6 - Kit Receptor Signaling Pathway. The Kit Receptor signaling pathway was kindly reviewed by Imke Ehlers in Peter Besmer’s lab. This cancer signaling pathway is available at Cancer Cell Map (http://cancer.cellmap.org) and NetPath (http://www.netpath.org) and is part of a collaborative project between the Computational Biology Center at Memorial Sloan-Kettering Cancer Center (http://cbio.mskcc.org), PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the Cancer Cell Map and NetPath websites until the pathway is published.
GenMAPP remarks 
http://cancer.cellmap.org; http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP304(r21319) with a 68% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
68692view05:54, 6 July 2013MaintBotUpdated to 2013 gpml schema
67425view10:59, 26 June 2013DdiglesOntology Term : 'Stem Cell Factor signaling pathway' added !
40868view22:20, 1 March 2011MaintBotRemoved redundant pathway information and comments
35760view00:05, 13 February 2010AlexanderPico
34248view21:43, 9 December 2009MaintBotAutomatic update of empty xrefs
31359view20:33, 13 August 2009MaintBotFixed text labels
31051view01:22, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
BADGeneProduct
CH211-63J24.2GeneProduct567405 (Entrez Gene)
CLTCGeneProduct
CSF2RBGeneProduct
FESGeneProduct
GRAPGeneProduct
GRB7GeneProduct
HRASGeneProduct
KITGeneProduct
KITLGGeneProduct
LOC100000720GeneProduct100000720 (Entrez Gene)
LOC100149498GeneProduct100149498 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC558703GeneProduct558703 (Entrez Gene)
LOC559103GeneProduct559103 (Entrez Gene)
LOC560525GeneProduct560525 (Entrez Gene)
LOC562032GeneProduct562032 (Entrez Gene)
LOC563639GeneProduct563639 (Entrez Gene)
LOC569951GeneProduct569951 (Entrez Gene)
LOC792089GeneProduct792089 (Entrez Gene)
LOC792354GeneProduct792354 (Entrez Gene)
MPDZGeneProduct
SH3KBP1GeneProduct
SOCS4GeneProduct
SOCS5GeneProduct
SOS1GeneProduct
STAP1GeneProduct
STAT5AGeneProduct
STAT5BGeneProduct
TRAILR1GeneProduct
VAV1GeneProduct
VAV2GeneProduct
btkGeneProduct568653 (Entrez Gene)
cblGeneProduct492364 (Entrez Gene)
cblbGeneProduct556277 (Entrez Gene)
cishGeneProduct767678 (Entrez Gene)
crkGeneProduct445234 (Entrez Gene)
crklGeneProduct556443 (Entrez Gene)
dok1bGeneProduct406361 (Entrez Gene)
ep300aGeneProduct559273 (Entrez Gene)
eporGeneProduct751109 (Entrez Gene)
fynbGeneProduct574422 (Entrez Gene)
grb2GeneProduct406308 (Entrez Gene)
jak2bGeneProduct30298 (Entrez Gene)
map2k1GeneProduct406728 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mitfbGeneProduct114833 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
plce1GeneProduct568288 (Entrez Gene)
plcg1GeneProduct373867 (Entrez Gene)
prkcb1GeneProduct393953 (Entrez Gene)
ptpn11GeneProduct333979 (Entrez Gene)
ptpn6GeneProduct335573 (Entrez Gene)
ptpruGeneProduct335096 (Entrez Gene)
raf1GeneProduct30716 (Entrez Gene)
rasa1GeneProduct100002155 (Entrez Gene)
rps6ka3aGeneProduct338219 (Entrez Gene)
socs1GeneProduct445073 (Entrez Gene)
spred1GeneProduct406513 (Entrez Gene)
spred2GeneProduct793290 (Entrez Gene)
srcGeneProduct325084 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
stat3GeneProduct30767 (Entrez Gene)
yes1GeneProduct407620 (Entrez Gene)
zgc:175287GeneProduct571588 (Entrez Gene)
zgc:77033GeneProduct406598 (Entrez Gene)
zgc:92124GeneProduct447804 (Entrez Gene)

Annotated Interactions

No annotated interactions
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