Metapathway biotransformation (Rattus norvegicus)
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Sulfotransferases
Glutathione conjugation
Reduction
Hydrolysis
Acetylation
Amino acid acyl transferases
Oxidation
Epoxide hydrolases
Glutathione transferases
Glutathione synthetase
Methylation
Aldo-keto reductases
Glucuronidation
Glutathione peroxidases
Cytochrome P450
Sulfation
Glutathione reductase
Amino acid conjugation
Flavin monooxygenases
Electrophiles
N-acetyltransferases
Nucleophiles
Glucuronosyltransferases
Methyltransferases
Gpx5
Sult1c1
Fmo4
Sulfotransferase
AKR1C2
Ndst3_predicted
CYP3A43
Akr7a2
Cyp2e1
GPX1
Ugt1a6
CYP2C9
LOC683774
Cyp8b1
N-acetyltransferase
Cyp2f2
CYP2C19
Sult1a1
NAT8
Hs2st1
AKR1B1
Ugt2a3_predicted
NAT6
Chst14
GSTM1
NP_001101195.1
GLYATL1
SULT1C4
GSTA2
CYP4F8
Comt
CYP2D6
Chst10
UGT2B7
NP_001100901.1
Sult1a1
CYP4V2
LOC687052
NP_001100289.1
CYP2J2
NAT1
Hs3st4
Hs3st1
HS3ST3A1
Sult1a1
CYP2C8
CYP2A7
Kcnab3
Gstt1
CYP11B2
Gss
Gsto1
Cyp4f39_predicted
CYP3A4
HS6ST3
Ugt1a3
Gstp2
Baat
Hnmt
Ste
Cyp4b1
NP_001102569.1
Gstt2
CYP11B1
CYP27B1
Glucuronosyltransferase
CHSTB_RAT
Akr1a1
GSTZ1
NP_001101226.1
Ugt1a5
Fmo2
Substrate-SO3H
Aldo-keto reductase
AKR1C1
UGT2B4
CYP3A5
Kcnab1
Xenobiotic substrate
Mgst1
UGT2B17
Gstm5
GSTA5
Nat9_predicted
Cyp1a2
Methyltransferase
Ugt1a2
Cyp7a1
UGT1A9
Akr7a3
Flavin monooxygenase
Akr1d1
Cyp26b1
Amino acid acyltransferase
Gm766
Ugt1a3
CYP4F2
Substrate-Ac
Chst1
CYP4X1
Glutathione transferase
Hs3st2
NP_001100901.1
Gsto2
Nat8l_predicted
Mgst2
ST2B1_RAT
Chst7
Sult1b1
GSTA3
Cyp26a1
UGT2B28
Fmo5
Substrate-NH2
MGC108896
Substrate-SG
Ndst1
Fmo3
Fmo1
LOC685402
Chst3
NP_001102065.1
Sult1a1
Chst2_predicted
Cyp2w1_predicted
Cyp19a1
Cyp21a1
Cyp51
CYP2B6
MGST3
Substrate=O
Cyp1b1
Cyp11a1
Cyp2u1
NAT2
CYP27C1
Ugt1a1
NP_001101680.1
NP_001101936.1
Substrate-O-R
GSTA4
UGT1A7
UGT2A2
RGD1562825_predicted
GPX2
AKR1C3
Cyp4f18
Gpx3
Substrate-SH
CHST12
Glyat
NP_001099862.1
NP_001100363.1
SULT4A1
MGC105600
NP_001099351.1
CYP4F12
Substrate-OH
Cyp1a1
Ndst4_predicted
Tpmt
Substrate-CH3
Gsr
Ephx1
Gstk1
Gstm3
GAL3ST1
Cyp20a1
CYP4F11
AKR1C4
CYP4Z1
UGT1A10
Cyp26c1_predicted
SULT1C1
Cyp24a1
UGT2B11
CYP2C18
LOC690611
CYP3A7
NP_001102492.1
SULT1C2
UGT2B15
Substrate-Gl
GLYATL2
GSTA1
Kcnab2
Chst9
NP_001101988.1
LOC681900
CYP2A6
Ephx2
NP_001102534.1
NP_001099210.1
Cyp7b1
Cyp17a1
NP_001101969.1
Gstt2
HS3ST3B1
NP_001102193.1
SULT2A1
Cyp27a1
Ugt2a1
Substrate-Aa
CYP450
AKR1B10
NP_001100897.1
GSTM5
NP_001100974.1
CYP2A13
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP702(r29945)
with a 60% conversion rate.
Quality Tags
Ontology Terms
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Bibliography
No bibliography
History
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Compare
Revision
Action
Time
User
Comment
69345
view
18:52, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67457
view
11:04, 26 June 2013
Ddigles
Ontology Term : 'cellular detoxification pathway' added !
58921
view
05:10, 21 February 2013
MaintBot
Updated Ensembl and UniProt data source
58518
view
20:07, 14 February 2013
MaintBot
Modified title
41657
view
02:34, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34055
view
19:04, 9 December 2009
MaintBot
Automatic update of empty xrefs
33192
view
18:08, 5 November 2009
Khanspers
Modified categories
32303
view
13:17, 15 August 2009
MaintBot
Fixed text labels
31886
view
12:42, 14 August 2009
MaintBot
Fixed group labels
31332
view
20:22, 13 August 2009
MaintBot
Fixed text labels
30952
view
00:43, 30 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AKR1B1
GeneProduct
AKR1B10
GeneProduct
AKR1C1
GeneProduct
AKR1C2
GeneProduct
AKR1C3
GeneProduct
AKR1C4
GeneProduct
Akr1a1
GeneProduct
ENSRNOG00000016727 (Ensembl Rat)
Akr1d1
GeneProduct
ENSRNOG00000013004 (Ensembl Rat)
Akr7a2
GeneProduct
ENSRNOG00000017780 (Ensembl Rat)
Akr7a3
GeneProduct
ENSRNOG00000017899 (Ensembl Rat)
Aldo-keto reductase
GeneProduct
Amino acid acyltransferase
GeneProduct
Baat
GeneProduct
ENSRNOG00000007395 (Ensembl Rat)
CHST12
GeneProduct
CHSTB_RAT
GeneProduct
ENSRNOG00000008885 (Ensembl Rat)
CYP11B1
GeneProduct
CYP11B2
GeneProduct
CYP27B1
GeneProduct
CYP27C1
GeneProduct
CYP2A13
GeneProduct
CYP2A6
GeneProduct
CYP2A7
GeneProduct
CYP2B6
GeneProduct
CYP2C18
GeneProduct
CYP2C19
GeneProduct
CYP2C8
GeneProduct
CYP2C9
GeneProduct
CYP2D6
GeneProduct
CYP2J2
GeneProduct
CYP3A4
GeneProduct
CYP3A43
GeneProduct
CYP3A5
GeneProduct
CYP3A7
GeneProduct
CYP450
GeneProduct
CYP4F11
GeneProduct
CYP4F12
GeneProduct
CYP4F2
GeneProduct
CYP4F8
GeneProduct
CYP4V2
GeneProduct
CYP4X1
GeneProduct
CYP4Z1
GeneProduct
Chst10
GeneProduct
ENSRNOG00000012815 (Ensembl Rat)
Chst14
GeneProduct
691394 (Entrez Gene)
Chst1
GeneProduct
ENSRNOG00000007989 (Ensembl Rat)
Chst2_predicted
GeneProduct
ENSRNOG00000037453 (Ensembl Rat)
Chst3
GeneProduct
ENSRNOG00000000572 (Ensembl Rat)
Chst7
GeneProduct
ENSRNOG00000004258 (Ensembl Rat)
Chst9
GeneProduct
291770 (Entrez Gene)
Comt
GeneProduct
ENSRNOG00000001889 (Ensembl Rat)
Cyp11a1
GeneProduct
ENSRNOG00000008074 (Ensembl Rat)
Cyp17a1
GeneProduct
ENSRNOG00000020035 (Ensembl Rat)
Cyp19a1
GeneProduct
ENSRNOG00000000196 (Ensembl Rat)
Cyp1a1
GeneProduct
ENSRNOG00000019500 (Ensembl Rat)
Cyp1a2
GeneProduct
ENSRNOG00000016173 (Ensembl Rat)
Cyp1b1
GeneProduct
ENSRNOG00000040287 (Ensembl Rat)
Cyp20a1
GeneProduct
ENSRNOG00000017631 (Ensembl Rat)
Cyp21a1
GeneProduct
24298 (Entrez Gene)
Cyp24a1
GeneProduct
ENSRNOG00000013062 (Ensembl Rat)
Cyp26a1
GeneProduct
ENSRNOG00000016750 (Ensembl Rat)
Cyp26b1
GeneProduct
ENSRNOG00000015076 (Ensembl Rat)
Cyp26c1_predicted
GeneProduct
ENSRNOG00000030698 (Ensembl Rat)
Cyp27a1
GeneProduct
ENSRNOG00000017188 (Ensembl Rat)
Cyp2e1
GeneProduct
ENSRNOG00000012458 (Ensembl Rat)
Cyp2f2
GeneProduct
ENSRNOG00000032805 (Ensembl Rat)
Cyp2u1
GeneProduct
ENSRNOG00000011053 (Ensembl Rat)
Cyp2w1_predicted
GeneProduct
ENSRNOG00000022355 (Ensembl Rat)
Cyp4b1
GeneProduct
ENSRNOG00000009741 (Ensembl Rat)
Cyp4f18
GeneProduct
ENSRNOG00000015751 (Ensembl Rat)
Cyp4f39_predicted
GeneProduct
ENSRNOG00000029478 (Ensembl Rat)
Cyp51
GeneProduct
ENSRNOG00000007234 (Ensembl Rat)
Cyp7a1
GeneProduct
ENSRNOG00000009488 (Ensembl Rat)
Cyp7b1
GeneProduct
ENSRNOG00000009730 (Ensembl Rat)
Cyp8b1
GeneProduct
ENSRNOG00000019481 (Ensembl Rat)
Ephx1
GeneProduct
ENSRNOG00000003515 (Ensembl Rat)
Ephx2
GeneProduct
ENSRNOG00000017286 (Ensembl Rat)
Flavin monooxygenase
GeneProduct
Fmo1
GeneProduct
ENSRNOG00000034191 (Ensembl Rat)
Fmo2
GeneProduct
ENSRNOG00000003510 (Ensembl Rat)
Fmo3
GeneProduct
ENSRNOG00000003620 (Ensembl Rat)
Fmo4
GeneProduct
ENSRNOG00000003400 (Ensembl Rat)
Fmo5
GeneProduct
ENSRNOG00000018076 (Ensembl Rat)
GAL3ST1
GeneProduct
GLYATL1
GeneProduct
GLYATL2
GeneProduct
GPX1
GeneProduct
GPX2
GeneProduct
GSTA1
GeneProduct
GSTA2
GeneProduct
GSTA3
GeneProduct
GSTA4
GeneProduct
GSTA5
GeneProduct
GSTM1
GeneProduct
GSTM5
GeneProduct
GSTZ1
GeneProduct
Glucuronosyltransferase
GeneProduct
Glutathione transferase
GeneProduct
Glyat
GeneProduct
ENSRNOG00000012142 (Ensembl Rat)
Gm766
GeneProduct
ENSRNOG00000036959 (Ensembl Rat)
Gpx3
GeneProduct
ENSRNOG00000021809 (Ensembl Rat)
Gpx5
GeneProduct
ENSRNOG00000018596 (Ensembl Rat)
Gsr
GeneProduct
ENSRNOG00000014915 (Ensembl Rat)
Gss
GeneProduct
ENSRNOG00000018964 (Ensembl Rat)
Gstk1
GeneProduct
ENSRNOG00000016484 (Ensembl Rat)
Gstm3
GeneProduct
ENSRNOG00000018937 (Ensembl Rat)
Gstm5
GeneProduct
ENSRNOG00000018732 (Ensembl Rat)
Gsto1
GeneProduct
ENSRNOG00000028746 (Ensembl Rat)
Gsto2
GeneProduct
ENSRNOG00000012801 (Ensembl Rat)
Gstp2
GeneProduct
ENSRNOG00000018237 (Ensembl Rat)
Gstt1
GeneProduct
ENSRNOG00000001242 (Ensembl Rat)
Gstt2
GeneProduct
ENSRNOG00000028188 (Ensembl Rat)
HS3ST3A1
GeneProduct
HS3ST3B1
GeneProduct
HS6ST3
GeneProduct
Hnmt
GeneProduct
ENSRNOG00000005223 (Ensembl Rat)
Hs2st1
GeneProduct
ENSRNOG00000012549 (Ensembl Rat)
Hs3st1
GeneProduct
ENSRNOG00000010598 (Ensembl Rat)
Hs3st2
GeneProduct
ENSRNOG00000017659 (Ensembl Rat)
Hs3st4
GeneProduct
ENSRNOG00000036723 (Ensembl Rat)
Kcnab1
GeneProduct
ENSRNOG00000010422 (Ensembl Rat)
Kcnab2
GeneProduct
ENSRNOG00000011550 (Ensembl Rat)
Kcnab3
GeneProduct
ENSRNOG00000008480 (Ensembl Rat)
LOC681900
GeneProduct
ENSRNOG00000014672 (Ensembl Rat)
LOC683774
GeneProduct
ENSRNOG00000030880 (Ensembl Rat)
LOC685402
GeneProduct
ENSRNOG00000022982 (Ensembl Rat)
LOC687052
GeneProduct
ENSRNOG00000020743 (Ensembl Rat)
LOC690611
GeneProduct
ENSRNOG00000013604 (Ensembl Rat)
MGC105600
GeneProduct
ENSRNOG00000028743 (Ensembl Rat)
MGC108896
GeneProduct
ENSRNOG00000019221 (Ensembl Rat)
MGST3
GeneProduct
Methyltransferase
GeneProduct
Mgst1
GeneProduct
ENSRNOG00000007743 (Ensembl Rat)
Mgst2
GeneProduct
ENSRNOG00000013296 (Ensembl Rat)
N-acetyltransferase
GeneProduct
NAT1
GeneProduct
NAT2
GeneProduct
NAT6
GeneProduct
NAT8
GeneProduct
NP_001099210.1
GeneProduct
ENSRNOG00000027171 (Ensembl Rat)
NP_001099351.1
GeneProduct
ENSRNOG00000039017 (Ensembl Rat)
NP_001099862.1
GeneProduct
ENSRNOG00000000605 (Ensembl Rat)
NP_001100289.1
GeneProduct
ENSRNOG00000005930 (Ensembl Rat)
NP_001100363.1
GeneProduct
ENSRNOG00000010519 (Ensembl Rat)
NP_001100897.1
GeneProduct
ENSRNOG00000016953 (Ensembl Rat)
NP_001100901.1
GeneProduct
ENSRNOG00000021521 (Ensembl Rat)
NP_001100974.1
GeneProduct
ENSRNOG00000022919 (Ensembl Rat)
NP_001101195.1
GeneProduct
ENSRNOG00000011669 (Ensembl Rat)
NP_001101226.1
GeneProduct
ENSRNOG00000008663 (Ensembl Rat)
NP_001101680.1
GeneProduct
ENSRNOG00000014516 (Ensembl Rat)
NP_001101936.1
GeneProduct
ENSRNOG00000038622 (Ensembl Rat)
NP_001101969.1
GeneProduct
ENSRNOG00000011367 (Ensembl Rat)
NP_001101988.1
GeneProduct
ENSRNOG00000021179 (Ensembl Rat)
NP_001102065.1
GeneProduct
ENSRNOG00000010523 (Ensembl Rat)
NP_001102193.1
GeneProduct
ENSRNOG00000007147 (Ensembl Rat)
NP_001102492.1
GeneProduct
ENSRNOG00000011250 (Ensembl Rat)
NP_001102534.1
GeneProduct
ENSRNOG00000001375 (Ensembl Rat)
NP_001102569.1
GeneProduct
ENSRNOG00000014192 (Ensembl Rat)
Nat8l_predicted
GeneProduct
ENSRNOG00000015466 (Ensembl Rat)
Nat9_predicted
GeneProduct
ENSRNOG00000003264 (Ensembl Rat)
Ndst1
GeneProduct
ENSRNOG00000019014 (Ensembl Rat)
Ndst3_predicted
GeneProduct
ENSRNOG00000015781 (Ensembl Rat)
Ndst4_predicted
GeneProduct
ENSRNOG00000009577 (Ensembl Rat)
RGD1562825_predicted
GeneProduct
ENSRNOG00000025930 (Ensembl Rat)
ST2B1_RAT
GeneProduct
ENSRNOG00000021046 (Ensembl Rat)
SULT1C1
GeneProduct
SULT1C2
GeneProduct
SULT1C4
GeneProduct
SULT2A1
GeneProduct
SULT4A1
GeneProduct
Ste
GeneProduct
ENSRNOG00000001957 (Ensembl Rat)
Substrate-Aa
Metabolite
Substrate-Ac
Metabolite
Substrate-CH3
Metabolite
Substrate-Gl
Metabolite
Substrate-NH2
Metabolite
Substrate-O-R
Metabolite
Substrate-OH
Metabolite
Substrate-SG
Metabolite
Substrate-SH
Metabolite
Substrate-SO3H
Metabolite
Substrate=O
Metabolite
Sulfotransferase
GeneProduct
Sult1a1
GeneProduct
ENSRNOG00000019342 (Ensembl Rat)
Sult1b1
GeneProduct
ENSRNOG00000001967 (Ensembl Rat)
Sult1c1
GeneProduct
ENSRNOG00000011269 (Ensembl Rat)
Tpmt
GeneProduct
ENSRNOG00000016468 (Ensembl Rat)
UGT1A10
GeneProduct
UGT1A7
GeneProduct
UGT1A9
GeneProduct
UGT2A2
GeneProduct
UGT2B11
GeneProduct
UGT2B15
GeneProduct
UGT2B17
GeneProduct
UGT2B28
GeneProduct
UGT2B4
GeneProduct
UGT2B7
GeneProduct
Ugt1a1
GeneProduct
24861 (Entrez Gene)
Ugt1a2
GeneProduct
396527 (Entrez Gene)
Ugt1a3
GeneProduct
396551 (Entrez Gene)
Ugt1a3
GeneProduct
ENSRNOG00000018740 (Ensembl Rat)
Ugt1a5
GeneProduct
574523 (Entrez Gene)
Ugt1a6
GeneProduct
113992 (Entrez Gene)
Ugt2a1
GeneProduct
ENSRNOG00000001973 (Ensembl Rat)
Ugt2a3_predicted
GeneProduct
ENSRNOG00000001975 (Ensembl Rat)
Xenobiotic substrate
Metabolite
Annotated Interactions
No annotated interactions
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External references
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Annotated Interactions
No annotated interactions