Electron Transport Chain (OXPHOS system in mitochondria) (Homo sapiens)

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Complex IIIAssemblyKreb CyclepathwayStalkUbiquinol-Cytochrome CReductaseNADH-UbiquinoneOxidoreductaseComplex IF0 ComplexUncoupling ProteinComplex VATP Synthase Succinate-UbiquinoneOxidoreductaseF1 ComplexAdenine NucleotideTranslocatorComplex IVC subunitbinds ATP Synthase betaComplex IICytochrome COxidaseNDUFB3NDUFB1NDUFB4NDUFA4NDUFS5ATP5HND4LNDUFS4COX4I1SuccinateNDUFA8ATP8ND2SDHBNDUFA1COX7A2NDUFV3FADATP5F1ATP5G1COX7A2LCOX7CQP-CSLC25A4NDUFA9ATP5A1ATPIF1NDUFA10COX17ND1UCRCATP5G2UQCRBSCO1ATP5DSDHANDUFB8UQCRFS1ATP5ENADHUQCRNDUFC2NDUFA6DAP13NDUFV2COX5AATP5LCOX7A3NDUFA3O2COX6A1ND6COX3H+COX11SDHDATP5G3NDUFS2UbiquinoneCOX6B1SLC25A6ATP5SATP5C1NDUFAB1NDUFS1NAD+COX1NDUFS7COX8Ae-COX7BFADH2NDUFA5UQCRC1NDUFS3Cytochrome CUCP2ATP5J2NDUFB10SLC25A5COX5BNDUFS6UQCRC2ND3COX2NDUFS8NDUFB2ND5NDUFA2SLC25A27SLC25A14ATP5IATP5BSDHCNDUFB7UQCRHNDUFA7ATP5JCOX6A2ATPCOX6CNDUFB9UCP1UCP3NDUFB5COX7A1ATP5OATP6CYTBNDUFV1H2ONDUFB6SURF1NDUFC1ND4COX15


Description

No description

Quality Tags

Ontology Terms

 

Bibliography

  1. Balsa E, Marco R, Perales-Clemente E, Szklarczyk R, Calvo E, Landázuri MO, Enríquez JA; ''NDUFA4 is a subunit of complex IV of the mammalian electron transport chain.''; Cell Metab, 2012 PubMed Europe PMC
  2. Pitceathly RD, Rahman S, Wedatilake Y, Polke JM, Cirak S, Foley AR, Sailer A, Hurles ME, Stalker J, Hargreaves I, Woodward CE, Sweeney MG, Muntoni F, Houlden H, Taanman JW, Hanna MG; ''NDUFA4 mutations underlie dysfunction of a cytochrome c oxidase subunit linked to human neurological disease.''; Cell Rep, 2013 PubMed Europe PMC
  3. Signes A, Fernandez-Vizarra E; ''Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes.''; Essays Biochem, 2018 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
107324view15:29, 23 September 2019DeSlAdded general lit. ref.
107323view15:27, 23 September 2019DeSlChanged NDUFA4 from complex I to IV (according to 2 lit. refs).
106399view21:30, 28 August 2019KhanspersModified description
106195view12:09, 16 August 2019MaintBotHMDB identifier normalization
105579view06:33, 9 August 2019KhanspersModified description
98163view11:12, 31 July 2018DeSlAdded linkout to assemly PW for Complex 1
98127view15:15, 24 July 2018DeSlRemoved licence number and last modified part.
98126view15:14, 24 July 2018DeSlchanged title slightly
97390view04:58, 14 May 2018Khanspersconnected interaction
97113view22:54, 29 April 2018AlexanderPicoReverted to version '07:58, 16 November 2017' by AlexanderPico
97110view22:20, 29 April 2018WpblockedModified title
95118view14:58, 16 November 2017DeSlFixed nested groups.
89727view09:08, 29 September 2016EgonwReconnected a line and converted to interactions into graphical lines.
86860view07:29, 14 July 2016MkutmonOntology Term : 'electron transport chain pathway' added !
86853view00:43, 14 July 2016AlexanderPicoOntology Term : 'PW:0000034' removed !
86852view00:43, 14 July 2016AlexanderPicoOntology Term : 'PW:0000034' removed !
82216view19:38, 15 September 2015AlexanderPicoFixed Cytochrome C interaction
79220view13:38, 15 March 2015EgonwReplaced the HMDB H2 identifier with H+ from ChEBI.
71266view21:52, 16 October 2013MaintBotAutomated update of data sources
67189view10:18, 26 June 2013Christine ChichesterOntology Term : 'electron transport chain pathway' added !
63179view20:33, 8 May 2013MaintBotUpdating gpml version
62687view21:19, 1 May 2013MaintBotUpdated UniProt data source
45239view18:18, 7 October 2011AlexanderPicoOntology Term : 'oxidative phosphorylation pathway' added !
41171view23:42, 1 March 2011MaintBotRemoved redundant pathway information and comments
38660view13:52, 23 September 2010FerryJagersLinked TCA Cycle
37857view19:09, 12 July 2010Khansperschanged arrow
37856view19:06, 12 July 2010Khanspersminor layout change
35237view19:41, 11 February 2010AlexanderPicoModified description
34806view00:05, 21 January 2010KhanspersModified description
34445view18:20, 10 December 2009MaintBotAutomatic update of empty xrefs
32230view12:49, 15 August 2009MaintBotFixed text labels
31735view11:58, 14 August 2009MaintBotFixed group labels
20917view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:Electron Transport Chain]] moved to [[Pathway:WP111]]: Moved to stable identifier
14979view19:48, 24 May 2008AlexanderPicominor fixes
14823view07:24, 24 May 2008AlexanderPicoConnected!
14820view07:17, 24 May 2008AlexanderPicoPeriodical save, work in progress
14818view07:07, 24 May 2008AlexanderPicoPeriodical save, work in progress
14814view06:56, 24 May 2008AlexanderPicoPeriodical save, work in progress
14811view06:46, 24 May 2008AlexanderPicoPeriodical save, work in progress
14809view06:36, 24 May 2008AlexanderPicoPeriodical save, work in progress
14807view06:25, 24 May 2008AlexanderPicoPeriodical save, work in progress
14805view06:15, 24 May 2008AlexanderPicoPeriodical save, work in progress
14802view06:05, 24 May 2008AlexanderPicoPeriodical save, work in progress
14800view05:54, 24 May 2008AlexanderPicoPeriodical save, work in progress
14797view05:44, 24 May 2008AlexanderPicoPeriodical save, work in progress
14795view05:34, 24 May 2008AlexanderPicoPeriodical save, work in progress
14793view05:26, 24 May 2008AlexanderPicoLabels fixed
14790view05:24, 24 May 2008AlexanderPicoPeriodical save, work in progress
14788view05:19, 24 May 2008AlexanderPicoGrouped
13061view11:12, 17 May 2008MaintBotautomated metabolite conversion

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATP5A1GeneProduct498 (Entrez Gene)
ATP5BGeneProduct506 (Entrez Gene)
ATP5C1GeneProduct509 (Entrez Gene)
ATP5DGeneProduct513 (Entrez Gene)
ATP5EGeneProduct514 (Entrez Gene)
ATP5F1GeneProduct515 (Entrez Gene)
ATP5G1GeneProduct516 (Entrez Gene)
ATP5G2GeneProduct517 (Entrez Gene)
ATP5G3GeneProduct518 (Entrez Gene)
ATP5HGeneProduct10476 (Entrez Gene)
ATP5IGeneProduct521 (Entrez Gene)
ATP5J2GeneProduct9551 (Entrez Gene)
ATP5JGeneProduct522 (Entrez Gene)
ATP5LGeneProduct10632 (Entrez Gene)
ATP5OGeneProduct539 (Entrez Gene)
ATP5SGeneProduct27109 (Entrez Gene)
ATP6GeneProduct4508 (Entrez Gene)
ATP8GeneProduct4509 (Entrez Gene)
ATPMetaboliteC00002 (Kegg Compound)
ATPIF1GeneProduct93974 (Entrez Gene)
COX11GeneProduct1353 (Entrez Gene)
COX1GeneProduct4512 (Entrez Gene)
COX15GeneProduct1355 (Entrez Gene)
COX17GeneProduct10063 (Entrez Gene)
COX2GeneProduct4513 (Entrez Gene)
COX3GeneProduct4514 (Entrez Gene)
COX4I1GeneProduct1327 (Entrez Gene)
COX5AGeneProduct9377 (Entrez Gene)
COX5BGeneProduct1329 (Entrez Gene)
COX6A1GeneProduct1337 (Entrez Gene)
COX6A2GeneProduct1339 (Entrez Gene)
COX6B1GeneProduct1340 (Entrez Gene)
COX6CGeneProduct1345 (Entrez Gene)
COX7A1GeneProduct1346 (Entrez Gene)
COX7A2GeneProduct1347 (Entrez Gene)
COX7A2LGeneProduct9167 (Entrez Gene)
COX7A3GeneProductO60397 (SwissProt)
COX7BGeneProduct1349 (Entrez Gene)
COX7CGeneProduct1350 (Entrez Gene)
COX8AGeneProduct1351 (Entrez Gene)
CYTBGeneProduct4519 (Entrez Gene)
Cytochrome CMetaboliteC00524 (Kegg Compound)
DAP13GeneProduct55967 (Entrez Gene)
FADMetaboliteC00016 (Kegg Compound)
FADH2MetaboliteC01352 (Kegg Compound)
H+MetaboliteHMDB01362 (HMDB)
H2OMetaboliteHMDB02111 (HMDB)
NAD+MetaboliteC00003 (Kegg Compound)
NADHMetaboliteC00004 (Kegg Compound)
ND1GeneProduct4535 (Entrez Gene)
ND2GeneProduct4536 (Entrez Gene)
ND3GeneProduct4537 (Entrez Gene)
ND4GeneProduct4538 (Entrez Gene)
ND4LGeneProduct4539 (Entrez Gene)
ND5GeneProduct4540 (Entrez Gene)
ND6GeneProduct4541 (Entrez Gene)
NDUFA10GeneProduct4705 (Entrez Gene)
NDUFA1GeneProduct4694 (Entrez Gene)
NDUFA2GeneProduct4695 (Entrez Gene)
NDUFA3GeneProduct4696 (Entrez Gene)
NDUFA4GeneProduct4697 (Entrez Gene)
NDUFA5GeneProduct4698 (Entrez Gene)
NDUFA6GeneProduct4700 (Entrez Gene)
NDUFA7GeneProduct4701 (Entrez Gene)
NDUFA8GeneProduct4702 (Entrez Gene)
NDUFA9GeneProduct4704 (Entrez Gene)
NDUFAB1GeneProduct4706 (Entrez Gene)
NDUFB10GeneProduct4716 (Entrez Gene)
NDUFB1GeneProduct4707 (Entrez Gene)
NDUFB2GeneProduct4708 (Entrez Gene)
NDUFB3GeneProduct4709 (Entrez Gene)
NDUFB4GeneProduct4710 (Entrez Gene)
NDUFB5GeneProduct4711 (Entrez Gene)
NDUFB6GeneProduct4712 (Entrez Gene)
NDUFB7GeneProduct4713 (Entrez Gene)
NDUFB8GeneProduct4714 (Entrez Gene)
NDUFB9GeneProduct4715 (Entrez Gene)
NDUFC1GeneProduct4717 (Entrez Gene)
NDUFC2GeneProduct4718 (Entrez Gene)
NDUFS1GeneProduct4719 (Entrez Gene)
NDUFS2GeneProduct4720 (Entrez Gene)
NDUFS3GeneProduct4722 (Entrez Gene)
NDUFS4GeneProduct4724 (Entrez Gene)
NDUFS5GeneProduct4725 (Entrez Gene)
NDUFS6GeneProduct4726 (Entrez Gene)
NDUFS7GeneProduct374291 (Entrez Gene)
NDUFS8GeneProduct4728 (Entrez Gene)
NDUFV1GeneProduct4723 (Entrez Gene)
NDUFV2GeneProduct4729 (Entrez Gene)
NDUFV3GeneProduct4731 (Entrez Gene)
O2MetaboliteHMDB01377 (HMDB)
QP-CGeneProduct27089 (Entrez Gene)
SCO1GeneProduct6341 (Entrez Gene)
SDHAGeneProduct6389 (Entrez Gene)
SDHBGeneProduct6390 (Entrez Gene)
SDHCGeneProduct6391 (Entrez Gene)
SDHDGeneProduct6392 (Entrez Gene)
SLC25A14GeneProduct9016 (Entrez Gene)
SLC25A27GeneProduct9481 (Entrez Gene)
SLC25A4GeneProduct291 (Entrez Gene)
SLC25A5GeneProduct292 (Entrez Gene)
SLC25A6GeneProduct293 (Entrez Gene)
SURF1GeneProduct6834 (Entrez Gene)
SuccinateMetaboliteC00042 (Kegg Compound)
UCP1GeneProduct7350 (Entrez Gene)
UCP2GeneProduct7351 (Entrez Gene)
UCP3GeneProduct7352 (Entrez Gene)
UCRCGeneProduct29796 (Entrez Gene)
UQCRGeneProduct10975 (Entrez Gene)
UQCRBGeneProduct7381 (Entrez Gene)
UQCRC1GeneProduct7384 (Entrez Gene)
UQCRC2GeneProduct7385 (Entrez Gene)
UQCRFS1GeneProduct7386 (Entrez Gene)
UQCRHGeneProduct7388 (Entrez Gene)
UbiquinoneUnknown303-97-9 (CAS)
e-MetaboliteC05359 (Kegg Compound)

Annotated Interactions

No annotated interactions

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