Signaling of Hepatocyte Growth Factor Receptor (Canis familiaris)

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PRight Click for CommentsCDC42pathwayActinTranscriptionof Cox2AnoikisAP-1Changes in Cytoskeletonand Cell mobilityRHOpathwayExtracellularPTranscriptionCytoplasmPTrancriptionAKT PathwayRAC1pathwayPAK1HGFRASA1MAPK1STAT3GAB1GRB2DOCK1ELK1CRKFOSPTK2MetJUNPTK2BRAP1BPTPN11PTK2CRKLMAP4K1HRASPXNRAF1PTK2BITGB1ITGA1RAP1AMAPK3SRCPXNMAPK8PIK3CAMAP2K1PTENSRCRAPGEF1SOS1MAP2K2


No description


GenMAPP remarks 
Converted to human by
This pathway was inferred from Homo sapiens pathway WP313(r21339) with a 92% conversion rate.

Quality Tags

Ontology Terms



No bibliography


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87666view08:55, 25 July 2016LindarieswijkOntology Term : 'scatter factor/hepatocyte growth factor signaling pathway' added !
68535view22:20, 5 July 2013MaintBotUpdated to 2013 gpml schema
40691view21:50, 1 March 2011MaintBotRemoved redundant pathway information and comments
33976view18:30, 9 December 2009MaintBotAutomatic update of empty xrefs
32255view12:57, 15 August 2009MaintBotFixed text labels
31776view12:10, 14 August 2009MaintBotFixed group labels
31280view20:02, 13 August 2009MaintBotFixed text labels
30731view22:59, 29 July 2009MaintBotNew pathway

External references


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NameTypeDatabase referenceComment
CRKLGeneProduct608125 (Entrez Gene)
DOCK1GeneProduct486934 (Entrez Gene) Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
ELK1GeneProduct491860 (Entrez Gene)
FOSGeneProduct490792 (Entrez Gene)
GAB1GeneProduct483808 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
HGFGeneProduct403441 (Entrez Gene)
ITGA1GeneProduct489210 (Entrez Gene)
ITGB1GeneProduct477956 (Entrez Gene)
JUNGeneProduct609429 (Entrez Gene)
MAP2K1GeneProduct478347 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAP4K1GeneProduct484527 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MAPK8GeneProduct477746 (Entrez Gene)
MetGeneProduct403438 (Entrez Gene)
PAK1GeneProduct607885 (Entrez Gene)
PIK3CAGeneProduct488084 (Entrez Gene)
PTENGeneProduct403832 (Entrez Gene)
PTK2GeneProduct475108 (Entrez Gene)
PTK2BGeneProduct486102 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PXNGeneProduct486299 (Entrez Gene)
RAF1GeneProduct484648 (Entrez Gene)
RAP1AGeneProduct483225 (Entrez Gene)
RAP1BGeneProduct608981 (Entrez Gene)
RAPGEF1GeneProduct491286 (Entrez Gene)
RASA1GeneProduct479158 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene) Son of sevenless homolog 1 (Drosophila) (predicted)
SRCGeneProduct485864 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)

Annotated Interactions

No annotated interactions
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