Metapathway biotransformation (Rattus norvegicus)

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SulfotransferasesGlutathione conjugationReductionHydrolysisAcetylationAmino acid acyl transferasesOxidationEpoxide hydrolasesGlutathione transferasesGlutathione synthetaseMethylationAldo-keto reductasesGlucuronidationGlutathione peroxidasesCytochrome P450SulfationGlutathione reductaseAmino acid conjugationFlavin monooxygenasesElectrophilesN-acetyltransferasesNucleophilesGlucuronosyltransferasesMethyltransferasesGpx5Sult1c1Fmo4SulfotransferaseAKR1C2Ndst3_predictedCYP3A43Akr7a2Cyp2e1GPX1Ugt1a6CYP2C9LOC683774Cyp8b1N-acetyltransferaseCyp2f2CYP2C19Sult1a1NAT8Hs2st1AKR1B1Ugt2a3_predictedNAT6Chst14GSTM1NP_001101195.1GLYATL1SULT1C4GSTA2CYP4F8ComtCYP2D6Chst10UGT2B7NP_001100901.1Sult1a1CYP4V2LOC687052NP_001100289.1CYP2J2NAT1Hs3st4Hs3st1HS3ST3A1Sult1a1CYP2C8CYP2A7Kcnab3Gstt1CYP11B2GssGsto1Cyp4f39_predictedCYP3A4HS6ST3Ugt1a3Gstp2BaatHnmtSteCyp4b1NP_001102569.1Gstt2CYP11B1CYP27B1GlucuronosyltransferaseCHSTB_RATAkr1a1GSTZ1NP_001101226.1Ugt1a5Fmo2Substrate-SO3HAldo-keto reductaseAKR1C1UGT2B4CYP3A5Kcnab1Xenobiotic substrateMgst1UGT2B17Gstm5GSTA5Nat9_predictedCyp1a2MethyltransferaseUgt1a2Cyp7a1UGT1A9Akr7a3Flavin monooxygenaseAkr1d1Cyp26b1Amino acid acyltransferaseGm766Ugt1a3CYP4F2Substrate-AcChst1CYP4X1Glutathione transferaseHs3st2NP_001100901.1Gsto2Nat8l_predictedMgst2ST2B1_RATChst7Sult1b1GSTA3Cyp26a1UGT2B28Fmo5Substrate-NH2MGC108896Substrate-SGNdst1Fmo3Fmo1LOC685402Chst3NP_001102065.1Sult1a1Chst2_predictedCyp2w1_predictedCyp19a1Cyp21a1Cyp51CYP2B6MGST3Substrate=OCyp1b1Cyp11a1Cyp2u1NAT2CYP27C1Ugt1a1NP_001101680.1NP_001101936.1Substrate-O-RGSTA4UGT1A7UGT2A2RGD1562825_predictedGPX2AKR1C3Cyp4f18Gpx3Substrate-SHCHST12GlyatNP_001099862.1NP_001100363.1SULT4A1MGC105600NP_001099351.1CYP4F12Substrate-OHCyp1a1Ndst4_predictedTpmtSubstrate-CH3GsrEphx1Gstk1Gstm3GAL3ST1Cyp20a1CYP4F11AKR1C4CYP4Z1UGT1A10Cyp26c1_predictedSULT1C1Cyp24a1UGT2B11CYP2C18LOC690611CYP3A7NP_001102492.1SULT1C2UGT2B15Substrate-GlGLYATL2GSTA1Kcnab2Chst9NP_001101988.1LOC681900CYP2A6Ephx2NP_001102534.1NP_001099210.1Cyp7b1Cyp17a1NP_001101969.1Gstt2HS3ST3B1NP_001102193.1SULT2A1Cyp27a1Ugt2a1Substrate-AaCYP450AKR1B10NP_001100897.1GSTM5NP_001100974.1CYP2A13


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r29945) with a 60% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
69345view18:52, 8 July 2013MaintBotUpdated to 2013 gpml schema
67457view11:04, 26 June 2013DdiglesOntology Term : 'cellular detoxification pathway' added !
58921view05:10, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
58518view20:07, 14 February 2013MaintBotModified title
41657view02:34, 2 March 2011MaintBotRemoved redundant pathway information and comments
34055view19:04, 9 December 2009MaintBotAutomatic update of empty xrefs
33192view18:08, 5 November 2009KhanspersModified categories
32303view13:17, 15 August 2009MaintBotFixed text labels
31886view12:42, 14 August 2009MaintBotFixed group labels
31332view20:22, 13 August 2009MaintBotFixed text labels
30952view00:43, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKR1B1GeneProduct
AKR1B10GeneProduct
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct
AKR1C4GeneProduct
Akr1a1GeneProductENSRNOG00000016727 (Ensembl Rat)
Akr1d1GeneProductENSRNOG00000013004 (Ensembl Rat)
Akr7a2GeneProductENSRNOG00000017780 (Ensembl Rat)
Akr7a3GeneProductENSRNOG00000017899 (Ensembl Rat)
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
BaatGeneProductENSRNOG00000007395 (Ensembl Rat)
CHST12GeneProduct
CHSTB_RATGeneProductENSRNOG00000008885 (Ensembl Rat)
CYP11B1GeneProduct
CYP11B2GeneProduct
CYP27B1GeneProduct
CYP27C1GeneProduct
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2B6GeneProduct
CYP2C18GeneProduct
CYP2C19GeneProduct
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2D6GeneProduct
CYP2J2GeneProduct
CYP3A4GeneProduct
CYP3A43GeneProduct
CYP3A5GeneProduct
CYP3A7GeneProduct
CYP450GeneProduct
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F2GeneProduct
CYP4F8GeneProduct
CYP4V2GeneProduct
CYP4X1GeneProduct
CYP4Z1GeneProduct
Chst10GeneProductENSRNOG00000012815 (Ensembl Rat)
Chst14GeneProduct691394 (Entrez Gene)
Chst1GeneProductENSRNOG00000007989 (Ensembl Rat)
Chst2_predictedGeneProductENSRNOG00000037453 (Ensembl Rat)
Chst3GeneProductENSRNOG00000000572 (Ensembl Rat)
Chst7GeneProductENSRNOG00000004258 (Ensembl Rat)
Chst9GeneProduct291770 (Entrez Gene)
ComtGeneProductENSRNOG00000001889 (Ensembl Rat)
Cyp11a1GeneProductENSRNOG00000008074 (Ensembl Rat)
Cyp17a1GeneProductENSRNOG00000020035 (Ensembl Rat)
Cyp19a1GeneProductENSRNOG00000000196 (Ensembl Rat)
Cyp1a1GeneProductENSRNOG00000019500 (Ensembl Rat)
Cyp1a2GeneProductENSRNOG00000016173 (Ensembl Rat)
Cyp1b1GeneProductENSRNOG00000040287 (Ensembl Rat)
Cyp20a1GeneProductENSRNOG00000017631 (Ensembl Rat)
Cyp21a1GeneProduct24298 (Entrez Gene)
Cyp24a1GeneProductENSRNOG00000013062 (Ensembl Rat)
Cyp26a1GeneProductENSRNOG00000016750 (Ensembl Rat)
Cyp26b1GeneProductENSRNOG00000015076 (Ensembl Rat)
Cyp26c1_predictedGeneProductENSRNOG00000030698 (Ensembl Rat)
Cyp27a1GeneProductENSRNOG00000017188 (Ensembl Rat)
Cyp2e1GeneProductENSRNOG00000012458 (Ensembl Rat)
Cyp2f2GeneProductENSRNOG00000032805 (Ensembl Rat)
Cyp2u1GeneProductENSRNOG00000011053 (Ensembl Rat)
Cyp2w1_predictedGeneProductENSRNOG00000022355 (Ensembl Rat)
Cyp4b1GeneProductENSRNOG00000009741 (Ensembl Rat)
Cyp4f18GeneProductENSRNOG00000015751 (Ensembl Rat)
Cyp4f39_predictedGeneProductENSRNOG00000029478 (Ensembl Rat)
Cyp51GeneProductENSRNOG00000007234 (Ensembl Rat)
Cyp7a1GeneProductENSRNOG00000009488 (Ensembl Rat)
Cyp7b1GeneProductENSRNOG00000009730 (Ensembl Rat)
Cyp8b1GeneProductENSRNOG00000019481 (Ensembl Rat)
Ephx1GeneProductENSRNOG00000003515 (Ensembl Rat)
Ephx2GeneProductENSRNOG00000017286 (Ensembl Rat)
Flavin monooxygenaseGeneProduct
Fmo1GeneProductENSRNOG00000034191 (Ensembl Rat)
Fmo2GeneProductENSRNOG00000003510 (Ensembl Rat)
Fmo3GeneProductENSRNOG00000003620 (Ensembl Rat)
Fmo4GeneProductENSRNOG00000003400 (Ensembl Rat)
Fmo5GeneProductENSRNOG00000018076 (Ensembl Rat)
GAL3ST1GeneProduct
GLYATL1GeneProduct
GLYATL2GeneProduct
GPX1GeneProduct
GPX2GeneProduct
GSTA1GeneProduct
GSTA2GeneProduct
GSTA3GeneProduct
GSTA4GeneProduct
GSTA5GeneProduct
GSTM1GeneProduct
GSTM5GeneProduct
GSTZ1GeneProduct
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
GlyatGeneProductENSRNOG00000012142 (Ensembl Rat)
Gm766GeneProductENSRNOG00000036959 (Ensembl Rat)
Gpx3GeneProductENSRNOG00000021809 (Ensembl Rat)
Gpx5GeneProductENSRNOG00000018596 (Ensembl Rat)
GsrGeneProductENSRNOG00000014915 (Ensembl Rat)
GssGeneProductENSRNOG00000018964 (Ensembl Rat)
Gstk1GeneProductENSRNOG00000016484 (Ensembl Rat)
Gstm3GeneProductENSRNOG00000018937 (Ensembl Rat)
Gstm5GeneProductENSRNOG00000018732 (Ensembl Rat)
Gsto1GeneProductENSRNOG00000028746 (Ensembl Rat)
Gsto2GeneProductENSRNOG00000012801 (Ensembl Rat)
Gstp2GeneProductENSRNOG00000018237 (Ensembl Rat)
Gstt1GeneProductENSRNOG00000001242 (Ensembl Rat)
Gstt2GeneProductENSRNOG00000028188 (Ensembl Rat)
HS3ST3A1GeneProduct
HS3ST3B1GeneProduct
HS6ST3GeneProduct
HnmtGeneProductENSRNOG00000005223 (Ensembl Rat)
Hs2st1GeneProductENSRNOG00000012549 (Ensembl Rat)
Hs3st1GeneProductENSRNOG00000010598 (Ensembl Rat)
Hs3st2GeneProductENSRNOG00000017659 (Ensembl Rat)
Hs3st4GeneProductENSRNOG00000036723 (Ensembl Rat)
Kcnab1GeneProductENSRNOG00000010422 (Ensembl Rat)
Kcnab2GeneProductENSRNOG00000011550 (Ensembl Rat)
Kcnab3GeneProductENSRNOG00000008480 (Ensembl Rat)
LOC681900GeneProductENSRNOG00000014672 (Ensembl Rat)
LOC683774GeneProductENSRNOG00000030880 (Ensembl Rat)
LOC685402GeneProductENSRNOG00000022982 (Ensembl Rat)
LOC687052GeneProductENSRNOG00000020743 (Ensembl Rat)
LOC690611GeneProductENSRNOG00000013604 (Ensembl Rat)
MGC105600GeneProductENSRNOG00000028743 (Ensembl Rat)
MGC108896GeneProductENSRNOG00000019221 (Ensembl Rat)
MGST3GeneProduct
MethyltransferaseGeneProduct
Mgst1GeneProductENSRNOG00000007743 (Ensembl Rat)
Mgst2GeneProductENSRNOG00000013296 (Ensembl Rat)
N-acetyltransferaseGeneProduct
NAT1GeneProduct
NAT2GeneProduct
NAT6GeneProduct
NAT8GeneProduct
NP_001099210.1GeneProductENSRNOG00000027171 (Ensembl Rat)
NP_001099351.1GeneProductENSRNOG00000039017 (Ensembl Rat)
NP_001099862.1GeneProductENSRNOG00000000605 (Ensembl Rat)
NP_001100289.1GeneProductENSRNOG00000005930 (Ensembl Rat)
NP_001100363.1GeneProductENSRNOG00000010519 (Ensembl Rat)
NP_001100897.1GeneProductENSRNOG00000016953 (Ensembl Rat)
NP_001100901.1GeneProductENSRNOG00000021521 (Ensembl Rat)
NP_001100974.1GeneProductENSRNOG00000022919 (Ensembl Rat)
NP_001101195.1GeneProductENSRNOG00000011669 (Ensembl Rat)
NP_001101226.1GeneProductENSRNOG00000008663 (Ensembl Rat)
NP_001101680.1GeneProductENSRNOG00000014516 (Ensembl Rat)
NP_001101936.1GeneProductENSRNOG00000038622 (Ensembl Rat)
NP_001101969.1GeneProductENSRNOG00000011367 (Ensembl Rat)
NP_001101988.1GeneProductENSRNOG00000021179 (Ensembl Rat)
NP_001102065.1GeneProductENSRNOG00000010523 (Ensembl Rat)
NP_001102193.1GeneProductENSRNOG00000007147 (Ensembl Rat)
NP_001102492.1GeneProductENSRNOG00000011250 (Ensembl Rat)
NP_001102534.1GeneProductENSRNOG00000001375 (Ensembl Rat)
NP_001102569.1GeneProductENSRNOG00000014192 (Ensembl Rat)
Nat8l_predictedGeneProductENSRNOG00000015466 (Ensembl Rat)
Nat9_predictedGeneProductENSRNOG00000003264 (Ensembl Rat)
Ndst1GeneProductENSRNOG00000019014 (Ensembl Rat)
Ndst3_predictedGeneProductENSRNOG00000015781 (Ensembl Rat)
Ndst4_predictedGeneProductENSRNOG00000009577 (Ensembl Rat)
RGD1562825_predictedGeneProductENSRNOG00000025930 (Ensembl Rat)
ST2B1_RATGeneProductENSRNOG00000021046 (Ensembl Rat)
SULT1C1GeneProduct
SULT1C2GeneProduct
SULT1C4GeneProduct
SULT2A1GeneProduct
SULT4A1GeneProduct
SteGeneProductENSRNOG00000001957 (Ensembl Rat)
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2Metabolite
Substrate-O-RMetabolite
Substrate-OHMetabolite
Substrate-SGMetabolite
Substrate-SHMetabolite
Substrate-SO3HMetabolite
Substrate=OMetabolite
SulfotransferaseGeneProduct
Sult1a1GeneProductENSRNOG00000019342 (Ensembl Rat)
Sult1b1GeneProductENSRNOG00000001967 (Ensembl Rat)
Sult1c1GeneProductENSRNOG00000011269 (Ensembl Rat)
TpmtGeneProductENSRNOG00000016468 (Ensembl Rat)
UGT1A10GeneProduct
UGT1A7GeneProduct
UGT1A9GeneProduct
UGT2A2GeneProduct
UGT2B11GeneProduct
UGT2B15GeneProduct
UGT2B17GeneProduct
UGT2B28GeneProduct
UGT2B4GeneProduct
UGT2B7GeneProduct
Ugt1a1GeneProduct24861 (Entrez Gene)
Ugt1a2GeneProduct396527 (Entrez Gene)
Ugt1a3GeneProduct396551 (Entrez Gene)
Ugt1a3GeneProductENSRNOG00000018740 (Ensembl Rat)
Ugt1a5GeneProduct574523 (Entrez Gene)
Ugt1a6GeneProduct113992 (Entrez Gene)
Ugt2a1GeneProductENSRNOG00000001973 (Ensembl Rat)
Ugt2a3_predictedGeneProductENSRNOG00000001975 (Ensembl Rat)
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
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